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#electrophiles โ€” Public Fediverse posts

Live and recent posts from across the Fediverse tagged #electrophiles, aggregated by home.social.

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  1. Stephan Hacker @[email protected] ยท

    ๐‡๐จ๐ฐ ๐œ๐š๐ง ๐ฒ๐จ๐ฎ ๐›๐ž๐ฌ๐ญ ๐š๐ฌ๐ฌ๐ž๐ฌ๐ฌ ๐ญ๐ก๐ž ๐ฌ๐ญ๐š๐›๐ข๐ฅ๐ข๐ญ๐ฒ ๐จ๐Ÿ ๐œ๐จ๐ฏ๐š๐ฅ๐ž๐ง๐ญ ๐ข๐ง๐ก๐ข๐›๐ข๐ญ๐จ๐ซ๐ฌ ๐Ÿ๐จ๐ซ ๐Ÿ๐ฎ๐ซ๐ญ๐ก๐ž๐ซ ๐๐ž๐ฏ๐ž๐ฅ๐จ๐ฉ๐ฆ๐ž๐ง๐ญ?

    An interesting paper by the group of Jeffrey Keillor in the Journal of Medicinal Chemistry addresses this important question. (1/4)

    doi.org/10.1021/acs.jmedchem.6
    #Chemistry #ChemBio #DrugDiscovery #CovalentDrugs #Electrophiles

    #chemistry #chembio #drugdiscovery #covalentdrugs #electrophiles
  2. Stephan Hacker @[email protected] ยท

    Insightful talk by Dieuwertje Streefkerk at #NWOCHAINS. She talked about their synthetic work on stereochemically defined sulfur(VI) electrophiles and their use as #CovalentInhibitors on the example of chymotrypsin inhibition.

    onlinelibrary.wiley.com/doi/ab
    onlinelibrary.wiley.com/doi/fu
    #Chemistry #ChemBio #Electrophiles

    #nwochains #covalentinhibitors #chemistry #chembio #electrophiles
  3. Stephan Hacker @[email protected] ยท

    Insightful presentation by Minjia Tan at #ISCPDD. She talked about her groupโ€™s research into the use of the photoactivated ortho-nitrobenzyl alcohol (oNBA) reactive group and its application to studying protein complexes in live cells.
    onlinelibrary.wiley.com/doi/10
    #ChemSky #ChemBio #Electrophiles #Crosslinking #XLMS

    #iscpdd #chemsky #chembio #electrophiles #crosslinking #xlms
  4. Stephan Hacker @[email protected] ยท

    A big thank you also to Stacey Paiva and her team at Nature Chemistry for their support and patience with me.

    #CovalentInhibitor #DrugDiscovery #Proteomics #ChemicalProteomics #MassSpectrometry #Electrophiles #ProudPI #AcademicLife #NewPublication #Chemistry #ChemBio
    (6/7)

    #covalentinhibitor #drugdiscovery #proteomics #chemicalproteomics #massspectrometry #electrophiles