#kras — Public Fediverse posts

Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.

https://www.linkedin.com/posts/stan-van-boeckel-a0089b15_part-27-drug-discovery-on-an-undruggable-activity-7452806289342164992-ii04?utm_source=share&utm_medium=member_desktop&rcm=ACoAACVzmDsB7J_8sWXEOBYlnnAs1T4cVcDlrxQ

#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor

Backstage delle riprese del docufilm "Eco del carso".

"Eco del carso" backstage (Ungaretti' s docufilm).

#ww1 #history #storia #primaguerramondiale #carso #kars #kras #ww1stories #Ungaretti #docufilm

Bella passeggiata carsica sul monte Lanaro stamattina. :blobcat:
#Trieste #Kras

Off-the-shelf #cancer #vaccine elicits strong #immune response in #patients with #pancreatic and #colorectal cancer. Final trial results show durable #Tcell responses and reduced #relapse in patients with pancreatic and colorectal cancer https://www.uclahealth.org/news/release/shelf-cancer-vaccine-elicits-strong-immune-response-patients #medicine #science #research #KRAS patients https://www.uclahealth.org/news/release/shelf-cancer-vaccine-elicits-strong-immune-response-patients #health #HealthResearch #healthcare

Cerimonia presso il museo di Kobarid sulla ricorrenza del 110° anniversario dagli inizi della guerra sul fronte dell'Isonzo.

110 years from the start of the Great War on the Isonzo front.
(Kobarid museum)

#ww1 #storia #history #kras #carso #isonzo #front #ww1storytelling #storytelling

“Loomans-Kropp is especially excited about the drug's potential in treating a common type of colon cancer caused by a mutated KRAS gene, which tends to be very tough to treat.” #dna #isogg #epigenetics #coloncancer #metformin #KRAS

https://www.businessinsider.com/metformin-being-studied-colon-cancer-stopping-supplement-2025-5

We flew our kite above a hillfort of St.Mary of the Snows on Podgorje karst, Slovenia.

This story starts with Neolithic dentirstry, goes through Bronze and Iron Age, and ends with a cute little church. Enjoy! ;-)

https://kapjasa.si/en/mothers-and-goddesses/

#kiteaerialphotography #KAP #history #archaeology #hollfort #church #karst #neolithic #bronzeage #ironage #karst #kras #podgorje #kaštelir #kite #kiteflying #aerial #flying #Slovenia

Dal promontorio carsico del Monte Sei Busi è possibile osservare il centro visite Gradina (Doberdò del lago, GO).

From the carsic upland of the "Six holes mountain" you can see Gradina's visitor center (Doberdò del lago, GO).

#ww1 #ww1ww2historywarfronts #grandeguerra #doberdob #carso #kras #storia

#mosstodon #Carso #Kras #Trieste

Gud morning from Repnič!

#Trieste #Carso #Kras

#Protests against #water cuts continue in #Dagestan

About 200 residents of Dagestan blocked the Astrakhan-Makhachkala federal highway in the #Kumtorkalinsky district of the republic. The #demonstrators demanded to take action in connection with the long absence of water in their homes. The section on the 470th kilometer of the road turned out to be blocked, the #protesters took to the road around 20:00.

“During the blocking of the road, a conflict arose between people demanding water supply to their homes, and drivers, outraged by the #fact of blocking the road and stopping traffic,” the police said. #Employees of the Ministry of Internal Affairs intervened in the conflict, to the so-called. More than 50 police officers were involved in "enforcing order". An hour and a half later, by 21:36, traffic was restored in the blocked area.

A traffic jam formed at the scene of the incident, 30 police officers began to regulate traffic to eliminate it. “In the course of communication with #citizens, the conflict was extinguished. At present, the citizens have dispersed, the situation is under control,” the Ministry of Internal Affairs noted.

In this microdistrict, the supply of water and electricity has been turned off for a week, writes the telegram channel Mash Gor.

In the middle of last week, residents of Makhachkala blocked one of the central streets of the city due to power outages. The population of several cities and regions of the republic was left without electricity due to the heat that is in the region. The Dagestan authorities attributed the interruptions to the established abnormally hot weather (up to 43 degrees Celsius) and promised to suppress the protests.

As usual, the authorities blame everything... the population itself. "The current situation is primarily due to the chaotic high-rise buildings, the uncalculated capacity of energy facilities and illegal connections to the power grid," the prosecutor's office says. Prosecutor General Igor Krasnov instructed to deal with the situation in the republic. The Investigative Committee opened a criminal case under the article on negligence (part 1 of article 293 of the Criminal Code) due to "long" and "systematic" blackouts

From #KRAS, #Russian section of the #IWA.

https://t.me/IWA_AIT

'Using two independent real-world datasets from three different countries and an independent validation cohort based on the global, double-blind, placebo-controlled, phase 3 RECOURSE trial, we demonstrate that codon-specific KRAS mutations predict OS benefit for patients treated with the chemotherapeutic agent FTD/TPI in late-stage mCRC.'

#NatureMedicine #KRAS #PrecisionMedicine

https://www.nature.com/articles/s41591-023-02240-8#Sec7

Debela griža #hillfort as seen from a kite. Check out the full story about this BronzeAge beauty in Slovenia

https://kapjasa.si/en/a-prehistoric-jewel-debela-griza-hillfort/

#kiteaerialphotography #KAP #kite #kiteflying #aerial #photography #prehistoric #settlement #BronzeAge #IronAge #history #archaeology #DebelaGriža #VolčjiGrad #kras #enclosure #hillfort #walls #karst #Ricoh #RicohGR #rokkaku #Rokker #Slovenia

A fascinating prehistoric settlement of Debela griža near Volčji grad, Kras, Slovenia, as seen from a kite.

This double-walled enclosure dates back to the Bronze age (around 1200 BC).

Kite aerial panorama made from photos shot with Ricoh GR on a Rokker kite.

#kiteaerialphotography #KAP #kite #kiteflying #aerial #photography #prehistoric #settlement #BronzeAge #IronAge #history #archaeology #DebelaGriža #VolčjiGrad #kras #enclosure #hillfort #walls #karst #Ricoh #RicohGR #Rokker #Slovenia

Hello everyone, I'm a scientist who now writes about cool science in the oncology arena. Currently interested in #TPD #KRAS #MYC and other emerging areas of interest.

💕Artist: #KRASertres ( #KRAS )
- in City: #Kyiv Ukraine 🇺🇦 2017 - Title: "Mente, cuerpo y alma" - #streetart #art #mural #mastoart #StandWithUkraine 🇺🇦

💕Artist: #KRASertres ( #KRAS )
- in City: #Kramatorsk Akademicheskaya, 41, Ukraine 🇺🇦 2019 - Title: "Yo soy Korsak"- #streetart #art #mastoart #mural #StandWithUkraine