#proteoprobes — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #proteoprobes, aggregated by home.social.
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Do you have experience in Organic Synthesis or Chemical Biology and are you looking for an exciting #postdoc position, in which you can apply your skills to the most exciting questions in microbiology? There are great opportunities available in the lab of Aaron Wright at Baylor University!
#Chemistry #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #Synthesis #Microbes
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Do you have experience in Organic Synthesis or Chemical Biology and are you looking for an exciting #postdoc position, in which you can apply your skills to the most exciting questions in microbiology? There are great opportunities available in the lab of Aaron Wright at Baylor University!
#Chemistry #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #Synthesis #Microbes
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Do you have experience in Organic Synthesis or Chemical Biology and are you looking for an exciting #postdoc position, in which you can apply your skills to the most exciting questions in microbiology? There are great opportunities available in the lab of Aaron Wright at Baylor University!
#Chemistry #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #Synthesis #Microbes
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Congratulations to all authors! (4/4)
#ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #CovalentInhibitor
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Congratulations to all authors! (4/4)
#ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting paper by the group of Rolf Breinbauer in Organic & Biomolecular Chemistry. They synthesized three α-fluoromethyl naphthoquinone-based probes as potentially reduction-activated probes for oxidoreductases, but found promiscuous reactivity.
https://pubs.rsc.org/en/content/articlelanding/2025/ob/d5ob01320h
#Chemistry #ChemBio #ABPP #ChemPro #ProteoProbes #ChemicalProteomics -
Interesting paper by the group of Rolf Breinbauer in Organic & Biomolecular Chemistry. They synthesized three α-fluoromethyl naphthoquinone-based probes as potentially reduction-activated probes for oxidoreductases, but found promiscuous reactivity.
https://pubs.rsc.org/en/content/articlelanding/2025/ob/d5ob01320h
#Chemistry #ChemBio #ABPP #ChemPro #ProteoProbes #ChemicalProteomics -
We explored the question, from which different areas of chemistry, including glycochemistry, peptide chemistry, materials chemistry and synthetic method development new electrophiles for covalent inhibitors can originate in order to keep expanding the druggable space. (2/2)
#Chemistry #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #Glycotime #Peptides #Materials #Synthesis #Undruggable #CovalentInhibitors
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We explored the question, from which different areas of chemistry, including glycochemistry, peptide chemistry, materials chemistry and synthetic method development new electrophiles for covalent inhibitors can originate in order to keep expanding the druggable space. (2/2)
#Chemistry #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #Glycotime #Peptides #Materials #Synthesis #Undruggable #CovalentInhibitors
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Interesting talk by Weining Zhao at #ISCPDD. He talked about the use of #ChemicalProteomics to study the target proteins of Fraxetin. They identified PTGR2 as a relevant target in human cells.
https://pubs.rsc.org/en/content/articlelanding/2025/cc/d4cc05681g
#ABPP #AfBPP #Chemistry #ChemBio #ProteoProbes #ChemPro -
Interesting talk by Weining Zhao at #ISCPDD. He talked about the use of #ChemicalProteomics to study the target proteins of Fraxetin. They identified PTGR2 as a relevant target in human cells.
https://pubs.rsc.org/en/content/articlelanding/2025/cc/d4cc05681g
#ABPP #AfBPP #Chemistry #ChemBio #ProteoProbes #ChemPro -
Very excited to visit Radboud University Nijmegen and to speak at the IMM colloquium. Looking forward to a full day of scientific exchange.
I am excited to present some of the newest work that our group performed at the @LED3hub in a brand new presentation. Curious how it will go and what the feedback will be.
Thank you for inviting me, Kevin Neumann.
#Chemistry #ChemBio #ChemPro #ProteoProbes #ChemicalProteomics
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Very excited to visit Radboud University Nijmegen and to speak at the IMM colloquium. Looking forward to a full day of scientific exchange.
I am excited to present some of the newest work that our group performed at the @LED3hub in a brand new presentation. Curious how it will go and what the feedback will be.
Thank you for inviting me, Kevin Neumann.
#Chemistry #ChemBio #ChemPro #ProteoProbes #ChemicalProteomics
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Amazing lecture by Hui Ye at #ISCPDD. She talked about her group’s exciting research into target responsive accessibility profiling (TRAP) to characterize the binding sites of covalent and non-covalent protein binders in complex environments using #ChemicalProteomics.
https://www.nature.com/articles/s41589-023-01355-w
#Chemistry #ChemBio #ChemPro #ProteoProbes -
Amazing lecture by Hui Ye at #ISCPDD. She talked about her group’s exciting research into target responsive accessibility profiling (TRAP) to characterize the binding sites of covalent and non-covalent protein binders in complex environments using #ChemicalProteomics.
https://www.nature.com/articles/s41589-023-01355-w
#Chemistry #ChemBio #ChemPro #ProteoProbes -
It was great that I could present our work at #ISCPDD. I focused on the isoDTB tags (https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201912075) and our recent Nature Chemistry publication on the selectivity of diverse electrophiles (https://www.nature.com/articles/s41557-025-01902-z).
#ChemBio #Chemistry #ChemPro #ProteoProbes #ChemicalProteomics
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It was great that I could present our work at #ISCPDD. I focused on the isoDTB tags (https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201912075) and our recent Nature Chemistry publication on the selectivity of diverse electrophiles (https://www.nature.com/articles/s41557-025-01902-z).
#ChemBio #Chemistry #ChemPro #ProteoProbes #ChemicalProteomics
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Great talk by Xiaoguang Lei at #ISCPDD. He talked about the identification of novel biosynthetic enzymes using #ChemicalProteomics and the use photoaffinity probes based on biosynthetic intermediates to fish for the relevant enzymes to identify e.g. an intermolecular Diels-Alderase.
https://www.nature.com/articles/s41557-020-0467-7
#Chemistry #ChemBio #ChemPro #ProteoProbes