#inhibitor — Public Fediverse posts

Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.

https://www.linkedin.com/posts/stan-van-boeckel-a0089b15_part-27-drug-discovery-on-an-undruggable-activity-7452806289342164992-ii04?utm_source=share&utm_medium=member_desktop&rcm=ACoAACVzmDsB7J_8sWXEOBYlnnAs1T4cVcDlrxQ

#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor

https://www.europesays.com/ch/53815/ Safety concerns continue to plague Roche’s BTK inhibitor in RMS #BTK #EfficacyData #inhibitor #LiverEnzymeElevations #patients #Roche #SafetyConcerns

The virus entry #inhibitor ARN-75039 provides therapeutic #protection against #Lassa virus infection in guinea pigs, https://etidiohnew.blogspot.com/2026/04/the-virus-entry-inhibitor-arn-75039.html

https://www.europesays.com/ch/35527/ Novartis agrees to acquire a pan-mutant-selective PI3Kα inhibitor, strengthening its breast cancer pipeline #a #acquire #agrees #breast #cancer #inhibitor #Its #Novartis #PanMutantSelective #PI3Kα #pipeline #strengthening #to

A #clinical #SARS-CoV-2 #Mpro #inhibitor blocks replication of multiple #enteroviruses and confers oral in vivo protection in animal models, https://etidiohnew.blogspot.com/2026/03/a-clinical-sars-cov-2-mpro-inhibitor.html

Coadministration of #ribavirin and #arenaviral entry #inhibitor LHF-535 enhances antiviral benefit against authentic #Lassa virus, https://etidiohnew.blogspot.com/2025/04/coadministration-of-ribavirin-and.html

Unveiling the ethylene-inhibiting mechanism of the allelochemical Myrigalone A 🌱🧪

👉 https://www.mauromaver.eu/posts/posts_omnia/focus_II/2/

#Science #Research #academia #PlantScience #Plant #scientificwriting #editorial #allelopathy #ethylene #inhibitor

#Synergistic activity of an #RNA #polymerase PA-PB1 interaction #inhibitor with #oseltamivir vs #human & avian #influenza viruses in #cell culture & in ovo, Antiviral Res.: https://www.sciencedirect.com/science/article/abs/pii/S016635422400189X?via%3Dihub

The PA-PB1 interaction inhibitor '54' acts synergistically with oseltamivir vs influenza A & B. '54' & oseltamivir combined at low doses inhibit viral progeny production & proteins expression in cell culture. 54 inhibits avian influenza replication both in cell culture & in embryonated chicken eggs.

#Efficacy of #host #cell serine #protease #inhibitor MM3122 against #SARS-CoV-2 for #treatment and #prevention of #COVID19, J Virol.: https://doi.org/10.1128/jvi.01903-23

Herein, we demonstrate that MM3122 potently inhibits viral replication in human lung epithelial cells and is also effective against the EG.5.1 variant of SARS-CoV-2.