#medicines — Public Fediverse posts

https://www.europesays.com/ch/125250/ Roche Pharma India launches customer experience centre in Chennai | Company News #Chennai #Medicines #PharmaIndustry #PharmaSector #Roche

Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.

https://www.linkedin.com/posts/stan-van-boeckel-a0089b15_part-27-drug-discovery-on-an-undruggable-activity-7452806289342164992-ii04?utm_source=share&utm_medium=member_desktop&rcm=ACoAACVzmDsB7J_8sWXEOBYlnnAs1T4cVcDlrxQ

#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor

Who needs #BioLabs when there's all sorts of #bacteria about to be exposed after thousands of years!

Researchers issue warning after making grim #Antarctic discovery: 'We are only beginning to understand'

Story by Daysia Tolentino, January 29, 2026

Excerpt: "A study published in the journal #Biocontaminant examined the effects of #GlacialMelting on our #WaterSupply.

"#Glaciers serve as reservoirs for #AntibioticResistanceGenes, or #ARGs, and other #microbes. When they are released from the ice, they enter our water systems, posing a major health risk to people downstream.

"Millions of people get their water from glacier-fed rivers and lakes. ARGs are strands of DNA that make bacteria more resistant to drugs. When ARGs in #meltwater make their way into our water supply, they become a global public health risk.

"The study emphasizes the importance of viewing glaciers, rivers, and lakes as being part of a 'glacier continuum.' This means they are an interconnected system rather than separate environments.

Why are melting glaciers concerning?

"From our gas-powered cars to #overconsumption, human activity has contributed to the production of heat-trapping gases that warm the planet. Rising global temperatures have caused glaciers to rapidly melt, causing elevated sea levels and releasing ARGs.

"ARGs from melting glaciers are worrisome because they help facilitate the spread of diseases. This threat is compounded by the fact that our growing #microplastic problem is also helping #AntibioticResistant #bacteria breed. As a result, #medicines are being rendered less effective."

https://www.msn.com/en-us/weather/topstories/researchers-issue-warning-after-making-grim-antarctic-discovery-we-are-only-beginning-to-understand/

#WorldPol #USPol #FossilFuels #FossilFools #Degrowth #RenewablesNow #WaterIsLife #OceansAreLife #HumanFolly #NewDiseases

Well this is a disturbing development, are the drugs we use what they seem?
I've seen how regulation has collapsed in America, I hope we're not following down that same Libertarian shit show?

https://www.theguardian.com/world/2025/oct/24/northampton-factory-making-counterfeit-weight-loss-jabs-raided

#Drugs #Medicines #UKCrime #retatrutide #tirzepatide

#Wabanaki group restoring 245-acre farm in #SwanvilleME as food hub

#Niweskok, a Wabanaki-led #FoodSovereignty organization, recently bought the farm to aid its work reinvigorating traditional crops and land management.

by Gillian Graham, May 8, 2025

"A Wabanaki-led food sovereignty organization recently acquired a 245-acre farm in Swanville, marking the return of Wabanaki stewardship to ancestral lands in the Penobscot Bay region.

"Niweskok: From the #StarsToSeeds, a collaboration of Wabanaki #FoodAndMedicine providers, has focused for years on reinvigorating #TraditionalCrops and #LandManagement strategies, distributing #TraditionalFoods and hosting workshops. But they did not have a permanent land base until buying the farm.

" 'Now, with this land, we have permanency of place — and the ability to continue this work for generations to come,' said #AliviaMoore, a #PenobscotNation citizen and Niweskok co-director.

"Niweskok (which translates to 'dried seeds for planting' in the Penobscot language) raised more than $1.8 million in just three months to buy the farm, which had been used to raise cattle and board horses. The group continues to raise money toward its $3 million capital campaign goal.

"Acquiring the land in January was a major step toward restoring the #PenobscotBay region as a Wabanaki food hub and allows Indigenous communities to reconnect with #TraditionalFoodways, #medicines and #ecological #stewardship. Niweskok sees the land as an intergenerational center where Wabanaki values of care, reciprocity and sustainability can flourish.
Moore said the land will allow Niweskok to go much deeper in its food production work. The group’s plans for the land include educational programming, #SeedSaving, #WildHarvesting and cultural camps.

"Moore said the land itself would determine the name of the farm. The farm was selected because it is close to the ocean and Penobscot territory.
'Penobscot people have been, through the process of #colonization and #genocide, thoroughly removed from coastal access,' Moore said. 'So for us to truly have healthful economies, healthful social structures and political systems, we need to be able to engage in our coastal ecology.'

"The land, with access to the #GooseRiver, includes agricultural #fields, 140 acres of #forest, #wetlands and ponds. There are miles of riding trails through the woods, which Niweskok staff will map and decide which to maintain and whether more are needed for waterway access.

"Niweskok staff members have been preparing the soil for future planting and harvesting. Moore has been working on a 1-acre welcome garden that includes #perennials, #FruitTrees, #SweetGrass, #blueberries and other plants. Last week, she planted 70 #asparagus seedlings and 35 #rhubarb plants.

"Plans also are underway to spruce up a #farmstand where Niweskok will share #FreeProduce with neighbors.

"Moore has also been focused on working to restore the forests as #FoodForests — a process that will take years — and has started selective cutting to support existing #hazelnut groves and #BlackCherries.

"Niweskok will also create outdoor classrooms for community members to engage with the land, including demonstrations on plantings and #agroforestry techniques.

" 'An outdoor kitchen is one of our high-priority areas because so much of our time and how we want to support our community is being with our foods and outside as much as possible,' Moore said. 'Cooking over open fire is not only a way we want to engage with folks, but an important, culturally significant and really beautiful way to be together.'

"Niweskok this month was awarded the #EspyHeritageAward from the #MaineCoastHeritageTrust, an annual award that recognizes those who make outstanding contributions to #LandConservation while inspiring others. It was the first time the award was given to an #Indigenous-led group.

"Angela Twitchell, director of partnerships and public policy for Maine Coast Heritage Trust, said Niweskok’s work to restore the Penobscot Bay region as a Wabanaki food hub is 'an inspiring example of how land conservation is evolving.'

"For decades starting in the 1950s, land conservation was centered on ecological and species protection and protecting lands from people and development. It has since evolved to center its work in community, Twitchell said.

" '(Niweskok’s) work embodies resilience and a deep commitment to healing and nourishing both the land and the community,' she said. 'The collaborative work between #LandTrusts and Niweskok stands as a model to be replicated.'

"Moore said the award acknowledges the leadership of Niweskok, and added that other incredible Wabanaki-led land work is happening in the region. Moore hopes the award indicates that Maine conservation groups will continue to find ways to support Wabanaki leadership in conservation.

"Having the land has been a 'beautiful invitation' for the #NonWabanaki community 'to support Wabanaki food sovereignty and be in support of our leadership in care of the land,' Moore said."

Source:
https://www.pressherald.com/2025/05/08/wabanaki-group-restoring-245-acre-farm-in-swanville-as-food-hub/

Archived version:
https://archive.md/Ii0au

#WabanakiConfederacy
#MaineFirstNations #LandBack #FoodSecurity #FoodSovereignty #sovereignty #Wabanakik #WabanakiAlliance #Decolonize #SolarPunkSunday #LandStewards #stewardship #NatureEducation #Foraging #Maine #IndigenousPeoplesDay

🧶 …

In pharmacology, an #antidepressant refers to a fairly diverse set of molecules that do not have the same modes of action, the same therapeutic effects or the same undesirable effects.

A common goal: to target monoamines, neuromodulators

Generally speaking, these are molecules that target what are called #neurotransmitters, including serotonin, noradrenaline or dopamine. When a neurotransmitter attaches to receptors in one neuron, it transmits an electrical message that can be transmitted to another neuron. It's kind of like a relay race. There are over 20 different types of synapses, each of which conveys specific messages and are involved in this brain activity differently."

…

#cognition #SilentSunday #wellness #medicine #antidepressants #health #medicines #science #psychology #neurosciences #brain #suicidal #suicide #depression #mood #confidence #bias #beliefs #selfDepreciation #mentalHealth

How to #decolonize your #Thanksgiving dinner in observance of #NationalDayofMourning

Meredith Clark
Wed, November 22, 2023

"Thanksgiving is almost upon us, a time when many #Americans gather together to eat turkey and talk about what they’re most thankful for. Growing up in the #UnitedStates, almost everyone can recall the 'First Thanksgiving' story they were told in elementary school: how the local #Wampanoag #NativeAmericans sat down with the #pilgrims of #Plymouth Colony in 1621, in what is now present-day #Massachusetts, for a celebratory feast.

"However, this story is far from the truth - which is why many people opt out of celebrating the controversial holiday.

"For many #Indigenous communities throughout the US, Thanksgiving remains a National Day of Mourning - a reminder of the devastating #genocide and #displacement that occurred at the hands of European #colonisers following their arrival in the Americas.

"Every year since 1970, #IndigenousPeople and their allies have even gathered near #PlymouthRock to commemorate a National #DayOfMourning on the day of Thanksgiving. 'Thanksgiving Day is a reminder of the genocide of millions of Native people, the theft of Native lands, and the erasure of Native cultures,' states the official website for the United American Indians of New England. 'Participants in National Day of Mourning honour Indigenous #ancestors and Native resilience. It is a day of #remembrance and #spiritual connection, as well as a #protest against the #racism and #oppression that Indigenous people continue to experience #worldwide.'

"This year, the 54th annual National Day of Mourning takes place on 23 November - the same day as Thanksgiving. While not everyone can support the event in person, there are still many ways people can raise awareness toward issues affecting Indigenous communities from wherever they are - by '#decolonising' their Thanksgiving dinner.

"#Decolonisation can be defined as the active resistance against #settlerColonialism and a shifting of power towards Indigenous sovereignty. Of course, it’s difficult to define decolonisation without putting it into practice, writes Eve Tuck and K Wayne Yang in their essay, #Decolonization Is Not a Metaphor. Rather, one of the most radical and necessary moves toward decolonisation requires imagining and enacting a future for Indigenous peoples - a future based on terms of their own making.

"Matt Hooley is an assistant professor in the department of Native American and Indigenous Studies at Dartmouth College, where he teaches about US colonial powers and Indigenous cultural production. 'Decolonisation is a beautiful and difficult political horizon that should guide our actions everyday, including during holidays like Thanksgiving,' he tells The Independent. 'Of course, Thanksgiving is a particularly relevant holiday to think about decolonisation because the way many people celebrate it involves connecting ‘the family’ to a colonial myth in which colonialism is inaccurately imagined as a peaceful event in the past.'

"By decolonising our Thanksgiving, we can celebrate the holiday with new traditions that honour a future in which Indigenous people are celebrated. This year, we can start by understanding the real history behind Thanksgiving as told by actual Indigenous communities.

"While Americans mainly dedicate one day a year to give thanks, Indigenous communities express gratitude every day with the #Haudenosaunee Thanksgiving Address - often called: 'The words that come before all else.' The Haudenosaunee Thanksgiving Address is the central prayer and invocation for the #HaudenosauneeConfederacy, which comprises the #SixNations - #Mohawk, #Oneida, #Onondaga, #Cayuga, #Seneca, and #Tuscarora. When one recites the Thanksgiving Address, they’re giving thanks for all life and the natural world around them.

"According to Hooley, one of the most straightforward actions people can take to decolonise their Thanksgiving includes supporting Indigenous land acknowledgments and land back movements. #LandBack is an ongoing Indigenous-led movement which seeks to return ancestral lands to Indigenous people and the recognition of Indigenous #sovereignty. While the movement is nowhere near new, it received international attention in 2016 during protests against the #DakotaAccesSPipeline - which continues to disrupt land and #water sources belonging to the #StandingRockSioux Tribe.

"This year, sit down with family and friends to discuss an action plan and highlight the concrete steps you plan on taking to support Indigenous communities. 'Another, even simpler way would be to begin participating in what’s called a ‘Voluntary Land Tax,’ whereby non-Indigenous people contribute a recurring tax to the tribal communities whose land you occupy,' said Hooley.

"Food is perhaps the most important part of the Thanksgiving holiday, with turkey, stuffing, and mashed potatoes taking center stage. However, there are many ways we can make sure our dinner tables honour Indigenous futurisms too. Donald A Grinde, Jr is a professor emeritus in the department of Africana and American Studies at the University at Buffalo. Grinde - who is a member of the #YamasseeNation - tells The Independent that crops such as #corn, #beans, #squash, #tomatoes, and #potatoes are central to #IndigenousHistory and future.

"'A good thing is to be thankful for the abundance in the fall and note that Native people created over 60 percent of modern #agricultural #crops,' he said. 'People can be thankful for the crops that Native people created, #medicines created, and traditions about #democracy, #WomensRights and #environmental rights.'

"Rather than buying food from major corporations this year, Hooly also recommended people consciously source their Thanksgiving dinner from Indigenous producers. 'Industrial agriculture is one of the most devastating contributors to the destruction of land and water everywhere, including on Indigenous land,' he said. 'Instead of buying food grown or made by colonial corporations, people could buy their food from Indigenous producers, or even simply make a greater effort to buy locally grown food or not to buy meat harvested from industrial farms.'

"Thanksgiving is just a day away. While it’s important that we’re actively working toward highlighting Indigenous communities on this special holiday, decolonisation efforts are something that should be done year-round.

"'People can also learn about political priorities of the Indigenous communities near them and support those priorities by speaking to their representatives, participating in a protest, or by making sure that their local school and library boards are including Indigenous texts in local community education,' Hooley said."

https://www.yahoo.com/lifestyle/decolonize-thanksgiving-dinner-observance-national-213225020.html

#Decolonization #CorporateColonialism #LandTheft #CulturalGenocide #CulturalPreservation

Dwindling tropical rainforests mean lost medicines yet to be discovered in their plants

About 80% of the world population relies on compounds derived from plants for medicines to treat various ailments, such as malaria and cancer, and to suppress pain. Our future medicines are likely to come from plants, but how effectively are we protecting these plants from extinction? We aren’t doing enough and we must do more!

#Medicine 💊 humans need for our future survival will likely come from #rainforests 🍃🌳 Yet we aren’t stopping #deforestation! Help forests and forest animals! Be #vegan 🥦🍆🥑 and #Boycottpalmoil #Boycott4Wildlife 🌴🪔☠️🔥🧐⛔️ @palmoildetect https://palmoildetectives.com/2023/04/23/dwindling-tropical-rainforests-mean-lost-medicines-yet-to-be-discovered-in-their-plants/

80% of the world’s population relies on #medicines 💊from #rainforests. As greedy companies destroy #Borneo, the #Congo and the #Amazon, the world edges ever closer to losing medicines forever! #Boycottpalmoil 🌴💀🚫 #Boycott4Wildlife @palmoildetect https://palmoildetectives.com/2023/04/23/dwindling-tropical-rainforests-mean-lost-medicines-yet-to-be-discovered-in-their-plants/

Written by Walter Suza, Adjunct Assistant Professor of Agronomy, Iowa State University. This article is republished from The Conversation under a Creative Commons license. Read the original article.

Walter Suza, Iowa State University

As fires continue to burn in the Amazon and land is cleared for agriculture, most of the concerns have focused on the drop in global oxygen production if swaths of the forests disappear. But I’m also worried about the loss of potential medicines that are plentiful in forests and have not yet been discovered. Plants and humans also share many genes, so it may be possible to test various medicines in plants, providing a new strategy for drug testing.

As a plant physiologist, I am interested in plant biodiversity because of the potential to develop more resilient and nutritious crops. I am also interested in plant biodiversity because of its contribution to human health. About 80% of the world population relies on compounds derived from plants for medicines to treat various ailments, such as malaria and cancer, and to suppress pain.

Future medicines may come from plants

One of the greatest challenges in fighting diseases is the emergence of drug resistance that renders treatment ineffective. Physicians have observed drug resistance in the fight against malaria, cancer, tuberculosis and fungal infections. It is likely that drug resistance will emerge with other diseases, forcing researchers to find new medicines.

Plants are a rich source of new and diverse compounds that may prove to have medicinal properties or serve as building blocks for new drugs. And, as tropical rainforests are the largest reservoir of diverse species of plants, preserving biodiversity in tropical forests is important to ensure the supply of medicines of the future.

Plants and new cholesterol-lowering medicines

The goal of my own research is to understand how plants control the production of biochemical compounds called sterols. Humans produce one sterol, called cholesterol, which has functions including formation of testosterone and progesterone – hormones essential for normal body function. By contrast, plants produce a diverse array of sterols, including sitosterol, stigmasterol, campesterol, and cholesterol. These sterols are used for plant growth and defense against stress but also serve as precursors to medicinal compounds such as those found in the Indian Ayurvedic medicinal plant, ashwagandha.

Humans produce cholesterol through a string of genes, and some of these genes produce proteins that are the target of medicines for treating high cholesterol. Plants also use this collection of genes to make their sterols. In fact, the sterol production systems in plants and humans are so similar that medicines used to treat high cholesterol in people also block sterol production in plant cells.

I am fascinated by the similarities between how humans and plants manufacture sterols, because identifying new medicines that block sterol production in plants might lead to medicines to treat high cholesterol in humans.

New medicines for chronic and pandemic diseases

An example of a gene with medical implications that is present in both plants and humans is NPC1, which controls the transport of cholesterol. However, the protein made by the NPC1 gene is also the doorway through which the Ebola virus infects cells. Since plants contain NPC1 genes, they represent potential systems for developing and testing new medicines to block Ebola.

This will involve identifying new chemical compounds that interfere with plant NPC1. This can be done by extracting chemical compounds from plants and testing whether they can effectively prevent the Ebola virus from infecting cells.

There are many conditions that might benefit from plant research, including high cholesterol, cancer and even infectious diseases such as Ebola, all of which have significant global impact. To treat high cholesterol, medicines called statins are used. Statins may also help to fight cancer. However, not all patients tolerate statins, which means that alternative therapies must be developed.

Tropical rainforests are medicine reservoirs

The need for new medicines to combat heart disease and cancer is dire. A rich and diverse source of chemicals can be found in natural plant products. With knowledge of genes and enzymes that make medicinal compounds in native plant species, scientists can apply genetic engineering approaches to increase their production in a sustainable manner.

Tropical rainforests house vast biodiversity of plants, but this diversity faces significant threat from human activity.

To help students in my genetics and biotechnology class appreciate the value of plants in medical research, I refer to findings from my research on plant sterols. My goal is to help them recognize that many cellular processes are similar between plants and humans. My hope is that, by learning that plants and animals share similar genes and metabolic pathways with health implications, my students will value plants as a source of medicines and become advocates for preservation of plant biodiversity.

Walter Suza, Adjunct Assistant Professor of Agronomy, Iowa State University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Written by Walter Suza, Adjunct Assistant Professor of Agronomy, Iowa State University. This article is republished from The Conversation under a Creative Commons license. Read the original article.

ENDS

Read more about RSPO greenwashing

Big brands using “sustainable” RSPO palm oil yet still causing deforestation (there are many others)

Nestlé

Nestlé is destroying rainforests, releasing mega-tonnes of carbon into the atmosphere, and killing hundreds of endangered species. Once these animals are gone – they are gone for good. See Nestlé’s full list of…

Colgate-Palmolive

Despite global retail giant Colgate-Palmolive forming a coalition with other brands in 2020, virtue-signalling that they will stop all deforestation, they continue to do this – destroying rainforest and releasing mega-tonnes of carbon…

Mondelēz

Mondelez destroys rainforests, sending animals extinct and release mega-tonnes of carbon into air for so-called “sustainable” palm oil. Boycott them!

Unilever

In 2020, global retail giant Unilever unveiled a deforestation-free supply chain promise. By 2023 they would be deforestation free. This has been and gone and they are still causing deforestation. This brand has…

Danone

Savvy consumers have been pressuring French Dairy multinational Danone for decades to cease using deforestation palm oil. Yet they actually haven’t stopped this. From their website: ‘Danone is committed to eliminating deforestation from…

PepsiCo

Despite decades of promises to end deforestation for palm oil PepsiCo (owner of crisp brands Frito-Lay, Cheetos and Doritos along with hundreds of other snack food brands) have continued sourcing palm oil that…

Procter & Gamble

Despite decades of promises to end deforestation for palm oil Procter & Gamble or (P&G as they are also known) have continued sourcing palm oil that causes ecocide, indigenous landgrabbing, and the habitat…

Kelloggs/Kellanova

In late 2023, Kelloggs became Kellanova for their US arm. Savvy consumers have been pressuring Kelloggs for decades to cease using deforestation palm oil. Yet they actually haven’t stopped this. From their website:…

Johnson & Johnson

Global mega-brand Johnson & Johnson have issued a position statement on palm oil in 2020. ‘At Johnson & Johnson, we are committed to doing our part to address the unsustainable rate of global…

PZ Cussons

PZ Cussons is a British-owned global retail giant. They own well-known supermarket brands in personal care, cleaning, household goods and toiletries categories, such as Imperial Leather, Morning Fresh, Carex, Radiant laundry powder and…

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Wildlife Artist Juanchi Pérez

Mel Lumby: Dedicated Devotee to Borneo’s Living Beings

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The World’s Most Loved Cup: A Social, Ethical & Environmental History of Coffee by Aviary Doert

How do we stop the world’s ecosystems from going into a death spiral? A #SteadyState Economy

3. Supermarket sleuthing: Next time you’re in the supermarket, take photos of products containing palm oil. Share these to social media along with the hashtags to call out the greenwashing and ecocide of the brands who use palm oil. You can also take photos of palm oil free products and congratulate brands when they go palm oil free.

https://twitter.com/CuriousApe4/status/1526136783557529600?s=20

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https://twitter.com/mugabe139/status/1678027567977078784?s=20

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