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746 results for “cdk”
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[アップデート] AWS CDK で AppSync の GraphQL API に ownerContact を簡単に設定可能になりました
https://dev.classmethod.jp/articles/aws-cdk-appsync-graphql-api-owner-contact/ -
[アップデート] AWS CDK のアルファモジュールで AWS IoT Device Defender の「デバイス証明書の発行からの経過期間」のチェックが設定可能になりました
https://dev.classmethod.jp/articles/aws-cdk-alpha-aws-iot-device-defender-device-certificate-age-check/ -
Say Goodbye to Your CDK Stacks: A Guide to Self-Destruction
on @hashnodeQuick post on how to make CDK Stacks destroy themselves 🤯🧨💥
#aws #awscdk #serverless #automation #stepfunction https://matt.martz.codes/say-goodbye-to-your-cdk-stacks-a-guide-to-self-destruction
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Say Goodbye to Your CDK Stacks: A Guide to Self-Destruction
on @hashnodeQuick post on how to make CDK Stacks destroy themselves 🤯🧨💥
#aws #awscdk #serverless #automation #stepfunction https://matt.martz.codes/say-goodbye-to-your-cdk-stacks-a-guide-to-self-destruction
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Say Goodbye to Your CDK Stacks: A Guide to Self-Destruction
on @hashnodeQuick post on how to make CDK Stacks destroy themselves 🤯🧨💥
#aws #awscdk #serverless #automation #stepfunction https://matt.martz.codes/say-goodbye-to-your-cdk-stacks-a-guide-to-self-destruction
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AutoNation Says CDK Global Ransomware Attack Impacted Earnings https://www.securityweek.com/autonation-says-cdk-global-ransomware-attack-impacted-earnings/ #IncidentResponse #ransomware #CDKGlobal
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AutoNation Says CDK Global Ransomware Attack Impacted Earnings https://www.securityweek.com/autonation-says-cdk-global-ransomware-attack-impacted-earnings/ #IncidentResponse #ransomware #CDKGlobal
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AutoNation Says CDK Global Ransomware Attack Impacted Earnings https://www.securityweek.com/autonation-says-cdk-global-ransomware-attack-impacted-earnings/ #IncidentResponse #ransomware #CDKGlobal
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AutoNation Says CDK Global Ransomware Attack Impacted Earnings https://www.securityweek.com/autonation-says-cdk-global-ransomware-attack-impacted-earnings/ #IncidentResponse #ransomware #CDKGlobal
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GitHub Actions × AWS CDK で、OpenAPI 仕様書を Pull Request ごとに Web 上でプレビュー可能にするワークフローを組んでみた
https://dev.classmethod.jp/articles/github-actions-aws-cdk-preview-api-docs/#dev_classmethod #OpenAPI #Swagger #AWS_CDK #GitHub_Actions #Amazon_CloudFront #Amazon_S3
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Bedrock AgentCore RuntimeはCDKでらくらくデプロイ！コンテナいらずでHot swapも可能！！
https://qiita.com/moritalous/items/d865fc92921a822c1f44?utm_campaign=popular_items&utm_medium=feed&utm_source=popular_items -
Bedrock AgentCore RuntimeはCDKでらくらくデプロイ！コンテナいらずでHot swapも可能！！
https://qiita.com/moritalous/items/d865fc92921a822c1f44?utm_campaign=popular_items&utm_medium=feed&utm_source=popular_items -
Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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How Mitochondrial Dynamism Orchestrates Mitophagy
Authors Orian S. Shirihai, Moshi Song, Gerald W. Dorn II
Understanding the Significance of Mitochondrial Fission and Fusion
Mitochondrial dynamics refers to the movement of #mitochondria within a cell. This includes #fission, which is when mitochondria divide into two parts, #fusion, which is when two mitochondria join together, and #translocation, which is when mitochondria move from one part of the #cell to another. This movement is important for maintaining the stability of the mitochondrial #DNA, which is the genetic material found in mitochondria, and for controlling the cell's #respiration. It can also be involved in programmed #CellDeath. In the #heart, mitochondrial dynamics #protein s, such as #mitofusin s, optic #atrophy, and dynamin-related protein, are highly expressed and play an important role in maintaining the quality of the #mitochondria. Other roles for mitochondrial dynamics proteins in the #heart include helping to move #calcium into the mitochondria and regulating the structure of the mitochondria.
#Mitochondria are organelles in cells that are responsible for producing #energy. They can change their structure by breaking apart (#fission) and reforming (#fusion). This process is complicated and energy intensive, so it is important to understand why it is necessary. One reason may be that when cells divide, the mitochondria need to be divided equally between the two daughter cells. This requires the #mitochondria to be broken apart and then reformed in each daughter #cell. This process of breaking apart and reforming is more efficient than growing and budding the mitochondria. To help explain this process, the authors use the analogy of an army. Each soldier in the army is like a protein in the mitochondria, and the different units of the army are like the different parts of the #mitochondria. To increase the size of the army, units are added, rather than individual soldiers. This is similar to how mitochondria are modified, by adding or subtracting intact functional units, rather than individual #protein s.
Mitochondria are #organelle s in cells that can change their physical structure by undergoing fission. Fission can be symmetrical, which is when mitochondria replicate and expand the number of #mitochondria in the #cell, or asymmetrical, which is when damaged components of the mitochondria are removed. The major #protein that helps with mitochondrial fission is called Drp1. It is mostly found in the #cytosol, but it needs to be recruited to the outer mitochondrial #membrane to help with fission. Different factors can cause Drp1 to be recruited, such as phosphorylation by mitotic kinase cyclin B–cyclin-dependent-kinase (cdk) 1 complex during #cell division, or interacting with Bcl-2–associated protein x during #apoptosis. Inhibiting Drp1 can protect cells from some, but not all, forms of programmed cell death.
Mitochondria, which are organelles in cells, can be partitioned in #mitosis. The most efficient way to do this is by dismantling and then reconstituting the cellular #mitochondria network through sequential #organelle fission, distribution, and refusion. To explain this concept, the text uses an analogy of how military units are constituted and managed within an army's hierarchical organization structure. In this analogy, each soldier represents an individual respiratory complex #protein, which are grouped together to form a squad (analogous to a respiratory complex). Squads are arranged into platoons, and approximately 6 platoons comprise a functional unit, the company (like 1 complete respiratory chain). The text suggests that it would be easier to add prefabricated supercomplexes to preexisting ones, as by fusing mitochondrial cristae, rather than trying to make a larger or different shaped mitochondrion through the wholesale incorporation of individual proteins. This is because making major structural modifications of respiratory supercomplexes on paracrystalline cristal membranes would first require destabilizing the #membrane, then incorporating additional individual #protein components, and finally reconstructing the original highly organized structure, which is complicated and potentially disruptive.
#Mitochondria are small organelles in cells that can change their physical structure by undergoing fission. Fission can be symmetrical, which means the #mitochondria are split into two equal parts, or asymmetrical, which means the mitochondria are split into two unequal parts. Symmetrical fission is used to replicate and expand the number of mitochondria in the #cell, while asymmetrical fission is used to remove damaged mitochondria from the cell. The major #protein responsible for mitochondrial fission is called Drp1. Drp1 is mostly found in the cytosol, but it needs to be recruited to the outer mitochondrial #membrane to promote fission. Different factors can stimulate Drp1 to move to the outer mitochondrial #membrane, such as phosphorylation by mitotic kinase cyclin B–cyclin-dependent-kinase (cdk) 1 complex. In addition, the endoplasmic reticulum (ER) is often found at the sites of mitochondrial fission. If Drp1 is not present, the mitochondria can still fragment during #mitosis, suggesting that there are other mechanisms that can promote mitochondrial fission.
The text is talking about the process of mitochondrial fission, which is a process that involves connecting and separating parts of a #mitochondria. The author uses the metaphor of making sausage links to explain the process, but then goes on to explain that mitochondria are actually more like a turducken, which is a dish made of a chicken stuffed inside a duck stuffed inside a turkey. This creates layers of poultry, which is similar to the double #membrane /double space structure of #mitochondria. The author then explains that the process of mitochondrial fusion involves connecting the two mitochondria layer by layer, using proteins called mitofusins. Mitofusins have a #GTPase domain, two hydrophobic heptad repeat coiled-coil domains, and a small hydrophobic transmembrane domain. These proteins insert into the outer #membrane of the #mitochondria, and can interact with other proteins in the cytosol. The process of mitochondrial fusion is GTP-independent and reversible, but #GTP #hydrolysis is essential for irreversible outer membrane fusion.
#Mitofusins are proteins that are essential for the first two stages of mitochondrial fusion, which is the process of two mitochondria joining together. This process is important for the exchange of information between the #mitochondria and the #cell. If the mitofusins are deleted or suppressed, the mitochondria become abnormally small and are unable to undergo normal fusion. This can have serious implications for the health of the #cell.
Membrane-by-membrane mitochondrial fusion is a process that helps to keep the structure of the inner and outer membranes of #mitochondria intact. This helps to preserve the process of oxidative phosphorylation, which is important for providing energy to cells. Without this process, molecules that can be toxic to cells can form and interrupt the electron transport chain. This process is also important for maintaining the normal shape of the crista, which is necessary for the proper assembly and functioning of electron transport chain supercomplexes. In addition, it has been shown that interrupting Mfn-mediated OMM fusion can cause a #cardiomyocyte ER stress response, while interrupting Opa1-mediated IMM fusion can compromise mitochondrial function.
Mitochondrial fission and fusion are important processes in #biology, as evidenced by the fact that mutations in genes related to these processes can cause serious diseases in humans. Altering the balance between fission and fusion can have an effect on the shape of #mitochondria, with more fusion leading to longer, more interconnected mitochondria, and more fission leading to shorter, less interconnected mitochondria. It is generally thought that more interconnected #mitochondria are healthier, but this is not always the case. In some cases, mitochondrial #fragmentation can be beneficial, and it is important to understand the interplay between mitochondrial fragmentation and other processes, such as #mitophagy, in order to understand the effects of mitochondrial fission and fusion.
Mitophagy is a process by which cells eat their own #mitochondria. Mitochondria are organelles that produce energy in the form of #ATP, which is used to power most biological processes. Over time, mitochondria can become damaged and produce toxic levels of reactive oxygen species ( #ROS ). To protect the #cell from this damage, it has developed a sophisticated system to identify and remove these dysfunctional #mitochondria. This process is called mitophagy. #Mitophagy is a combination of the words mitochondria and #autophagy, which means "self-eating". It is a way for cells to selectively target and remove damaged mitochondria, while still keeping healthy ones. This helps to maintain the balance between having enough energy-producing #mitochondria and getting rid of the ones that are no longer functioning properly.
Pulse chase experiments are a type of scientific experiment used to study the behavior of molecules over time. In this particular experiment, researchers found that when #mitochondria (the energy-producing organelles in cells) are targeted for #mitophagy (a process of removing damaged mitochondria from the cell), they have a relatively depolarized #membrane potential before being removed. This means that the #mitochondria have a lower electrical charge than normal, and they are less likely to be involved in #fusion events (when two mitochondria join together). The time between the mitochondria becoming depolarized and being removed from the cell can range from less than an hour to about three hours, suggesting that there is a population of preautophagic #mitochondria (mitochondria that are about to be removed). This #preautophagic pool helps to explain the variation in mitochondrial #membrane potential in different cell types. The process that feeds mitochondria into the preautophagic pool is important for determining how quickly #mitochondria are removed from the #cell. Scientists have developed a technology to label individual mitochondria and track their #membrane potential, which has allowed them to identify the event at which depolarized #mitochondria are produced. This event is called asymmetrical fission, and it occurs when the daughter mitochondria produced by the fission event have different #membrane potentials - one daughter has a higher membrane potential than the mother mitochondrion, while the other daughter has a lower membrane potential. This process of asymmetrical fission helps to separate damaged components from healthy components before they are removed from the #cell.
The concept of mitochondrial fission and fusion and how it affects mitochondrial quality. It suggests that when the fusion factors Mfn1 and Mfn2 are both absent, unusually small and degenerated #mitochondria accumulate in adult mouse hearts. This was associated with impaired #cardiomyocyte respiration, but not with measurable alterations in #oxygen consumption. It was later discovered that the isolation procedure used was not capturing the fragmented #mitochondria produced by interrupting mitochondrial fusion. This led to the discovery that Mfn2 is essential to #Parkin-mediated #mitophagy, which is a process that helps to maintain mitochondrial quality. Three recent papers have also implicated the mitochondrial fission protein Drp1 in cardiac #mitophagy, and it is suggested that if asymmetrical mitochondrial fission normally precedes mitophagy, then chronic suppression of fission by ablating Drp1 would have different consequences on #mitophagy depending on when it is assayed.
Mfn2 and PINK1–Parkin Mitophagy Signaling is a mechanism for controlling the quality of #mitochondria in the body. #PINK1 and #Parkin are proteins that are linked to #Parkinson's disease, and mutations in their genes were the first to be identified as causing the disease. Scientists have studied how PINK1 interacts with Parkin, and how this interaction can lead to the destruction of damaged #mitochondria, which is called #mitophagy. #PINK1 is like an ignition switch that senses when mitochondrial damage has occurred, and then activates Parkin-mediated mitophagy. PINK1 is normally not present in healthy #mitochondria, but when mitochondrial damage occurs, PINK1 accumulates and triggers the destruction of the damaged #mitochondria.
PINK1 is a protein that accumulates on damaged mitochondria and helps to promote mitophagy, which is the process of getting rid of damaged mitochondria. PINK1 does this by inducing the cytosolic protein Parkin to move to the mitochondria and ubiquitinate proteins on the outer membrane of the mitochondria. This helps to prevent the spread of damage from the damaged mitochondria to the healthy ones. PINK1 also inhibits the fusion of the damaged mitochondria. There are different theories about the biochemical events that cause Parkin to move to the mitochondria and stop the fusion. It is thought that PINK1 phosphorylates Parkin on certain sites, which helps Parkin bind to the mitochondria. It is also thought that PINK1 phosphorylates ubiquitin, which helps Parkin bind to the mitochondria and ubiquitinate proteins on the outer membrane. Finally, it is thought that PINK1 phosphorylates Mfn2, which helps Parkin bind to the mitochondria and ubiquitinate proteins on the outer membrane. All of these processes help to promote mitophagy and prevent the spread of damage from the damaged mitochondria to the healthy ones.
#PINK1 is a protein that plays an important role in a process called #mitophagy, which is a form of quality control for mitochondria. Mutations in the #PINK1 #gene have been linked to hereditary #Parkinson's disease in humans, but when the PINK1 gene is deleted in mice, it does not cause the same #neurodegenerative pattern seen in humans. Even when the genes for PINK1, Parkin, and DJ-1 are all deleted in mice, it still does not cause the same loss of dopaminergic #neuron s seen in #Parkinson's disease patients. This suggests that there may be other pathways that can compensate for the loss of #PINK1 and #Parkin, such as increased transcription of other E3 #ubiquitin ligases in the hearts of Parkin-knockout mice.
The text is discussing the idea of mitochondrial quality control pathways, which are processes that help keep mitochondria healthy. The text is suggesting that there may be alternate pathways that can be used to maintain mitochondrial health, rather than waiting until the mitochondria are completely depolarized before triggering their removal. It is comparing this idea to the idea of maintaining a car, where it is better to perform regular maintenance and repairs rather than waiting until the car is completely broken down before replacing it.
Like a car, mitochondria can be maintained through preventative maintenance, such as replacing worn parts, and that more serious damage can be repaired by removing and replacing individual components. It also suggests that, like a car, #mitochondria can be repaired by removing and replacing damaged parts, but on a smaller scale. The different types of maintenance and repair may be part of a continuum, rather than distinct categories.
#Mitophagy and mitochondrial dynamism are two processes that are closely connected. Mitophagy is the process of removing damaged #mitochondria from the #cell, while mitochondrial dynamism is the process of mitochondria fusing together and separating. The two processes work together to keep the cell healthy by eliminating damaged mitochondria and preventing healthy mitochondria from being contaminated by the damaged ones. The protein #Mfn2 plays a role in both processes, acting as a factor for mitochondrial fusion when it is not acted on by #PINK1 and as a receptor for #Parkin when it is. This suggests that the two processes are mutually exclusive, meaning that they cannot happen at the same time. This helps to protect healthy #mitochondria from being contaminated by the damaged ones. Finally, the involvement of PINK1 and Parkin in multiple mitochondrial quality control mechanisms shows that there are multiple ways to keep the #mitochondria healthy, which is important for preventing chronic degenerative diseases and providing opportunities for #therapeutic intervention.
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https://www.pulumi.com/blog/cdktf-is-deprecated-whats-next-for-your-team/ - Now that #Terraform CDKTF is deprecated, what's next? #Pulumi is right there, and #HCL was never bad anyway. Or ... Great discussion Adam Gordon Bell and Christian Nunciato.
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Choco Pro Road to Korakuen - Sakura Days show on March 13th at Shinkiba 1st RING!
TJPW's Mizuki will face Miyu Yotsuba
Also:
4 Way Asia Dream Tag Title match - Best Bros (c) vs Kung Fu Panda vs Obihiro Shokudo Sohonten vs Ninja Choke
CDK vs Munetatsu Nakamura & Gaia Hox
Emi Sakura & Makoto vs Sayaka & Eriko (new rookie)
#Joshi #JoshiWrestling #ChocoPro #wrestling #Puro #Japan #TJPW
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https://www.europesays.com/it/484085/ LIVE Alle 20.45 Milan-Atalanta, le ufficiali: Leao titolare, per Palladino Krstovic e l'ex CDK – La Gazzetta dello Sport #abbonamento #AbbonamentoZona #AbbonamentoZonaDazn #Calcio #dazn #Football #IT #Italia #Italy #Sky #Soccer #Sport #Sports
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- https://travailleur-alpin.fr/2026/01/12/grenoble-verite-et-justice-pour-les-six-victimes-kurdes-assassinees-a-paris/ (Grenoble. Vérité et justice pour les six victimes kurdes assassinées à Paris)
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# Le Rojava menacé
Puis les différentes organisations appelant au rassemblement ont évoqué l’avenir préoccupant pour la Syrie et la région : interventions armées de la Turquie et d’Israël, populations alaouite et druze victimes de massacres commis par l’Armée nationale syrienne (ANS) et une partie des forces gouvernementales, agressions de Daech, quartiers kurdes d’Alep bombardés par les forces militaires relevant du gouvernement de Damas…
Le Rojava (administration autonome du Nord et de l’Est de la Syrie) est menacé. Pourtant c’est un acquis démocratique précieux pour l’avenir de la Syrie. Après avoir combattu et vaincu l’État islamique en 2015, notamment à Kobané, les combattantes et combattants du Rojava ont en effet mis en place sur le territoire libéré une société démocratique, multiethnique, féministe, où les femmes et les hommes sont à parité à tous les niveaux (conseil municipal, administration, armée…), où toutes les personnes vivent à égalité de droits, quelle que soit leur appartenance culturelle, leur langue, leur religion.
L’expérience démocratique du Rojava (https://travailleur-alpin.fr/2018/03/12/mobilisation-a-grenoble-solidarite-populations-kurdes-rojava-turquie/) est sans pareille dans tout le Moyen-Orient.
Dans un communiqué, le CDK‑F (https://cdkf.fr/) indique que, depuis plusieurs jours, les quartiers kurdes de Sheikh Maqsoud et d’Achrafieh, à Alep (https://www.lemonde.fr/international/article/2026/01/12/a-alep-en-syrie-le-pouvoir-reprend-les-quartiers-kurdes_6661447_3210.html) , sont la cible d’attaques militaires intensifiées menées par les forces armées de Damas.
Déjà soumis à un blocus sévère, ces quartiers densément peuplés, majoritairement habités par des civils et des personnes déplacées, subissent désormais des bombardements lourds et indiscriminés.
Selon l’organisation, ces attaques s’inscrivent dans une logique de punition collective et de mise sous pression d’une population civile, au mépris total du droit international humanitaire.
# Appel à la France pour sauver les Kurdes d’Alep
Cette escalade intervient alors même que des discussions politiques sont en cours sur l’avenir de la Syrie et sur les modalités d’une solution durable et inclusive.
Face à cette situation, la France ne peut rester silencieuse.
En tant que membre permanent du Conseil de sécurité des Nations unies, puissance diplomatique majeure et acteur engagé dans la lutte contre le terrorisme en Syrie, la France a une responsabilité politique et morale particulière.
Le CDK‑F appelle les autorités françaises à condamner publiquement et sans ambiguïté les attaques visant les civils à Alep ; agir diplomatiquement pour obtenir l’arrêt immédiat des bombardements et la levée du blocus imposé aux quartiers concernés ;
soutenir l’ouverture de corridors humanitaires afin de permettre l’accès aux secours et aux soins ;
œuvrer activement, dans les enceintes internationales, à une solution politique fondée sur le dialogue, le respect des droits des peuples et la protection des populations civiles.
Le peuple syrien a trop souffert de la guerre.
Les civils kurdes d’Alep, comme l’ensemble des composantes du pays, ont droit à la sécurité, à la dignité et à la paix.
Le Conseil démocratique kurde en France restera mobilisé et appelle l’ensemble des forces démocratiques, humanitaires et politiques en France à se saisir de cette urgence.
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#AIAK #Grenoble #Solidarite #Kurdistan #Kurdes #Alep #Syrie #CDKF -
- https://aiak.frama.io/aiak-info/articles/2026/01/08/communique-syrie-les-civils-kurdes-d-alep-pris-pour-cible-la-france-doit-agir.html (Syrie : les civils kurdes d’Alep pris pour cible, la France doit agir)
Article au format PDF: https://aiak.frama.io/aiak-info/_downloads/94caedbdbd89d70485a9c04b407d0781/communique-syrie-les-civils-kurdes-d-alep-pris-pour-cible-la-france-doit-agir-2026_01_08.pdf
Conseil Démocratique Kurde en France Syrie : les civils kurdes d’Alep pris pour cible, la France doit agir Depuis plusieurs jours, les quartiers kurdes de Sheikh Maqsoud et d’Achrafieh, à Alep, sont la cible d’attaques militaires intensifiées menées par les forces relevant du gouvernement de Damas.
Déjà soumis à un blocus sévère, ces quartiers densément peuplés, majoritairement habités par des civils et des personnes déplacées, subissent désormais des bombardements lourds et indiscriminés.
Selon des informations documentées, au moins neuf civils ont été tués et des dizaines de personnes, dont de nombreux enfants, ont été blessées au cours des dernières attaques.
Des armes lourdes, de l’artillerie, des roquettes ainsi que des drones kamikaze ont été utilisés contre des zones civiles, provoquant une situation humanitaire alarmante.
L’accès aux soins, à l’eau, à l’électricité et aux biens de première nécessité est gravement compromis.
Le Conseil démocratique kurde en France alerte sur le fait que ces attaques s’inscrivent dans une logique de punition collective et de mise sous pression d’une population civile, au mépris total du droit international humanitaire.
Les habitants kurdes de ces quartiers, présents à Alep depuis des générations, sont aujourd’hui exposés à un risque majeur de nouvelle catastrophe humanitaire.
Cette escalade intervient alors même que des discussions politiques sont en cours sur l’avenir de la Syrie et sur les modalités d’une solution durable et inclusive.
L’usage de la force contre des civils ne peut en aucun cas constituer une réponse politique.
Il ne fera qu’aggraver les tensions et éloigner toute perspective de paix.
Face à cette situation, la France ne peut rester silencieuse.En tant que membre permanent du Conseil de sécurité des Nations unies, puissance diplomatique majeure et acteur engagé dans la lutte contre le terrorisme en Syrie, la France a une responsabilité politique et morale particulière.
Le CDK-F appelle les autorités françaises à :
- condamner publiquement et sans ambiguïté les attaques visant les civils à Alep ;
- agir diplomatiquement pour obtenir l’arrêt immédiat des bombardements et la levée du blocus imposé aux quartiers concernés ;
-soutenir l’ouverture de corridors humanitaires afin de permettre l’accès aux secours et aux soins ;
- œuvrer activement, dans les enceintes internationales, à une solution politique fondée sur le dialogue, le respect des droits des peuples et la protection des populations civiles.
Le peuple syrien a trop souffert de la guerre.
Les civils kurdes d’Alep, comme l’ensemble des composantes du pays, ont droit à la sécurité, à la dignité et à la paix.
Le Conseil démocratique kurde en France restera mobilisé et appelle l’ensemble des forces démocratiques, humanitaires et politiques en France à se saisir de cette urgence.
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16 rue d’Enghien, 75010 Paris -
[email protected] - www.cdkf.fr -
Tel: 01 83 91 06 43 - @Le_CDKF-->--
Depuis plusieurs jours, les quartiers kurdes de Sheikh Maqsoud et d’Achrafieh, à Alep, sont la cible d’attaques militaires intensifiées menées par les forces relevant du gouvernement de Damas.vous trouverez ci dessus la déclaration du CD KF.
A ce soir jeudi 8 janvier 2026 au rassemblement de #Grenoble (https://aiak.frama.io/aiak-info/_downloads/18d237b4f575ac5318fdce814340bf5e/appel_pour_le_8_janvier_2026.pdf)
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- https://aiak.frama.io/aiak-info/articles/2026/01/08/communique-syrie-les-civils-kurdes-d-alep-pris-pour-cible-la-france-doit-agir.html (Syrie : les civils kurdes d’Alep pris pour cible, la France doit agir)
Article au format PDF: https://aiak.frama.io/aiak-info/_downloads/94caedbdbd89d70485a9c04b407d0781/communique-syrie-les-civils-kurdes-d-alep-pris-pour-cible-la-france-doit-agir-2026_01_08.pdf
Conseil Démocratique Kurde en France Syrie : les civils kurdes d’Alep pris pour cible, la France doit agir Depuis plusieurs jours, les quartiers kurdes de Sheikh Maqsoud et d’Achrafieh, à Alep, sont la cible d’attaques militaires intensifiées menées par les forces relevant du gouvernement de Damas.
Déjà soumis à un blocus sévère, ces quartiers densément peuplés, majoritairement habités par des civils et des personnes déplacées, subissent désormais des bombardements lourds et indiscriminés.
Selon des informations documentées, au moins neuf civils ont été tués et des dizaines de personnes, dont de nombreux enfants, ont été blessées au cours des dernières attaques.
Des armes lourdes, de l’artillerie, des roquettes ainsi que des drones kamikaze ont été utilisés contre des zones civiles, provoquant une situation humanitaire alarmante.
L’accès aux soins, à l’eau, à l’électricité et aux biens de première nécessité est gravement compromis.
Le Conseil démocratique kurde en France alerte sur le fait que ces attaques s’inscrivent dans une logique de punition collective et de mise sous pression d’une population civile, au mépris total du droit international humanitaire.
Les habitants kurdes de ces quartiers, présents à Alep depuis des générations, sont aujourd’hui exposés à un risque majeur de nouvelle catastrophe humanitaire.
Cette escalade intervient alors même que des discussions politiques sont en cours sur l’avenir de la Syrie et sur les modalités d’une solution durable et inclusive.
L’usage de la force contre des civils ne peut en aucun cas constituer une réponse politique.
Il ne fera qu’aggraver les tensions et éloigner toute perspective de paix.
Face à cette situation, la France ne peut rester silencieuse.En tant que membre permanent du Conseil de sécurité des Nations unies, puissance diplomatique majeure et acteur engagé dans la lutte contre le terrorisme en Syrie, la France a une responsabilité politique et morale particulière.
Le CDK-F appelle les autorités françaises à :
- condamner publiquement et sans ambiguïté les attaques visant les civils à Alep ;
- agir diplomatiquement pour obtenir l’arrêt immédiat des bombardements et la levée du blocus imposé aux quartiers concernés ;
-soutenir l’ouverture de corridors humanitaires afin de permettre l’accès aux secours et aux soins ;
- œuvrer activement, dans les enceintes internationales, à une solution politique fondée sur le dialogue, le respect des droits des peuples et la protection des populations civiles.
Le peuple syrien a trop souffert de la guerre.
Les civils kurdes d’Alep, comme l’ensemble des composantes du pays, ont droit à la sécurité, à la dignité et à la paix.
Le Conseil démocratique kurde en France restera mobilisé et appelle l’ensemble des forces démocratiques, humanitaires et politiques en France à se saisir de cette urgence.
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16 rue d’Enghien, 75010 Paris -
[email protected] - www.cdkf.fr -
Tel: 01 83 91 06 43 - @Le_CDKF-->--
Depuis plusieurs jours, les quartiers kurdes de Sheikh Maqsoud et d’Achrafieh, à Alep, sont la cible d’attaques militaires intensifiées menées par les forces relevant du gouvernement de Damas.vous trouverez ci dessus la déclaration du CD KF.
A ce soir jeudi 8 janvier 2026 au rassemblement de #Grenoble (https://aiak.frama.io/aiak-info/_downloads/18d237b4f575ac5318fdce814340bf5e/appel_pour_le_8_janvier_2026.pdf)
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PhantomRaven Wave 5: New Undocumented NPM Supply Chain Campaign Targets DeFi, Cloud, and AI Developers
A fifth wave of the PhantomRaven NPM supply chain attack campaign has been discovered, utilizing 33 new malicious packages and fresh command-and-control infrastructure registered on March 10, 2026. The operation employs a sophisticated three-stage payload delivery mechanism using Remote Dynamic Dependency techniques to bypass static analysis. Malicious packages self-reference dependencies pointing to attacker-controlled servers at pack[.]nppacks[.]com, which deliver droppers that harvest developer credentials, system information, CI/CD tokens, GitHub repository names, and email addresses from Git configurations, NPM settings, and environment variables. The campaign specifically targets DeFi cryptocurrency developers, cloud infrastructure engineers working with Azure CDK, and AI application developers. All collected data is exfiltrated via POST requests to mozbra.php on the C2 server. Infrastructure analysis reveals connections to a legitimate Pakistani IT services company domain, suggesting potential accou...
Pulse ID: 69f8acdd6038448e350edbb9
Pulse Link: https://otx.alienvault.com/pulse/69f8acdd6038448e350edbb9
Pulse Author: AlienVault
Created: 2026-05-04 14:27:41Be advised, this data is unverified and should be considered preliminary. Always do further verification.
#Azure #Cloud #CyberSecurity #ELF #Email #GitHub #InfoSec #NPM #OTX #OpenThreatExchange #PHP #Pakistan #RAT #SupplyChain #Troll #bot #cryptocurrency #developers #AlienVault
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Nos camarades #kurdes encore frappés en plein Paris ! 3 morts dans l'attentat d'aujourd'hui, presque 10 ans après le triple assassinat de Fidan, Sakîne & Leyla. L'UCL est présente rue d'Enghien au rassemblement de solidarité avec le #ConseilDemocratiqueKurdeenFrance
Rassemblement de solidarité aussi demain midi, pl. de la République, à l'appel du #CDKF
RDV le 7 janvier à #Paris pour :
- la vérité sur les assassinats des 22/12/12 & 9/01/13
- la fin des bombardements d'#Erdogan sur le #Kurdistan -
Nos camarades #kurdes encore frappés en plein Paris ! 3 morts dans l'attentat d'aujourd'hui, presque 10 ans après le triple assassinat de Fidan, Sakîne & Leyla. L'UCL est présente rue d'Enghien au rassemblement de solidarité avec le #ConseilDemocratiqueKurdeenFrance
Rassemblement de solidarité aussi demain midi, pl. de la République, à l'appel du #CDKF
RDV le 7 janvier à #Paris pour :
- la vérité sur les assassinats des 22/12/12 & 9/01/13
- la fin des bombardements d'#Erdogan sur le #Kurdistan -
Nos camarades #kurdes encore frappés en plein Paris ! 3 morts dans l'attentat d'aujourd'hui, presque 10 ans après le triple assassinat de Fidan, Sakîne & Leyla. L'UCL est présente rue d'Enghien au rassemblement de solidarité avec le #ConseilDemocratiqueKurdeenFrance
Rassemblement de solidarité aussi demain midi, pl. de la République, à l'appel du #CDKF
RDV le 7 janvier à #Paris pour :
- la vérité sur les assassinats des 22/12/12 & 9/01/13
- la fin des bombardements d'#Erdogan sur le #Kurdistan -
Nos camarades #kurdes encore frappés en plein Paris ! 3 morts dans l'attentat d'aujourd'hui, presque 10 ans après le triple assassinat de Fidan, Sakîne & Leyla. L'UCL est présente rue d'Enghien au rassemblement de solidarité avec le #ConseilDemocratiqueKurdeenFrance
Rassemblement de solidarité aussi demain midi, pl. de la République, à l'appel du #CDKF
RDV le 7 janvier à #Paris pour :
- la vérité sur les assassinats des 22/12/12 & 9/01/13
- la fin des bombardements d'#Erdogan sur le #Kurdistan