#cohesin — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #cohesin, aggregated by home.social.
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Researchers uncover nuclear organization mechanism linked to Friedreich’s ataxia
Researchers have uncovered a fundamental rule that governs how genes are physically arranged inside the cell nucleus, and…
#Nuclear #Ataxia #Cell #CellNucleus #Cohesin #DNA #Friedreich'sAtaxia #Gene #GeneSilencing #genes #Genome #hospital #medicine #nuclear #Protein #research #transcription
https://www.europesays.com/2985368/ -
Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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Separase plays a key role in cleaving #cohesin complexes that hold #chromosomes together during cell division. Martin Anger explores a @PLOSBiology study showing that #separase activity is controled by #cyclin B/CDK1 & securin in #meiosis (and not SGO2). Paper: https://plos.io/3RAoccz Primer: https://plos.io/43L91UR
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🚨 Job alert 🚨
We're hiring a postdoc (computational or wet-lab) to work on genetic diseases of chromatin! 🧬
Come work with us at the Centre for Human Genetics in the beautiful University of Oxford
🗓️ Closing date September 13th 2024
Further details at beagrielab.com/join
Pls boost!
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🚨 Job alert 🚨
We're hiring a postdoc (computational or wet-lab) to work on genetic diseases of chromatin! 🧬
Come work with us at the Centre for Human Genetics in the beautiful University of Oxford
🗓️ Closing date September 13th 2024
Further details at beagrielab.com/join
Pls boost!
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🚨 Job alert 🚨
We're hiring a postdoc (computational or wet-lab) to work on genetic diseases of chromatin! 🧬
Come work with us at the Centre for Human Genetics in the beautiful University of Oxford
🗓️ Closing date September 13th 2024
Further details at beagrielab.com/join
Pls boost!
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🚨 Job alert 🚨
We're hiring a postdoc (computational or wet-lab) to work on genetic diseases of chromatin! 🧬
Come work with us at the Centre for Human Genetics in the beautiful University of Oxford
🗓️ Closing date September 13th 2024
Further details at beagrielab.com/join
Pls boost!
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#Centromere research yields new insights into the mechanisms of #chromosome #segregation errors.
https://phys.org/news/2024-05-centromere-yields-insights-mechanisms-chromosome.html
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#Centromere research yields new insights into the mechanisms of #chromosome #segregation errors.
https://phys.org/news/2024-05-centromere-yields-insights-mechanisms-chromosome.html
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#Centromere research yields new insights into the mechanisms of #chromosome #segregation errors.
https://phys.org/news/2024-05-centromere-yields-insights-mechanisms-chromosome.html
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#Centromere research yields new insights into the mechanisms of #chromosome #segregation errors.
https://phys.org/news/2024-05-centromere-yields-insights-mechanisms-chromosome.html
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#Centromere research yields new insights into the mechanisms of #chromosome #segregation errors.
https://phys.org/news/2024-05-centromere-yields-insights-mechanisms-chromosome.html
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Secrets of #cell_division revealed by cutting-edge imaging technique.
#cohesin #microscopy #chromatids
https://phys.org/news/2024-03-secrets-cell-division-revealed-edge.html
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Secrets of #cell_division revealed by cutting-edge imaging technique.
#cohesin #microscopy #chromatids
https://phys.org/news/2024-03-secrets-cell-division-revealed-edge.html
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Secrets of #cell_division revealed by cutting-edge imaging technique.
#cohesin #microscopy #chromatids
https://phys.org/news/2024-03-secrets-cell-division-revealed-edge.html
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Super happy to share my first co-authored publication, a review on loop extrusion modeling by cohesins! @golobor, Flavia Corsi and I review recent discoveries made by the modeling of loop extrusion, the "rules" behind these models and propose future enhancements to models based on recent insights on the mechanism and regulation of cohesin-driven loop extrusion. Give it a read: https://authors.elsevier.com/c/1hIIR,LqAZXo9S #review #computationalBiology #3Dgenome #loopExtrusion #cohesin
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Super happy to share my first co-authored publication, a review on loop extrusion modeling by cohesins! @golobor, Flavia Corsi and I review recent discoveries made by the modeling of loop extrusion, the "rules" behind these models and propose future enhancements to models based on recent insights on the mechanism and regulation of cohesin-driven loop extrusion. Give it a read: https://authors.elsevier.com/c/1hIIR,LqAZXo9S #review #computationalBiology #3Dgenome #loopExtrusion #cohesin
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Super happy to share my first co-authored publication, a review on loop extrusion modeling by cohesins! @golobor, Flavia Corsi and I review recent discoveries made by the modeling of loop extrusion, the "rules" behind these models and propose future enhancements to models based on recent insights on the mechanism and regulation of cohesin-driven loop extrusion. Give it a read: https://authors.elsevier.com/c/1hIIR,LqAZXo9S #review #computationalBiology #3Dgenome #loopExtrusion #cohesin
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Super happy to share my first co-authored publication, a review on loop extrusion modeling by cohesins! @golobor, Flavia Corsi and I review recent discoveries made by the modeling of loop extrusion, the "rules" behind these models and propose future enhancements to models based on recent insights on the mechanism and regulation of cohesin-driven loop extrusion. Give it a read: https://authors.elsevier.com/c/1hIIR,LqAZXo9S #review #computationalBiology #3Dgenome #loopExtrusion #cohesin
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#Cohesin can resolve sister #chromatids already in G2 phase independent of #condensin - suggesting DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different Structural Maintenance of #Chromosomes (SMC) protein complexes
Paul Batty, Daniel Gerlich et al #viennabiocenter
https://www.embopress.org/doi/10.15252/embj.2023113475 -
#Cohesin can resolve sister #chromatids already in G2 phase independent of #condensin - suggesting DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different Structural Maintenance of #Chromosomes (SMC) protein complexes
Paul Batty, Daniel Gerlich et al #viennabiocenter
https://www.embopress.org/doi/10.15252/embj.2023113475 -
#Cohesin can resolve sister #chromatids already in G2 phase independent of #condensin - suggesting DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different Structural Maintenance of #Chromosomes (SMC) protein complexes
Paul Batty, Daniel Gerlich et al #viennabiocenter
https://www.embopress.org/doi/10.15252/embj.2023113475 -
#Cohesin can resolve sister #chromatids already in G2 phase independent of #condensin - suggesting DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different Structural Maintenance of #Chromosomes (SMC) protein complexes
Paul Batty, Daniel Gerlich et al #viennabiocenter
https://www.embopress.org/doi/10.15252/embj.2023113475 -
Excellent review on NIPBL function and the different roles of STAG1 and STAG2 by Dácil Alonso-Gil and Ana Losada https://doi.org/10.1016/j.tcb.2023.03.006 lots to think about in here #chromatin #cdls #chromatindisorders
#cohesin #genetics -
Excellent review on NIPBL function and the different roles of STAG1 and STAG2 by Dácil Alonso-Gil and Ana Losada https://doi.org/10.1016/j.tcb.2023.03.006 lots to think about in here #chromatin #cdls #chromatindisorders
#cohesin #genetics -
Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody
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Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody
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Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody
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Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody
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Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody
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CTCF binds to DNA and acts as a barrier to #cohesin, regulating its activity and restraining loop extrusion to specific areas of the genome. But how?
Read our news release to find out.👀⏬ (2/)
https://www.imp.ac.at/news/article/architects-of-the-genome -
CTCF binds to DNA and acts as a barrier to #cohesin, regulating its activity and restraining loop extrusion to specific areas of the genome. But how?
Read our news release to find out.👀⏬ (2/)
https://www.imp.ac.at/news/article/architects-of-the-genome -
CTCF binds to DNA and acts as a barrier to #cohesin, regulating its activity and restraining loop extrusion to specific areas of the genome. But how?
Read our news release to find out.👀⏬ (2/)
https://www.imp.ac.at/news/article/architects-of-the-genome -
CTCF binds to DNA and acts as a barrier to #cohesin, regulating its activity and restraining loop extrusion to specific areas of the genome. But how?
Read our news release to find out.👀⏬ (2/)
https://www.imp.ac.at/news/article/architects-of-the-genome -
CTCF binds to DNA and acts as a barrier to #cohesin, regulating its activity and restraining loop extrusion to specific areas of the genome. But how?
Read our news release to find out.👀⏬ (2/)
https://www.imp.ac.at/news/article/architects-of-the-genome -
The labs of Jan-Michael Peters and @leonidmirny @MIT have found how #genetranscription interferes with #cohesin-mediated loop extrusion. Transcription shapes genome organisation in unexpected ways!
The paper: https://www.pnas.org/doi/10.1073/pnas.2210480120
Our news article: https://www.imp.ac.at/news/article/gene-transcription-hampers-cohesins-travel-along-chromosomes -
The labs of Jan-Michael Peters and @leonidmirny @MIT have found how #genetranscription interferes with #cohesin-mediated loop extrusion. Transcription shapes genome organisation in unexpected ways!
The paper: https://www.pnas.org/doi/10.1073/pnas.2210480120
Our news article: https://www.imp.ac.at/news/article/gene-transcription-hampers-cohesins-travel-along-chromosomes -
The labs of Jan-Michael Peters and @leonidmirny @MIT have found how #genetranscription interferes with #cohesin-mediated loop extrusion. Transcription shapes genome organisation in unexpected ways!
The paper: https://www.pnas.org/doi/10.1073/pnas.2210480120
Our news article: https://www.imp.ac.at/news/article/gene-transcription-hampers-cohesins-travel-along-chromosomes -
The labs of Jan-Michael Peters and @leonidmirny @MIT have found how #genetranscription interferes with #cohesin-mediated loop extrusion. Transcription shapes genome organisation in unexpected ways!
The paper: https://www.pnas.org/doi/10.1073/pnas.2210480120
Our news article: https://www.imp.ac.at/news/article/gene-transcription-hampers-cohesins-travel-along-chromosomes -
The labs of Jan-Michael Peters and @leonidmirny @MIT have found how #genetranscription interferes with #cohesin-mediated loop extrusion. Transcription shapes genome organisation in unexpected ways!
The paper: https://www.pnas.org/doi/10.1073/pnas.2210480120
Our news article: https://www.imp.ac.at/news/article/gene-transcription-hampers-cohesins-travel-along-chromosomes -
Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with https://authors.elsevier.com/a/1g4Hg1SPT0FkK
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Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with https://authors.elsevier.com/a/1g4Hg1SPT0FkK
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Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with https://authors.elsevier.com/a/1g4Hg1SPT0FkK
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Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with https://authors.elsevier.com/a/1g4Hg1SPT0FkK
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IF you want to get a quick idea what we are working on see the talk of my PhD student Aymen Attou on youtube at the "Nuclear architecture & Function" symposium in Toulouse https://www.youtube.com/watch?v=mPneWhIBRAg #chromatin #ctcf #cohesin
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I am excited to be at genomic.social #introduction. I am interested in understanding the spatial structure of #chromatin and its regulation e.g. by nucleosome positions or #cohesin. My lab uses Monte Carlo simulations with a resolution of single nucleosomes of regions up to 1 Mbp.
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I am excited to be at genomic.social #introduction. I am interested in understanding the spatial structure of #chromatin and its regulation e.g. by nucleosome positions or #cohesin. My lab uses Monte Carlo simulations with a resolution of single nucleosomes of regions up to 1 Mbp.
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I am excited to be at genomic.social #introduction. I am interested in understanding the spatial structure of #chromatin and its regulation e.g. by nucleosome positions or #cohesin. My lab uses Monte Carlo simulations with a resolution of single nucleosomes of regions up to 1 Mbp.
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I am excited to be at genomic.social #introduction. I am interested in understanding the spatial structure of #chromatin and its regulation e.g. by nucleosome positions or #cohesin. My lab uses Monte Carlo simulations with a resolution of single nucleosomes of regions up to 1 Mbp.
