#systemsneuroscience — Public Fediverse posts

Molecular atlas of the adult Drosophila melanogaster (fruit fly) brain demonstrates that neurons retain a genetic record of their developmental origins, and that sex-specific behavioral circuits arise from a shared developmental template. Rather than building entirely separate circuits, sexual dimorphism in the brain is achieved through selective neuronal survival within shared cell lineages.
#Neuroscience #Neurogenetics #DevelopmentalBiology #SystemsNeuroscience #sflorg
https://www.sflorg.com/2026/03/ns03152601.html

2 PhD student positions available in Koen Vervaeke's lab in Oslo:

1️⃣ Systems Neuroscience: Investigate hippocampal spatial memory & addiction mechanisms. (Tools: In vivo 2P imaging, ephys, optogenetics).

2️⃣ Neuro/Cancer Biology: The GLIOFORCE project. A unique collaboration with the Campsteijn Lab to track Glioblastoma invasion in vivo using mesoscope 2P imaging.

https://vervaeke-lab.org/Hiring

#neuroscience #PhDPositions #SystemsNeuroscience #glioblastoma

Funded postdoctoral position in human intracranial neuroscience
University of Rochester

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-rochester-27778-funded-postdoctoral-position-in-human-intracranial-neuroscience/

#behavioralneuroscience #biolinguistics #cognitiveneuroscience #psycholinguistics #systemsneuroscience #ScienceJob...
https://jobrxiv.org/job/university-of-rochester-27778-funded-postdoctoral-position-in-human-intracranial-neuroscience/?fsp_sid=5569

Postdoc position in ultrasound neuromodulation at UCSF
University of California San Francisco

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/

#neuralcircuits #neuroengineering #neuromodulation #systemsneuroscience #ultrasound #Science...
https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/?fsp_sid=4064

Postdoc position in ultrasound neuromodulation at UCSF
University of California San Francisco

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/

#neuralcircuits #neuroengineering #neuromodulation #systemsneuroscience #ultrasound #Science...
https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/?fsp_sid=2839

Postdoc position in ultrasound neuromodulation at UCSF
University of California San Francisco

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/

#neuralcircuits #neuroengineering #neuromodulation #systemsneuroscience #ultrasound #Science...
https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/?fsp_sid=1831

In their study, Morales-Gregorio et al. show that #NeuralManifolds in #V1 shift dynamically under top-down influence from #V4. They identify two distinct population activity states – eyes open vs. closed – with notably stronger V4→V1 signaling in the foveal region during eyes-open periods. A cool example of how cognitive context reshapes visual cortical dynamics.

🌍 https://www.cell.com/cell-reports/fulltext/S2211-1247(24)00699-5

#CompNeuro #Neuroscience #VisualCortex #NeuralManifolds #SystemsNeuroscience

@juangallego just published a review on how #NeuralManifolds go beyond being a convenient data representation – they reflect fundamental constraints on #NeuralPopulation activity. Originating in mammalian BCI work (2014), these low-dimensional trajectories shape what neural patterns are learnable and expressible.

🌍 https://www.nature.com/articles/s41583-025-00919-0.epdf

#CompNeuro #SystemsNeuroscience #PopulationDynamics #Neuroscience

A new study by Timothy Sit, Célian Bimbard, Anna Lebedeva, @MatteoCarandini, Philip Coen, and Kenneth Harris challenges the classic cortical column model. Using in vivo recordings, they show that layers 2/3 and 5 in #V1 encode distinct visual features — functionally dissociated, not redundant. A cool look into laminar specialization.

🌍 https://www.biorxiv.org/content/10.1101/2025.06.30.662366v2

#Neuroscience #VisualCortex #CorticalLayers #SystemsNeuroscience

Latest from Kathy Nagel's lab:

"Inhibitory control explains locomotor statistics in walking Drosophila", Gattuso et al. 2025
https://www.pnas.org/doi/abs/10.1073/pnas.2407626122

"we measure and analyze trajectories evoked by attractive odor in walking Drosophila and develop a biologically plausible computational model of trajectory generation and modulation by sensory input. Our model provides a link between neural architectures and locomotor behavior and highlights the potential role of inhibition in shaping the curvature and speed of trajectories. Inspired by this model, we experimentally identify single neurons and populations that modulate either curvature or speed in the manner predicted by our model."

#neuroscience #Drosophila #locomotion #CompNeurosci #SystemsNeuroscience

Amazing surprise #neuropod !!!

#BeyondPhrenology interviews
#MichaelLAnderson author of #AfterPhrenology
https://youtu.be/yEusfU6IWck

#SystemsNeuroscience
#PhilosophyOfNeuroscience
#PhilosophyOfMind
#PhilosophyOfAI
#Neuroscience
#neuroscienceresearch
#neuralReuse
#NetworkNeuroscience

Please join the @INCF + @OCNS Software Working group on 9th July for our next meeting.

Adam Tyson from the Sainsbury Wellcome Centre will talk about the software tools their group develops for systems neuroscience:

https://ocns.github.io/SoftwareWG/2024/06/26/wg-meeting-9-july-2024-software-tools-for-systems-neuroscience-adam-tyson-.html

#Software #FOSS #Neuroscience #SystemsNeuroscience #UCL #SWC

» Although the stated aim of the book is not to reform #neuroscience or offer advice to #neuroscientists
but rather to interpret their work,
I have not always kept myself within the bounds of description of scientific practice.

The prescriptive voice—on the folly of overestimating our comprehension of nature in itself, in its full complexity—does frequently come out. «
#TheBrainAbstracted
by #MazviitaChirimuuta https://mitpress.mit.edu/9780262548045/the-brain-abstracted/

#OpenAccess
#SystemsNeuroscience
#PhilosophyOfNeuroscience

@dcm

#MazviitaChirimuuta book
#TheBrainAbstracted povides citations from cool authors in #neurodon #neuroscience #SystemsNeuroscience #PhilosophyOfNeuroscience
#PhilosophyOfAI #philosophyofmind

@MatteoCarandini
@NancyKanwisher
@Neurograce
@garymarcus
@michelamassimi
@melaniemitchell
@Gualtiero
@kordinglab

From:
» what we called 'standard hypothesis'

..

Emotional stimuli are process initially, via a dedicated modular system that operates rapidly, automatically, in the sense of without attention, and largely independently of conscious awareness, and that defects..

..so this is not just a curiosity for researchers in the lab, it has enormous impact in in society.. «

To:
#heterarchy

A cool #neurolecture by @PessoaBrain
https://youtu.be/1fqM5FGQJdQ
#neuroscience
#neurobuzz
#systemsneuroscience

» But to what extent & at what scales
brain dynamics & function depend on the specific details of their nodes & edges

&, on the other hand,

to what extent
simple network structure retains sufficient information to account for brain structure, dynamics, & function

are not yet totally clear questions «

Does the brain behave like a (complex) network? I. Dynamics
https://doi.org/10.1016/j.plrev.2023.12.006

#complexsystems
#neurodon
#neurobuzz
#systemsneuroscience
#compneuro

HT subscribe:
https://mathstodon.xyz/@manlius/111744238092534983

By ironical serendiripy, drift, change, synchronicity, or else:

Two new papers with thoughtful #NetworkNeuroscience critique!

» Beyond Networks:
Explaining Dynamics in the Natural and Social Sciences «
@yoginho et al.
https://doi.org/10.31219/osf.io/htc78

» Circular and unified analysis in network neuroscience «
Mika Rubinov
https://doi.org/10.7554/eLife.79559

With different framework approaches, conclusions, while complimentary & so needed!

#ComplexSystems
#NetworkScience
#SystemsNeuroscience
#neurodon
#neurobuzz

@axoaxonic @sandervanbree

End of the Year 2023 Gift

Timely Surprise from
@Brains

What is #Explanation
in #Neuroscience ?

Quarteto 5-15m Lectures
by Dr #MazviitaChirimuuta

1
https://youtu.be/p_zkx2M6YYw
2
https://youtu.be/rd5Pl4UfIDA
3
https://youtu.be/CQmWyb2gn-U
4
https://youtu.be/zuj5Z8o_-5w

A Beginner's Guide To Neural Mechanisms
https://www.neuralmechanisms.org/explanation-in-neuroscience-chirimuuta.html

#complexsystems
#neurotheory
#mindbrain
#neurodon
#neurobuzz
#theoreticalneuroscience
#PhilosophyOfAI
#systemsneuroscience
#PhilosophyOfNeuroscience

» #neuroscience has become so broad & technically sophisticated that individual researchers can no longer fully understand the technical foundations of their experiments.

The average #systemsneuroscience project, for example, requires in-depth knowledge of animal #surgery #mechanical #optical & #electrical #engineering #statistics and #computerscience «

https://www.thetransmitter.org/systems-neuroscience/why-and-how-we-need-to-professionalize-neuroscience/

#neurodon
#neurobuzz
#systemsneuro

» #neuroscience has become so broad & technically sophisticated that individual researchers can no longer fully understand the technical foundations of their experiments.

The average #systemsneuroscience project, for example, requires in-depth knowledge of animal #surgery #mechanical #optical & #electrical #engineering #statistics and #computerscience «

https://www.thetransmitter.org/systems-neuroscience/why-and-how-we-need-to-professionalize-neuroscience/

#neurodon
#neurobuzz
#systemsneuro

» #neuroscience has become so broad & technically sophisticated that individual researchers can no longer fully understand the technical foundations of their experiments.

The average #systemsneuroscience project, for example, requires in-depth knowledge of animal #surgery #mechanical #optical & #electrical #engineering #statistics and #computerscience «

https://www.thetransmitter.org/systems-neuroscience/why-and-how-we-need-to-professionalize-neuroscience/

#neurodon
#neurobuzz
#systemsneuro

» #neuroscience has become so broad & technically sophisticated that individual researchers can no longer fully understand the technical foundations of their experiments.

The average #systemsneuroscience project, for example, requires in-depth knowledge of animal #surgery #mechanical #optical & #electrical #engineering #statistics and #computerscience «

https://www.thetransmitter.org/systems-neuroscience/why-and-how-we-need-to-professionalize-neuroscience/

#neurodon
#neurobuzz
#systemsneuro

» #neuroscience has become so broad & technically sophisticated that individual researchers can no longer fully understand the technical foundations of their experiments.

The average #systemsneuroscience project, for example, requires in-depth knowledge of animal #surgery #mechanical #optical & #electrical #engineering #statistics and #computerscience «

https://www.thetransmitter.org/systems-neuroscience/why-and-how-we-need-to-professionalize-neuroscience/

#neurodon
#neurobuzz
#systemsneuro

@kordinglab

apropos of NMDARs Glutamate:

fav top notch most impressive #scihistory #neurolecture ever!

"Unnoticed Features of Exploratory Experiments from the 60-Year History of the N-methyl - D-aspartate (NMDA) Receptor"
https://youtu.be/xrNrLcE2RZE
John Bickle
2023

From 1949 Hebb
'in one or both cells'
then Watkins, Morris, Collingridge, etc. to
2023 #PhilSci Haueis

#neurophysiology
#neurohistory
#neurodon
#neuroscience
#oldneuropapers
#cogsci
#neurobuzz
#systemsneuroscience
#complexsystems

Professor @melaniemitchell gives 2023 #MargaretBoden Lecture:

”the inability to form conceptual abstraction —and to make abstraction-driven analogies— is a primary source of brittleness and unreliability in #sota #AI”

”I think the the problem that AI has faced at least up till recently is that it has relied on #statistical associations rather than forming concepts”

https://youtu.be/uEN_rOxKkag

#LLMs #cogsci #neurobuzz #neurodon #ml #systemsneuroscience #complexsystems #neuroai #dl
#PhilosophyOfAI

Another #BrainInspired Cool Episode conversing @WiringtheBrain new book:

» what I’ve done in the book is sketch what I think is just really a framework for thinking about those things
...
that an organism could have causal power in and of itself and could could have control and could exercise choice.
...
even after having written this book, this question of choice is the one that still just niggles at me and «
https://braininspired.co/podcast/175/

#neuroscience
#neurobuzz
#systemsneuroscience
#freewill

Cool #BrainInspired Surprise:

#ContextChangesEverything comes about 25 years after her previous classic #DynamicsInAction

#AliciaJuarrero is a philosopher and has been interested in complexity since before it was cool

https://braininspired.co/podcast/174/

#complexsystems
#neurotheory
#NeuronalEnsemble
#mindbrain
#neurodon
#neuroscience
#neurobuzz
#constraints
#systemsneuroscience

» more theoretical thinking and less (unthinking) #ml or less confusion between #machinelearning and theory

Then #AI can be a useful theoretical tool...

The thesis of #computationalism implies that it is possible in principle to understand human cognition as a form of computation.
However, this does not imply that it is possible in practice to computationally (re)make cognition «

https://psyarxiv.com/4cbuv

#philosophyofneuroscience
#systemsneuroscience
#neuroscience
#neurotheory
@cognition

@manisha @Neurograce @neuroscience @cogsci @cogneurophys @PessoaBrain

@cian comment in thread reminded me:

@kordinglab recent talks on how #computationalneuroscience #ml methods, while spread across labs & papers, still face #neurotheory proven grounds:

Does the #brain do #gradientDescent ?
https://www.youtube.com/watch?v=E5hATeCZQnU

#causality for #neuroscience & beyond
https://www.youtube.com/watch?v=XUD69JshQTk

#philosophyofneuroscience
#systemsneuroscience
#mindbrain

ps: IMHO #ml yea: best when for discovery, not causality

@codinghorror
Like saying without telling fav #consciousness definition

» Hurrah I awake from yesterday «

Yet only stumbled upon reading #PattiSmith quoting #JimiHendrix when answering this fan question:
What brings you joy?

https://www.theguardian.com/music/2022/mar/31/i-experience-joy-very-easily-patti-smith-on-springsteen-the-climate-fight-and-the-meaning-of-punk

In JH atmospherical anti-war song:
“1983 ... (A Merman I Should Turn to Be)“
https://www.youtube.com/watch?v=3AeWMHW0aWM

#neuroscience
#neurotheory
#neurotech
#philosophyofmind
#philosophyofcognitivescience
#philosophyofneuroscience
#systemsneuroscience
#mindbrain

» By brain is meant, in the first instance, something more than the pink-grey jelly of the anatomist. It is, even to a scientist, the organ of imagination. «

W. Grey Walter

#neuroscience
#neurotheory
#neurotech
#philosophyofmind
#philosophyofcognitivescience
#philosophyofneuroscience
#systemsneuroscience
#mindbrain

» Every man can, if he so desires, become the sculptor of his own brain «

― Santiago Ramón y Cajal

https://www.discovermagazine.com/mind/the-scientist-who-drew-brains-and-then-a-nobel-prize

#neuroscience #cajal #botd #historyOfScience #neurodon
#cajalDay #RamonyCajal
#cognitiveNeuroscience
#PhilosophyOfMind
#SystemsNeuroscience
@neuroscience @cognition

» Despite the multidisciplinary explanatory effort, the feeling of being alive at issue still constitutes a major blind spot of contemporary affective sciences research.

There’s no shared definition nor consensus about its distinctive features. «

#Damasio #neurobiological modelling of #Exteroception #Proprioception #Interoception as clearly written by Emilia Barile
https://link.springer.com/article/10.1007/s11097-023-09900-7

#neuroscience
#cognitiveNeuroscience
@neuroscience
@cognition
#PhilosophyOfMind
#SystemsNeuroscience

This summer school looks pretty cool.
https://tenss.ro/index.php

#neuroscience #summerschool #systemsneuroscience #electrophysiology #opticalimaging #neuralcircuits