#neurohistory — Public Fediverse posts

@neurofrontiers

2 top my fav yt

1 Young had confirmed experimentally that the structures were nerve fibres. However, it was left to Hodgkin and Huxley to probe the axon’s inner workings
https://youtu.be/g2hysrWbuZs

2 Even in our times of quantitative models and computer hardware that would have flabbergasted Hodgkin and Huxley, wetlab interventionist experimentation must remain the principal activity in the search for neurobiological mechanisms
https://youtu.be/g85bgHul7Ns

#neurolecture #neurohistory

@DhananjayThakur

You might also enjoy this #neurolecture recalling #hodgkinhuxley #neurohistory seminal quintet of papers, remarking how became aware of their model limitations, written in the 1952 d/4th paper:

Forgotten lesson in nowadays #compneuro models research!

» wetlab interventionist experimentation must remain the principal activity in the search for neurobiological mechanisms, for the same reasons Hodgkin & Huxley realized nearly 70 years ago «

#JohnBickle

https://youtu.be/g85bgHul7Ns

@DhananjayThakur

How are seahorses neurons shaped?
How seahorses axons compare to the squids enlarged ones?

HT Your question reminded me of this unique #neurohistory video:

» Over 80 years ago a ground-breaking experiment undertaken at the Laboratory of the Marine Biological Association by Alan #Hodgkin and Andrew #Huxley helped launch a golden era of #neurobiology «
https://youtu.be/g2hysrWbuZs

@DhananjayThakur

How are seahorses neurons shaped?
How seahorses axons compare to the squids enlarged ones?

HT Your question reminded me of this unique #neurohistory video:

» Over 80 years ago a ground-breaking experiment undertaken at the Laboratory of the Marine Biological Association by Alan #Hodgkin and Andrew #Huxley helped launch a golden era of #neurobiology «
https://youtu.be/g2hysrWbuZs

@DhananjayThakur

How are seahorses neurons shaped?
How seahorses axons compare to the squids enlarged ones?

HT Your question reminded me of this unique #neurohistory video:

» Over 80 years ago a ground-breaking experiment undertaken at the Laboratory of the Marine Biological Association by Alan #Hodgkin and Andrew #Huxley helped launch a golden era of #neurobiology «
https://youtu.be/g2hysrWbuZs

@DhananjayThakur

How are seahorses neurons shaped?
How seahorses axons compare to the squids enlarged ones?

HT Your question reminded me of this unique #neurohistory video:

» Over 80 years ago a ground-breaking experiment undertaken at the Laboratory of the Marine Biological Association by Alan #Hodgkin and Andrew #Huxley helped launch a golden era of #neurobiology «
https://youtu.be/g2hysrWbuZs

@DhananjayThakur

How are seahorses neurons shaped?
How seahorses axons compare to the squids enlarged ones?

HT Your question reminded me of this unique #neurohistory video:

» Over 80 years ago a ground-breaking experiment undertaken at the Laboratory of the Marine Biological Association by Alan #Hodgkin and Andrew #Huxley helped launch a golden era of #neurobiology «
https://youtu.be/g2hysrWbuZs

@DrYohanJohn

#JohnBickle #neurohistory lecture:

#compneuro limits

A Hodgkin & A Huxley
1952s
Papers quartet duo written
—with one B Katz trio

Pioneering voltage-clamp squid neural implant.

First action potentials recordings!

Last paper on how maths calculus derived from experiments datasets.

Thus predictions caveat:
Never link causal mechanisms.

ps: Q&A critical feedback:
Skilled lecturer turns into scientific dialogues!

https://www.youtube.com/watch?v=g85bgHul7Ns

#oldneuropapers
#neuroscience
#neurobuzz

@kordinglab

apropos of NMDARs Glutamate:

fav top notch most impressive #scihistory #neurolecture ever!

"Unnoticed Features of Exploratory Experiments from the 60-Year History of the N-methyl - D-aspartate (NMDA) Receptor"
https://youtu.be/xrNrLcE2RZE
John Bickle
2023

From 1949 Hebb
'in one or both cells'
then Watkins, Morris, Collingridge, etc. to
2023 #PhilSci Haueis

#neurophysiology
#neurohistory
#neurodon
#neuroscience
#oldneuropapers
#cogsci
#neurobuzz
#systemsneuroscience
#complexsystems

@ekmiller

HT for linking this one!

Recalled that other yours multi lab teams efforts, from which learned tons, specifically because of the open review decision section #1 & #2 ;)
https://elifesciences.org/articles/60824

ps: nowadays phd/book worth effort is awaiting to be written on #neurotech #neurohistory evolution in par with #neurotheory #compneuro maths theorems & formulae employ, disregard, re-employ, & on & so forth.
Something like updated 2007 Nicolelis et al. Methods for Neural Ensemble Recordings.

@nadel

add some tags —even easily by editing after posting— to improve such kind of cool posts, ie:

#neurohistory
#neurodon
#neuroscience
#oldneuropapers

cc
@NicoleCRust for aditional tag suggestions!