#neurogenetics — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #neurogenetics, aggregated by home.social.
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Molecular atlas of the adult Drosophila melanogaster (fruit fly) brain demonstrates that neurons retain a genetic record of their developmental origins, and that sex-specific behavioral circuits arise from a shared developmental template. Rather than building entirely separate circuits, sexual dimorphism in the brain is achieved through selective neuronal survival within shared cell lineages.
#Neuroscience #Neurogenetics #DevelopmentalBiology #SystemsNeuroscience #sflorg
https://www.sflorg.com/2026/03/ns03152601.html -
Ion Channels and Neurotransmitters: The Building Blocks of Brain Activity
#Neuroscience #BrainScience #Neurobiology #SynapticTransmission #Neurogenetics #BrainHealth #Neuroplasticity #IonChannels #MentalHealth #Neurodegeneration
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#Dros24 will be at #TAGC24! Hear the latest #Drosophila research plus other organism-specific content & broader topic-driven insights 🪰🧬 Reconnect & form new collaborations with scientists from all over the world. Submit an abstract & register: https://bit.ly/3RVnh7I
Learn about #neurogenetics, #diseasemodels & aging, developmental #genetics, #genomes & #genomics, evolution, #cellbiology, patterning, #morphogenesis, #organogenesis, & more! -
APOE expression and secretion are modulated by mitochondrial dysfunction
This study presents compelling evidence that ApoE is upregulated in various models of mitochondrial respiratory chain dysfunction. The work is of fundamental interest for those studying neurodegeneration and the role of ApoE in Alzheimer's disease; future work will be needed to reveal the molecular basis of this dramatic phenotype.
#Biomedicine #Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #ApoE #Neurogenetics #Mitochondria #MitochondrialDysfunction
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Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man
The male remained cognitively intact until 67 years of age despite carrying a PSEN1-E280A mutation. He had extremely elevated amyloid plaque burden and limited entorhinal Tau tangle burden.
He was heterozygous for a rare variant in RELN showing stronger ability to reduce human Tau phosphorylation in a knockin mouse.#Biomedicine #Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #Tau #Reelin #ApoE #Dementia #Neurogenetics