#neuromodulation — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #neuromodulation, aggregated by home.social.
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New preprint on #neuromodulation in #SpikingNeuralNetworks of interest to people in #neuroscience and #neuromorphic computing.
Headline result: neuromodulation gives a huge boost to performance, particularly in noisy environments, and reduces energy consumption by reducing neuron and spike counts.
We also have tutorials and codes to integrate easily into your models.
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The Brain’s Chemistry Party: How Neurotransmitters, Circuits, and Nature Keep Our Minds in Tune
#BrainHealth #Neurotransmitters #MentalHealth #Neuroscience #BrainCircuits #Pharmacology #Neuromodulation #StressResponse #MolecularNeuroscience #HolisticHealth #Biohacking #Neurobiology #NaturalHealing #BrainChemistry
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Happy & proud to share our latest work with the #bluespot community, #locuscoeruleus enthusiasts, and anyone else willing to read 😉
https://www.biorxiv.org/content/10.1101/2023.10.16.562534v1
4 years ago, we had the idea that endogenous neuromodulatory systems are in place that control LC activity, thereby promoting adaptive behavioral responses in challenging environments.
We examined the role of Neuropeptide Y, as a possible candidate system for this, and identified a new population of #NPY-expressing neurons, distributed in the pericoerulean space.
We showed that peri-LC NPY cells innervate the region, providing #NPY input onto #noradrenergic neurons of the LC, and strongly inhibiting their activity, via Y1Rs.
Next, we showed that chemogenetic stimulation of NPY cells led to anxiety-relief, via Y1Rs, and conversely, inhibition of NPY neurons triggered an anxiogenic phenotype.
Together, we showed a novel role for NPY-mediated #neuromodulation of the LC in adaptive behaviors.
We re happy to hear your thoughts /ideas /feedback on our data.
Please share/boost. Happy reading 🔵