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98 results for “socreatory”
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👀 Schaut mal, was wir hier haben...
Arcard von @feststelltaste ist endlich da! Nächste Woche gibt es ein Unboxing und mehr Informationen für euch!
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👀 Schaut mal, was wir hier haben...
Arcard von @feststelltaste ist endlich da! Nächste Woche gibt es ein Unboxing und mehr Informationen für euch!
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Do #lipid rafts play a role in trafficking in the secretory pathway? #GolgiApparatus. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/89306?utm_source=mastodon&utm_medium=social&utm_campaign=organic
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Is it possible to stop cellular #senescence? That’s the aim of senolytic drugs.
This #PLOSBiology Perspective looks at how discovery of the senescence-associated secretory phenotype enabled the development of #senolytics.
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#Toxoplasma relies on specialized secretory organelles for invasion & host cell manipulation. @ToxInLA &co identifies the TBC domain protein TBC9 as an essential regulator of the #GTPase Rab2 that controls intracellular vesicular trafficking #PLOSBiology https://plos.io/3Upgkvu
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CW: #MindOverMagic by #Klei playtest feedback. No spoilers.
I just love this game, and I clocked 24 hours or gameplay in 2 separate settings over 2 days😂 so clearly, I am loving it.
I have loong been waiting for a magic game. I've been following #WitchBrook from the screators of #Starbound, but that isn't going anywhere.
#MindOverMagic drops you into the same gameplay type and loop you could expect with #OxygenNotIncluded, but with less intense systems of physics and more magic Harry Potter style gameplay.
You are tasked with building a magic university. You have your trained mages and need to train students. They can graduate. Which gives you this market of training and sending students away or making them part of your university.
You then need to do dungeon battles to help progress your research tree, and it also has resource farming similar to #ONI.
Honestly, I love the game. I will finish it now, and then once the game is out, I'll buy it after a few updates.
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A receptor protein called TGN46 has an important role in sorting secretory proteins into vesicles going to different destinations inside cells. #Golgi https://elifesciences.org/articles/93490?utm_source=mastodon&utm_medium=social&utm_campaign=organic_insights
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Some great tips for ER fixation here:
https://focalplane.biologists.com/2023/11/02/community-collective-imaging-the-secretory-pathway/
Our experience is also that ER fixation can be tricky. One glutaraldehyde-free method that we have used is fixing for 2 h in 2% paraformaldehyde in 87.5 mM lysine, 87.5 mM sodium phosphate, pH 7.4, and 10 mM sodium periodate.
#EndoplasmicReticulum #CellBiology #Microscopy #MembraneTrafficking
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How are specific cargos targeted to apical & basolateral domains within #EpithelialCells? This study uses a novel #vesicle tracking software "MSP-tracker" to show that the secretory pathway in #Drosophila follicle cells is unexpectedly spatially organized @PLOSBiology https://plos.io/3EfJsBp
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Tierethische Bewertung der #Qualzucht-Problematik beim #CavalierKingCharlesSpaniel
Fakten, welche die Wahrscheinlichkeit einer Reihe von zuchtbedingten Defekten der Belastungskategorien 2-3 (mittlere bis starke Belastung) bzw. 3 (starke Belastung) auflisten, ist aus tierethischer Sicht festzustellen, dass die Weiterzucht mit betroffenen Tieren dieser Rasse als höchst problematisch einzustufen ist, da ein Züchter davon ausgehen muss, dass Tiere, die er durch seine Zucht in die Welt setzt, erheblich und andauernd Schmerzen ertragen müssen oder leiden werden.
https://qualzucht-datenbank.eu/merkblatt-hund-rasse-cavalier-king-charles-spaniel/
Brachycephalie
BOAS
Chiari-ähnliche Malformation/Syringomyelie
Mitralklappenerkrankungen
Augenerkrankungen
Kongenitale Keratoconjunctivitis sicca und Ichthyosiforme Dermatose Dry Eye Curly Coat Syndrom
Chondrodystrophie und Chondrodysplasie inkl. Bandscheibenerkrankungen
Degenerative Myelopathie
Primary secretory otitis media
Zahnerkrankungen und Erkrankungen des Zahnhalteapparats
Episodic Falling Syndrome.
#dogsofmastdon #Hunde -
Systems biology of #thyroid_homeostasis: Relational stability of two intertwined feedback loops protects #FT3 concentration despite variations in #thyroid's secretory capacity. https://doi.org/10.1177/20420188231158163
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This landmark #ReviewedPreprint represents “the most significant breakthrough in membrane and secretory biogenesis in recent years.”
‘Structural analysis of the dynamic ribosome-translocon complex’
https://elifesciences.org/reviewed-preprints/95814v2?utm_source=mastodon&utm_medium=social&utm_campaign=organic -
This landmark #ReviewedPreprint represents “the most significant breakthrough in membrane and secretory biogenesis in recent years.”
‘Structural analysis of the dynamic ribosome-translocon complex’
https://elifesciences.org/reviewed-preprints/95814v2?utm_source=mastodon&utm_medium=social&utm_campaign=organic -
St. Finbarr’s Oratory at Dawn
Nine exposures, three positions, and a lake disturbed by a biting wind. That’s what it took to stitch this panorama together at Gougane Barra just after dawn. The sky refused to cooperate with anything dramatic, so I leaned on the scene itself: the oratory sitting quietl...
https://inphotos.org/2026/03/29/st-finbarrs-oratory-at-dawn/
#Cork #GouganeBarra #hdr #Ireland #lake #LandscapePhotography #panorama #Photo #reflection #StFinbarr'sOratory #sunrise #Water
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Should we, therefore, classify #syndrome_T as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic #neuropathy that depend on autoimmunity and #thyroid's secretory capacity (#SPINA_GT).
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Another landmark paper represents “the most significant breakthrough in membrane and secretory biogenesis in recent years” with evidence deemed “exceptional”.
These are the highest assessment terms given for eLife papers! #12DaysOfeLife
https://elifesciences.org/articles/95814?utm_source=mastodon&utm_medium=social&utm_campaign=organic -
This study characterised the unconventional secretory mechanism of α-synuclein, an important contributor to #neurodegeneration. This time-lapse shows the movement of green α-synuclein in enlarged endosomes. #12DaysOfeLife https://elifesciences.org/articles/85837?utm_source=mastodon&utm_medium=social&utm_campaign=organic_12days
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Oh hey IgA ...Very interested to see what @ImmunoFever @JenGommerman @SalmaSheikhM_ @toxicWeeCell and @awyllie13 think about this one... doesn't look like secretory component/secretory chain was teased out #MucosalImmunology #IgA https://www.nature.com/articles/s41467-023-37368-1
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RT @ahandvanish
New paper on CD8+ T cells in #LongCovid that is way over my head; anyone have a simple explanation?https://www.nature.com/articles/s41…
https://twitter.com/ahandvanish/status/1643006628189425664 -
#ScienceMag Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly https://www.science.org/doi/10.1126/science.adg1075 A crucial mechanism that mediates the delivery of synaptic vesicle and active zone proteins to developing synapses. Precursor vesicles are distinct from conventional secretory organelles, endosomes, and degradative lysosomes and are transported by coincident detection of PI(3,5)P2 and active ARL8 via kinesin KIF1A to the presynaptic compartment.
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The #pituitary and #stress: #scRNAseq reveals that systemic inflammatory stress alters gene expression of all #PituitaryHormone-producing cells, increasing expression of many secretory factors & fostering interactions with immune cells #PLOSBiology https://plos.io/41tW2Ec
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#Thyroid's secretory (#SPINA_GT) is higher in borderline personality disorder (#BPD) compared to controls. Is this a result of dynamical compensation or from sympathetic innervation of the thyroid gland? https://doi.org/10.3390/jcm12216702
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- SUN X, Ma H, Wang X, Bao Z, et al.
Broadly neutralizing antibodies to combat influenza virus infection.
Antiviral Res. 2023 Dec 23:105785. doi: 10.1016/j.antiviral.2023.105785.
PubMed: https://www.amedeo.com/p2.php?id=38145757&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38145757 - MAHASE E.
England and Scotland see sharp rise in covid and flu cases as hospitals struggle.
BMJ. 2023;383:2977.
PubMed: https://www.amedeo.com/p2.php?id=38128963&s=flu&pm=2
Share: https://m.amedeo.com/38128963 - LOOI MK.
Covid-19: WHO adds JN.1 as new variant of interest.
BMJ. 2023;383:p2975.
PubMed: https://www.amedeo.com/p2.php?id=38128957&s=flu&pm=2
Share: https://m.amedeo.com/38128957 - MATTESON NL, Hassler GW, Kurzban E, Schwab MA, et al.
Genomic surveillance reveals dynamic shifts in the connectivity of COVID-19
epidemics.
Cell. 2023;186:5690-5704.
PubMed: https://www.amedeo.com/p2.php?id=38101407&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38101407 - WIDAGDO W, Bastian AR, Jastorff AM, Scheys I, et al.
Concomitant Administration of Ad26.RSV.preF/RSV preF Protein Vaccine and
High-dose Influenza Vaccine in Adults 65 Years and Older: a Noninferiority Trial.
J Infect Dis. 2023 Dec 22:jiad594. doi: 10.1093.
PubMed: https://www.amedeo.com/p2.php?id=38134393&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38134393 - MIURA K, Suzuki Y, Ishida K, Arakawa M, et al.
Distinct motifs in the E protein are required for SARS-CoV-2 virus particle
formation and lysosomal deacidification in host cells.
J Virol. 2023 Oct 13:e0042623. doi: 10.1128/jvi.00426.
PubMed: https://www.amedeo.com/p2.php?id=37830820&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37830820 - MAHE D, Bourgeau S, da Silva J, Schlederer J, et al.
SARS-CoV-2 replicates in the human testis with slow kinetics and has no major
deleterious effects ex vivo.
J Virol. 2023 Oct 13:e0110423. doi: 10.1128/jvi.01104.
PubMed: https://www.amedeo.com/p2.php?id=37830818&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37830818 - KIMURA I, Yamasoba D, Nasser H, Ito H, et al.
Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological
characteristics.
J Virol. 2023 Oct 5:e0101123. doi: 10.1128/jvi.01011.
PubMed: https://www.amedeo.com/p2.php?id=37796123&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37796123 - ZHAO Y, Sui L, Wu P, Li L, et al.
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus
replication through the E3 ubiquitin ligase MARCH8.
J Virol. 2023 Sep 29:e0102823. doi: 10.1128/jvi.01028.
PubMed: https://www.amedeo.com/p2.php?id=37772822&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37772822 - LI J, Gui Q, Liang FX, Sall J, et al.
The REEP5/TRAM1 complex binds SARS-CoV-2 NSP3 and promotes virus replication.
J Virol. 2023 Sep 28:e0050723. doi: 10.1128/jvi.00507.
PubMed: https://www.amedeo.com/p2.php?id=37768083&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37768083 - MCCOOL RS, Musayev M, Bush SM, Derrien-Colemyn A, et al.
Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein
elicits antibodies targeting a membrane-proximal epitope.
J Virol. 2023 Sep 22:e0092923. doi: 10.1128/jvi.00929.
PubMed: https://www.amedeo.com/p2.php?id=37737588&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37737588 - SCHOEN A, Holzer M, Muller MA, Wallerang KB, et al.
Functional comparisons of the virus sensor RIG-I from humans, the microbat Myotis
daubentonii, and the megabat Rousettus aegyptiacus, and their response to
SARS-CoV-2 infection.
J Virol. 2023 Sep 20:e0020523. doi: 10.1128/jvi.00205.
PubMed: https://www.amedeo.com/p2.php?id=37728614&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37728614 - FUJITA S, Kosugi Y, Kimura I, Tokunaga K, et al.
Determination of the factors responsible for the tropism of SARS-CoV-2-related bat coronaviruses to Rhinolophus bat ACE2.
J Virol. 2023 Sep 19:e0099023. doi: 10.1128/jvi.00990.
PubMed: https://www.amedeo.com/p2.php?id=37724881&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37724881 - CAO J, Shi M, Zhu L, Li X, et al.
The matrix protein of respiratory syncytial virus suppresses interferon signaling via RACK1 association.
J Virol. 2023;97:e0074723.
PubMed: https://www.amedeo.com/p2.php?id=37712706&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37712706 - XING M, Wang Y, Wang X, Liu J, et al.
Broad-spectrum vaccine via combined immunization routes triggers potent immunity to SARS-CoV-2 and its variants.
J Virol. 2023 Sep 14:e0072423. doi: 10.1128/jvi.00724.
PubMed: https://www.amedeo.com/p2.php?id=37706688&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37706688 - EASTMAN Q.
Study Shows Businesses Selling Unapproved Stem Cell Treatments Have Turned to Long COVID.
JAMA. 2023 Nov 29. doi: 10.1001/jama.2023.23897.
PubMed: https://www.amedeo.com/p2.php?id=38019493&s=flu&pm=2
Share: https://m.amedeo.com/38019493 - STEWART TG, Rebolledo PA, Mourad A, Lindsell CJ, et al.
Higher-Dose Fluvoxamine and Time to Sustained Recovery in Outpatients With COVID-19: The ACTIV-6 Randomized Clinical Trial.
JAMA. 2023 Nov 17:e2323363. doi: 10.1001/jama.2023.23363.
PubMed: https://www.amedeo.com/p2.php?id=37976072&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/37976072 - HARRINGTON PR, Cong J, Troy SB, Rawson JMO, et al.
Evaluation of SARS-CoV-2 RNA Rebound After Nirmatrelvir/Ritonavir Treatment in Randomized, Double-Blind, Placebo-Controlled Trials – United States and International Sites, 2021-2022.
MMWR Morb Mortal Wkly Rep. 2023;72:1365-1370.
PubMed: https://www.amedeo.com/p2.php?id=38127674&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38127674 - SMITH DJ, Lambrou A, Patel P.
SARS-CoV-2 Rebound With and Without Use of COVID-19 Oral Antivirals.
MMWR Morb Mortal Wkly Rep. 2023;72:1357-1364.
PubMed: https://www.amedeo.com/p2.php?id=38127665&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38127665 - FINNEY J, Moseman AP, Kong S, Watanabe A, et al.
Protective human antibodies against a conserved epitope in pre- and postfusion influenza hemagglutinin.
Proc Natl Acad Sci U S A. 2024;121:e2316964120.
PubMed: https://www.amedeo.com/p2.php?id=38147556&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38147556 - CHEN Y, Gel YR, Marathe MV, Poor HV, et al.
A simplicial epidemic model for COVID-19 spread analysis.
Proc Natl Acad Sci U S A. 2024;121:e2313171120.
PubMed: https://www.amedeo.com/p2.php?id=38147553&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38147553 - YE Z, Bonam SR, McKay LGA, Plante JA, et al.
Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants.
Proc Natl Acad Sci U S A. 2023;120:e2311752120.
PubMed: https://www.amedeo.com/p2.php?id=38134199&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38134199 - MIYAMOTO S, Nishiyama T, Ueno A, Park H, et al.
Infectious virus shedding duration reflects secretory IgA antibody response latency after SARS-CoV-2 infection.
Proc Natl Acad Sci U S A. 2023;120:e2314808120.
PubMed: https://www.amedeo.com/p2.php?id=38134196&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38134196 - GHARPURE R, Akumu AO, Dawa J, Gobin S, et al.
Costs of seasonal influenza vaccine delivery in a pediatric demonstration project for children aged 6-23 months – Nakuru and Mombasa Counties, Kenya, 2019-2021.
Vaccine. 2023 Dec 27:S0264-410X(23)01475-5. doi: 10.1016/j.vaccine.2023.
PubMed: https://www.amedeo.com/p2.php?id=38154992&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38154992 - FONSECA HAR, Zimerman A, Monfardini F, Guimaraes HP, et al.
In-Hospital influenza vaccination to prevent cardiorespiratory events in the first 45 days after acute coronary syndrome: A prespecified analysis of the VIP-ACS trial.
Vaccine. 2023 Dec 27:S0264-410X(23)01531-1. doi: 10.1016/j.vaccine.2023.
PubMed: https://www.amedeo.com/p2.php?id=38154990&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38154990 - SEPPALA E, Dahl J, Veneti L, Rydland KM, et al.
Covid-19 and influenza vaccine effectiveness against associated hospital admission and death among individuals over 65 years in Norway: A population-based cohort study, 3 October 2022 to 20 June 2023.
Vaccine. 2023 Dec 22:S0264-410X(23)01496-2. doi: 10.1016/j.vaccine.2023.
PubMed: https://www.amedeo.com/p2.php?id=38142215&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38142215 - KRISTENSEN C, Larsen LE, Trebbien R, Jensen HE, et al.
The avian influenza A virus receptor SA-alpha2,3-Gal is expressed in the porcine nasal mucosa sustaining the pig as a mixing vessel for new influenza viruses.
Virus Res. 2023 Dec 22:199304. doi: 10.1016/j.virusres.2023.199304.
PubMed: https://www.amedeo.com/p2.php?id=38142890&s=flu&pm=2
ABSTRACT available
Share: https://m.amedeo.com/38142890
#COVID19 #flu #health #influenza #influenzaA #research #seasonalInfluenza #vaccine
- SUN X, Ma H, Wang X, Bao Z, et al.
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Should we, therefore, classify #syndrome_T as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic #neuropathy that depend on autoimmunity and #thyroid's secretory capacity (#SPINA_GT).
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Should we, therefore, classify #syndrome_T as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic #neuropathy that depend on autoimmunity and #thyroid's secretory capacity (#SPINA_GT).
-
Should we, therefore, classify #syndrome_T as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic #neuropathy that depend on autoimmunity and #thyroid's secretory capacity (#SPINA_GT).
-
The #pituitary and #stress: #scRNAseq reveals that systemic inflammatory stress alters gene expression of all #PituitaryHormone-producing cells, increasing expression of many secretory factors & fostering interactions with immune cells #PLOSBiology https://plos.io/41tW2Ec
