#reviewedpreprint — Public Fediverse posts

This landmark #ReviewedPreprint represents “the most significant breakthrough in membrane and secretory biogenesis in recent years.”

‘Structural analysis of the dynamic ribosome-translocon complex’
https://elifesciences.org/reviewed-preprints/95814v2?utm_source=mastodon&utm_medium=social&utm_campaign=organic

​​This landmark #ReviewedPreprint represents “the most significant breakthrough in membrane and secretory biogenesis in recent years.”

‘Structural analysis of the dynamic ribosome-translocon complex’
https://elifesciences.org/reviewed-preprints/95814v2?utm_source=mastodon&utm_medium=social&utm_campaign=organic

What’s it actually like to publish a #ReviewedPreprint with eLife?

We asked author Chunxiao Li, a palaeontologist at the University of Chinese Academy of Sciences. Read about her experience.
https://elifesciences.org/inside-elife/f87ed206/author-experience-innovative-and-intriguing?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Most species have two sexes. The protist Tetrahymena thermophila has seven.

This fundamental #ReviewedPreprint reveals how it recognises self and non-self mating-types with a novel protein complex. https://elifesciences.org/reviewed-preprints/93770?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Biomineralisation appears to have evolved multiple times using different materials. This #ReviewedPreprint reveals how ROCK, an actomyosin remodelling protein, controls the process in sea urchin larvae. https://elifesciences.org/reviewed-preprints/89080?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #ReviewedPreprint presents a method to fluorescently label peptide MHC complexes on live dendritic cells, allowing for a better understanding of antigen-specific T cell interactions.

Public reviews by @eLife.

https://sciety.org/articles/activity/10.21203/rs.3.rs-3193191/v2?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2024_15

Analysing T cell motion in different tissue environments: many parameters of T cell motion are similar across tissues, with the exception of parameters related to confinement.

#ReviewedPreprint with public reviews by @eLife.

https://sciety.org/articles/activity/10.1101/2022.11.17.516891?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2024_13

The origins of RNA viruses can be hard to trace. This #ReviewedPreprint considers a more recent origin for coronaviruses and suggests their diversification occurred mainly through host switching rather than diversification with hosts. https://elifesciences.org/reviewed-preprints/91745?utm_source=mastodon&utm_medium=social&utm_campaign=organic

The balance of mTOR complexes in Sertoli cells regulates the rate of sperm epigenetic ageing, new #ReviewedPreprint reports.

Public reviews by @eLife.

https://sciety.org/articles/activity/10.1101/2023.05.23.541978?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2024_01

What controls the repair of photosystem II, a key process in maintaining and optimising photosynthesis?

Tryptophan oxidation plays a critical role, new #ReviewedPreprint with public reviews by @eLife suggests.

https://sciety.org/articles/activity/10.1101/2023.04.20.537607?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_209

Reviewers of this #ReviewedPreprint on ageing and senescence changed their assessment of the evidence from “incomplete” to “compelling” following the latest revisions by authors. Take a look at the reviews and version histories here: https://elifesciences.org/reviewed-preprints/87811v2?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #ReviewedPreprint improves gene models for the ferret genome and identifies neural progenitors that are comparable to those found in developing human brains.

Public reviews by @eLife.

https://sciety.org/articles/activity/10.1101/2022.05.05.490846?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_210

A new study reveals key mechanisms of rare form of early-onset epilepsy. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/91204?utm_source=mastodon&utm_medium=social&utm_campaign=organic_pr

A new method to therapeutically harness myeloid cells which can be otherwise immunosuppressive and hamper T cell and immunotherapy responses – #ReviewedPreprint with public reviews by @eLife.

https://sciety.org/articles/activity/10.1101/2023.09.30.560338?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2024_02

New #ReviewedPreprint explores how transcription factors regulate transcription through cooperative binding to enhancers in Drosophila.

Check out the full preprint with public reviews by @eLife.

https://sciety.org/articles/activity/10.1101/2023.01.05.522923?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_208

New #ReviewedPreprint presents a tool to identify lysosome-associated proteins in C. elegans.

Read the full article and the public reviews by @eLife.

https://sciety.org/articles/activity/10.1101/2022.10.16.512400?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_191

Reviewers of this #ReviewedPreprint on ageing and #senescence changed their assessment of the evidence from “incomplete” to “compelling” following the latest revisions by authors. Take a look at the reviews and version histories here: https://elifesciences.org/reviewed-preprints/87811v2?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Disentangling the relationship between cancer mortality and COVID-19. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/93758?utm_source=mastodon&utm_medium=social&utm_cam​​paign=organic

A cancer gene drives immune escape by stopping tumours and immune cells communicating using exosomes. #Cancer #ReviewedPreprint https://elifesciences.org/reviewed-preprints/95191?utm_source=mastodon&utm_medium=social&utm_campaign=organic_pr

This #ReviewedPreprint investigates the predictive role of circulating tumor DNA in the prognosis of patients with metastatic triple-negative #BreastCancer.

Public reviews by @eLife.

https://sciety.org/articles/activity/10.1101/2023.07.04.23292206?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_192

“This important study in the protozoan parasite Toxoplasma gondii significantly advances our understanding of calcium signalling mediated by the kinase CDPK1 in this species,” @eLife editors say about this #ReviewedPreprint

https://sciety.org/articles/activity/10.1101/2023.01.11.523553?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_207

“This fundamental discovery establishes a new standard for the field of lymphatic physiology,” @eLife editors say about this #ReviewedPreprint that identifies the pacemaker cells that drive lymphatic pumping.

https://sciety.org/articles/activity/10.1101/2023.08.24.554619?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_193

Insights into ulcerative colitis: The vesicular trafficking protein Rab7 maintains homeostasis in the gut by regulating the secretion of a protein called CLCA1. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/89776?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Researchers explore a large and “solid” dataset on the surprisingly diverse diets of a group of toothed birds that lived over 100 million years ago called Enantiornithines, or “opposite birds.” #ReviewedPreprint https://elifesciences.org/reviewed-preprints/89871v2?utm_source=mastodon&utm_medium=social&utm_campaign=organic

A method for imaging massive quantities of cell populations in centimetre-wide tissue and embryo. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/93633/?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Autotrophic growth of E. coli is achieved by a small number of genetic changes. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/88793?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Researchers are looking in detail at how the ridges of our fingerprints deform and what that could tell us about our sense of touch. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/93554?utm_source=mastodon&utm_medium=social&utm_campaign=organic

β-carotene accelerates the resolution of atherosclerosis in mice. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/87430?utm_source=mastodon&utm_medium=social&utm_campaign=organic

A valuable syngeneic #zebrafish model for studying #glioblastoma. #Cancer #CancerBiology #ReviewedPreprint https://elifesciences.org/reviewed-preprints/93077?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #ReviewedPreprint investigates the regulatory role of Mecp2 in #quiescence exit, providing “fundamental insights” into the mechanism controlling the #CellCycle.

#Preprint with public reviews by @eLife.

https://sciety.org/articles/activity/10.1101/2023.07.24.550263?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_190

Chromatin is less mobile during S-phase compared to G1 and G2 phases of the #CellCycle, new study finds.

#ReviewedPreprint with public reviews by @eLife-

https://sciety.org/articles/activity/10.1101/2023.03.07.531331?utm_source=mastodon&utm_medium=social&utm_campaign=sci_mastodon_2023_177

A molecular proofreading system originating from archaea offers plants resistance to toxic aldehydes and genetically modifying plants to overexpress it can make them more stress-resistant. #ReviewedPreprint #PlantBiology #Transgenics #GeneticEngineering https://elifesciences.org/reviewed-preprints/92827?utm_source=mastodon&utm_medium=social&utm_campaign=organic

These fly guys were snapped by the Kākāpō Recovery Team as they worked with soil environmental DNA to monitor one of the last surviving populations of the critically endangered #kākāpō 🦜 #ReviewedPreprint #12DaysOfeLife https://elifesciences.org/reviewed-preprints/84553?utm_source=mastodon&utm_medium=social&utm_campaign=organic

This sandwich-like structure of columns gives strength and flexibility to the shell of a #brachiopod and has helped researchers understand the evolution of these distinctive structures during the Cambrian explosion. #Evolution #ReviewedPreprint #12DaysOfeLife https://elifesciences.org/reviewed-preprints/88855?utm_source=mastodon&utm_medium=social&utm_campaign=organic_12Days

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint #Neuroscience https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint #Neuroscience https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint #Neuroscience https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint #Neuroscience https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint #Neuroscience https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint #Neuroscience https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint #Neuroscience https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint #Neuroscience https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic

What are the risks of an #MRI for people with #orthopaedic implants? A new method in this #ReviewedPreprint will help clinicians evaluate the safety of #MagneticResonance in patients. https://elifesciences.org/reviewed-preprints/90440?utm_source=mastodon&utm_medium=social&utm_campaign=organic

What are the risks of an #MRI for people with #orthopaedic implants? A new method in this #ReviewedPreprint will help clinicians evaluate the safety of #MagneticResonance in patients. https://elifesciences.org/reviewed-preprints/90440?utm_source=mastodon&utm_medium=social&utm_campaign=organic

What are the risks of an #MRI for people with #orthopaedic implants? A new method in this #ReviewedPreprint will help clinicians evaluate the safety of #MagneticResonance in patients. https://elifesciences.org/reviewed-preprints/90440?utm_source=mastodon&utm_medium=social&utm_campaign=organic

What are the risks of an #MRI for people with #orthopaedic implants? A new method in this #ReviewedPreprint will help clinicians evaluate the safety of #MagneticResonance in patients. https://elifesciences.org/reviewed-preprints/90440?utm_source=mastodon&utm_medium=social&utm_campaign=organic

What are the risks of an #MRI for people with #orthopaedic implants? A new method in this #ReviewedPreprint will help clinicians evaluate the safety of #MagneticResonance in patients. https://elifesciences.org/reviewed-preprints/90440?utm_source=mastodon&utm_medium=social&utm_campaign=organic

#Neutrophils swell to speed up migration. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/90551?utm_source=twitter&utm_medium=social&utm_campaign=organic

With more data, new protein biomarkers identified in a new #ReviewedPreprint could be utilised for the identification of women at risk for #preeclampsia prior to the onset of the disease. #Medicine #Pregnancy https://elifesciences.org/reviewed-preprints/88841?utm_source=mastodon&utm_medium=social&utm_campaign=organic

New #microscopy technology enables #nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint https://elifesciences.org/reviewed-preprints/91979?utm_source=mastodon&utm_medium=social&utm_campaign=organic