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#pluripotency — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #pluripotency, aggregated by home.social.

  1. "While endogenous #retroviruses (ERVs) are essential for early development..precise role..remains mysterious. Using cutting-edge #genetic & biochemical techniques in mice, we identify MERVL-gag, a retroviral protein, as a crucial modulator of pluripotent factors OCT4 & SOX2 during lineage specification. MERVL-gag tightly operates with URI, a prefoldin #protein that concurs with #pluripotency bias in mouse #blastomeres..required for totipotency-to-pluripotency transition"

    science.org/doi/10.1126/sciadv

  2. "While endogenous #retroviruses (ERVs) are essential for early development..precise role..remains mysterious. Using cutting-edge #genetic & biochemical techniques in mice, we identify MERVL-gag, a retroviral protein, as a crucial modulator of pluripotent factors OCT4 & SOX2 during lineage specification. MERVL-gag tightly operates with URI, a prefoldin #protein that concurs with #pluripotency bias in mouse #blastomeres..required for totipotency-to-pluripotency transition"

    science.org/doi/10.1126/sciadv

  3. "While endogenous #retroviruses (ERVs) are essential for early development..precise role..remains mysterious. Using cutting-edge #genetic & biochemical techniques in mice, we identify MERVL-gag, a retroviral protein, as a crucial modulator of pluripotent factors OCT4 & SOX2 during lineage specification. MERVL-gag tightly operates with URI, a prefoldin #protein that concurs with #pluripotency bias in mouse #blastomeres..required for totipotency-to-pluripotency transition"

    science.org/doi/10.1126/sciadv

  4. "While endogenous #retroviruses (ERVs) are essential for early development..precise role..remains mysterious. Using cutting-edge #genetic & biochemical techniques in mice, we identify MERVL-gag, a retroviral protein, as a crucial modulator of pluripotent factors OCT4 & SOX2 during lineage specification. MERVL-gag tightly operates with URI, a prefoldin #protein that concurs with #pluripotency bias in mouse #blastomeres..required for totipotency-to-pluripotency transition"

    science.org/doi/10.1126/sciadv

  5. "While endogenous #retroviruses (ERVs) are essential for early development..precise role..remains mysterious. Using cutting-edge #genetic & biochemical techniques in mice, we identify MERVL-gag, a retroviral protein, as a crucial modulator of pluripotent factors OCT4 & SOX2 during lineage specification. MERVL-gag tightly operates with URI, a prefoldin #protein that concurs with #pluripotency bias in mouse #blastomeres..required for totipotency-to-pluripotency transition"

    science.org/doi/10.1126/sciadv

  6. "Here, we demonstrate that the #midbody (MB) matrix is the site of ribonucleoprotein assembly and is enriched in mRNAs that encode proteins involved in cell fate, #oncogenesis, and #pluripotency, which we are calling the MB granule. Both MBs and post-abscission MBRs are sites of spatiotemporally regulated translation, which is initiated when nascent daughter cells re-enter G1 and continues after #extracellular release"

    sciencedirect.com/science/arti

  7. A study of the role of #Nanog and Nodal in establishing pluripotency in an #amphibian, the #axolotl, indicates that the gene regulatory networks underlying #pluripotency are conserved and provided the basis for the evolution of #mesoderm #PLOSBiology plos.io/3qOmcmG

  8. Hi #ScienceMastodon 🔬 !

    #introduction

    I'm a final year #PhD student from Richard Meehan's lab at MRC HGU, University of Edinburgh 🏴󠁧󠁢󠁳󠁣󠁴󠁿 .

    In my project I'm investigating what roles #DNAmethylation and #polycomb play in #pluripotency and differentiation of mouse embryonic #stemcells 🐭 🧬

    I'm a wet-lab biologist by training but I've been learning lots of #bioinformatics recently and I'm hoping to do a #postdoc in Europe where I can combine both skillsets 🇪🇺

  9. Hi Mastodon!
    I’m a Academic Clinical Lecturer in #genetics at Imperial College London and an MRC Investigator in the #epigenetics section at the London Institute of Medical Sciences studying #germline and #pluripotency. We also have a growing interest in #infertility and developmental disorders #raredisease. Post mainly about #Science #Squash #Scotland #Sport. Also a bit #Sweary - sorry mum. Still on Twitter interested to see what happens here though

  10. Hi #Sciencemastodon. #Introduction.

    I am an #educator in #Microbiology at present.
    I have researched on #HumanImmunodeficiencyVirus and on #HepatitisBVirus. In the context of #HepatitisBvirus, I analyzed deletion mutants and their effects on #virus #biology. I further worked on #stemness in the context of #breastcancer. I studied the relation between #tumorsuppressors and #oncogenes and #pluripotency factors. I will soon be moving to #research on #HepatitisBvirus and #livercancer

  11. Hi #Sciencemastodon. #Introduction.

    I am an #educator in #Microbiology at present.
    I have researched on #HumanImmunodeficiencyVirus and on #HepatitisBVirus. In the context of #HepatitisBvirus, I analyzed deletion mutants and their effects on #virus #biology. I further worked on #stemness in the context of #breastcancer. I studied the relation between #tumorsuppressors and #oncogenes and #pluripotency factors. I will soon be moving to #research on #HepatitisBvirus and #livercancer

  12. Hi #Sciencemastodon. #Introduction.

    I am an #educator in #Microbiology at present.
    I have researched on #HumanImmunodeficiencyVirus and on #HepatitisBVirus. In the context of #HepatitisBvirus, I analyzed deletion mutants and their effects on #virus #biology. I further worked on #stemness in the context of #breastcancer. I studied the relation between #tumorsuppressors and #oncogenes and #pluripotency factors. I will soon be moving to #research on #HepatitisBvirus and #livercancer

  13. Hi #Sciencemastodon. #Introduction.

    I am an #educator in #Microbiology at present.
    I have researched on #HumanImmunodeficiencyVirus and on #HepatitisBVirus. In the context of #HepatitisBvirus, I analyzed deletion mutants and their effects on #virus #biology. I further worked on #stemness in the context of #breastcancer. I studied the relation between #tumorsuppressors and #oncogenes and #pluripotency factors. I will soon be moving to #research on #HepatitisBvirus and #livercancer

  14. Hi #Sciencemastodon. #Introduction.

    I am an #educator in #Microbiology at present.
    I have researched on #HumanImmunodeficiencyVirus and on #HepatitisBVirus. In the context of #HepatitisBvirus, I analyzed deletion mutants and their effects on #virus #biology. I further worked on #stemness in the context of #breastcancer. I studied the relation between #tumorsuppressors and #oncogenes and #pluripotency factors. I will soon be moving to #research on #HepatitisBvirus and #livercancer

  15. 🍽️ Thanks to ERC-funding, researchers @LSI_Exeter have developed #stemcells lines from pigs, sheep and cattle, laying the groundwork for the manufacture of cultured meat.

    Read more 👉 bit.ly/3PJ98Y2
    #pluripotency #livestock #biotechnology

    @CORDIS_EU @UniofExeter

    🐦🔗: nitter.eu/ERC_Research/status/