#polycomb — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #polycomb, aggregated by home.social.
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"These data show that a reversible depletion of #Polycomb proteins can induce cancer in the absence of driver mutations, suggesting that tumours can emerge through #epigenetic dysregulation leading to inheritance of altered cell fates"
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"These data show that a reversible depletion of #Polycomb proteins can induce cancer in the absence of driver mutations, suggesting that tumours can emerge through #epigenetic dysregulation leading to inheritance of altered cell fates"
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"These data show that a reversible depletion of #Polycomb proteins can induce cancer in the absence of driver mutations, suggesting that tumours can emerge through #epigenetic dysregulation leading to inheritance of altered cell fates"
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"These data show that a reversible depletion of #Polycomb proteins can induce cancer in the absence of driver mutations, suggesting that tumours can emerge through #epigenetic dysregulation leading to inheritance of altered cell fates"
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"These data show that a reversible depletion of #Polycomb proteins can induce cancer in the absence of driver mutations, suggesting that tumours can emerge through #epigenetic dysregulation leading to inheritance of altered cell fates"
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A nice paper is the best way to start the year: here evidence that the #Polycomb PRC1 complex is required to maintain the undifferentiated state of adult spermatogonia stem cells.
Nucleic Acids Res. 2023 Dec 24
doi: 10.1093/nar/gkad1203.PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation
Happy New Year: Peace, Joy, Health and Love for everybody !
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A nice paper is the best way to start the year: here evidence that the #Polycomb PRC1 complex is required to maintain the undifferentiated state of adult spermatogonia stem cells.
Nucleic Acids Res. 2023 Dec 24
doi: 10.1093/nar/gkad1203.PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation
Happy New Year: Peace, Joy, Health and Love for everybody !
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A nice paper is the best way to start the year: here evidence that the #Polycomb PRC1 complex is required to maintain the undifferentiated state of adult spermatogonia stem cells.
Nucleic Acids Res. 2023 Dec 24
doi: 10.1093/nar/gkad1203.PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation
Happy New Year: Peace, Joy, Health and Love for everybody !
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A nice paper is the best way to start the year: here evidence that the #Polycomb PRC1 complex is required to maintain the undifferentiated state of adult spermatogonia stem cells.
Nucleic Acids Res. 2023 Dec 24
doi: 10.1093/nar/gkad1203.PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation
Happy New Year: Peace, Joy, Health and Love for everybody !
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A nice paper is the best way to start the year: here evidence that the #Polycomb PRC1 complex is required to maintain the undifferentiated state of adult spermatogonia stem cells.
Nucleic Acids Res. 2023 Dec 24
doi: 10.1093/nar/gkad1203.PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation
Happy New Year: Peace, Joy, Health and Love for everybody !
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In the paper below, exciting discussion on the evolution of #Polycomb complexes:
Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1
Commun Biol. 2023 Nov 10;6(1):1144.
doi: 10.1038/s42003-023-05501-x -
In the paper below, exciting discussion on the evolution of #Polycomb complexes:
Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1
Commun Biol. 2023 Nov 10;6(1):1144.
doi: 10.1038/s42003-023-05501-x -
In the paper below, exciting discussion on the evolution of #Polycomb complexes:
Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1
Commun Biol. 2023 Nov 10;6(1):1144.
doi: 10.1038/s42003-023-05501-x -
In the paper below, exciting discussion on the evolution of #Polycomb complexes:
Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1
Commun Biol. 2023 Nov 10;6(1):1144.
doi: 10.1038/s42003-023-05501-x -
In the paper below, exciting discussion on the evolution of #Polycomb complexes:
Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1
Commun Biol. 2023 Nov 10;6(1):1144.
doi: 10.1038/s42003-023-05501-x -
Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry
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Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry
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Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry
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Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry
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Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry
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A universal #aging clock based on #DNA methylation profiles and linked to #Polycomb proteins:
doi: 10.1038/s43587-023-00462-6.
Universal DNA methylation age across mammalian tissues
The authors conclude: Our findings offer new evidence suggesting that aging is evolutionarily conserved and intertwined with developmental processes across all mammals.
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A universal #aging clock based on #DNA methylation profiles and linked to #Polycomb proteins:
doi: 10.1038/s43587-023-00462-6.
Universal DNA methylation age across mammalian tissues
The authors conclude: Our findings offer new evidence suggesting that aging is evolutionarily conserved and intertwined with developmental processes across all mammals.
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A universal #aging clock based on #DNA methylation profiles and linked to #Polycomb proteins:
doi: 10.1038/s43587-023-00462-6.
Universal DNA methylation age across mammalian tissues
The authors conclude: Our findings offer new evidence suggesting that aging is evolutionarily conserved and intertwined with developmental processes across all mammals.
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A universal #aging clock based on #DNA methylation profiles and linked to #Polycomb proteins:
doi: 10.1038/s43587-023-00462-6.
Universal DNA methylation age across mammalian tissues
The authors conclude: Our findings offer new evidence suggesting that aging is evolutionarily conserved and intertwined with developmental processes across all mammals.
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A universal #aging clock based on #DNA methylation profiles and linked to #Polycomb proteins:
doi: 10.1038/s43587-023-00462-6.
Universal DNA methylation age across mammalian tissues
The authors conclude: Our findings offer new evidence suggesting that aging is evolutionarily conserved and intertwined with developmental processes across all mammals.
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A new study from Yuri Schwartz's lab:
#Polycomb proteins translate #histone #methylation to #chromatin
foldingDOI: 10.1016/j.jbc.2023.105080
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A new study from Yuri Schwartz's lab:
#Polycomb proteins translate #histone #methylation to #chromatin
foldingDOI: 10.1016/j.jbc.2023.105080
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A new study from Yuri Schwartz's lab:
#Polycomb proteins translate #histone #methylation to #chromatin
foldingDOI: 10.1016/j.jbc.2023.105080
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A new study from Yuri Schwartz's lab:
#Polycomb proteins translate #histone #methylation to #chromatin
foldingDOI: 10.1016/j.jbc.2023.105080
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A new study from Yuri Schwartz's lab:
#Polycomb proteins translate #histone #methylation to #chromatin
foldingDOI: 10.1016/j.jbc.2023.105080
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Exciting work from Wendy Bickmore's lab on the relation between phase separation and #Polycomb:
Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops
doi: 10.26508/lsa.202302101.
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Exciting work from Wendy Bickmore's lab on the relation between phase separation and #Polycomb:
Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops
doi: 10.26508/lsa.202302101.
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Exciting work from Wendy Bickmore's lab on the relation between phase separation and #Polycomb:
Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops
doi: 10.26508/lsa.202302101.
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Exciting work from Wendy Bickmore's lab on the relation between phase separation and #Polycomb:
Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops
doi: 10.26508/lsa.202302101.
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Exciting work from Wendy Bickmore's lab on the relation between phase separation and #Polycomb:
Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops
doi: 10.26508/lsa.202302101.
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Here the authors identify a protein that might promote cancer by inhibiting #Polycomb PRC2-mediated deposition of H3K27me3.
NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression
DOI: 10.1101/2023.06.13.544862
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Here the authors identify a protein that might promote cancer by inhibiting #Polycomb PRC2-mediated deposition of H3K27me3.
NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression
DOI: 10.1101/2023.06.13.544862
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Here the authors identify a protein that might promote cancer by inhibiting #Polycomb PRC2-mediated deposition of H3K27me3.
NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression
DOI: 10.1101/2023.06.13.544862
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Here the authors identify a protein that might promote cancer by inhibiting #Polycomb PRC2-mediated deposition of H3K27me3.
NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression
DOI: 10.1101/2023.06.13.544862
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Here the authors identify a protein that might promote cancer by inhibiting #Polycomb PRC2-mediated deposition of H3K27me3.
NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression
DOI: 10.1101/2023.06.13.544862
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A famous #Polycomb protein with roles in gene silencing but also activation!
BMI1 fine-tunes gene repression and activation to safeguard undifferentiated spermatogonia fate
Front. Cell Dev. Biol., Volume 11 - 2023
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A famous #Polycomb protein with roles in gene silencing but also activation!
BMI1 fine-tunes gene repression and activation to safeguard undifferentiated spermatogonia fate
Front. Cell Dev. Biol., Volume 11 - 2023
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A famous #Polycomb protein with roles in gene silencing but also activation!
BMI1 fine-tunes gene repression and activation to safeguard undifferentiated spermatogonia fate
Front. Cell Dev. Biol., Volume 11 - 2023
-
A famous #Polycomb protein with roles in gene silencing but also activation!
BMI1 fine-tunes gene repression and activation to safeguard undifferentiated spermatogonia fate
Front. Cell Dev. Biol., Volume 11 - 2023
-
A famous #Polycomb protein with roles in gene silencing but also activation!
BMI1 fine-tunes gene repression and activation to safeguard undifferentiated spermatogonia fate
Front. Cell Dev. Biol., Volume 11 - 2023
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Here the identification of yet another recruiter of #Polycomb group proteins in #Drosophila, great work from the Erokhin, Chetverina and Kassis labs !
Crol contributes to PRE-mediated repression and Polycomb group proteins recruitment in Drosophila, Nucleic Acids Research, 2023; gkad336, https://doi.org/10.1093/nar/gkad336
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Here the identification of yet another recruiter of #Polycomb group proteins in #Drosophila, great work from the Erokhin, Chetverina and Kassis labs !
Crol contributes to PRE-mediated repression and Polycomb group proteins recruitment in Drosophila, Nucleic Acids Research, 2023; gkad336, https://doi.org/10.1093/nar/gkad336
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Here the identification of yet another recruiter of #Polycomb group proteins in #Drosophila, great work from the Erokhin, Chetverina and Kassis labs !
Crol contributes to PRE-mediated repression and Polycomb group proteins recruitment in Drosophila, Nucleic Acids Research, 2023; gkad336, https://doi.org/10.1093/nar/gkad336
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Here the identification of yet another recruiter of #Polycomb group proteins in #Drosophila, great work from the Erokhin, Chetverina and Kassis labs !
Crol contributes to PRE-mediated repression and Polycomb group proteins recruitment in Drosophila, Nucleic Acids Research, 2023; gkad336, https://doi.org/10.1093/nar/gkad336
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Here the identification of yet another recruiter of #Polycomb group proteins in #Drosophila, great work from the Erokhin, Chetverina and Kassis labs !
Crol contributes to PRE-mediated repression and Polycomb group proteins recruitment in Drosophila, Nucleic Acids Research, 2023; gkad336, https://doi.org/10.1093/nar/gkad336
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An unexpected twist between #Polycomb and #Notch signaling: a PRC2 enzyme induces Notch signaling using non-enzymatic functions.
Feng, X., Wang, A.H., Juan, A.H., Ko, K.D., Jiang, K., Riparini, G., Ciuffoli, V., Kaba, A., Lopez, C., Naz, F., et al. (2023). Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling. Dev Cell. 10.1016/j.devcel.2023.04.005.
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An unexpected twist between #Polycomb and #Notch signaling: a PRC2 enzyme induces Notch signaling using non-enzymatic functions.
Feng, X., Wang, A.H., Juan, A.H., Ko, K.D., Jiang, K., Riparini, G., Ciuffoli, V., Kaba, A., Lopez, C., Naz, F., et al. (2023). Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling. Dev Cell. 10.1016/j.devcel.2023.04.005.
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An unexpected twist between #Polycomb and #Notch signaling: a PRC2 enzyme induces Notch signaling using non-enzymatic functions.
Feng, X., Wang, A.H., Juan, A.H., Ko, K.D., Jiang, K., Riparini, G., Ciuffoli, V., Kaba, A., Lopez, C., Naz, F., et al. (2023). Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling. Dev Cell. 10.1016/j.devcel.2023.04.005.
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An unexpected twist between #Polycomb and #Notch signaling: a PRC2 enzyme induces Notch signaling using non-enzymatic functions.
Feng, X., Wang, A.H., Juan, A.H., Ko, K.D., Jiang, K., Riparini, G., Ciuffoli, V., Kaba, A., Lopez, C., Naz, F., et al. (2023). Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling. Dev Cell. 10.1016/j.devcel.2023.04.005.
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An unexpected twist between #Polycomb and #Notch signaling: a PRC2 enzyme induces Notch signaling using non-enzymatic functions.
Feng, X., Wang, A.H., Juan, A.H., Ko, K.D., Jiang, K., Riparini, G., Ciuffoli, V., Kaba, A., Lopez, C., Naz, F., et al. (2023). Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling. Dev Cell. 10.1016/j.devcel.2023.04.005.