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#cgrp — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cgrp, aggregated by home.social.

  1. TheGoodbyeGirl 🇬🇧🇮🇪 @[email protected] ·

    It was Ajovy day today & oof! It was a spicy one 🤣 good job it's an auto injector & it's quick.

    Plus it's only once a month.

    #ChronicMigraine #Migraine #Ajovy #CGRP

    #chronicmigraine #migraine #ajovy #cgrp
  2. TheGoodbyeGirl 🇬🇧🇮🇪 @[email protected] ·

    It was Ajovy day today & oof! It was a spicy one 🤣 good job it's an auto injector & it's quick.

    Plus it's only once a month.

    #ChronicMigraine #Migraine #Ajovy #CGRP

    #cgrp #ajovy #migraine #chronicmigraine
  3. TheGoodbyeGirl 🇬🇧🇮🇪 @[email protected] ·

    It was Ajovy day today & oof! It was a spicy one 🤣 good job it's an auto injector & it's quick.

    Plus it's only once a month.

    #ChronicMigraine #Migraine #Ajovy #CGRP

    #chronicmigraine #migraine #ajovy #cgrp
  4. Ireland @[email protected] ·

    europesays.com/ie/178572/ Histamine plasma levels from dietary histidine/histamine intake correlate with CGRP in trigeminal tissues | The Journal of Headache and Pain #CalcitoninGeneRelatedPeptide #CGRP #Éire #headache #Health #HistamineIntolerance #IE #InternalMedicine #Ireland #migraine #neurology #PainMedicine #TrigeminalSensitization

    #trigeminalsensitization #painmedicine #neurology #migraine #ireland #internalmedicine
  5. 卡拉今天看了什麼 @[email protected] ·

    Migraine is more than a headache – a rethink offers hope | Hacker News

    Link
    📌 Summary: 本文探討了偏頭痛的最新研究進展及新型藥物的潛力。特別是 gepants 類藥物的出現，讓許多患者，包括 Andrea West，在持續多年的偏頭痛中找到了解決方案。文中提到，過去對偏頭痛的理解主要以血管和心理問題為主，現在的研究強調偏頭痛的生物學機制，展示出更全面的病因。此外，科學家們正尋找偏頭痛發作的觸發因素，從基本的神經系統到環境因素都可能影響病情。

    🎯 Key Points:
    - Gepants 是新一代偏頭痛藥物，已在英國獲準使用。
    - 偏頭痛的症狀多樣，且並不僅限於痛苦的頭痛，而是包括腦霧、感光和疲勞等。
    - 新研究顯示，偏頭痛的產生與大腦活動的改變及特定生物標記有關。
    - 需要更全面的研究來瞭解偏頭痛的觸發機制，以制定有效治療策略。
    - 預防和管理偏頭痛的藥物，如 CGRP 抑制劑，對某些患者效果顯著，但仍然存在適應性與普及性的挑戰。

    🔖 Keywords: #偏頭痛 #Gepants #CGRP #生物學機制 #新藥研究

    #偏頭痛 #gepants #cgrp #生物學機制 #新藥研究
  6. AutisticMumTo3 @[email protected] ·

    Patients in England to be offered daily pill that can halve migraine frequency | National Institute for Health and Care Excellence | The Guardian
    theguardian.com/society/2024/a

    #Migraine
    #PillForMigraines
    #MigrainePrevention
    #NHSApprovedMedicine
    #NICE
    #NICEApproved
    #Atogepant
    #Aquipta
    #AbbVie
    #CalcitoninGeneRelatedPeptide
    #CGRP
    #ChronicMigraine
    #EpisodicMigraine
    #MigraineTrust
    #ScottishMedicinesConsortium

    #migraine #pillformigraines #migraineprevention #nhsapprovedmedicine #nice #niceapproved
  7. AutisticMumTo3 @[email protected] ·

    Patients in England to be offered daily pill that can halve migraine frequency | National Institute for Health and Care Excellence | The Guardian
    theguardian.com/society/2024/a

    #Migraine
    #PillForMigraines
    #MigrainePrevention
    #NHSApprovedMedicine
    #NICE
    #NICEApproved
    #Atogepant
    #Aquipta
    #AbbVie
    #CalcitoninGeneRelatedPeptide
    #CGRP
    #ChronicMigraine
    #EpisodicMigraine
    #MigraineTrust
    #ScottishMedicinesConsortium

    #migraine #pillformigraines #migraineprevention #nhsapprovedmedicine #nice #niceapproved
  8. AutisticMumTo3 @[email protected] ·

    Patients in England to be offered daily pill that can halve migraine frequency | National Institute for Health and Care Excellence | The Guardian
    theguardian.com/society/2024/a

    #Migraine
    #PillForMigraines
    #MigrainePrevention
    #NHSApprovedMedicine
    #NICE
    #NICEApproved
    #Atogepant
    #Aquipta
    #AbbVie
    #CalcitoninGeneRelatedPeptide
    #CGRP
    #ChronicMigraine
    #EpisodicMigraine
    #MigraineTrust
    #ScottishMedicinesConsortium

    #migraine #pillformigraines #migraineprevention #nhsapprovedmedicine #nice #niceapproved
  9. AutisticMumTo3 @[email protected] ·

    Patients in England to be offered daily pill that can halve migraine frequency | National Institute for Health and Care Excellence | The Guardian
    theguardian.com/society/2024/a

    #Migraine
    #PillForMigraines
    #MigrainePrevention
    #NHSApprovedMedicine
    #NICE
    #NICEApproved
    #Atogepant
    #Aquipta
    #AbbVie
    #CalcitoninGeneRelatedPeptide
    #CGRP
    #ChronicMigraine
    #EpisodicMigraine
    #MigraineTrust
    #ScottishMedicinesConsortium

    #scottishmedicinesconsortium #migrainetrust #episodicmigraine #chronicmigraine #cgrp #calcitoningenerelatedpeptide
  10. AutisticMumTo3 @[email protected] ·

    Patients in England to be offered daily pill that can halve migraine frequency | National Institute for Health and Care Excellence | The Guardian
    theguardian.com/society/2024/a

    #Migraine
    #PillForMigraines
    #MigrainePrevention
    #NHSApprovedMedicine
    #NICE
    #NICEApproved
    #Atogepant
    #Aquipta
    #AbbVie
    #CalcitoninGeneRelatedPeptide
    #CGRP
    #ChronicMigraine
    #EpisodicMigraine
    #MigraineTrust
    #ScottishMedicinesConsortium

    #migraine #pillformigraines #migraineprevention #nhsapprovedmedicine #nice #niceapproved
  11. DrBob, 🧠 Mechanic @[email protected] ·

    Migraine Update: PACAP pathophysiology

    “In contrast to CGRP, in the periphery of the cranium, PACAP is mainly expressed in parasympathetic neurons with a much smaller trigeminal distribution than #CGRP in rats and humans. The predominant site of PACAP expression in rats and humans is the extracranial parasympathetic sphenopalatine ganglion, which also contains #PACAP receptors”

    #migraine #neurology #headache
    thejournalofheadacheandpain.bi

    #cgrp #pacap #migraine #neurology #headache
  12. DrBob, 🧠 Mechanic @[email protected] ·

    Migraine Update: PACAP pathophysiology

    “In contrast to CGRP, in the periphery of the cranium, PACAP is mainly expressed in parasympathetic neurons with a much smaller trigeminal distribution than #CGRP in rats and humans. The predominant site of PACAP expression in rats and humans is the extracranial parasympathetic sphenopalatine ganglion, which also contains #PACAP receptors”

    #migraine #neurology #headache
    thejournalofheadacheandpain.bi

    #cgrp #pacap #migraine #neurology #headache
  13. DrBob, 🧠 Mechanic @[email protected] ·

    Migraine Update: PACAP pathophysiology

    “In contrast to CGRP, in the periphery of the cranium, PACAP is mainly expressed in parasympathetic neurons with a much smaller trigeminal distribution than #CGRP in rats and humans. The predominant site of PACAP expression in rats and humans is the extracranial parasympathetic sphenopalatine ganglion, which also contains #PACAP receptors”

    #migraine #neurology #headache
    thejournalofheadacheandpain.bi

    #cgrp #pacap #migraine #neurology #headache
  14. DrBob, 🧠 Mechanic @[email protected] ·

    Migraine Update: PACAP pathophysiology

    “In contrast to CGRP, in the periphery of the cranium, PACAP is mainly expressed in parasympathetic neurons with a much smaller trigeminal distribution than #CGRP in rats and humans. The predominant site of PACAP expression in rats and humans is the extracranial parasympathetic sphenopalatine ganglion, which also contains #PACAP receptors”

    #migraine #neurology #headache
    thejournalofheadacheandpain.bi

    #headache #neurology #migraine #pacap #cgrp
  15. DrBob, 🧠 Mechanic @[email protected] ·

    Migraine Update: PACAP pathophysiology

    “In contrast to CGRP, in the periphery of the cranium, PACAP is mainly expressed in parasympathetic neurons with a much smaller trigeminal distribution than #CGRP in rats and humans. The predominant site of PACAP expression in rats and humans is the extracranial parasympathetic sphenopalatine ganglion, which also contains #PACAP receptors”

    #migraine #neurology #headache
    thejournalofheadacheandpain.bi

    #cgrp #pacap #migraine #neurology #headache
  16. DrBob, 🧠 Mechanic @[email protected] ·

    @janetlogan Triptan or #CGRP agent? #Sumatriptan or #Nurtec are good options for #migrine.

    #cgrp #sumatriptan #nurtec #migrine
  17. DrBob, 🧠 Mechanic @[email protected] ·

    @janetlogan Triptan or #CGRP agent? #Sumatriptan or #Nurtec are good options for #migrine.

    #cgrp #sumatriptan #nurtec #migrine
  18. DrBob, 🧠 Mechanic @[email protected] ·

    @janetlogan Triptan or #CGRP agent? #Sumatriptan or #Nurtec are good options for #migrine.

    #cgrp #sumatriptan #nurtec #migrine
  19. DrBob, 🧠 Mechanic @[email protected] ·

    @janetlogan Triptan or #CGRP agent? #Sumatriptan or #Nurtec are good options for #migrine.

    #migrine #nurtec #sumatriptan #cgrp
  20. DrBob, 🧠 Mechanic @[email protected] ·

    @janetlogan Triptan or #CGRP agent? #Sumatriptan or #Nurtec are good options for #migrine.

    #cgrp #sumatriptan #nurtec #migrine
  21. Rhyothemis @[email protected] ·

    research article (2019):
    Puerarin suppresses TRPV1, calcitonin gene-related peptide and substance P to prevent paclitaxel-induced peripheral neuropathic pain in rats
    doi.org/10.1177/03331024177485
    ~
    Puerarin is a natural product found in kudzu root. Kudzu root is used to make Japanese kuzu noodles - don't know how much puerarin is in kuzu starch, but it's used traditionally as a digestive aid.

    #2badItsPaywalled #CGRP #TRPV1 #NaturalProducts #FunctionalFoods
    #puerarin #kuzu #neuropathy #ChronicPain

    #2baditspaywalled #cgrp #trpv1 #naturalproducts #functionalfoods #puerarin
  22. Rhyothemis @[email protected] ·

    research article (2019):
    Puerarin suppresses TRPV1, calcitonin gene-related peptide and substance P to prevent paclitaxel-induced peripheral neuropathic pain in rats
    doi.org/10.1177/03331024177485
    ~
    Puerarin is a natural product found in kudzu root. Kudzu root is used to make Japanese kuzu noodles - don't know how much puerarin is in kuzu starch, but it's used traditionally as a digestive aid.

    #2badItsPaywalled #CGRP #TRPV1 #NaturalProducts #FunctionalFoods
    #puerarin #kuzu #neuropathy #ChronicPain

    #2baditspaywalled #cgrp #trpv1 #naturalproducts #functionalfoods #puerarin
  23. Rhyothemis @[email protected] ·

    research article (2019):
    Puerarin suppresses TRPV1, calcitonin gene-related peptide and substance P to prevent paclitaxel-induced peripheral neuropathic pain in rats
    doi.org/10.1177/03331024177485
    ~
    Puerarin is a natural product found in kudzu root. Kudzu root is used to make Japanese kuzu noodles - don't know how much puerarin is in kuzu starch, but it's used traditionally as a digestive aid.

    #2badItsPaywalled #CGRP #TRPV1 #NaturalProducts #FunctionalFoods
    #puerarin #kuzu #neuropathy #ChronicPain

    #chronicpain #neuropathy #kuzu #puerarin #functionalfoods #naturalproducts
  24. DrBob, 🧠 Mechanic @[email protected] ·

    New nasal spray migraine medication —Zavegepant — coming out this summer.

    “The Food and Drug Administration has approved a Pfizer nasal spray for treatment of #migraine that uses a different therapy from other nasal products on the market for severe headache pain, the company said on Friday.”

    #cgrp #ZAVZPRET
    nyti.ms/3Jvbl8a

    #migraine #cgrp #zavzpret
  25. DrBob, 🧠 Mechanic @[email protected] ·

    New nasal spray migraine medication —Zavegepant — coming out this summer.

    “The Food and Drug Administration has approved a Pfizer nasal spray for treatment of #migraine that uses a different therapy from other nasal products on the market for severe headache pain, the company said on Friday.”

    #cgrp #ZAVZPRET
    nyti.ms/3Jvbl8a

    #migraine #cgrp #zavzpret
  26. Dr. Robert M Flight @[email protected] ·
    CW: Gut-Brain Health and Pain Medications

    @migrainechat Huh. That's interesting.

    I saw a GI specialist last week, and it seems that NSAIDs also block signals around mucus production, which also contributes to lack of mucus production.

    Will be interesting to see followups for all the #migraine patients switching to #CGRP inhibitors the past few years.

    #migraine #cgrp
  27. Beth Morton | MigraineChat @[email protected] ·
    CW: Gut-Brain Health and Pain Medications

    The tl;dr:
    - In mice, gut mucosal producing cells contain receptors activated by #CGRP, a neuropeptide released in response to pain.
    - Blocking those receptors might mean the gut won’t get the “message” to make more mucus, necessary for gut health.
    - Anti-CGRP medications are used to block CGRP (receptors or the molecule itself) in #migraine, to prevent migraine attacks.

    #MigraineChat
    medscape.com/viewarticle/98441

    #cgrp #migraine #migrainechat
  28. kate @[email protected] ·

    Errr this is beyond my brain's capacity to process, but sharing for those on #migraine meds that are the #CGRP type. In the US they're meds like #Ajovy #Emgality etc

    cell.com/cell/fulltext/S0092-8

    #migraine #cgrp #ajovy #emgality
  29. Sanku @[email protected] ·

    Remboursez les anticorps anti-CGRP aux patients atteints de migraine sévère et réfractaire

    change.org/p/olivier-v%C3%A9ra

    #Migraine #Pétition #Migraine #CGRP #Handicap #droit #santépublique #olivierveran

    #olivierveran #santépublique #droit #handicap #cgrp #pétition