#cgrp — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #cgrp, aggregated by home.social.
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Migraine is more than a headache – a rethink offers hope | Hacker News
Link
📌 Summary: 本文探討了偏頭痛的最新研究進展及新型藥物的潛力。特別是 gepants 類藥物的出現，讓許多患者，包括 Andrea West，在持續多年的偏頭痛中找到了解決方案。文中提到，過去對偏頭痛的理解主要以血管和心理問題為主，現在的研究強調偏頭痛的生物學機制，展示出更全面的病因。此外，科學家們正尋找偏頭痛發作的觸發因素，從基本的神經系統到環境因素都可能影響病情。
🎯 Key Points:
- Gepants 是新一代偏頭痛藥物，已在英國獲準使用。
- 偏頭痛的症狀多樣，且並不僅限於痛苦的頭痛，而是包括腦霧、感光和疲勞等。
- 新研究顯示，偏頭痛的產生與大腦活動的改變及特定生物標記有關。
- 需要更全面的研究來瞭解偏頭痛的觸發機制，以制定有效治療策略。
- 預防和管理偏頭痛的藥物，如 CGRP 抑制劑，對某些患者效果顯著，但仍然存在適應性與普及性的挑戰。
🔖 Keywords: #偏頭痛 #Gepants #CGRP #生物學機制 #新藥研究 -
Patients in England to be offered daily pill that can halve migraine frequency | National Institute for Health and Care Excellence | The Guardian
https://www.theguardian.com/society/2024/apr/11/patients-in-england-to-be-offered-daily-pill-that-can-halve-migraine-frequency#Migraine
#PillForMigraines
#MigrainePrevention
#NHSApprovedMedicine
#NICE
#NICEApproved
#Atogepant
#Aquipta
#AbbVie
#CalcitoninGeneRelatedPeptide
#CGRP
#ChronicMigraine
#EpisodicMigraine
#MigraineTrust
#ScottishMedicinesConsortium -
CW: Gut-Brain Health and Pain Medications
@migrainechat Huh. That's interesting.
I saw a GI specialist last week, and it seems that NSAIDs also block signals around mucus production, which also contributes to lack of mucus production.
Will be interesting to see followups for all the #migraine patients switching to #CGRP inhibitors the past few years.
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CW: Gut-Brain Health and Pain Medications
The tl;dr:
- In mice, gut mucosal producing cells contain receptors activated by #CGRP, a neuropeptide released in response to pain.
- Blocking those receptors might mean the gut won’t get the “message” to make more mucus, necessary for gut health.
- Anti-CGRP medications are used to block CGRP (receptors or the molecule itself) in #migraine, to prevent migraine attacks. -
Remboursez les anticorps anti-CGRP aux patients atteints de migraine sévère et réfractaire
#Migraine #Pétition #Migraine #CGRP #Handicap #droit #santépublique #olivierveran
