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#cgrp — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cgrp, aggregated by home.social.

  1. Migraine is more than a headache – a rethink offers hope | Hacker News

    Link
    📌 Summary: 本文探討了偏頭痛的最新研究進展及新型藥物的潛力。特別是 gepants 類藥物的出現,讓許多患者,包括 Andrea West,在持續多年的偏頭痛中找到了解決方案。文中提到,過去對偏頭痛的理解主要以血管和心理問題為主,現在的研究強調偏頭痛的生物學機制,展示出更全面的病因。此外,科學家們正尋找偏頭痛發作的觸發因素,從基本的神經系統到環境因素都可能影響病情。

    🎯 Key Points:
    - Gepants 是新一代偏頭痛藥物,已在英國獲準使用。
    - 偏頭痛的症狀多樣,且並不僅限於痛苦的頭痛,而是包括腦霧、感光和疲勞等。
    - 新研究顯示,偏頭痛的產生與大腦活動的改變及特定生物標記有關。
    - 需要更全面的研究來瞭解偏頭痛的觸發機制,以制定有效治療策略。
    - 預防和管理偏頭痛的藥物,如 CGRP 抑制劑,對某些患者效果顯著,但仍然存在適應性與普及性的挑戰。

    🔖 Keywords: #偏頭痛 #Gepants #CGRP #生物學機制 #新藥研究

  2. research article (2019):
    Puerarin suppresses TRPV1, calcitonin gene-related peptide and substance P to prevent paclitaxel-induced peripheral neuropathic pain in rats
    doi.org/10.1177/03331024177485
    ~
    Puerarin is a natural product found in kudzu root. Kudzu root is used to make Japanese kuzu noodles - don't know how much puerarin is in kuzu starch, but it's used traditionally as a digestive aid.

    #2badItsPaywalled #CGRP #TRPV1 #NaturalProducts #FunctionalFoods
    #puerarin #kuzu #neuropathy #ChronicPain

  3. research article (2019):
    Puerarin suppresses TRPV1, calcitonin gene-related peptide and substance P to prevent paclitaxel-induced peripheral neuropathic pain in rats
    doi.org/10.1177/03331024177485
    ~
    Puerarin is a natural product found in kudzu root. Kudzu root is used to make Japanese kuzu noodles - don't know how much puerarin is in kuzu starch, but it's used traditionally as a digestive aid.

    #2badItsPaywalled #CGRP #TRPV1 #NaturalProducts #FunctionalFoods
    #puerarin #kuzu #neuropathy #ChronicPain

  4. research article (2019):
    Puerarin suppresses TRPV1, calcitonin gene-related peptide and substance P to prevent paclitaxel-induced peripheral neuropathic pain in rats
    doi.org/10.1177/03331024177485
    ~
    Puerarin is a natural product found in kudzu root. Kudzu root is used to make Japanese kuzu noodles - don't know how much puerarin is in kuzu starch, but it's used traditionally as a digestive aid.

    #2badItsPaywalled #CGRP #TRPV1 #NaturalProducts #FunctionalFoods
    #puerarin #kuzu #neuropathy #ChronicPain