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  1. Huntington's disease treated for first time

    """
    It means the decline you would normally expect in one year would take four years after treatment, [..].

    The first symptoms of Huntington's disease tend to appear in your 30s or 40s and is normally fatal within two decades.
    """

    Wow, one might then very well merely die "with" it, instead of "from" it.

    bbc.com/news/articles/cevz13xk

    via @kottke

    #medicine #healthcare #HuntingtonsDisease #Huntingtons #kottke

  2. Huntington's disease treated for first time

    """
    It means the decline you would normally expect in one year would take four years after treatment, [..].

    The first symptoms of Huntington's disease tend to appear in your 30s or 40s and is normally fatal within two decades.
    """

    Wow, one might then very well merely die "with" it, instead of "from" it.

    bbc.com/news/articles/cevz13xk

    via @kottke

    #medicine #healthcare #HuntingtonsDisease #Huntingtons #kottke

  3. @caravantraveller @brooke

    This "deprecation" was never visible at any level, there's no discovery path for anyone that found or otherwise used these and stuck with it.

    But none of that matters: The most recent Debian 12 installer still unavoidably selects US/Pacific for people living there, today.

    rachelbythebay.com/w/2025/09/1

    Lobsters: lobste.rs/s/okz9ir/debian_12_i

  4. @caravantraveller @brooke

    This "deprecation" was never visible at any level, there's no discovery path for anyone that found or otherwise used these and stuck with it.

    But none of that matters: The most recent Debian 12 installer still unavoidably selects US/Pacific for people living there, today.

    rachelbythebay.com/w/2025/09/1

    Lobsters: lobste.rs/s/okz9ir/debian_12_i

    #tzdata #timezones #datetime #Postgres #PostgreSQL #RachelByTheBay

  5. @caravantraveller @brooke

    This "deprecation" was never visible at any level, there's no discovery path for anyone that found or otherwise used these and stuck with it.

    But none of that matters: The most recent Debian 12 installer still unavoidably selects US/Pacific for people living there, today.

    rachelbythebay.com/w/2025/09/1

    Lobsters: lobste.rs/s/okz9ir/debian_12_i

    #tzdata #timezones #datetime #Postgres #PostgreSQL #RachelByTheBay

  6. @caravantraveller @brooke

    This "deprecation" was never visible at any level, there's no discovery path for anyone that found or otherwise used these and stuck with it.

    But none of that matters: The most recent Debian 12 installer still unavoidably selects US/Pacific for people living there, today.

    rachelbythebay.com/w/2025/09/1

    Lobsters: lobste.rs/s/okz9ir/debian_12_i

    #tzdata #timezones #datetime #Postgres #PostgreSQL #RachelByTheBay

  7. @caravantraveller @brooke

    This "deprecation" was never visible at any level, there's no discovery path for anyone that found or otherwise used these and stuck with it.

    But none of that matters: The most recent Debian 12 installer still unavoidably selects US/Pacific for people living there, today.

    rachelbythebay.com/w/2025/09/1

    Lobsters: lobste.rs/s/okz9ir/debian_12_i

    #tzdata #timezones #datetime #Postgres #PostgreSQL #RachelByTheBay

  8. If you're running Debian 12 and Postgres, you're in or around the Americas, and you're planning on upgrading to Debian 13, you might hit a fun little snag [..]

    rachelbythebay.com/w/2025/09/1

  9. If you're running Debian 12 and Postgres, you're in or around the Americas, and you're planning on upgrading to Debian 13, you might hit a fun little snag [..]

    rachelbythebay.com/w/2025/09/1

    #tzdata #timezones #datetime #Postgres #PostgreSQL #RachelByTheBay

  10. If you're running Debian 12 and Postgres, you're in or around the Americas, and you're planning on upgrading to Debian 13, you might hit a fun little snag [..]

    rachelbythebay.com/w/2025/09/1

    #tzdata #timezones #datetime #Postgres #PostgreSQL #RachelByTheBay

  11. If you're running Debian 12 and Postgres, you're in or around the Americas, and you're planning on upgrading to Debian 13, you might hit a fun little snag [..]

    rachelbythebay.com/w/2025/09/1

    #tzdata #timezones #datetime #Postgres #PostgreSQL #RachelByTheBay

  12. If you're running Debian 12 and Postgres, you're in or around the Americas, and you're planning on upgrading to Debian 13, you might hit a fun little snag [..]

    rachelbythebay.com/w/2025/09/1

    #tzdata #timezones #datetime #Postgres #PostgreSQL #RachelByTheBay

  13. (Inspired by the BBC Tech report from @tdp_org)

    Yesterday, Wikipedia received over 45 million requests made with curl, from 113 distinct curl releases.

    Of these, 32 million use the default UA (e.g. curl CLI). The other 13 million embed libcurl with a longer UA string containing curl (e.g. GuzzleHttp/PHP, PycURL, UnityPlayer)

    At 12 million, most are curl/7.88.1.

    Raw data, queries, and scrub/cleaning parameters:
    gitlab.wikimedia.org/-/snippet

  14. False modesty a tautology?

    """
    Sally is a skilled musician but does not [know] she is exceptional. She may talk endlessly about her skills [which] may make others feel bad about their lesser ability. If she realized this, she can avoid [that] in the interest of modesty.

    [So,] we think a modest person thinks less of themself [but], McMullin argues, paradoxically, to be modest, you must [first] realize you surpass others, [to] then act [modest].
    """

    psychologytoday.com/us/blog/ma

  15. FOSDEM talk notes:

    dav1d 1.0. 200k LOC handwritten assembly. Don't know any other open or closed project that large. Faster than any compiler. Used by Android, Apple, Windows, Firefox, Chrome. Really really fast.

    fosdem.org/2023/schedule/event

    #fosdem #ffmpeg #dav1d #vlc

  16. FOSDEM talk notes:

    dav1d 1.0. 200k LOC handwritten assembly. Don't know any other open or closed project that large. Faster than any compiler. Used by Android, Apple, Windows, Firefox, Chrome. Really really fast.

    fosdem.org/2023/schedule/event

  17. FOSDEM talk notes:

    dav1d 1.0. 200k LOC handwritten assembly. Don't know any other open or closed project that large. Faster than any compiler. Used by Android, Apple, Windows, Firefox, Chrome. Really really fast.

    fosdem.org/2023/schedule/event

    #fosdem #ffmpeg #dav1d #vlc

  18. FOSDEM talk notes:

    dav1d 1.0. 200k LOC handwritten assembly. Don't know any other open or closed project that large. Faster than any compiler. Used by Android, Apple, Windows, Firefox, Chrome. Really really fast.

    fosdem.org/2023/schedule/event

    #fosdem #ffmpeg #dav1d #vlc

  19. FOSDEM talk notes:

    dav1d 1.0. 200k LOC handwritten assembly. Don't know any other open or closed project that large. Faster than any compiler. Used by Android, Apple, Windows, Firefox, Chrome. Really really fast.

    fosdem.org/2023/schedule/event

    #fosdem #ffmpeg #dav1d #vlc

  20. How does Wikimedia approach security and performance?

    We're quite selective in our dependencies and often audit the sources ourselves. Progressive enhancement makes for a blazing fast and accessible site, and, I argue, it's also the cheaper choice in the long run!

    timotijhof.net/posts/2023/wiki

  21. Chromium on Android: How we gained a 2x speed up on Speedometer benchmark
    by Eric Seckler.

    Will dive into build optimizations and their impact on CPU bottlenecks, discuss the relevance of benchmarking end-to-end user journeys, and how they built a novel page load benchmark to allow optimizing across the software/hardware stack.

    fosdem.org/2025/schedule/event

    Live stream:
    live.fosdem.org/watch/ua2220