#teamclots — Public Fediverse posts

From the US

Blood pro-thrombotic analytes and platelet activation are associated with post-acute sequelae of COVID-19

https://link.springer.com/article/10.1186/s12879-025-11824-3

Screenshot from Science for ME weekly update

#TeamClots @longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

Circulating Microclots Are Structurally Associated With Neutrophil Extracellular Traps and Their Amounts Are Elevated in Long COVID Patients

https://onlinelibrary.wiley.com/doi/10.1002/jmv.70613

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #CovidIsNotOver
#auscovid19
#TeamClots #PASC

Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestry

https://www.medrxiv.org/content/10.1101/2024.05.17.24307553v3?ct=

"our findings indicate that thromboembolic pathways may contribute to #longCOVID independently of acute disease severity"

#TeamClots @longcovid
#PwLC #PostCovidSyndrome #LC #PASC #postcovid #CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #SARSCoV2 @[email protected] #novid @[email protected] #CovidIsNotOver #auscovid19

2/

"in the rat models, the concentration of microthrombus is reduced by more than 60% in 3 minutes"

Hashtags:
@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @[email protected] #novid @[email protected] #CovidIsNotOver #auscovid19 @auscovid19 #TeamClots

Interventional Removal of Travelling Microthrombi Using Targeted Magnetic Microbubble

https://onlinelibrary.wiley.com/doi/10.1002/adhm.202401631

"In this work, an interventional method is developed to identify & remove the traveling microthrombi using targeted-magnetic microbubbles (TMMBs) & an interventional magnetic catheter”

@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 #TeamClots
1/

2/

"Our study revealed that NETs may be a component of circulating FAM, suggesting that higher NETs formation promotes the stabilization of FAM in the circulation, leading to deleterious effects which (in part) may contribute to the symptoms of LC."

Hashtags:
@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
#LongCovid #TeamClots

New pre-print:
Circulating microclots are structurally associated with Neutrophil Extracellular Traps and their amounts are strongly elevated in long COVID patients

https://www.researchsquare.com/article/rs-4666650/v1

====
Hashtags:
@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid #CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @[email protected] #novid @[email protected] #CovidIsNotOver #auscovid19 @auscovid19
#TeamClots

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3/
New pre-print:

Flow Clotometry: Measuring Amyloid Microclots in ME/CFS, Long COVID, and Healthy Samples with Imaging Flow Cytometry

https://www.researchsquare.com/article/rs-4507472/v1

Hashtags:
@longcovid
#LongCovid #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #PASC #COVIDBrain
#TeamClots @mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @covid19

2/
Microclot concentrations determined by the present cell-free flow clotometry technique for the three cohorts

from

Flow Clotometry: Measuring Amyloid Microclots in #MECFS, #LongCOVID, & Healthy Samples with Imaging Flow Cytometry

https://www.researchsquare.com/article/rs-4507472/v1
#TeamClots #CFS #PwME @longcovid @mecfs @covid19

🧵
New pre-print:

Flow Clotometry: Measuring Amyloid Microclots in ME/CFS, Long COVID, and Healthy Samples with Imaging Flow Cytometry

https://www.researchsquare.com/article/rs-4507472/v1

=========
@longcovid
#LongCovid #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #PASC #COVIDBrain
#TeamClots #MEcfs #CFS #PwME @mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2

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A detailed article giving varying perspectives of scientists on the validity of the hypotheses, and the need for clinical trials of treatments currently being sold to patients.

Hashtags:

@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #auscovid19 @auscovid19

#CovidLong #PostCovid19 #TeamClots

Increased fibrinaloid microclot counts in platelet-poor plasma are associated with #LongCOVID

https://t.ly/7bSYH

Replication study of microclots by a UK team using an automated quantification method and refining sampling handling to reduce the potential for processing artifacts

#TeamClots @longcovid
#PwLC #PostCovidSyndrome #LC #PASC #postcovid
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #CovidBrain @auscovid19

Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID

Free full text:
https://www.mdpi.com/2075-4426/14/2/170

#teamclots @longcovid
#LongCovid #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #PASC

@covid19 #Coronavirus
#COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #COVIDBrain
@auscovid19

Newly announced upcoming clinical trial:

"A clinical trial to test if the fibrinolytic enzyme Lumbrokinase improves symptoms and mitigates blood clotting issues or platelet hyperactivation in patients with #LongCOVID, ME/CFS, & LongLyme disease."

https://polybio.org/projects/lumbrokinase-longcovid-me-cfs-clinical-trial/

@mecfs

#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME #TeamClots @longcovid
#PwLC #postcovid #postcovid19 #LC #PostCovidSyndrome #longhaulers #PASC
@covid19 #Coronavirus
#COVID19 #COVID #SARSCoV2

Good news! My microclots are no longer severe! I’m in the safe zone after 8 months of TT then DT 🎉

Thanks much to #TeamClots for confirming suspicions many of us had + my Long Covid microclot doctor for the assist! Hope it stays this way as long as possible

June 2023 versus February 2024
#MECFS #LongCovid

3D Holo-Tomographic Mapping Of #Covid19 Microclots In Blood To Assess Disease Severity

https://pubs.acs.org/doi/10.1021/cbmi.3c00126

“the label-free DHTM-based approach demonstrated in our study could serve as a powerful tool for screening microclots in plasma.”

#TeamClots @covid19
#COVIDー19 #COVID19 #COVID_19 #SARSCoV2 #novid #CovidIsNotOver #CovidBrain
Not a #LongCovid study but the tool may be useful to investigate it.

#PwLC #PostCovidSyndrome #LC #PASC #postcovid

3/

“We will offer a £25 Love2Shop voucher for each participant who provides a blood sample”

#MEcfs #MyalgicE #CFS #PwME #MyalgicEncephalomyelitis #ChronicFatigueSyndrome #TeamClots
@mecfs #sheffield #sheffieldfolk

2/

People interested in this research might be interested in this talk, "Vascular pathology in post-viral conditions: the role of #Microclots" by Dr Nolan &
@resiapretorius from last December

https://www.youtube.com/watch?v=uDbwNFBz7Y8

#TeamClots #MEcfs #CFS #PwME #LongCovid #PwLC #postcovid @mecfs

Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to #SARSCoV2 Infection

https://t.ly/r3ycf

“We have also demonstrate the fine balance between coagulation & fibrinolysis could be readily impaired & identified a possible role of Annexin A2 in coagulopathy developed after #SARSCoV2 infection”

@longcovid
#LongCovid #PwLC #LC #PASC #postcovid @covid19
#COVIDー19 #COVID19 #COVID #TeamClots

Fibrin microthrombi in bladder urothelium after #SARSCoV2 infection: Case report

https://shorturl.at/cmDN5

“this study suggest[s] increased levels of IL-8 in the bladder may drive microthrombi in the bladder vasculature & urinary IL-8 levels might provide a means of detecting if a patient is at risk for developing symptoms from these microthrombi after SARS-CoV-2 infection”

#TeamClots #MicroClots @longcovid
#LongCovid #PwLC #LC #PASC #postcovid
#COVIDー19 #COVID19 #COVID

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“Our findings highlight that label-free high-throughput microscopy can be used as a point-of-care technique to visualize and quantify the presence of microclots directly in plasma without the need for complicated sample preparation techniques.”

#microclots #TeamClots

Digital holo-tomographic 3D maps of #COVID19 #microclots in blood to assess disease severity

Free:
https://tinyurl.com/4kkrs76s

“fewer microclots and platelet aggregates were detected in the plasma of healthy controls when compared to #COVID-19 donors”

#teamclots @longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #postcovid @covid19
#COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2

1/

>>Individuals with elevated D-dimer levels were not only more prone to brain fog but also displayed a heightened risk of respiratory challenges<<

#LongCovid #SarsCoV2 #Covid #TeamClots

https://www.theguardian.com/society/2023/aug/31/uk-scientists-find-link-between-proteins-related-to-blood-clots-and-long-covid?CMP=Share_AndroidApp_Other

@AshleyMarineP The clinics are mentioned later in the thread!

I know the Sheffield clinic knows microclots but it’s focused on research only and not public treatment

If you search through the main #TeamClots researchers and doctors on Twitter (they haven’t migrated much here yet), there may be more tweets about other UK folks they’ve trained on microclots closer to you

I’ll keep updating as TT goes on

Waiting for labs to show further risk factors #TeamClots

Having these improvements that I honestly began to think were impossible just 2 weeks into TT has me thinking everyone with #MECFS #POTS #LongCovid should test for and treat microclots 10/

#MECFS and #LongCovid microclot treatment developments, a thread I’ll keep updating:

A month ago I started my first med of TT (triple anticoagulant therapy); it’s been 2 weeks since I’ve been on all 3 meds

Already I’m noticed significant improvements in decades-long issues #TeamClots 1/?

This test should be widespread, every doctor off or on #MedTwitter should know about it

Not enough patients know about #TeamClots or have money for tests (I’ll have to do a fundraiser to afford treatment)

This is serious, it impacts so much; keep looking #MECFS #LongCovid #pwME

I’ve been on Xarelto after a PE for 1.5 years, but felt very inflamed for 2 years

I said “I think I have microclots” then “is my daily anticoagulant enough?”

I was right: I have microclots and Xarelto wasn’t enough

Don’t give up on answers

#pwME #LongCovid #MECFS #TeamClots

New publication of so-called #TeamClots with #ResiaPretorius on the pathophysiology of #LongCovid. The focus is on #Microclots.
But also other theories like #Autoimmunity and #ViralPersistence are mentioned.

#PostCovid #MECFS #Covid #Corona #Covid19 #Science

https://www.sciencedirect.com/science/article/pii/S1043276023000553

Update on #TripleTherapy for #LongCovid #PwLC #MECFS #PwME #TeamClots

Almost 23 months into LC. Main symptoms: fatigue, headaches, tinnitus, brain fog, especially after cognitive activity. Just started week 7 of aspirin, apixaban, clopidogrel + also taking atorvastatin.

Some small improvements:
* clearer thinking, focus
* on some days, increased SpO2 from generally 95 to 97-99
* haven’t woken up with extremely numb hands during the night

1/2

@DysautonomiaZA - I know a bunch of #mecfs and #longcovid patients who got their testing done in Germany. #TeamClots found that all #pwLC and pwME had these #Fibrin and #Fibrinogen #microclots.

Many of us have been taking #NattoSerra blend enzymes that help reduce microclots.
It has really helped me. MCAS patients, it has hitamine so lumbrokinase might be a better option.

NIH has published studies about these enzymes if anyone is interested.

There's not much to love about #LongCovid but I'd love to have it go away. My #Christmas homage to the movie #loveactually #pwLC #teamclots #CovidIsNotOver #fblc @longcovidsos

The story of how our researchers at Stellenbosch University found #microclots in the plasma of #pwLC.
#LongCovid affects an estimated 1.2 million South Africans.
#SouthAfrica
#TeamClots
#COVID19

https://bit.ly/3v86lhV

My latest #longcovid #blog post. That term we all hate-- Brain Fog. My hot take on the cognitive issues related to Long Covid including my very personal experiences. http://www.seekingbostonmarathon.com/2022/11/long-covid-brain-fog-is-not-fog-its.html?m=1 #pwLC #fblc #NotRecovered #teamclots

Thinking #nattokinase may be working. I worked yesterday and am not totally spent today. #LongCovid #teamclots

@LongCovidKris Im still on twitter. This seems very disconnected. Hope we don't have to migrate because we will be leaving so many behind 😢
#inthistogether
#pwLC
#pwME
#teamclots
#NoOneGetsLeftBehind