#microclots — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #microclots, aggregated by home.social.
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🎉Breaking news: Scientists discover kids with Long Covid have #microclots (who knew blood clots could be fun-sized?!) 🤡. This "study" is so fresh, it hasn't even been peer-reviewed—because who needs verification when you have microfluidic assays to throw around like confetti? 🎈🔬
https://www.researchsquare.com/article/rs-7483367/v1 #BreakingNews #LongCovid #ScienceFun #ResearchTrends #HackerNews #ngated -
Blood test detecting Long Covid in kids with 94% accuracy microclots
https://www.researchsquare.com/article/rs-7483367/v1
#HackerNews #BloodTest #LongCovid #Kids #Microclots #HealthTech
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By @RTHM_Health
"A new study suggests that exercise doesn’t clear microclots in people with Long COVID—it just fragments them into smaller ones. These smaller clots are linked to increased inflammation and impaired oxygen transport, which may help explain post-exertional malaise (PEM) and post-exertional symptom exacerbation (PESE)—a worsening of symptoms after even mild physical or mental effort."
"Researchers observed these microclot and inflammatory changes even after submaximal exertion, highlighting the need for caution when recommending exercise-based therapies."
Want more research breakdowns like this? Sign up for our email list at https://linktr.ee/rthm_health
🔗 DOI: https://doi.org/10.21203/rs.3.rs-6717727/v1
#LongCOVID #ChronicFatigue #pwLC #PostCOVID #rthm_health #LongCOVIDResearch #PESE #PEM #IACC #COVID19 #Microclots @auscovid19
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By @RTHM_Health
"A new study suggests that exercise doesn’t clear microclots in people with Long COVID—it just fragments them into smaller ones. These smaller clots are linked to increased inflammation and impaired oxygen transport, which may help explain post-exertional malaise (PEM) and post-exertional symptom exacerbation (PESE)—a worsening of symptoms after even mild physical or mental effort."
"Researchers observed these microclot and inflammatory changes even after submaximal exertion, highlighting the need for caution when recommending exercise-based therapies."
Want more research breakdowns like this? Sign up for our email list at https://linktr.ee/rthm_health
🔗 DOI: https://doi.org/10.21203/rs.3.rs-6717727/v1
#LongCOVID #ChronicFatigue #pwLC #PostCOVID #rthm_health #LongCOVIDResearch #PESE #PEM #IACC #COVID19 #Microclots @auscovid19
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By @RTHM_Health
"A new study suggests that exercise doesn’t clear microclots in people with Long COVID—it just fragments them into smaller ones. These smaller clots are linked to increased inflammation and impaired oxygen transport, which may help explain post-exertional malaise (PEM) and post-exertional symptom exacerbation (PESE)—a worsening of symptoms after even mild physical or mental effort."
"Researchers observed these microclot and inflammatory changes even after submaximal exertion, highlighting the need for caution when recommending exercise-based therapies."
Want more research breakdowns like this? Sign up for our email list at https://linktr.ee/rthm_health
🔗 DOI: https://doi.org/10.21203/rs.3.rs-6717727/v1
#LongCOVID #ChronicFatigue #pwLC #PostCOVID #rthm_health #LongCOVIDResearch #PESE #PEM #IACC #COVID19 #Microclots @auscovid19
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By @RTHM_Health
"A new study suggests that exercise doesn’t clear microclots in people with Long COVID—it just fragments them into smaller ones. These smaller clots are linked to increased inflammation and impaired oxygen transport, which may help explain post-exertional malaise (PEM) and post-exertional symptom exacerbation (PESE)—a worsening of symptoms after even mild physical or mental effort."
"Researchers observed these microclot and inflammatory changes even after submaximal exertion, highlighting the need for caution when recommending exercise-based therapies."
Want more research breakdowns like this? Sign up for our email list at https://linktr.ee/rthm_health
🔗 DOI: https://doi.org/10.21203/rs.3.rs-6717727/v1
#LongCOVID #ChronicFatigue #pwLC #PostCOVID #rthm_health #LongCOVIDResearch #PESE #PEM #IACC #COVID19 #Microclots @auscovid19
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#SARSCoV2 persistence in platelet-producing lung cells:
"Accordingly, in all samples analyzed, circulating MK [megakaryocyte] in Long COVID sheltered both Spike and SARS-CoV-2 ssRNA [single-stranded RNA], but also dsRNA [double-stranded RNA] suggestive of viral replication. [...] Platelets microclots were detected in all tested Long COVID patients."
#covid #covid19 #LongCovid #pandemic #MicroClots #PublicHealth #CovidIsNotOver
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>>We conclude that the presence of fibrinaloid #microclots can indeed significantly account for the symptoms of #POTS associated with #LongCovid (and likely other syndromes), just as they can for other symptoms, post-exertional symptom exacerbation, and the generation of autoantibodies<<
Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10890060/ -
New research on severe #microclots and #POTS!
“We here develop the argument, with accompanying evidence, that fibrinaloid microclots, through their ability to block the flow of blood through microcapillaries and thus cause tissue hypoxia, are not simply correlated with but in fact, by preceding it, may be a chief intermediary cause of POTS, in which tachycardia is simply the body’s exaggerated ‘physiological’ response to hypoxia.”
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We're learning more and more about long covid.
Plummeting levels of certain hormones may explain the fatigue and brain fog. "Microclots" in the blood may play a role. And the virus's ability to persist in our bodies may be crucial.
#LongCovid #microclots #ViralReservoir
https://www.newscientist.com/article/mg26034670-800-long-covid-what-we-now-know-about-its-causes-and-possible-treatments/
#science #scientist -
We're learning ever more about #LongCovid.
Plummeting levels of certain hormones may explain the fatigue and brain fog. " #microclots" in the blood may play a role. And the virus's ability to persist in our bodies may be crucial.
https://www.newscientist.com/article/mg26034670-800-long-covid-what-we-now-know-about-its-causes-and-possible-treatments/
#science #scientist -
Almost four years after the first cases of long covid emerged, we are accumulating evidence about the physiology behind this complex condition – from microclots to viral persistence
#LongCovid #microclots #ViralReservoir
https://www.newscientist.com/article/mg26034670-800-long-covid-what-we-now-know-about-its-causes-and-possible-treatments/
#science #scientist -
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People interested in this research might be interested in this talk, "Vascular pathology in post-viral conditions: the role of #Microclots" by Dr Nolan &
@resiapretorius from last Decemberhttps://www.youtube.com/watch?v=uDbwNFBz7Y8
#TeamClots #MEcfs #CFS #PwME #LongCovid #PwLC #postcovid @mecfs
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Fibrin microthrombi in bladder urothelium after #SARSCoV2 infection: Case report
“this study suggest[s] increased levels of IL-8 in the bladder may drive microthrombi in the bladder vasculature & urinary IL-8 levels might provide a means of detecting if a patient is at risk for developing symptoms from these microthrombi after SARS-CoV-2 infection”
#TeamClots #MicroClots @longcovid
#LongCovid #PwLC #LC #PASC #postcovid
#COVIDー19 #COVID19 #COVID -
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“Our findings highlight that label-free high-throughput microscopy can be used as a point-of-care technique to visualize and quantify the presence of microclots directly in plasma without the need for complicated sample preparation techniques.”
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Digital holo-tomographic 3D maps of #COVID19 #microclots in blood to assess disease severity
Free:
https://tinyurl.com/4kkrs76s“fewer microclots and platelet aggregates were detected in the plasma of healthy controls when compared to #COVID-19 donors”
#teamclots @longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #postcovid @covid19
#COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV21/
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"NPR interviewed scientists who are looking at microclots found in the blood of people with #LongCOVID. These #microclots are unusual in that they are made up mostly of an abnormal type of fibrin and form unusual shapes called amyloid. These fibrin amyloid microclots may be a biomarker for long COVID. Another group had an article on microclots and long COVID. They suggest the term “spike protein induced thrombotic vasculitis” (SITV) to describe the pathophysiology of long #COVID #clotting."
https://drruth.substack.com/p/covid-news-and-more-52023
3/n
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#Texas folks—
Celestia Diagnostics in #Dallas is looking for volunteers for their #microclots research. Cool opportunity as it’s one of the most promising avenues in #LongCovid research, but currently really hard to access testing for (one of the things they’re hoping to fix).
If you’re up for a blood draw either as healthy control (thank you 🙌🏻) or as someone w/LC #MECFS #RheumatoidArthritis or #Diabetes (thank you also 💛), you can sign up here:
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New publication of so-called #TeamClots with #ResiaPretorius on the pathophysiology of #LongCovid. The focus is on #Microclots.
But also other theories like #Autoimmunity and #ViralPersistence are mentioned.#PostCovid #MECFS #Covid #Corona #Covid19 #Science
https://www.sciencedirect.com/science/article/pii/S1043276023000553
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A social and medical examination of Long COVID as a “mass disabling event”: Part 2 - World Socialist Web Site
#Covid
#MassDisablingEvent
#LongCOVID
#PersistantVirus
#MicroClots
#ImmuneSystems
#GutBacteria
#GutBiome
https://www.wsws.org/en/articles/2023/04/05/long-a05.html -
A social and medical examination of Long COVID as a “mass disabling event”: Part 2 - World Socialist Web Site
#Covid
#MassDisablingEvent
#LongCOVID
#PersistantVirus
#MicroClots
#ImmuneSystems
#GutBacteria
#GutBiome
https://www.wsws.org/en/articles/2023/04/05/long-a05.html -
A social and medical examination of Long COVID as a “mass disabling event”: Part 2 - World Socialist Web Site
#Covid
#MassDisablingEvent
#LongCOVID
#PersistantVirus
#MicroClots
#ImmuneSystems
#GutBacteria
#GutBiome
https://www.wsws.org/en/articles/2023/04/05/long-a05.html -
A social and medical examination of Long COVID as a “mass disabling event”: Part 2 - World Socialist Web Site
#Covid
#MassDisablingEvent
#LongCOVID
#PersistantVirus
#MicroClots
#ImmuneSystems
#GutBacteria
#GutBiome
https://www.wsws.org/en/articles/2023/04/05/long-a05.html -
A social and medical examination of Long COVID as a “mass disabling event”: Part 2 - World Socialist Web Site
#Covid
#MassDisablingEvent
#LongCOVID
#PersistantVirus
#MicroClots
#ImmuneSystems
#GutBacteria
#GutBiome
https://www.wsws.org/en/articles/2023/04/05/long-a05.html -
Yes, this is an important question. I suspect that the #microclots play only a minor role.
This study was the first to demonstrate substantial problems in membrane transport of sodium in #MECFS patients:
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There are four categories for #MECFS. The ones who’ve had it the longest with multiple immune events (including but not limited to infections) are the ones who get/stay worse.
MEAction says 95 percent never recover from MECFS.
I hovered between mild and moderate for decades. Immune events and #MitoDisease (seen in #LongCovid too) kicked me between moderate and severe for the last 4-5 years.
Supplements and meds keep me from being very severe. I’m sure MECFS #microclots made it worse too.
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@DysautonomiaZA - I know a bunch of #mecfs and #longcovid patients who got their testing done in Germany. #TeamClots found that all #pwLC and pwME had these #Fibrin and #Fibrinogen #microclots.
Many of us have been taking #NattoSerra blend enzymes that help reduce microclots.
It has really helped me. MCAS patients, it has hitamine so lumbrokinase might be a better option.NIH has published studies about these enzymes if anyone is interested.
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@lqlqlq yes, many #mecfs and #LongCovid patients have tried it. I am taking it too. If you have #MCAS have to be more careful. #NattoSerra combination works well for fibrin #microclots.
This might help:
https://pharmd.substack.com/p/frequency-asked-questions-nattokinase -
The story of how our researchers at Stellenbosch University found #microclots in the plasma of #pwLC.
#LongCovid affects an estimated 1.2 million South Africans.
#SouthAfrica
#TeamClots
#COVID19
