#nanobodies — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #nanobodies, aggregated by home.social.
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https://www.europesays.com/at/154304/ Nanobodies zur Prävention der Bienenstich Anaphylaxie #Anaphylaxie #ApiM1 #AT #Austria #Bienenstichallergie #Gesundheit #Health #IgE #Nanobodies #Österreich
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#Methode
Fluoreszenz-Marathonläufer vs. Sprinter: Forschende der @unigoettingen
nutzen #FluoreszenzlebensdauerMikroskopie & HaloTag-Nanobodies, um Zielproteine zu detektieren und trotz spektraler Überlappung exakt auseinander zu halten.Mehr im Artikel von Andrea Pitzschke: https://www.laborjournal.de/editorials/3450.php
#Laborjournal #LifeSci #FLIM #Nanobodies #HaloTag #Mikroskopie #Zellbiologie #MultiplexImaging #Immunofluorescence
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#Pflanzen mit einem adaptiven #Immunsystem ausstatten – nur eine schöne Vision? Mit #Nanobodies und genetischen Eingriffen ist man diesem Ziel nun einen Schritt näher gekommen. Karin Hollricher erklärt auch, was dies für #Pflanzenschutz und -anbau bedeuten könnte: https://www.laborjournal.de/editorials/3357.php
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How do diverse synapses in the brain organize their nanoarchitecture? This study uses #nanobodies & STED imaging to study the nanoarchitecture of thalamocortical & corticocortical #synapses, revealing distinct principles of synaptic nano-organization in the brain @PLOSBiology https://plos.io/3FY4vcd
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#Structure defining of ultrapotent neutralizing #nanobodies against #MERS-CoV with novel epitopes on #receptor binding domain https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012438
These results not only character unprecedented epitopes for antibody recognition but also provide promising agents for prophylaxis and therapy of MERS-CoV infection.
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17-JUL-2024
#Llama #nanobodies: A breakthrough in building HIV immunity
Biology researchers at Georgia State have developed a new antibody therapy that can neutralize a wide variety of #HIV-1 strains. They found success in an unlikely source — llamas.It's 24 years since I wrote my first articles about camel and llama #antibodies, so the PR people could tone down the "unlikely" a little bit.
https://www.eurekalert.org/news-releases/1051719 #science #nanoworld
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Could the blood of camel species help save us from serious diseases? | DW Documentary
What’s known as #nanobodies from the blood of #camels are at the heart of a #medical revolution. Due to their special properties, these nanobodies can be used in a variety of ways, whether in the fight against #infectious diseases, in #cancer therapy or in the diagnosis of #Alzheimer's disease.
Small #antibodies with a big impact: camel blood contains #immunological superpowers. It all began in the 1990s with a chance #discovery at the Free #University of #Brussels: students used #dromedary blood in an experiment and came across previously unknown antibodies. The university #scientists discovered that these antibodies are present in all camel species. And, they have amazing properties. Small fragments can separate from the base of the antibody -- without causing any damage and while retaining their full binding capacity.
This was the discovery of the nanobody: a tiny, extremely robust #molecule which, due to its small size, can also penetrate areas too small to be targeted by complete antibodies. The nanobody, however, can attach itself with extremely high precision to pathogenic antigens.
This discovery triggered a wave of innovations and shook up the big #pharmaceutical companies. In 2018, the first drug based on nanobodies went on the market, designed to combat an autoimmune #blood clotting disorder. Numerous potential applications were developed within a very short space of time. Whether in the fight against cancer, in Alzheimer's diagnostics or to kill #pathogenic #bacteria - the success of camel antibodies has been so resounding that many #medical research centers now have their own herds of llamas or alpacas.
But why do members of the camel family in particular have such immunological superpowers? With the help of camel experts and microbiologists, the documentary sheds light on the surprising abilities of camels and the medical revolution of nanobodies.
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Could the blood of camel species help save us from serious diseases? | DW Documentary
What’s known as #nanobodies from the blood of #camels are at the heart of a #medical revolution. Due to their special properties, these nanobodies can be used in a variety of ways, whether in the fight against #infectious diseases, in #cancer therapy or in the diagnosis of #Alzheimer's disease.
Small #antibodies with a big impact: camel blood contains #immunological superpowers. It all began in the 1990s with a chance #discovery at the Free #University of #Brussels: students used #dromedary blood in an experiment and came across previously unknown antibodies. The university #scientists discovered that these antibodies are present in all camel species. And, they have amazing properties. Small fragments can separate from the base of the antibody -- without causing any damage and while retaining their full binding capacity.
This was the discovery of the nanobody: a tiny, extremely robust #molecule which, due to its small size, can also penetrate areas too small to be targeted by complete antibodies. The nanobody, however, can attach itself with extremely high precision to pathogenic antigens.
This discovery triggered a wave of innovations and shook up the big #pharmaceutical companies. In 2018, the first drug based on nanobodies went on the market, designed to combat an autoimmune #blood clotting disorder. Numerous potential applications were developed within a very short space of time. Whether in the fight against cancer, in Alzheimer's diagnostics or to kill #pathogenic #bacteria - the success of camel antibodies has been so resounding that many #medical research centers now have their own herds of llamas or alpacas.
But why do members of the camel family in particular have such immunological superpowers? With the help of camel experts and microbiologists, the documentary sheds light on the surprising abilities of camels and the medical revolution of nanobodies.
-
Could the blood of camel species help save us from serious diseases? | DW Documentary
What’s known as #nanobodies from the blood of #camels are at the heart of a #medical revolution. Due to their special properties, these nanobodies can be used in a variety of ways, whether in the fight against #infectious diseases, in #cancer therapy or in the diagnosis of #Alzheimer's disease.
Small #antibodies with a big impact: camel blood contains #immunological superpowers. It all began in the 1990s with a chance #discovery at the Free #University of #Brussels: students used #dromedary blood in an experiment and came across previously unknown antibodies. The university #scientists discovered that these antibodies are present in all camel species. And, they have amazing properties. Small fragments can separate from the base of the antibody -- without causing any damage and while retaining their full binding capacity.
This was the discovery of the nanobody: a tiny, extremely robust #molecule which, due to its small size, can also penetrate areas too small to be targeted by complete antibodies. The nanobody, however, can attach itself with extremely high precision to pathogenic antigens.
This discovery triggered a wave of innovations and shook up the big #pharmaceutical companies. In 2018, the first drug based on nanobodies went on the market, designed to combat an autoimmune #blood clotting disorder. Numerous potential applications were developed within a very short space of time. Whether in the fight against cancer, in Alzheimer's diagnostics or to kill #pathogenic #bacteria - the success of camel antibodies has been so resounding that many #medical research centers now have their own herds of llamas or alpacas.
But why do members of the camel family in particular have such immunological superpowers? With the help of camel experts and microbiologists, the documentary sheds light on the surprising abilities of camels and the medical revolution of nanobodies.
-
Could the blood of camel species help save us from serious diseases? | DW Documentary
What’s known as #nanobodies from the blood of #camels are at the heart of a #medical revolution. Due to their special properties, these nanobodies can be used in a variety of ways, whether in the fight against #infectious diseases, in #cancer therapy or in the diagnosis of #Alzheimer's disease.
Small #antibodies with a big impact: camel blood contains #immunological superpowers. It all began in the 1990s with a chance #discovery at the Free #University of #Brussels: students used #dromedary blood in an experiment and came across previously unknown antibodies. The university #scientists discovered that these antibodies are present in all camel species. And, they have amazing properties. Small fragments can separate from the base of the antibody -- without causing any damage and while retaining their full binding capacity.
This was the discovery of the nanobody: a tiny, extremely robust #molecule which, due to its small size, can also penetrate areas too small to be targeted by complete antibodies. The nanobody, however, can attach itself with extremely high precision to pathogenic antigens.
This discovery triggered a wave of innovations and shook up the big #pharmaceutical companies. In 2018, the first drug based on nanobodies went on the market, designed to combat an autoimmune #blood clotting disorder. Numerous potential applications were developed within a very short space of time. Whether in the fight against cancer, in Alzheimer's diagnostics or to kill #pathogenic #bacteria - the success of camel antibodies has been so resounding that many #medical research centers now have their own herds of llamas or alpacas.
But why do members of the camel family in particular have such immunological superpowers? With the help of camel experts and microbiologists, the documentary sheds light on the surprising abilities of camels and the medical revolution of nanobodies.
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In der Bibel ist es Ägyptens "fünfte Plage": Milzbrand. Eine Krankheit, die selten geworden, aber immer noch bedrohlich und potenziell tödlich ist. Winzige #Nanobodies, zufällig entdeckt in Kamelblut, können die Panzerung der Milzbrand-Bakterien durchbrechen.
Falls ihr unsere Wissenschaftsdoku noch nicht gesehen habt: Sie erzählt die verrückte Geschichte von der zufälligen Entdeckung der Nanobodies: https://www.3sat.de/wissen/wissenschaftsdoku/240606-sendung-winzige-antikoerper-boost-fuers-immunsystem-wido-100.html?at_medium=Social%20Media&at_campaign=Mastodon&at_specific=3sat -
Hoffnung für Schwerstkranke (#Alzheimer, #Krebs… ) durch #Nanobodies - winzige Antikörper von #Kamele.n, die sonst bei keinem anderen Säugetier zu finden sind?
Die Tiere sind auch selten krank. Was macht sie so widerstansfähig?
Gerade bei WissenHoch2 in @3sat
👇
https://www.3sat.de/wissen/wissenschaftsdoku/240606-sendung-winzige-antikoerper-boost-fuers-immunsystem-wido-100.html -
Kamele werden selten krank und liefern einen genialen Grundstoff für wirkungsvolle Medikamente: #Nanobodies - winzige Antikörper, die sonst bei keinem anderen Säugetier zu finden sind. Unsere #Wissenschaftsdoku erzählt die verrückte Geschichte von der zufälligen Entdeckung der Nanobodies und ihres kometenhaften Aufstiegs in der medizinischen Forschung.
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7-Dec-2023
Llama power: Tiny llama nanobodies neutralize different #noroviruses. Can they improve human anti-viral therapies?https://www.eurekalert.org/news-releases/1010480 #science #nanoworld #nanobodies #LlamaAntibodies
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Postdoc Positions in Structural biochemistry / Molecular + Cell Biology
Stanford University
Seeking creative structural or cell bio postdocs at #Stanford to work on #membrane proteins and #nanobodies
See the full job description on jobRxiv: https://jobrxiv.org/job/stanford-university-27778-postdoc-positions-in-structural-biochemistry-molecular-cell-biology/?...
https://jobrxiv.org/job/stanford-university-27778-postdoc-positions-in-structural-biochemistry-molecular-cell-biology/?feed_id=55247 -
Postdoc Positions in Structural biochemistry / Molecular + Cell Biology
Stanford University
Seeking creative structural or cell bio postdocs at #Stanford to work on #membrane proteins and #nanobodies
See the full job description on jobRxiv: https://jobrxiv.org/job/stanford-university-27778-postdoc-positions-in-structural-biochemistry-molecular-cell-biology/?...
https://jobrxiv.org/job/stanford-university-27778-postdoc-positions-in-structural-biochemistry-molecular-cell-biology/?feed_id=52419 -
Postdoc Positions in Structural biochemistry / Molecular + Cell Biology
Stanford University
Seeking creative structural or cell bio postdocs at #Stanford to work on #membrane proteins and #nanobodies
See the full job description on jobRxiv: https://jobrxiv.org/job/stanford-university-27778-postdoc-positions-in-structural-biochemistry-molecular-cell-biology/?...
https://jobrxiv.org/job/stanford-university-27778-postdoc-positions-in-structural-biochemistry-molecular-cell-biology/?feed_id=51083 -
The efficiency of #protein complexes isolation from complex cell extracts is usually very low. Novel tags and biotinylated #nanobodies could help improve the yields. Impressive work (pre-print in #biorxiv)
https://www.biorxiv.org/content/10.1101/2023.03.09.531980v1.full
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PhD position available in our group in Marseille. If you are interesting in working on a collaborative project under the umbrella of the Turing Centre of Living Systems and are excited about #imaging #muscle #drosophila #nanobodies apply to us.
https://centuri-livingsystems.org/phd2023-04/ -
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Unsere Zahl des Monats im Dezember ist...6
...Alpakas haben wir auf Riems.🦙
Aus dem Blut von #Alpakas kann man an die Baupläne für #Nanobodies gelangen. Es gibt vielfältige Anwendungsmöglichkeiten für Nanobodies, beispielsweise in der Zoonosenforschung wie #SARSCoV2- oder #Toxoplasmose. @RKI
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Die #COVID-19-Pandemie und das Auftreten neuer Varianten erfordern die #Entwicklung verbesserter #Therapeutika. Unsere #Nanobodies haben großes #Potential auch zukünftige Pandemien schnell in den Griff zu bekommen - @[email protected] , @[email protected], @[email protected] -
https://bit.ly/3qcbjY1 -
Alpakas gegen Coronaviren
Im Blut eines Alpakas-Männchens und eines Lamas haben Forschende Antikörperfragmente gegen das Coronavirus entdeckt. "Nanobodies" nennen Wissenschaftler diese Wirkstoffklasse.
#3SatNano #Corona #Covid #SarsCoV #nanobodies
Video 4 min
https://www.3sat.de/wissen/nano/210615-lamas--nano-100.html -
Hurrah! After a whole week rattling around the back of a UPS van (and many frustrating phone calls), my bacteria have finally arrived.
Assuming they're not dead, I'll use these little guys to make me some #nanobodies!