#pyroptosis — Public Fediverse posts

How Viral Proteases Trigger Lytic Cell Death for Universal mRNA Therapy

#pyroptosis #virology #microbiology

https://davidojcius.blogspot.com/2026/07/how-viral-proteases-trigger-lytic-cell.html

How Viral Proteases Trigger Lytic Cell Death for Universal mRNA Therapy

#pyroptosis #virology #microbiology

https://davidojcius.blogspot.com/2026/07/how-viral-proteases-trigger-lytic-cell.html

Glibenclamide attenuates neuronal #pyroptosis by modulating KATP channels in the hippocampus of palmitic acid-induced lipotoxic mice

https://www.sciencedirect.com/science/article/pii/S2319417026000284 #OpenAccess #inflammasome #inflammation #immunology

The higher resolution, significantly improved apo crystal structure of mouse gasdermin D will be beneficial for structure-based drug-design approaches towards this important pharmacological target #Pyroptosis #Inflammation https://t.co/h2dHmhraZQ

Roles of pyroptosis and immune infiltration in aortic dissection. https://doi.org/10.3389/fmolb.2024.1277818 #AorticDissection #Bioinformatics #Pyroptosis #ImmuneInfiltration #Database

Roles of pyroptosis and immune infiltration in aortic dissection. https://doi.org/10.3389/fmolb.2024.1277818 #AorticDissection #Bioinformatics #Pyroptosis #ImmuneInfiltration #Database

What mediates necrosis-associated plasma membrane rupture during #ferroptosis?
Petr Broz and coworkers identify and early involvement of the #pyroptosis executor #Ninjurin-1
https://www.embopress.org/doi/full/10.1038/s44318-024-00055-y

What mediates necrosis-associated plasma membrane rupture during #ferroptosis?
Petr Broz and coworkers identify and early involvement of the #pyroptosis executor #Ninjurin-1
https://www.embopress.org/doi/full/10.1038/s44318-024-00055-y

#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm

#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm

#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm

#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm

#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm

#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Uptake-independent killing of macrophages by extracellular #Mycobacterium #tuberculosis aggregates

Chiara Toniolo et al show that Mtb aggregates evade #phagocytosis by inducing #macrophage #pyroptosis via a mechanism involving its type VII secretion system ESX-1 and surface lipid PDIM

https://www.embopress.org/doi/10.15252/embj.2023113490

Uptake-independent killing of macrophages by extracellular #Mycobacterium #tuberculosis aggregates

Chiara Toniolo et al show that Mtb aggregates evade #phagocytosis by inducing #macrophage #pyroptosis via a mechanism involving its type VII secretion system ESX-1 and surface lipid PDIM

https://www.embopress.org/doi/10.15252/embj.2023113490

@KannegantiLab @Achillebro

Welcome to the expanding cell death community on #scienceMastodon! 🙂

#celldeath #necroptosis #ferroptosis #pyroptosis

@SFB1403

Great that you joined #ScienceMastodon! 🙂🙂🙂

Welcome to the masters of regulated cell death! 💀 ☠️

#celldeath #necroptosis #ferroptosis #pyroptosis #apoptosis #cilia #Sciencefediverse #DFG #biology #plants