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#mycobacterium — Public Fediverse posts

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  1. Discovery of gene functions in #Mycobacterium #tuberculosis has been slow. This study tests a genome-wide barcoded #transposon library across 95 environmental conditions, providing a rich resource of new gene functions, including metabolic & resistance pathways @PLOSBiology plos.io/4vG0mz1

  2. Discovery of gene functions in #Mycobacterium #tuberculosis has been slow. This study tests a genome-wide barcoded #transposon library across 95 environmental conditions, providing a rich resource of new gene functions, including metabolic & resistance pathways @PLOSBiology plos.io/4vG0mz1

  3. Discovery of gene functions in #Mycobacterium #tuberculosis has been slow. This study tests a genome-wide barcoded #transposon library across 95 environmental conditions, providing a rich resource of new gene functions, including metabolic & resistance pathways @PLOSBiology plos.io/4vG0mz1

  4. Discovery of gene functions in #Mycobacterium #tuberculosis has been slow. This study tests a genome-wide barcoded #transposon library across 95 environmental conditions, providing a rich resource of new gene functions, including metabolic & resistance pathways @PLOSBiology plos.io/4vG0mz1

  5. Discovery of gene functions in #Mycobacterium #tuberculosis has been slow. This study tests a genome-wide barcoded #transposon library across 95 environmental conditions, providing a rich resource of new gene functions, including metabolic & resistance pathways @PLOSBiology plos.io/4vG0mz1

  6. ✨ What secret molecular partnership helps mycobacteria stay alive when conditions turn deadly?

    🔗 Structural modeling and biochemical characterization of MSMEG_0748, a MoxR ATPase from Mycobacterium smegmatis. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.11

    📚 CSBJ: csbj.org/

    #Mycobacterium #MoxR #ATPase #AlphaFold #StructuralBiology #Biophysics #Microbiology #MolecularModeling

  7. ✨ What secret molecular partnership helps mycobacteria stay alive when conditions turn deadly?

    🔗 Structural modeling and biochemical characterization of MSMEG_0748, a MoxR ATPase from Mycobacterium smegmatis. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.11

    📚 CSBJ: csbj.org/

    #Mycobacterium #MoxR #ATPase #AlphaFold #StructuralBiology #Biophysics #Microbiology #MolecularModeling

  8. ✨ What secret molecular partnership helps mycobacteria stay alive when conditions turn deadly?

    🔗 Structural modeling and biochemical characterization of MSMEG_0748, a MoxR ATPase from Mycobacterium smegmatis. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.11

    📚 CSBJ: csbj.org/

    #Mycobacterium #MoxR #ATPase #AlphaFold #StructuralBiology #Biophysics #Microbiology #MolecularModeling

  9. ✨ What secret molecular partnership helps mycobacteria stay alive when conditions turn deadly?

    🔗 Structural modeling and biochemical characterization of MSMEG_0748, a MoxR ATPase from Mycobacterium smegmatis. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.11

    📚 CSBJ: csbj.org/

    #Mycobacterium #MoxR #ATPase #AlphaFold #StructuralBiology #Biophysics #Microbiology #MolecularModeling

  10. #Antibiotika sind für #Pharma ein schlechtes Geschäft. So kennt man etwa BTZ-043, das den #Tuberkulose-Erreger #Mycobacterium tuberculosis effektiv ausschaltet, schon seit 20 Jahren. Doch Pharmafirmen interessieren sich nicht dafür … Karin Lauschke erzählt mehr: laborjournal.de/editorials/322

  11. #Antibiotika sind für #Pharma ein schlechtes Geschäft. So kennt man etwa BTZ-043, das den #Tuberkulose-Erreger #Mycobacterium tuberculosis effektiv ausschaltet, schon seit 20 Jahren. Doch Pharmafirmen interessieren sich nicht dafür … Karin Lauschke erzählt mehr: laborjournal.de/editorials/322

  12. #Antibiotika sind für #Pharma ein schlechtes Geschäft. So kennt man etwa BTZ-043, das den #Tuberkulose-Erreger #Mycobacterium tuberculosis effektiv ausschaltet, schon seit 20 Jahren. Doch Pharmafirmen interessieren sich nicht dafür … Karin Lauschke erzählt mehr: laborjournal.de/editorials/322

  13. #Antibiotika sind für #Pharma ein schlechtes Geschäft. So kennt man etwa BTZ-043, das den #Tuberkulose-Erreger #Mycobacterium tuberculosis effektiv ausschaltet, schon seit 20 Jahren. Doch Pharmafirmen interessieren sich nicht dafür … Karin Lauschke erzählt mehr: laborjournal.de/editorials/322

  14. #Antibiotika sind für #Pharma ein schlechtes Geschäft. So kennt man etwa BTZ-043, das den #Tuberkulose-Erreger #Mycobacterium tuberculosis effektiv ausschaltet, schon seit 20 Jahren. Doch Pharmafirmen interessieren sich nicht dafür … Karin Lauschke erzählt mehr: laborjournal.de/editorials/322

  15. #Mycobacterium vaccae in forests acts as antidepressant.

    #Phytoncides in trees are beneficial to parasympathetic nervous system; regeneration and relaxation.

    Reading Guerilla Green - Cookie Kalkair & Ophelia Damble - An (illustrated) urban Gardening Survival Guide.
    2021

    #GGGG #VandanaShiva #Fukuoka #Shinrinyoku #ForestBathing #RonFinley #MutualAid #Diversity

  16. #Mycobacterium vaccae in forests acts as antidepressant.

    #Phytoncides in trees are beneficial to parasympathetic nervous system; regeneration and relaxation.

    Reading Guerilla Green - Cookie Kalkair & Ophelia Damble - An (illustrated) urban Gardening Survival Guide.
    2021

    #GGGG #VandanaShiva #Fukuoka #Shinrinyoku #ForestBathing #RonFinley #MutualAid #Diversity

  17. #Mycobacterium vaccae in forests acts as antidepressant.

    #Phytoncides in trees are beneficial to parasympathetic nervous system; regeneration and relaxation.

    Reading Guerilla Green - Cookie Kalkair & Ophelia Damble - An (illustrated) urban Gardening Survival Guide.
    2021

    #GGGG #VandanaShiva #Fukuoka #Shinrinyoku #ForestBathing #RonFinley #MutualAid #Diversity

  18. #Mycobacterium vaccae in forests acts as antidepressant.

    #Phytoncides in trees are beneficial to parasympathetic nervous system; regeneration and relaxation.

    Reading Guerilla Green - Cookie Kalkair & Ophelia Damble - An (illustrated) urban Gardening Survival Guide.
    2021

    #GGGG #VandanaShiva #Fukuoka #Shinrinyoku #ForestBathing #RonFinley #MutualAid #Diversity

  19. "As methods for characterising pre-disease states evolve, the inference that all microbiologically positive #tuberculosis infections constitute disease will need re-evaluation."

    New research article in The Lancet Microbe

    PET-CT-guided characterisation of progressive, preclinical tuberculosis infection and its association with low-level circulating #Mycobacterium tuberculosis DNA in household contacts in Leicester, UK: a prospective cohort study

    thelancet.com/journals/lanmic/

    #TB

  20. "...our study provides the first insight into the performance of the catalogue in a real-world scenario. "

    New research article in The Lancet Microbe

    Role of the first WHO mutation catalogue in the diagnosis of antibiotic resistance in #Mycobacterium #tuberculosis in the Valencia Region, #Spain: a retrospective genomic analysis

    thelancet.com/journals/lanmic/

    #InfectiousDiseases #microbiology #TB #WGS #AMR #genomics #diagnostics

  21. Uptake-independent killing of macrophages by extracellular #Mycobacterium #tuberculosis aggregates

    Chiara Toniolo et al show that Mtb aggregates evade #phagocytosis by inducing #macrophage #pyroptosis via a mechanism involving its type VII secretion system ESX-1 and surface lipid PDIM

    embopress.org/doi/10.15252/emb

  22. Uptake-independent killing of macrophages by extracellular #Mycobacterium #tuberculosis aggregates

    Chiara Toniolo et al show that Mtb aggregates evade #phagocytosis by inducing #macrophage #pyroptosis via a mechanism involving its type VII secretion system ESX-1 and surface lipid PDIM

    embopress.org/doi/10.15252/emb

  23. Uptake-independent killing of macrophages by extracellular #Mycobacterium #tuberculosis aggregates

    Chiara Toniolo et al show that Mtb aggregates evade #phagocytosis by inducing #macrophage #pyroptosis via a mechanism involving its type VII secretion system ESX-1 and surface lipid PDIM

    embopress.org/doi/10.15252/emb

  24. Uptake-independent killing of macrophages by extracellular #Mycobacterium #tuberculosis aggregates

    Chiara Toniolo et al show that Mtb aggregates evade #phagocytosis by inducing #macrophage #pyroptosis via a mechanism involving its type VII secretion system ESX-1 and surface lipid PDIM

    embopress.org/doi/10.15252/emb

  25. "Thus, studies of MSMD (Mendelian susceptibility to mycobacterial disease ) have revealed that human antimycobacterial immunity is a genetically controlled quantitative trait: the lower the level of IFN-γ activity, the more severe the disease and the higher its penetrance"

    #immunology #InfetionImmunity #InfectiousDisease #mycobacterium #tuberculosis

    cell.com/cell/fulltext/S0092-8

  26. "Thus, studies of MSMD (Mendelian susceptibility to mycobacterial disease ) have revealed that human antimycobacterial immunity is a genetically controlled quantitative trait: the lower the level of IFN-γ activity, the more severe the disease and the higher its penetrance"

    #immunology #InfetionImmunity #InfectiousDisease #mycobacterium #tuberculosis

    cell.com/cell/fulltext/S0092-8

  27. "Thus, studies of MSMD (Mendelian susceptibility to mycobacterial disease ) have revealed that human antimycobacterial immunity is a genetically controlled quantitative trait: the lower the level of IFN-γ activity, the more severe the disease and the higher its penetrance"

    #immunology #InfetionImmunity #InfectiousDisease #mycobacterium #tuberculosis

    cell.com/cell/fulltext/S0092-8

  28. "Thus, studies of MSMD (Mendelian susceptibility to mycobacterial disease ) have revealed that human antimycobacterial immunity is a genetically controlled quantitative trait: the lower the level of IFN-γ activity, the more severe the disease and the higher its penetrance"

    #immunology #InfetionImmunity #InfectiousDisease #mycobacterium #tuberculosis

    cell.com/cell/fulltext/S0092-8

  29. So, I found out what nearly killed me today from the doctor. Starting treatment today for the next 6 - 8 weeks.

    #Mycobacterium #FishKeeping #Aquarium

    en.wikipedia.org/wiki/Mycobact

  30. So, I found out what nearly killed me today from the doctor. Starting treatment today for the next 6 - 8 weeks.

    #Mycobacterium #FishKeeping #Aquarium

    en.wikipedia.org/wiki/Mycobact

  31. So, I found out what nearly killed me today from the doctor. Starting treatment today for the next 6 - 8 weeks.

    #Mycobacterium #FishKeeping #Aquarium

    en.wikipedia.org/wiki/Mycobact

  32. So, I found out what nearly killed me today from the doctor. Starting treatment today for the next 6 - 8 weeks.

    #Mycobacterium #FishKeeping #Aquarium

    en.wikipedia.org/wiki/Mycobact

  33. My latest column for #NatureMedicine is a look at early human results of a new class of #antibiotics for #tuberculosis

    The mechanism of action is essentially to clog the #mycobacterium's tRNA synthetase - the result of two decades of research on boron-based compounds.

    #IDMastodon #DrugDevelopment
    #antibioticresistance

    nature.com/articles/d41591-022

  34. My latest column for #NatureMedicine is a look at early human results of a new class of #antibiotics for #tuberculosis

    The mechanism of action is essentially to clog the #mycobacterium's tRNA synthetase - the result of two decades of research on boron-based compounds.

    #IDMastodon #DrugDevelopment
    #antibioticresistance

    nature.com/articles/d41591-022

  35. My latest column for #NatureMedicine is a look at early human results of a new class of #antibiotics for #tuberculosis

    The mechanism of action is essentially to clog the #mycobacterium's tRNA synthetase - the result of two decades of research on boron-based compounds.

    #IDMastodon #DrugDevelopment
    #antibioticresistance

    nature.com/articles/d41591-022

  36. My latest column for #NatureMedicine is a look at early human results of a new class of #antibiotics for #tuberculosis

    The mechanism of action is essentially to clog the #mycobacterium's tRNA synthetase - the result of two decades of research on boron-based compounds.

    #IDMastodon #DrugDevelopment
    #antibioticresistance

    nature.com/articles/d41591-022