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#caspase — Public Fediverse posts

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  1. Some executioner caspases also have non-apoptotic functions. This study shows that sublethal executioner #caspase activation enhances #hepatocyte proliferation via JAK/STAT3 signaling, revealing a role for executioner caspases in promoting liver #regeneration @PLOSBiology plos.io/3JEsH57

  2. Some executioner caspases also have non-apoptotic functions. This study shows that sublethal executioner #caspase activation enhances #hepatocyte proliferation via JAK/STAT3 signaling, revealing a role for executioner caspases in promoting liver #regeneration @PLOSBiology plos.io/3JEsH57

  3. Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells #plosbiology plos.io/41xfLVm

  4. Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells #plosbiology plos.io/41xfLVm

  5. An intracellular #LiquidCondensate formed in plants by #LipidTransferase SFH8 associates with membranes; SFH8 cleavage by #Caspase-like protease ESP turns it into a solid filament that can modulate root development @Panosmoschou @Chenliu06 &co #PLOSBiology plos.io/3sZkIY0

  6. An intracellular #LiquidCondensate formed in plants by #LipidTransferase SFH8 associates with membranes; SFH8 cleavage by #Caspase-like protease ESP turns it into a solid filament that can modulate root development @Panosmoschou @Chenliu06 &co #PLOSBiology plos.io/3sZkIY0

  7. ER stress induces #caspase-2-tBID-GSDME-dependent cell death in neurons lytically infected with #herpes simplex #virus type 2

    #HSV type 2 infection promotes #neuronal #celldeath and #inflammatory responses via #ERstress-dependent #gasdermin E activation.

    Søren Paludan and colleagues

    embopress.org/doi/full/10.1525

  8. ER stress induces #caspase-2-tBID-GSDME-dependent cell death in neurons lytically infected with #herpes simplex #virus type 2

    #HSV type 2 infection promotes #neuronal #celldeath and #inflammatory responses via #ERstress-dependent #gasdermin E activation.

    Søren Paludan and colleagues

    embopress.org/doi/full/10.1525

  9. Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology plos.io/3p6klcm

  10. Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology plos.io/3p6klcm

  11. Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology plos.io/3p6klcm

  12. Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology plos.io/3p6klcm

  13. Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology plos.io/3p6klcm

  14. Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology plos.io/3p6klcm

  15. The findings of this study open up possibilities for further research on the role of ATP in apoptosis, as well as potential therapeutic targets for controlling cell death.

    #ATP #Cell #CellDeath #Apoptosis #Caspase-3 #Pannexin-1 #Metabolism #FRET #Biosensors