#ferroptosis — Public Fediverse posts

Experiments with the nematode *Caenorhabditis elegans* found that feeding with a magnetotactic bacterium reduces ferroptosis--a type of programmed cell death that is dependent on iron--and extended lifespan by as much as 40%. Neural function was also improved in older worms.

Summary: https://scitechdaily.com/magnetic-bacterium-extends-lifespan-by-43-in-surprising-anti-aging-study/

Original paper: https://www.sciencedirect.com/science/article/abs/pii/S0891584926009056

#Science #Nematode #Lifespan #Ferroptosis

#OddChainFattyAcids #PentadecanoicAcid #C15 #Dairy #Ferroptosis #SheepDairy #CowButter #healthyageing #healthyaging #wellnessthatworks #wellnessblogger #emotionalwellbeing #wellnesslifestyle #FattyAcidsResearch #HealthResearch #Nutrition https://mastodon.social/@biohackingpathway/116700749831927789

Vitamin B2 Supports Cancer Cells by Protecting Them from Ferroptosis, Study Finds

📰 Original title: Scientists discover vitamin B2 may help cancer cells survive

🤖 IA: It's clickbait ⚠️
👥 Users: It's clickbait ⚠️

View full AI summary: https://en.killbait.com/vitamin-b2-supports-cancer-cells-by-protecting-them-from-ferroptosis-study-finds.html?utm_source=mastodon_world&utm_medium=social&utm_campaign=killbait.mastodon_world

#health #cancer #vitaminb2 #ferroptosis

Researchers show how a defect in the #enzyme #GPX4 can trigger #ferroptosis and lead to neuronal loss in certain forms of #dementia. The work provides new insights into cell protection mechanisms: http://go.tum.de/142494

📷T.Orschmann & S. Lorenz

🧪 Breakthrough in breast cancer research

Researchers at the University of Liège identified ferroptosis—a form of programmed cell death—as a potential treatment for HR+ HER2- metastatic breast cancer resistant to CDK4/6 inhibitors & hormone therapy.

Their findings show ferroptosis inducers can target resistant cells, paving the way for precision medicine. Clinical trials could be next!

https://www.giga.uliege.be/cms/c_13401286/en/new-research-shows-ferroptosis-inducers-can-reverse-resistance-of-the-luminal-metastatic-hormone-positive-breast-cancer

#BreastCancerResearch #Ferroptosis #Oncology #ULiege

Cobalt Complex Induces Programmed Cell Death against Cancer

Co(III) polypyridine sulfasalazine complex can act as a ferroptosis inducer to kill cancer cells

https://www.chemistryviews.org/cobalt-complex-induces-programmed-cell-death-against-cancer/

#ferroptosis #cancertreatment #programmedcelldeath #chemistry

What mediates necrosis-associated plasma membrane rupture during #ferroptosis?
Petr Broz and coworkers identify and early involvement of the #pyroptosis executor #Ninjurin-1
https://www.embopress.org/doi/full/10.1038/s44318-024-00055-y

The discovery that a #lipid helps induce #cell #death could improve treatments for certain #cancers and #neurodegenerative diseases. Columbia researchers have found that a rare type of lipid is a key driver of #ferroptosis, a form of cell death
#Biology #sflorg
https://www.sflorg.com/2024/02/bio02152402.html

#CallforProposals for the 2nd funding period in the Priority Programme "#Ferroptosis: from Molecular Basics to Clinical Applications". Goal is to support highly collaborative projects at the forefront of ferroptosis #research. Details: ⬇️
https://www.dfg.de/foerderung/info_wissenschaft/info_wissenschaft_23_109/index.html

Inducing #ferroptosis is a key approach to inhibiting #tumor progression, but how is it regulated? Study shows that #HBP1 #nanoparticles enter tumor cells, inducing ferroptosis & inhibiting #malignancy by regulating the HBP1-UHRF1-CDO1 pathway #PLOSBiology https://plos.io/3NEILSO