#naltrexone — Public Fediverse posts

interesting comment from Dr Younger:

"Thanks for bringing up that issue! There has been a ton of misinformation on "regular" prescription naltrexone, even among experts. If you look it up on Google, it will tell you that naltrexone is a racemic mixture of l- and d- forms. Any many, if not most, papers do the same. They are all wrong. If you pull up the CoA for manufactured naltrexone, you will see it has a -192 degree optical rotation. All commercial naltrexone is levo only. Levo hits both opioid and TLR4 receptors (among other things), while dextro only hits the TLR4 receptor. I don't know how to fix the misinformation online because now AI is pulling its info from incorrect sources. So it is almost impossible to get to the right source unless someone already knows what they are doing (e.g., accessing the manufacturer CoA's). - Jarred Younger"

https://www.youtube.com/watch?v=KpsK6RmqLNI&lc=Ugz8z9zuskpLiMGay-N4AaABAg.APdUyq5hqymAPdY5kV5qVu

#naltrexone #TLR4

interesting comment from Dr Younger:

"Thanks for bringing up that issue! There has been a ton of misinformation on "regular" prescription naltrexone, even among experts. If you look it up on Google, it will tell you that naltrexone is a racemic mixture of l- and d- forms. Any many, if not most, papers do the same. They are all wrong. If you pull up the CoA for manufactured naltrexone, you will see it has a -192 degree optical rotation. All commercial naltrexone is levo only. Levo hits both opioid and TLR4 receptors (among other things), while dextro only hits the TLR4 receptor. I don't know how to fix the misinformation online because now AI is pulling its info from incorrect sources. So it is almost impossible to get to the right source unless someone already knows what they are doing (e.g., accessing the manufacturer CoA's). - Jarred Younger"

https://www.youtube.com/watch?v=KpsK6RmqLNI&lc=Ugz8z9zuskpLiMGay-N4AaABAg.APdUyq5hqymAPdY5kV5qVu

#naltrexone #TLR4

078 - How I am going to fight brain inflammation | Jarred Younger, PhD
uploaded Nov 17, 2025
https://youtu.be/KpsK6RmqLNI

Dr. Younger shares his intention to manufacture and test dextro-naltrexone in a clinical trial.

😀

#naltrexone #LDN #DextroNaltrexone #neroinflammation #neuroscience #immunology #MECFS #TLR4

078 - How I am going to fight brain inflammation | Jarred Younger, PhD
uploaded Nov 17, 2025
https://youtu.be/KpsK6RmqLNI

Dr. Younger shares his intention to manufacture and test dextro-naltrexone in a clinical trial.

😀

#naltrexone #LDN #DextroNaltrexone #neroinflammation #neuroscience #immunology #MECFS #TLR4

https://pubmed.ncbi.nlm.nih.gov/39101571/ Off-Label Use of Lamotrigine and Naltrexone in the Treatment of Ketamine Use Disorder: A Case Report #ketamine #substanceUseDisorder #lamotrigine #naltrexone #addiction #substanceuse #recovery

Griffith University researchers to trial naltrexone on Long COVID and MECFS patients.

#LongCOVID #MECFS #naltrexone @auscovid19

Source: https://www.abc.net.au/news/2024-05-07/qld-griffith-university-trial-naltrexone-long-covid/103800050

Griffith University researchers to trial naltrexone on Long COVID and MECFS patients.

#LongCOVID #MECFS #naltrexone @auscovid19

Source: https://www.abc.net.au/news/2024-05-07/qld-griffith-university-trial-naltrexone-long-covid/103800050

" #worldwide #alcohol abuse kills more people than #hiv nearly 3.3 million per year. Profiling recovering alcoholics, medical professionals and justice practitioners, this investigation #exposes the benefits of a little-known drug #Naltrexone […]"

https://www.imdb.com/title/tt3427772/

#One Little #Pill

#movierecommendations

" #worldwide #alcohol abuse kills more people than #hiv nearly 3.3 million per year. Profiling recovering alcoholics, medical professionals and justice practitioners, this investigation #exposes the benefits of a little-known drug #Naltrexone […]"

https://www.imdb.com/title/tt3427772/

#One Little #Pill

#movierecommendations

Hey #spoonies I’ve got a diagnosis of #CFS aka #MyalgicEncephalomyelitis and was recently prescribed #naltrexone for off-label, micro-dose use in treating chronic pain. Working my way up to a dose of <10% of regular use, starting at 1 mL in solution. Just moved up to 1.5 after taking an extra week on the initial dose b/c of sleep disruption, and now I’ve got that plus all-over body aches, headache, and sore throat. Anyone else willing to share experiences?

Hey #spoonies I’ve got a diagnosis of #CFS aka #MyalgicEncephalomyelitis and was recently prescribed #naltrexone for off-label, micro-dose use in treating chronic pain. Working my way up to a dose of <10% of regular use, starting at 1 mL in solution. Just moved up to 1.5 after taking an extra week on the initial dose b/c of sleep disruption, and now I’ve got that plus all-over body aches, headache, and sore throat. Anyone else willing to share experiences?

Here's hoping that low dosage naltrexone does what people have been saying it does. Fingers crossed 🤞Anyone out there have good results? The pharmacist said to give it at least a month before deciding.

#mecfs #LDN #longCovid #naltrexone #lowDosageNaltrexone

#introduction

Lazy but curious (curious but lazy), cog in the wheel, armchair wannabe researcher, addictions doc, pharmacologist, national board of www.sitd.it

I'm interested in
#AddictionMedicine
#Addictions
#Cocaine
#Methadone
#Buprenorphine
#Naltrexone
#RepurposedDrugs
#Covid-19

Orcid 0000-0002-6809-4096

#introduction

Lazy but curious (curious but lazy), cog in the wheel, armchair wannabe researcher, addictions doc, pharmacologist, national board of www.sitd.it

I'm interested in
#AddictionMedicine
#Addictions
#Cocaine
#Methadone
#Buprenorphine
#Naltrexone
#RepurposedDrugs
#Covid-19

Orcid 0000-0002-6809-4096