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CW: re: DIY (homebrew) feminising GAHT (HRT) weekly injection (~18 hours late)
@iouring Hi Lucielle. We appreciate that you're almost certainly coming from a place of good faith with your thoughts there. However, we do want to gently and kindly (without any meaninghighlight how your points are coming across to us 🥺
- That we lack knowledge on the topic of GAHT, particularly different esters.
- That homebrew / DIY GAHT is unsafe.
- That perfectly-fine estradiol level ranges are unreasonable or high.
We don't know if you intended your thoughts to come across this way. It might be a language or culture barrier. Nonetheless, we want to try to clarify some misconceptions you seem to have.
Esters within the homebrew community
Cypionate
This has fallen out of fashion especially where it has largely been replaced by enanthate, which is better-suited for weekly injections. The raws are often slightly cheaper than enanthate, but if you're buying pre-made, it will often cost more. Its only real viable use is if you are able to get prescription estradiol cypionate.
Valerate
This is considered the least-common ester within the homebrew community, due to:
- Its short elimination half-life making it only well-suited for injections twice-weekly or every 5 days.
- It causing higher peaks and lower troughs.
It's mostly only used by people able to get estradiol valerate on prescription, but it is sadly commonly prescribed weekly at non-ideal doses by underqualified medical staff.
Undecylate
This is commonly compounded at both 50 mg/mL and 100 mg/mL now, making it well-suited to higher-volume, less-frequent injections.
It is less-commonly used due to a mixture of factors, including:
- The longer elimination half-life necessitating a larger loading dose.
- The higher cost of the raws.
- It requiring a different carrier formulation for higher concentrations.
- 50 mg/mL can typically be done in MCT or grapeseed oil with 2% benzyl alcohol, but 100 mg/mL may require up to 40% benzyl benzoate to keep the ester suspended.
Estradiol levels and ranges
Neither 1,000 or 2,000 pmol/L are particularly unreasonably high. It is sadly only considered so for trans+ fems by transmisogynistic medical institutions and systems.
Consider the guidance given by WPATH SOC8. This suggests an arbitrary, pseudoscientific estradiol range of 100 to 200 pg/mL (367 to 734 pmol/L) for feminising GAHT. This is predicated on the myths that:
- Merely having a higher estradiol level increases your VTE risk, which is not true.
- Having a higher estradiol level increases breast cancer risk, which again is not true.
This has sadly led to medical institutions trying to use median figures for their estradiol ranges, or using arbitrarily-rounded lower ranges. The NHS, for example, uses a whole host of sub-optimal estradiol ranges for feminising GAHT, irrespective of the negative consequences on the wellbeing of patients.
Common guidance also ignores the well-recognised "monotherapy" model, whereby a higher estradiol trough is maintained in order to apply negative feedback to the HPG axis. This negative feedback causes a series of reactions that results in total gonadal (testicular) suppression without the need for other meds (e.g., GnRH agonists; GnRH antagonists; anti-androgens).
It's worth noting that testosterone monotherapy, which is the most-common method of masculinising GAHT, uses the same principle of applying negative feedback to the HPG axis to cause gonadal (ovarian) suppression.
In terms of estradiol ranges, it is much more-helpful to look at common estradiol ranges of cis women during menstruation than to go by median ranges. Figures vary wildly, but studies have shown peaks of around 650 pg/mL to 750 pg/mL, which corresponds to ~2,386 to ~2,754 pmol/L.
Even the misogynistic NHS gives level ranges like these:
- Mid-luteal: 180 - 1,068 pmol/L
- Peri-ovulatory: 349 - 1,590 pmol/L
Blood tests
We totally agree that blood tests (as regularly as affordable or even available) should be carried out to measure your estradiol trough to ensure that it's sufficiently high, and to ensure that your testosterone level is fully suppressed.
Resources you might find useful
- DIY HRT Wiki 2.0
- HRT4All
- You may need to answer a quiz to access it, after which it'll take you to their homepage.
- If you have troubles accessing in one browser, clear the site data and/or try a different browser.
- Wiki Trans (en français)
#trans #TransDIY #TransGAHT #mythbusting #TransFemHRT #TransFemGAHT #queer #LGBTQ+ #LGBTQIA+ #transgender #FeminisingHRT #FeminisingGAHT
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"Mes 14 ans" par Lucie Mikaélian
Dans les couilles sur la table
Très riche !
#bingehttps://www.binge.audio/podcast/le-coeur-sur-la-table/mes-14-ans-par-lucie-mikaelian
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Rico con Anna luciendo el mismo peinado #DogsOnMastodon
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🔴 Appel de Lucie Castets : l'APRÈS répond présente avec enthousiasme !
Nous appelons toutes les forces de gauche et écologistes à se retrouver le 2 juillet.
#NouveauFrontPopulaire #NFP #LucieCastets #Lapres
https://www.l-apres.fr/pour_une_gauche_unie_et_victorieuse_en_2027
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🇫🇷🇪🇺 Présidentielle 2027 : Lucie Castets appelle à «une primaire des gauches la plus large possible» https://www.election-politique.com/index.php?display=M
#VuDansLaPresse #newspaper #Politique #politics #International #France #LucieCastets #Presidentielle2027
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Unknown by Lucien Clergue, 1998
#Art #CreativePhotography #FineArtPhotography #PortraitPhotography #ModelPhotography #BodyPositivity #ArtisticExpression #BeautyInArt #FashionPhotography #BlackAndWhite #Monochrome #BWPhotography #BlackAndWhitePhotography #bnw #cloudflareFree
RT: https://mastodon.social/users/Sneakpeaking/statuses/114283983252258361 -
@Old_IT_geek @luciedigitalni @fixatedpersonsunit @InsurgoFormica a blue-ringed octopus killed someone the other day and then there’s the soil bacteria that’s killed a dozen this year.
#Melioidosis #DeadlyAustralia #InvasionProof #JellyFish #Octopus #China #Australia
https://www.abc.net.au/news/2025-02-25/melioidosis-death-toll-rises-in-queensland/104979406
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Dziś przypada rocznica urodzin Luciena Pissarro (1863–1944), wybitnego malarza impresjonistycznego i neoimpresjonistycznego, grafika i ilustratora. Był synem Camille'a Pissarro i założycielem Eragny Press, ważnego wydawnictwa w historii ilustracji książkowej. Jego twórczość to ponad 550 pejzaży Anglii i Francji, które przyczyniły się do popularyzacji impresjonizmu w Wielkiej Brytanii. #LucienPissarro #Sztuka #Impresjonizm #Neoimpresjonizm (fot. Wikipedia)
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Pierrat-Pajot Lucie – Les mystères de Larispem 1 Le sang jamais n’oublie
#Bookstagram #Bookstagramfrance #Lespassionsdaely #blog #bloglitteraire #cli13 #VidetaPal #steampunk Série : Les mystères de LarispemTome 1 Le sang jamais n'oublieNombre de pages : 320 pagesEdition : Gallimard jeunesse Résumé Larispem, 1899. Dans cette Cité-État indépendante où les bouchers constituent la caste forte d'un régime populiste, trois destins se croisent : Liberté, la mécanicienne hors…
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‘Emily In Paris’ Actor Lucien Laviscount Joins Kiefer Sutherland In ‘Tinsel Town’
#Casting #KieferSutherland #LucienLaviscount #TinselTownhttps://deadline.com/2025/02/lucien-laviscount-kiefer-sutherland-tinsel-town-1236288183/
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‘Emily In Paris’: Lucien Laviscount To Return As Series Regular In Season 5
#Casting #News #EmilyinParis #LucienLaviscounthttps://deadline.com/2025/01/emily-in-paris-lucien-laviscount-return-season-5-alfie-1236262639/
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#LyesLouffok #ClaireNguyen #LucieCastets et #DanielleSimonnet au premier rang d'un groupe de militant.e.s à #Grenoble le 16 janvier
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#LyesLouffok #ClaireNguyen #LucieCastets et #DanielleSimonnet au premier rang d'un groupe de militant.e.s à #Grenoble le 16 janvier
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#LyesLouffok #ClaireNguyen #LucieCastets et #DanielleSimonnet au premier rang d'un groupe de militant.e.s à #Grenoble le 16 janvier
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#LyesLouffok #ClaireNguyen #LucieCastets et #DanielleSimonnet au premier rang d'un groupe de militant.e.s à #Grenoble le 16 janvier
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#LyesLouffok #ClaireNguyen #LucieCastets et #DanielleSimonnet au premier rang d'un groupe de militant.e.s à #Grenoble le 16 janvier
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Gagnons ensemble/Lucie Castets Marine Tondelier
Gagnons ensemble
https://mcinformactions.net/gagnons-ensemble
#electionpresidentielle #gauche -
SUPER #gagnonsensemble avec #LucieCastetsPremiereMinistre 🤩
MAIS :
site web hébergé par #nationbuilder 🤮 NON ‼️
Extrait de #gagnonsensemble
"discours populistes gagnent du terrain et mettent à l’épreuve nos démocraties. Beaucoup de pays ont déjà basculé dans la réaction, contre l’écologie, contre le progrès, contre les libertés."
#nationbuilder = #capitalisme_de_surveillance = #technosolutionnisme 🤦⚠️
SOLUTIONS :
#communsnumeriques 🤩
#logiciellibre 😻
#chatonsorg 😺 -
SUPER #gagnonsensemble avec #LucieCastetsPremiereMinistre 🤩
MAIS :
site web hébergé par #nationbuilder 🤮 NON ‼️
Extrait de #gagnonsensemble
"discours populistes gagnent du terrain et mettent à l’épreuve nos démocraties. Beaucoup de pays ont déjà basculé dans la réaction, contre l’écologie, contre le progrès, contre les libertés."
#nationbuilder = #capitalisme_de_surveillance = #technosolutionnisme 🤦⚠️
SOLUTIONS :
#communsnumeriques 🤩
#logiciellibre 😻
#chatonsorg 😺 -
SUPER #gagnonsensemble avec #LucieCastetsPremiereMinistre 🤩
MAIS :
site web hébergé par #nationbuilder 🤮 NON ‼️
Extrait de #gagnonsensemble
"discours populistes gagnent du terrain et mettent à l’épreuve nos démocraties. Beaucoup de pays ont déjà basculé dans la réaction, contre l’écologie, contre le progrès, contre les libertés."
#nationbuilder = #capitalisme_de_surveillance = #technosolutionnisme 🤦⚠️
SOLUTIONS :
#communsnumeriques 🤩
#logiciellibre 😻
#chatonsorg 😺 -
SUPER #gagnonsensemble avec #LucieCastetsPremiereMinistre 🤩
MAIS :
site web hébergé par #nationbuilder 🤮 NON ‼️
Extrait de #gagnonsensemble
"discours populistes gagnent du terrain et mettent à l’épreuve nos démocraties. Beaucoup de pays ont déjà basculé dans la réaction, contre l’écologie, contre le progrès, contre les libertés."
#nationbuilder = #capitalisme_de_surveillance = #technosolutionnisme 🤦⚠️
SOLUTIONS :
#communsnumeriques 🤩
#logiciellibre 😻
#chatonsorg 😺 -
SUPER #gagnonsensemble avec #LucieCastetsPremiereMinistre 🤩
MAIS :
site web hébergé par #nationbuilder 🤮 NON ‼️
Extrait de #gagnonsensemble
"discours populistes gagnent du terrain et mettent à l’épreuve nos démocraties. Beaucoup de pays ont déjà basculé dans la réaction, contre l’écologie, contre le progrès, contre les libertés."
#nationbuilder = #capitalisme_de_surveillance = #technosolutionnisme 🤦⚠️
SOLUTIONS :
#communsnumeriques 🤩
#logiciellibre 😻
#chatonsorg 😺 -
🇫🇷💪 Movimiento inesperado: Lucie Castets (candidata del NFP a Primera Ministra y Marine Tondelier (Ecologistas) lanzan un comunicado conjunto en el que ponen en marcha el proyecto Gagnons ensemble (genemos juntos) para “organizarnos y construir un proyecto común a toda la izquierda, las fuerzas del progreso y los ecologistas”.
https://www.gagnons-ensemble.fr/
#izquierdafrancesa -
☢️ Dana Drábová u Lucie Výborné.👇
A je to výborné.Putin využívá hrůzy z jaderných zbraní, míní Dana Drábová
🎙️#irozhlas
https://www.irozhlas.cz/zpravy-domov/zadne-cervene-tlacitko-neexistuje-putin-vyuziva-hruzy-z-jadernych-zbrani-mini_2411251840_mst -
https://freeresources.luciencanton.com/
Great article from a Certified Emergency Manager (CEM) Lucien Canton regarding federal disaster reform.
#fema #DisasterRecovery #EMGToot #EmergencyManagement #Disaster #USPolicy #DisasterPreparedness #HazardMitigation
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🚴♂️ Joop Zoetemelk y Lucien van Impe.
#Cycling #CyclingLegends #Ciclismo #Cyclisme #Bike #Bicicleta #Vélo #Bicicletta #Sport #Deporte #Thursday #Jueves #Jeudi #Giovedì #ForYou #ParaTi #DedicadoaTi #RamónCabezas #RamónCabezasEzquerra #CristóbalCabezas #CristóbalCabezasMartín
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🚴♂️ Joop Zoetemelk y Lucien van Impe.
#Cycling #CyclingLegends #Ciclismo #Cyclisme #Bike #Bicicleta #Vélo #Bicicletta #Sport #Deporte #Thursday #Jueves #Jeudi #Giovedì #ForYou #ParaTi #DedicadoaTi #RamónCabezas #RamónCabezasEzquerra #CristóbalCabezas #CristóbalCabezasMartín
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🚴♂️ Joop Zoetemelk y Lucien van Impe.
#Cycling #CyclingLegends #Ciclismo #Cyclisme #Bike #Bicicleta #Vélo #Bicicletta #Sport #Deporte #Thursday #Jueves #Jeudi #Giovedì #ForYou #ParaTi #DedicadoaTi #RamónCabezas #RamónCabezasEzquerra #CristóbalCabezas #CristóbalCabezasMartín
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Interview de Lucie #Castets dans Politis : « Emmanuel Macron ne veut pas améliorer la vie des gens » #NFP #LucieCastets1°Ministre #Gauche #République #Démocratie https://www.politis.fr/articles/2024/08/entretien-lucie-castets-nfp-macron-ne-veut-pas-ameliorer-la-vie-des-gens/
