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#totalsynthesis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #totalsynthesis, aggregated by home.social.

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  1. A bit late to the party, but still interesting. In 2023 Yong Qin and co-workers from Sichuan #University in #China published in #JACS the first #totalsynthesis of the terpene garryine.

    The total synthesis heavily relies on [Pd] catalyzed cross couplings including a enantioselective variant of an intramolecular Heck coupling.

    The draft has been added to my page some years ago, but only finished today.

    organicchemistry.eu/books/tota

    #chemistry #science #organicchemistry

  2. A bit late to the party, but still interesting. In 2023 Yong Qin and co-workers from Sichuan #University in #China published in #JACS the first #totalsynthesis of the terpene garryine.

    The total synthesis heavily relies on [Pd] catalyzed cross couplings including a enantioselective variant of an intramolecular Heck coupling.

    The draft has been added to my page some years ago, but only finished today.

    organicchemistry.eu/books/tota

    #chemistry #science #organicchemistry

  3. A bit late to the party, but still interesting. In 2023 Yong Qin and co-workers from Sichuan #University in #China published in #JACS the first #totalsynthesis of the terpene garryine.

    The total synthesis heavily relies on [Pd] catalyzed cross couplings including a enantioselective variant of an intramolecular Heck coupling.

    The draft has been added to my page some years ago, but only finished today.

    organicchemistry.eu/books/tota

    #chemistry #science #organicchemistry

  4. A bit late to the party, but still interesting. In 2023 Yong Qin and co-workers from Sichuan #University in #China published in #JACS the first #totalsynthesis of the terpene garryine.

    The total synthesis heavily relies on [Pd] catalyzed cross couplings including a enantioselective variant of an intramolecular Heck coupling.

    The draft has been added to my page some years ago, but only finished today.

    organicchemistry.eu/books/tota

    #chemistry #science #organicchemistry

  5. A bit late to the party, but still interesting. In 2023 Yong Qin and co-workers from Sichuan #University in #China published in #JACS the first #totalsynthesis of the terpene garryine.

    The total synthesis heavily relies on [Pd] catalyzed cross couplings including a enantioselective variant of an intramolecular Heck coupling.

    The draft has been added to my page some years ago, but only finished today.

    organicchemistry.eu/books/tota

    #chemistry #science #organicchemistry

  6. Mingji Dai (Emroy University, USA) recently published the first #totalsynthesis of the #alkaloid stemocurtisine in the journal #JACS (10.1021/jacs.6c12593) using a palladium catalysed carbonylation for lactone formation.

    I summarised his synthetic route on my collection of total syntheses and added two exercises for advanced #chemistry #students

    Check out here: organicchemistry.eu/books/tota

    #science #research

  7. Mingji Dai (Emroy University, USA) recently published the first #totalsynthesis of the #alkaloid stemocurtisine in the journal #JACS (10.1021/jacs.6c12593) using a palladium catalysed carbonylation for lactone formation.

    I summarised his synthetic route on my collection of total syntheses and added two exercises for advanced #chemistry #students

    Check out here: organicchemistry.eu/books/tota

    #science #research

  8. Mingji Dai (Emroy University, USA) recently published the first #totalsynthesis of the #alkaloid stemocurtisine in the journal #JACS (10.1021/jacs.6c12593) using a palladium catalysed carbonylation for lactone formation.

    I summarised his synthetic route on my collection of total syntheses and added two exercises for advanced #chemistry #students

    Check out here: organicchemistry.eu/books/tota

    #science #research

  9. Mingji Dai (Emroy University, USA) recently published the first #totalsynthesis of the #alkaloid stemocurtisine in the journal #JACS (10.1021/jacs.6c12593) using a palladium catalysed carbonylation for lactone formation.

    I summarised his synthetic route on my collection of total syntheses and added two exercises for advanced #chemistry #students

    Check out here: organicchemistry.eu/books/tota

    #science #research

  10. Mingji Dai (Emroy University, USA) recently published the first #totalsynthesis of the #alkaloid stemocurtisine in the journal #JACS (10.1021/jacs.6c12593) using a palladium catalysed carbonylation for lactone formation.

    I summarised his synthetic route on my collection of total syntheses and added two exercises for advanced #chemistry #students

    Check out here: organicchemistry.eu/books/tota

    #science #research

  11. 🎁 Happy 80th birthday to K. C. Nicolaou—master of “the art of total synthesis”, whose landmark syntheses of Calicheamicin, Taxol, Brevetoxin B, Epothilone, and Vancomycin helped shape modern organic chemistry. #TotalSynthesis #OrganicChemistry

  12. 🎁 Happy 80th birthday to K. C. Nicolaou—master of “the art of total synthesis”, whose landmark syntheses of Calicheamicin, Taxol, Brevetoxin B, Epothilone, and Vancomycin helped shape modern organic chemistry. #TotalSynthesis #OrganicChemistry

  13. 🎁 Happy 80th birthday to K. C. Nicolaou—master of “the art of total synthesis”, whose landmark syntheses of Calicheamicin, Taxol, Brevetoxin B, Epothilone, and Vancomycin helped shape modern organic chemistry. #TotalSynthesis #OrganicChemistry

  14. 🎁 Happy 80th birthday to K. C. Nicolaou—master of “the art of total synthesis”, whose landmark syntheses of Calicheamicin, Taxol, Brevetoxin B, Epothilone, and Vancomycin helped shape modern organic chemistry. #TotalSynthesis #OrganicChemistry

  15. 🎁 Happy 80th birthday to K. C. Nicolaou—master of “the art of total synthesis”, whose landmark syntheses of Calicheamicin, Taxol, Brevetoxin B, Epothilone, and Vancomycin helped shape modern organic chemistry. #TotalSynthesis #OrganicChemistry

  16. 🎁HBT Paul Knochel (LMU Munich), who turns 70 today—unbelievable knowing his charming boyish appeal. Developing new synthetic methods, in particular based on organometallic compounds, and applying them in the #TotalSynthesis of natural products has become a hallmark of the Knochel group.

  17. 🎁HBT Paul Knochel (LMU Munich), who turns 70 today—unbelievable knowing his charming boyish appeal. Developing new synthetic methods, in particular based on organometallic compounds, and applying them in the #TotalSynthesis of natural products has become a hallmark of the Knochel group.

  18. 🎁HBT Paul Knochel (LMU Munich), who turns 70 today—unbelievable knowing his charming boyish appeal. Developing new synthetic methods, in particular based on organometallic compounds, and applying them in the #TotalSynthesis of natural products has become a hallmark of the Knochel group.

  19. Novel enantioselective of rubriflordilactone B by Gui and colleagues from the Chinese Academy of Science published in
    This is already the second total synthesis of this group, with an interesting reaction cascade as the key reaction in this process.

    pubs.acs.org/doi/10.1021/jacs.

  20. Novel enantioselective #synthesis of rubriflordilactone B by Gui and colleagues from the Chinese Academy of Science published in #JACS
    This is already the second total synthesis of this group, with an interesting reaction cascade as the key reaction in this process.

    #chemistry #science #totalsynthesis

    pubs.acs.org/doi/10.1021/jacs.

  21. Novel enantioselective #synthesis of rubriflordilactone B by Gui and colleagues from the Chinese Academy of Science published in #JACS
    This is already the second total synthesis of this group, with an interesting reaction cascade as the key reaction in this process.

    #chemistry #science #totalsynthesis

    pubs.acs.org/doi/10.1021/jacs.

  22. Novel enantioselective #synthesis of rubriflordilactone B by Gui and colleagues from the Chinese Academy of Science published in #JACS
    This is already the second total synthesis of this group, with an interesting reaction cascade as the key reaction in this process.

    #chemistry #science #totalsynthesis

    pubs.acs.org/doi/10.1021/jacs.

  23. Novel enantioselective #synthesis of rubriflordilactone B by Gui and colleagues from the Chinese Academy of Science published in #JACS
    This is already the second total synthesis of this group, with an interesting reaction cascade as the key reaction in this process.

    #chemistry #science #totalsynthesis

    pubs.acs.org/doi/10.1021/jacs.

  24. Joseph Tuccinardi and John Wood from Baylor University (#USA), introduced a novel strategy to efficiently synthesize the core scaffold of aleutianamine. Their study involved a vinylogous Mukaiyama-Michael reaction cascade using two previously unknown coupling partners. Published in

    me.organicchemistry.eu/post/al

  25. Joseph Tuccinardi and John Wood from Baylor University (#USA), introduced a novel strategy to efficiently synthesize the core scaffold of aleutianamine. Their study involved a vinylogous Mukaiyama-Michael reaction cascade using two previously unknown coupling partners. Published in #JACS

    me.organicchemistry.eu/post/al

    #orgchem #chemistry #totalsynthesis #science

  26. Joseph Tuccinardi and John Wood from Baylor University (#USA), introduced a novel strategy to efficiently synthesize the core scaffold of aleutianamine. Their study involved a vinylogous Mukaiyama-Michael reaction cascade using two previously unknown coupling partners. Published in #JACS

    me.organicchemistry.eu/post/al

    #orgchem #chemistry #totalsynthesis #science

  27. Joseph Tuccinardi and John Wood from Baylor University (#USA), introduced a novel strategy to efficiently synthesize the core scaffold of aleutianamine. Their study involved a vinylogous Mukaiyama-Michael reaction cascade using two previously unknown coupling partners. Published in #JACS

    me.organicchemistry.eu/post/al

    #orgchem #chemistry #totalsynthesis #science

  28. Joseph Tuccinardi and John Wood from Baylor University (#USA), introduced a novel strategy to efficiently synthesize the core scaffold of aleutianamine. Their study involved a vinylogous Mukaiyama-Michael reaction cascade using two previously unknown coupling partners. Published in #JACS

    me.organicchemistry.eu/post/al

    #orgchem #chemistry #totalsynthesis #science

  29. Computer-aided synthesis: R. Shenvi and C. Li published in the total synthesis of 25 picrotoxanes. Their 1,5-HAT key reaction was challenged by β-scission, therefore DFT based calculations helped to design usable intermediates.

    Read more on my page: me.organicchemistry.eu/post/pi

  30. Computer-aided synthesis: R. Shenvi and C. Li published in #Nature the total synthesis of 25 picrotoxanes. Their 1,5-HAT key reaction was challenged by β-scission, therefore DFT based calculations helped to design usable intermediates.

    Read more on my page: me.organicchemistry.eu/post/pi

    #totalsynthesis #chemistry #science

  31. Computer-aided synthesis: R. Shenvi and C. Li published in #Nature the total synthesis of 25 picrotoxanes. Their 1,5-HAT key reaction was challenged by β-scission, therefore DFT based calculations helped to design usable intermediates.

    Read more on my page: me.organicchemistry.eu/post/pi

    #totalsynthesis #chemistry #science

  32. Computer-aided synthesis: R. Shenvi and C. Li published in #Nature the total synthesis of 25 picrotoxanes. Their 1,5-HAT key reaction was challenged by β-scission, therefore DFT based calculations helped to design usable intermediates.

    Read more on my page: me.organicchemistry.eu/post/pi

    #totalsynthesis #chemistry #science

  33. Computer-aided synthesis: R. Shenvi and C. Li published in #Nature the total synthesis of 25 picrotoxanes. Their 1,5-HAT key reaction was challenged by β-scission, therefore DFT based calculations helped to design usable intermediates.

    Read more on my page: me.organicchemistry.eu/post/pi

    #totalsynthesis #chemistry #science

  34. Another total synthesis in the spotlight: Already early this year Mingji Dai and his research team described the total synthesis of heilonine in (doi: 10.1021/jacs.3c13492). This synthesis is short and elegant, using multiple C-H functionalisations and a Nazarov cyclisation for their key step.

    Read more: organicchemistry.eu/books/tota

  35. Another total synthesis in the spotlight: Already early this year Mingji Dai and his research team described the total synthesis of heilonine in #JACS (doi: 10.1021/jacs.3c13492). This synthesis is short and elegant, using multiple C-H functionalisations and a Nazarov cyclisation for their key step.

    Read more: organicchemistry.eu/books/tota

    #chemistry #science #totalsynthesis

  36. Another total synthesis in the spotlight: Already early this year Mingji Dai and his research team described the total synthesis of heilonine in #JACS (doi: 10.1021/jacs.3c13492). This synthesis is short and elegant, using multiple C-H functionalisations and a Nazarov cyclisation for their key step.

    Read more: organicchemistry.eu/books/tota

    #chemistry #science #totalsynthesis

  37. Another total synthesis in the spotlight: Already early this year Mingji Dai and his research team described the total synthesis of heilonine in #JACS (doi: 10.1021/jacs.3c13492). This synthesis is short and elegant, using multiple C-H functionalisations and a Nazarov cyclisation for their key step.

    Read more: organicchemistry.eu/books/tota

    #chemistry #science #totalsynthesis

  38. Another total synthesis in the spotlight: Already early this year Mingji Dai and his research team described the total synthesis of heilonine in #JACS (doi: 10.1021/jacs.3c13492). This synthesis is short and elegant, using multiple C-H functionalisations and a Nazarov cyclisation for their key step.

    Read more: organicchemistry.eu/books/tota

    #chemistry #science #totalsynthesis

  39. Total Synthesis of Pleurotin (JACS Au, Y. Q. Long 2024)

    Pleurotin is a benzoquinone meroterpenoid that was first isolated in the late 1940s. Since that time, several total syntheses of this compound have been reported. Recently, Ya-Qiu Long and his team from Soochow University (#China) published a novel synthetic route in the journal JACS Au.

    Read more here: organicchemistry.eu/books/tota

  40. Total Synthesis of Pleurotin (JACS Au, Y. Q. Long 2024)

    Pleurotin is a benzoquinone meroterpenoid that was first isolated in the late 1940s. Since that time, several total syntheses of this compound have been reported. Recently, Ya-Qiu Long and his team from Soochow University (#China) published a novel synthetic route in the journal JACS Au.

    Read more here: organicchemistry.eu/books/tota

    #chemistry #totalsynthesis #reasearch #science

  41. Total Synthesis of Pleurotin (JACS Au, Y. Q. Long 2024)

    Pleurotin is a benzoquinone meroterpenoid that was first isolated in the late 1940s. Since that time, several total syntheses of this compound have been reported. Recently, Ya-Qiu Long and his team from Soochow University (#China) published a novel synthetic route in the journal JACS Au.

    Read more here: organicchemistry.eu/books/tota

    #chemistry #totalsynthesis #reasearch #science

  42. Total Synthesis of Pleurotin (JACS Au, Y. Q. Long 2024)

    Pleurotin is a benzoquinone meroterpenoid that was first isolated in the late 1940s. Since that time, several total syntheses of this compound have been reported. Recently, Ya-Qiu Long and his team from Soochow University (#China) published a novel synthetic route in the journal JACS Au.

    Read more here: organicchemistry.eu/books/tota

    #chemistry #totalsynthesis #reasearch #science

  43. Total Synthesis of Pleurotin (JACS Au, Y. Q. Long 2024)

    Pleurotin is a benzoquinone meroterpenoid that was first isolated in the late 1940s. Since that time, several total syntheses of this compound have been reported. Recently, Ya-Qiu Long and his team from Soochow University (#China) published a novel synthetic route in the journal JACS Au.

    Read more here: organicchemistry.eu/books/tota

    #chemistry #totalsynthesis #reasearch #science

  44. First Total Synthesis of Garajonone

    Two-stage synthetic strategy provides access to ryanodane diterpenes, a type of structurally complex natural product

    chemistryviews.org/first-total