-
⚗️ For everyone interested in the synthesis of #antiviral #drugs:
I collected 7 synthesis routes for #entecavir, a marketed #HBV antiviral. At first sight, this carbocyclic nucleoside analogue looks quite simple, however, its synthesis requires a multi-step total synthesis.
Check the article for further information and share it with your audience:
https://www.organicchemistry.eu/books/nucleoside-analogues/page/synthesis-strategies-for-entecavir