Making biomolecules glow: new dye solves problem
Organic molecules – such as sugars, proteins and lipids - are the building blocks of life. To study them via a microscope, special dyes are used to make them glow. Researchers at our Uni have now developed a new method to do this better. Unlike conventional approaches, the luminescent dye is not added to the sample as a ready-made product. Instead, it only begins to glow as it binds to the target molecule. This solves the old problem of pre-made dyes remaining in the sample even when they are not bound to the target molecule, which interferes with imaging: https://www.uni-goettingen.de/en/3240.html?id=8179
Research in #AngewandteChemie International edition: https://doi.org/10.1002/anie.6231674