#polyketide — Public Fediverse posts

Nowadays, a lot of total #synthesis projects include terpenes with a C-H functionalization strategy.

In contrast, Alois Fürstner and co-workers (MPG Mülheim) recently presented their synthesis of prorocentin, a complex #polyketide, in #JACS featuring up-to-date transformations and beautifully designed synthetic routes. I added this synthesis now to my collection, have a look 👇

https://www.organicchemistry.eu/books/total-syntheses-of-natural-products/page/first-total-synthesis-and-structural-revision-of-prorocentin-a-furstner-2023

#chemistry @chemistry

#Yellow #pigment keeps #SocialAmoebae together https://www.eurekalert.org/news-releases/968378 #Protists #SlimeMolds #Polyketides #Pigments

Paper: Yellow #polyketide pigment suppresses premature #hatching in social amoeba https://www.pnas.org/doi/10.1073/pnas.2116122119

The #multicellular stage of the #amoeba #Dicyostelium discoideum is partially regulated by an intensely yellow natural substance. The newly identified natural product of the polyketide family prevents the #amoebae #spores from hatching too early.