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#jacs — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #jacs, aggregated by home.social.

  1. Fantastic paper from Brooks Able at Berkeley using an organic catalyst to achieve high molecular weight for poly(THF) via cationic ring-opening polymerization. The low ceiling temperatures of these polymers make them attractive targets for reversible polymerizations, but it has previously been really hard to get to the molecular weights required for good mechanical properties. #chemistry #polymers #JACS pubs.acs.org/doi/10.1021/jacs.

  2. Fantastic paper from Brooks Able at Berkeley using an organic catalyst to achieve high molecular weight for poly(THF) via cationic ring-opening polymerization. The low ceiling temperatures of these polymers make them attractive targets for reversible polymerizations, but it has previously been really hard to get to the molecular weights required for good mechanical properties. #chemistry #polymers #JACS pubs.acs.org/doi/10.1021/jacs.

  3. Efficient Synthesis of ProTide antivirals: A team from from #Fudan University and #Shanghai Jiao Tong University reporting a copper-catalyzed method for synthesizing chiral phosphates in #JACS.

    This research represents a new tool for the synthesis of ProTide nucleoside analogues, providing an efficient route that can enhance the development of antiviral drugs in future studies.

    doi.org/10.1021/jacs.4c12920

    #MedChem #Antivirals #Research #Science #Chemistry

  4. Efficient Synthesis of ProTide antivirals: A team from from #Fudan University and #Shanghai Jiao Tong University reporting a copper-catalyzed method for synthesizing chiral phosphates in #JACS.

    This research represents a new tool for the synthesis of ProTide nucleoside analogues, providing an efficient route that can enhance the development of antiviral drugs in future studies.

    doi.org/10.1021/jacs.4c12920

    #MedChem #Antivirals #Research #Science #Chemistry

  5. Nostalgic toot warning! ⚠️

    We often celebrate birthdays 🎂 of #scientists whose research was impactful on our lives.

    But is marking the publication anniversary of research that was a #TurningPoint in our #science career a thing? 🤔

    If so, a 40th anniversary toot to a #JACS paper that will remain relevant as long as #chemistry students learn about Ron Gillespie’s #VSEPR model and #chemists use it to intuitively understand the shapes of molecules.
    pubs.acs.org/doi/abs/10.1021/j

  6. Nostalgic toot warning! ⚠️

    We often celebrate birthdays 🎂 of #scientists whose research was impactful on our lives.

    But is marking the publication anniversary of research that was a #TurningPoint in our #science career a thing? 🤔

    If so, a 40th anniversary toot to a #JACS paper that will remain relevant as long as #chemistry students learn about Ron Gillespie’s #VSEPR model and #chemists use it to intuitively understand the shapes of molecules.
    pubs.acs.org/doi/abs/10.1021/j

  7. Stephadiamine is a popular synthetic challenge which resulted in many total syntheses before. Now, Jieping Zhu (EPFL, Lausanne) and co-workers were able to report in #JACS a new route to the #alkaloid with a hasubanan core structure featuring a diastereoselective intramolecular dipolar cycloaddition.

    doi.org/10.1021/jacs.3c00884

    #chemistry #totalsynthesis @chemistry

  8. Stephadiamine is a popular synthetic challenge which resulted in many total syntheses before. Now, Jieping Zhu (EPFL, Lausanne) and co-workers were able to report in #JACS a new route to the #alkaloid with a hasubanan core structure featuring a diastereoselective intramolecular dipolar cycloaddition.

    doi.org/10.1021/jacs.3c00884

    #chemistry #totalsynthesis @chemistry

  9. Total synthesis of Alterbrassicene C:

    John L Wood (Baylor University, #US) et al reported the first total synthesis of the terpenoid in #JACS (10.1021/jacs.2c12275). I feautered this #synthesis because I like these kinds of oxa-Michael cascade reactions. Since many terpenoid syntheses these days often involve CH activation strategies, it's refreshing to see other approaches in action.

    Read more: organicchemistry.eu/books/tota

    @chemistry #chemistry #totalsynthesis #terpene

  10. Total synthesis of Alterbrassicene C:

    John L Wood (Baylor University, #US) et al reported the first total synthesis of the terpenoid in #JACS (10.1021/jacs.2c12275). I feautered this #synthesis because I like these kinds of oxa-Michael cascade reactions. Since many terpenoid syntheses these days often involve CH activation strategies, it's refreshing to see other approaches in action.

    Read more: organicchemistry.eu/books/tota

    @chemistry #chemistry #totalsynthesis #terpene