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  1. Same purine skeleton as caffeine and theobromine, a different arrangement of methyls — a small structural edit with an entirely medical life. The structural formula is drawn front and centre, named beneath.

    #TeaChemistry #OrganicChemistry #scienceart #sciart #fediscience

  2. Theobromine is caffeine's gentler cousin — the main stimulant in cacao, its name literally the Greek for 'food of the gods'. Same xanthine core as caffeine, one fewer methyl group, and a milder, longer, warmer lift instead of a sharp jolt.

    #ChocolateChemistry #CocoaMolecule #OrganicChemistry #scienceart #sciart #fediscience

  3. Caffeine — 1,3,7-trimethylxanthine — is the most widely used psychoactive molecule on earth. It works by blocking adenosine, the messenger that builds up through the day and makes you drowsy; caffeine slips into the same receptors and holds the tiredness off.

    #OrganicChemistry #CaffeineMolecule #scienceart #sciart #fediscience

  4. Quimica Orgánica by V. M. Potapov; S. N. Tatarinchik

    La química orgánica atraviesa un período de notable desarrollo caracterizado por el descubrimiento de nuevas sustancias con propiedades excepcionales y la creación de compuestos innovadores de aplicación práctica en diversas áreas. Este progreso se apoya en el uso de métodos modernos de investigación fundamentados en la física y en una profundización de las nociones teóricas. Sin embargo, esto plantea retos educativos, ya que es necesario condensar una gran cantidad de material en los planes de estudio. Los autores abogan por priorizar las leyes generales de la química orgánica, dejando en segundo plano el contenido puramente descriptivo, y basan su enfoque en la teoría de la estructura química de Bútlerov, complementada con una mejor comprensión de los enlaces químicos y las reacciones orgánicas. Este enfoque permite clasificar las reacciones de manera sistemática y facilitar su aprendizaje.

    El libro sigue una clasificación basada en los grupos funcionales, que determinan el comportamiento químico de los compuestos orgánicos. Se abordan primero los hidrocarburos y luego sus derivados, incluyendo halogenados e hidroxílicos, destacando aquellos compuestos de relevancia práctica en la industria, agricultura y medicina. Para esta nueva edición, los autores han incorporado recomendaciones de instituciones académicas como las escuelas politécnicas de Moscú y Leningrado, ajustando el contenido al programa aprobado en 1974 para especialidades como química analítica y química de explotaciones petrolíferas. Finalmente, los autores invitan a los lectores a proporcionar observaciones críticas para mejorar la obra en futuras ediciones.

     

    Traducido del ruso por Neiml Sosa

    Todos los créditos a los cargadores originales.

    Nota: La calidad del escaneo es promedio

    You can get the book here and here

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    #chemicalReactions #OrganicChemistry #sovietLiterature
  5. What if a chemistry concept taught for nearly 100 years has been explained incorrectly?

    Researchers say the inductive effect in neutral molecules may not gradually extend across three or four chemical bonds as many textbooks teach. Instead, their findings suggest its influence may stop after just one bond. 😮

    Modern tools are giving scientists new ways to challenge ideas that have been accepted for generations.

    Read more: sciencedaily.com/releases/2026

    #Chemistry #Science #OrganicChemistry #Education #Research

  6. RhoBAST is a small, specialized RNA molecule (a fluorescent light-up aptamer) that binds to and activates specific fluorescent dyes, allowing researchers to track individual RNA molecules inside living cells with high resolution.
    #Biochemistry #MolecularBiology #OrganicChemistry #Biophysics #sflorg
    sflorg.com/2026/09/bchm0913260

  7. Laboratory Manual Of Organic Synthesis by M. N. Khramkina

    This book explains the modern theoretical concepts of organic chemistry to the extent needed for carrying out synthesis. A more detailed exposition of theoretical aspects, especially those involving the reaction mechanisms, is given in textbooks of organic chemistry.

    This textbook presents a large number of syntheses. The greatest attention is devoted to laboratory operations which are of practical and methodological importance. If need be, a laboratory operation in a given subject can be replaced by a similar one in the students’ future speciality. In addition, when there is a large number of syntheses, the instructor can select those needed for review problems to see how well the students have learned their material.

    Certain guides to organic synthesis were used when the textbook was being written.

    This edition of the textbook has new material on the mechanism of individual reactions and a chapter on the identification of organic compounds.

    Translated from the Russian by Nicholas Bobrov

    Credits to the original uploaders, this is a cleaned optimised scan.

    You can get the book here and here

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    CONTENTS
    Preface
    Part I — METHODS USED IN ORGANIC SYNTHESIS
    Chapter 1 — WORK AND SAFETY RULES
    1.1. Principal Laboratory Operations
    Assembly
    Cleaning and Drying Laboratory Equipment
    Literature, Notebooks and Reports
    1.2. Safety Rules in the Organic Synthesis Laboratory
    Precautions and First Aid in Case of Accidents
    Work with Poisons and Caustics
    Work with Highly Flammable Substances and Explosives
    Rules of Handling Glassware
    First Aid in Case of Burns, Poisonings and Other Accidents
    Local Fires and Burning Laboratory Equipment
    Chapter 2 — PRINCIPAL LABORATORY OPERATIONS
    2.1. Heating
    2.2. Cooling
    2.3. Measuring and Controlling the Temperature
    2.4. Grinding and Stirring
    2.5. Dissolution and Properties of Some Organic Solvents
    Ethyl Alcohol
    Methyl Alcohol
    Ether
    Petroleum Ether
    Acetone
    2.6. Drying and Principal Drying Agents
    Drying Gases
    Drying Organic Liquids
    Drying Solids
    Principal Drying Agents
    2.7. Filtration
    Filtration at Atmospheric Pressure
    Suction Filtration
    Chapter 3 — METHODS OF PURIFYING ORGANIC SUBSTANCES
    3.1. Crystallisation
    Solvent Selection
    Recrystallisation Procedure
    Formation of Crystals
    3.2. Sublimation
    3.3. Extraction
    3.4. Distillation
    Simple Distillation at Atmospheric Pressure
    Steam Distillation
    Vacuum Distillation (at Reduced Pressure)
    Fractional Distillation
    Rectification
    3.5. Chromatography
    Adsorption Chromatography (Column Chromatography)
    Partition Chromatography
    Paper Chromatography
    Ion Exchange Chromatography
    Chapter 4 — DETERMINATION OF THE PRINCIPAL CONSTANTS OF ORGANIC COMPOUNDS
    4.1. Melting Point
    4.2. Boiling Point
    4.3. Specific Gravity
    4.4. Refractive Index
    4.5. Molecular Weight
    Chapter 5 — WORK WITH COMPRESSED AND LIQUEFIED GASES
    5.1. Gas Cylinders and How to Use Them
    5.2. Dosing Gases
    5.3. Purification of Gases and Their Introduction into an Apparatus
    5.4. Safety Rules in Handling Gas Cylinders
    Chapter 6 — QUANTITATIVE ELEMENTAL ANALYSIS OF ORGANIC SUBSTANCES
    6.1. Semimicrodetermination of Carbon and Hydrogen
    Assembly
    Analysis
    6.2. Semimicrodetermination of Nitrogen (According to Dumas)
    Assembly
    Analysis
    6.3. Microdetermination of Carbon and Hydrogen
    Assembly
    Analysis
    Part II — SYNTHESES OF ORGANIC SUBSTANCES
    Chapter 7 — HALOGENATION REACTIONS
    7.1. Replacement of the Hydroxyl Group of Alcohols by a Halogen
    7.2. Replacement of the Hydroxyl Group of Acids by a Halogen
    7.3. Halogen Addition to a Multiple Bond
    7.4. Direct Replacement of Hydrogen by a Halogen
    7.5. Syntheses
    Ethyl Bromide
    Acetylene and Ethyl Bromide
    Ethyl Iodide
    Butyl Bromide
    Acetyl Chloride
    Benzoyl Chloride
    1,2-Dibromoethane
    Bromobenzene
    α-Bromonaphthalene
    p-Bromoanisole
    Chapter 8 — ALKYLATION REACTIONS
    8.1. Alkylation of Aromatic Compounds by Alcohols in the Presence of Sulphuric Acid
    8.2. Preparation of Ethers
    8.3. Syntheses
    sec-Butylbenzene
    Dibutyl Ether
    Isoamyl Ether
    Diphenyl Ether
    Phenetole
    β-Naphthyl Ethyl Ether (Nerolin, Bromelia)
    Anisole
    Chapter 9 — ACYLATION REACTIONS
    9.1. Acylation of Alcohols and Amines by Carboxylic Acids
    9.2. Acylation of Alcohols, Phenols and Amines by Acyl Chlorides
    9.3. Acylation of Amines by Acid Anhydrides
    9.4. Syntheses
    Ethyl Acetate
    Isoamyl Acetate
    Ethyl Chloroacetate
    Diethyl Oxalate (Oxalic Ester)
    Ethyl Benzoate
    Benzanilide
    Aspirin (Acetylsalicylic Acid)
    β-Naphthyl Acetate
    Acetanilide
    Chapter 10 — FRIEDEL-CRAFTS REACTIONS
    10.1. Alkylation of Aromatic Compounds
    10.2. Acylation of Aromatic Compounds
    10.3. Syntheses
    Isopropylbenzene
    Diphenylmethane
    Acetophenone
    Benzophenone
    Chapter 11 — OXIDATION REACTIONS
    11.1. Oxidation at the Double Bond
    11.2. Oxidation of Primary and Secondary Alcohols to Aldehydes or Ketones
    11.3. Oxidation of Aldehydes and Ketones to Acids
    11.4. Oxidation of Methyl and Methylene Groups
    11.5. Preparation of Quinones by Oxidation
    11.6. Syntheses
    Acetaldehyde
    Propionaldehyde
    Isovaleraldehyde
    Benzophenone
    Isobutyric Acid
    Valeric Acid
    Benzoic Acid
    Benzoquinone
    Anthraquinone
    Chapter 12 — NITRATION REACTIONS
    12.1. Nitration of Hydrocarbons of the Fatty Series
    12.2. Nitration of Hydrocarbons of the Aromatic Series
    12.3. Syntheses
    Nitromethane
    Nitrobenzene
    o-,p-Nitrotoluene
    o-,p-Nitrophenol
    α-Nitronaphthalene
    Chapter 13 — AMINATION REACTIONS
    13.1. Preparation of Amines of the Fatty Series
    13.2. Preparation of Amines of the Aromatic Series
    13.3. Syntheses
    Methylamine
    Aniline
    o-,p-Toluidine
    α-Naphthylamine
    Preparation of α-Naphthylamine Hydrochloride
    Chapter 14 — SULPHONATION REACTIONS
    14.1. Sulphonation of Aromatic Compounds
    14.2. Syntheses
    β-Naphthalenesulphonic Acid (Sodium Salt)
    Benzenesulphonic Acid (Sodium Salt)
    p-Toluenesulphonic Acid
    Sulphanilic Acid
    Chapter 15 — DIAZOTIZATION AND AZO COUPLING REACTIONS
    15.1. Diazonium Salt Reactions with Loss of Nitrogen
    15.2. Diazonium Salt Reactions without Loss of Nitrogen
    15.3. Syntheses
    Phenol
    Iodobenzene
    Helianthin
    β-Naphthol Orange
    Chapter 16 — GRIGNARD REACTIONS
    16.1. Preparation of Hydrocarbons
    Quantitative Determination of Active Hydrogen by the Chugaev-Tserevitinov Method
    16.2. Preparation of Carboxylic Acids
    16.3. Preparation of Alcohols
    16.4. Syntheses
    Phenylacetic Acid
    Triphenylcarbinol
    Diphenylcarbinol (Benzhydrol)
    Chapter 17 — CANNIZZARO REACTIONS
    17.1. Synthesis of Benzoic Acid and Benzyl Alcohol
    Chapter 18 — CLAISEN REACTIONS
    18.1. Syntheses
    Ethyl Acetoacetate
    Benzoylacetone
    Chapter 19 — POLYMERIZATION AND POLYCONDENSATION REACTIONS
    19.1. Polymerization
    19.2. Polycondensation (Condensation Polymerization)
    19.3. Syntheses
    Paraldehyde
    Polystyrene
    Polymethyl Methacrylate
    Copolymer of Styrene with Methyl Methacrylate
    Methyl Methacrylate (from Methyl Methacrylate)
    Glyptal Resin
    Phenol-Formaldehyde Resin
    Chapter 20 — IDENTIFICATION
    20.1. Preliminary Tests
    20.2. Qualitative Reactions
    20.3. Preparation of Derivatives
    RECOMMENDED LITERATURE
    SUPPLEMENTS
    Drying Agents for Organic Compounds
    Steam Pressure at Different Temperatures
    Pressure of Liquefied Gases in Cylinders
    Colour Code of Compressed Gas Cylinders
    Density of Sulphuric Acid Solutions (20°C)
    Density of Hydrochloric Acid Solutions (20°C)
    Density of Nitric Acid Solutions (20°C)
    Density of Sodium Hydroxide Solutions (20°C)
    Density of Potassium Hydroxide Solutions (20°C)
    Physical Properties of Alcohols and Their Derivatives
    Physical Properties of Phenols and Their Derivatives
    Physical Properties of Aldehydes and Their Derivatives
    Physical Properties of Ketones and Their Derivatives
    Physical Properties of Carboxylic Acids and Their Derivatives
    Physical Properties of Primary and Secondary Amines and Their Derivatives (Acetamides)
    Physical Properties of Acid Halides and Their Derivatives (Anilides)

    #chemicalExperiments #chemicalLaboratory #OrganicChemistry #sovietLiterature #textbook
  8. A bit late to the party, but still interesting. In 2023 Yong Qin and co-workers from Sichuan #University in #China published in #JACS the first #totalsynthesis of the terpene garryine.

    The total synthesis heavily relies on [Pd] catalyzed cross couplings including a enantioselective variant of an intramolecular Heck coupling.

    The draft has been added to my page some years ago, but only finished today.

    organicchemistry.eu/books/tota

    #chemistry #science #organicchemistry

  9. A protein–foldamer supramolecular synthon for self-assembled hybrid architectures

    Regan, L. & DeGrado, W. F. Characterization of a helical protein designed from first principles. Science 241, 976–978…
    #NewsBeep #News #Science #AnalyticalChemistry #biochemistry #Chemistry/FoodScience #GB #general #InorganicChemistry #OrganicChemistry #PhysicalChemistry #proteins #Self-assembly #UK #UnitedKingdom
    newsbeep.com/uk/741645/

  10. Did you know that the Beilstein-Institut turns 75 this year? 🎉
    Founded as a non-profit foundation in 1951, we've grown into a driving force behind Diamond Open Access publishing, chemical data standards, and international scientific exchange.

    We're touched by all the warm wishes rolling in from our vibrant global community.
    👉 Read more: beilstein-institut.de/en/about

    #Beilstein75 #chemistry #DiamondOpenAccess #OrganicChemistry #nanotechnology #BJOC #BJNANO

  11. Two molecules, the same atoms bonded the same way — and yet one smells of oranges and the other of lemons. Limonene is a cyclic monoterpene pressed from citrus peel, and it is chiral: it exists as two non-superimposable mirror images.

    #LimoneneMolecule #ChiralityArt #OrganicChemistry #chemistry #molecularart #scienceart #sciart #fediscience

  12. Deciphering the infrared spectrum of the hydrated proton using full-dimensional quantum dynamics

    Li, S. et al. Attosecond-pump attosecond-probe X-ray spectroscopy of liquid water. Science 383, 1118–1122 (2024). Article  CAS  PubMed …
    #NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Physics #AnalyticalChemistry #Biochemistry #Chemistry/FoodScience #general #Inorganicchemistry #OrganicChemistry #PhysicalChemistry #Science #Theoreticalchemistry
    newsbeep.com/us/790137/

  13. Space is sweet.
    Not saying that hyperbolically, we now have indications for the presence of sugar in interstellar medium.

    Link: arxiv.org/abs/2606.03313

    #Space #OrganicChemistry

  14. 💬 Behind the Science Interview with Navadheer Yalamanchili (École Polytechnique Fédérale de Lausanne (EPFL), Switzerland)

    He discusses how the self-assembly of simple catalysts into a chiral environment enables efficient deracemization of racemic mixtures, avoiding the need to synthesize complex chiral catalysts

    chemistryviews.org/teaching-a-

    #EPFL #catalysis #organicchemistry

  15. Thank you all, you lovely people who responded to my recent post about named reactions. Too many to name right now but you know who you are.

    The reason I asked is that we're compiling some custom libraries for @chem4word . Named reactions will be one of them. We intend to make these available at a competitive price: Chem4Word has been and will continue to be free.🙂

    Here's a taster of what's coming up!

    #chemistry #organicchemistry

  16. バニラアイスに石油が入ってるって本当? #organicchemistry #reactionmechamism #有機化学 #化学 #sho... youtube.com/shorts/HcCe_Pb9t3M

    バニリン(バニラ香料)は石油を原料に合成するとアホ安く作れる、という大前提があるにはあると思いつつ

  17. Textbooks May Need Rewriting After Researchers Debunk a Core Chemistry Concept

    A new study suggests that a long-standing concept used to explain how electrons behave in molecules may not…
    #NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Science #Electrons #MolecularChemistry #NewcastleUniversity #OrganicChemistry
    newsbeep.com/us/756218/

  18. #Chemistry friends:
    I am after a comprehensive, preferably exhaustive list of named organic reactions. Doesn't have to have accompanying reaction schemes. Just a list of the names will do.

    Thanks
    #chemistry #organicchemistry

  19. Archaeologists May Have Been Wrong About Olive Oil for Decades, New Study Finds

    A new study challenges decades of archaeological interpretations by showing that Mediterranean soils can alter the chemical traces of anci…
    #dining #cooking #diet #food #MediterraneanOliveOil #OliveOil #Archaeology #CornellUniversity #foodscience #Mediterranean #Olive #organicchemistry #Prehistory
    diningandcooking.com/2721322/a

  20. 🎁 Happy 80th birthday to K. C. Nicolaou—master of “the art of total synthesis”, whose landmark syntheses of Calicheamicin, Taxol, Brevetoxin B, Epothilone, and Vancomycin helped shape modern organic chemistry. #TotalSynthesis #OrganicChemistry

  21. Alkyl Swap is a novel chemical methodology that allows scientists to directly edit complex molecules by replacing specific methyl groups, bypassing the need to reconstruct the entire molecule from scratch.
    #OrganicChemistry #SyntheticChemistry #Pharmacology #sflorg
    sflorg.com/2026/06/chm06152601

  22. A novel chemical method for visualizing biomolecules under a microscope by building a fluorescent label directly where it is needed on the target, rather than attaching a pre-made dye.
    #OrganicChemistry #BiomolecularChemistry #Biochemistry #CellBiology #sflorg
    sflorg.com/2026/05/chm05212601

  23. Light-Driven Method Produces Strained Housane Molecules for Drug Development

    📰 Original title: Scientists use light to create tiny molecules that could transform medicine

    🤖 IA: It's not clickbait ✅
    👥 Users: It's not clickbait ✅

    View full AI summary: en.killbait.com/light-driven-m

    #science #photocatalysis #organicchemistry #molecules

  24. Light-Driven Method Produces Strained Housane Molecules for Drug Development

    📰 Original title: Scientists use light to create tiny molecules that could transform medicine

    🤖 IA: It's not clickbait ✅
    👥 Users: It's not clickbait ✅

    View full AI summary: en.killbait.com/light-driven-m

    #science #photocatalysis #organicchemistry #molecules

  25. Long-Held Chemistry Tenet Questioned

    A new study from the University of Newcastle challenges long-held rules in organic chemistry. This could change how science is taught.

    #OrganicChemistry, #ScienceEducation, #ChemistryResearch, #UniversityNewcastle, #MolecularBehavior

    newsletter.tf/organic-chemistr

  26. A novel synthesis method that utilizes "cation sampling" to guide positive charges along molecular chains, allowing for the precise modification of previously hard-to-reach carbon-hydrogen (C–H) bonds.
    #OrganicChemistry #SyntheticChemistry #Chemistry #sflorg
    sflorg.com/2026/05/chm05192601

  27. Molecular emergence is the scientific phenomenon in which simple chemical building blocks combine to form complex systems with entirely new, unpredictable properties that cannot be derived from their individual components. It provides a theoretical framework for understanding the profound transition from non-living matter to self-replicating, living systems.
    #OrganicChemistry #ChemicalBiology #EvolutionaryBiology #sflorg
    sflorg.com/2026/05/chm05052601

  28. Happy 15th Anniversary to our outstanding Editor-in-Chief, Professor Peter Seeberger, Max Planck Institute of Colloids and Interfaces, at at the Beilstein Journal of Organic Chemistry! 🎉

    🔗 tinyurl.com/4bafszm6

    Since 2011, he has been a cornerstone of our success, empowering the #OrganicChemistry community to share high-quality research – FREE for authors, readers, universities and funders.

    Thank you, Professor Seeberger, for your support and wise counsel over the years!
    #BJOC 💎🔓

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