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  1. Contact probability, not structure: how AlphaFold3 rewrote the rules of base editor design

    Share if you found this interesting.

    1ban.news/contactseek-alphafol

    #1ban #contactseek #alphafold3 #base #editing #science

  2. Contact probability, not structure: how AlphaFold3 rewrote the rules of base editor design

    Share if you found this interesting.

    1ban.news/contactseek-alphafol

    #1ban #contactseek #alphafold3 #base #editing #science

  3. Contact probability, not structure: how AlphaFold3 rewrote the rules of base editor design

    Share if you found this interesting.

    1ban.news/contactseek-alphafol

    #1ban #contactseek #alphafold3 #base #editing #science

  4. Contact probability, not structure: how AlphaFold3 rewrote the rules of base editor design

    Share if you found this interesting.

    1ban.news/contactseek-alphafol

    #1ban #contactseek #alphafold3 #base #editing #science

  5. Contact probability, not structure: how AlphaFold3 rewrote the rules of base editor design

    Share if you found this interesting.

    1ban.news/contactseek-alphafol

    #1ban #contactseek #alphafold3 #base #editing #science

  6. Reprograman Nicotiana benthamiana con genes de varios reinos para producir 5 psicodélicos (DMT, psilocibina…) en una semana; AlphaFold3 elevó 5‑MeO‑DMT x40. aidoo.news/noticia/xZdVG6

    #ScienceAdvances #AlphaFold3 #InteligenciaArtificial #SaludMental #Investigacion

  7. 💡 AI can predict protein structures — but can it predict how they behave?

    🔗 AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis?. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.10

    📚 CSBJ: csbj.org/

    #AlphaFold3 #ProteinDesign #MolecularModeling #ComputationalBiology #StructuralBiology #Thermodynamics #ProteinProteinInteractions #Bioinformatics

  8. 💡 AI can predict protein structures — but can it predict how they behave?

    🔗 AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis?. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.10

    📚 CSBJ: csbj.org/

    #AlphaFold3 #ProteinDesign #MolecularModeling #ComputationalBiology #StructuralBiology #Thermodynamics #ProteinProteinInteractions #Bioinformatics

  9. 💡 AI can predict protein structures — but can it predict how they behave?

    🔗 AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis?. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.10

    📚 CSBJ: csbj.org/

    #AlphaFold3 #ProteinDesign #MolecularModeling #ComputationalBiology #StructuralBiology #Thermodynamics #ProteinProteinInteractions #Bioinformatics

  10. 💡 AI can predict protein structures — but can it predict how they behave?

    🔗 AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis?. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.10

    📚 CSBJ: csbj.org/

    #AlphaFold3 #ProteinDesign #MolecularModeling #ComputationalBiology #StructuralBiology #Thermodynamics #ProteinProteinInteractions #Bioinformatics

  11. 💡 AI can predict protein structures — but can it predict how they behave?

    🔗 AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis?. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.10

    📚 CSBJ: csbj.org/

    #AlphaFold3 #ProteinDesign #MolecularModeling #ComputationalBiology #StructuralBiology #Thermodynamics #ProteinProteinInteractions #Bioinformatics

  12. 🚀 GenAI isn’t science fiction anymore. From GPT-4o aiding the blind to AlphaFold 3 cutting drug discovery timelines by 50%, the future is already here.

    👁️ Explore how 4 GenAI breakthroughs are transforming vision, video, medicine, and work—plus what comes next.

    #GenAI #GPT4o #Sora #AlphaFold3 #AIethics #AgenticAI #AIin2025

    🔗
    medium.com/@rogt.x1997/4-genai

  13. 🚀 GenAI isn’t science fiction anymore. From GPT-4o aiding the blind to AlphaFold 3 cutting drug discovery timelines by 50%, the future is already here.

    👁️ Explore how 4 GenAI breakthroughs are transforming vision, video, medicine, and work—plus what comes next.

    #GenAI #GPT4o #Sora #AlphaFold3 #AIethics #AgenticAI #AIin2025

    🔗
    medium.com/@rogt.x1997/4-genai

  14. 🚀 GenAI isn’t science fiction anymore. From GPT-4o aiding the blind to AlphaFold 3 cutting drug discovery timelines by 50%, the future is already here.

    👁️ Explore how 4 GenAI breakthroughs are transforming vision, video, medicine, and work—plus what comes next.

    #GenAI #GPT4o #Sora #AlphaFold3 #AIethics #AgenticAI #AIin2025

    🔗
    medium.com/@rogt.x1997/4-genai

  15. 🚀 GenAI isn’t science fiction anymore. From GPT-4o aiding the blind to AlphaFold 3 cutting drug discovery timelines by 50%, the future is already here.

    👁️ Explore how 4 GenAI breakthroughs are transforming vision, video, medicine, and work—plus what comes next.

    #GenAI #GPT4o #Sora #AlphaFold3 #AIethics #AgenticAI #AIin2025

    🔗
    medium.com/@rogt.x1997/4-genai

  16. Protip: If you specify an AlphaFold 3 ligand by ccdCode, it has to have brackets around it. If it doesn't, each individual element of the string will be evaluated as a code which is probably not what you want.

    Wrong:

    "ccdCodes": "C2E"
    ValueError: Unknown residue type 2

    Right:
    "ccdCodes": ["C2E"]

    #AlphaFold3

  17. Protip: If you specify an AlphaFold 3 ligand by ccdCode, it has to have brackets around it. If it doesn't, each individual element of the string will be evaluated as a code which is probably not what you want.

    Wrong:

    "ccdCodes": "C2E"
    ValueError: Unknown residue type 2

    Right:
    "ccdCodes": ["C2E"]

    #AlphaFold3

  18. Protip: If you specify an AlphaFold 3 ligand by ccdCode, it has to have brackets around it. If it doesn't, each individual element of the string will be evaluated as a code which is probably not what you want.

    Wrong:

    "ccdCodes": "C2E"
    ValueError: Unknown residue type 2

    Right:
    "ccdCodes": ["C2E"]

    #AlphaFold3

  19. so now deepmind has gone and released alphafold3 code as well. must have been feeling the competition.

    source code here: github.com/google-deepmind/alp

    🧪🧬🖥️
    #alphafold3 #bioinformatics #ai #ml

  20. so now deepmind has gone and released alphafold3 code as well. must have been feeling the competition.

    source code here: github.com/google-deepmind/alp

    🧪🧬🖥️

  21. so now deepmind has gone and released alphafold3 code as well. must have been feeling the competition.

    source code here: github.com/google-deepmind/alp

    🧪🧬🖥️
    #alphafold3 #bioinformatics #ai #ml

  22. so now deepmind has gone and released alphafold3 code as well. must have been feeling the competition.

    source code here: github.com/google-deepmind/alp

    🧪🧬🖥️
    #alphafold3 #bioinformatics #ai #ml

  23. @xtaldave @graemewinter I was just preparing my "6 month are over"-Tweet to be released tomorrow and found this: github.com/google-deepmind/alp So google did hold their promise with 48h to spare 😅 It will take me time to implement it, but I cannot wait to see it for myself! #AlphaFold3

  24. @xtaldave @graemewinter I was just preparing my "6 month are over"-Tweet to be released tomorrow and found this: github.com/google-deepmind/alp So google did hold their promise with 48h to spare 😅 It will take me time to implement it, but I cannot wait to see it for myself! #AlphaFold3

  25. @xtaldave @graemewinter I was just preparing my "6 month are over"-Tweet to be released tomorrow and found this: github.com/google-deepmind/alp So google did hold their promise with 48h to spare 😅 It will take me time to implement it, but I cannot wait to see it for myself! #AlphaFold3

  26. @xtaldave @graemewinter I was just preparing my "6 month are over"-Tweet to be released tomorrow and found this: github.com/google-deepmind/alp So google did hold their promise with 48h to spare 😅 It will take me time to implement it, but I cannot wait to see it for myself! #AlphaFold3

  27. #DeepMind finally released the code of #AlphaFold3! But with very restrictive conditions to use the model weights... And anyway, I wonder which academic lab has the hardware to run it, beside David Baker's lab maybe...

    #StructuralBiology #StructuralBioinformatics

    Announcement: doi.org/10.1038/d41586-024-037

    Code: github.com/google-deepmind/alp

    Hardware requirements: github.com/google-deepmind/alp

    Form to request authorization to use the model weights: forms.gle/svvpY4u2jsHEwWYS6

  28. #DeepMind finally released the code of #AlphaFold3! But with very restrictive conditions to use the model weights... And anyway, I wonder which academic lab has the hardware to run it, beside David Baker's lab maybe...

    #StructuralBiology #StructuralBioinformatics

    Announcement: doi.org/10.1038/d41586-024-037

    Code: github.com/google-deepmind/alp

    Hardware requirements: github.com/google-deepmind/alp

    Form to request authorization to use the model weights: forms.gle/svvpY4u2jsHEwWYS6

  29. #DeepMind finally released the code of #AlphaFold3! But with very restrictive conditions to use the model weights... And anyway, I wonder which academic lab has the hardware to run it, beside maybe David Baker's lab maybe...

    #StructuralBiology #StructuralBioinformatics

    Announcement: doi.org/10.1038/d41586-024-037

    Code: github.com/google-deepmind/alp

    Hardware requirements: github.com/google-deepmind/alp

    Form to request authorization to use the model weights: forms.gle/svvpY4u2jsHEwWYS6

  30. #DeepMind finally released the code of #AlphaFold3! But with very restrictive conditions to use the model weights... And anyway, I wonder which academic lab has the hardware to run it, beside David Baker's lab maybe...

    #StructuralBiology #StructuralBioinformatics

    Announcement: doi.org/10.1038/d41586-024-037

    Code: github.com/google-deepmind/alp

    Hardware requirements: github.com/google-deepmind/alp

    Form to request authorization to use the model weights: forms.gle/svvpY4u2jsHEwWYS6

  31. #DeepMind finally released the code of #AlphaFold3! But with very restrictive conditions to use the model weights... And anyway, I wonder which academic lab has the hardware to run it, beside David Baker's lab maybe...

    #StructuralBiology #StructuralBioinformatics

    Announcement: doi.org/10.1038/d41586-024-037

    Code: github.com/google-deepmind/alp

    Hardware requirements: github.com/google-deepmind/alp

    Form to request authorization to use the model weights: forms.gle/svvpY4u2jsHEwWYS6

  32. So, Bytedance, the people behind tiktok have created protenIx, a pytorch recreation of alphafold 3

    github.com/bytedance/Protenix

    🧪🧬🖥️ #alphafold3 #ai #alphafold

  33. So, Bytedance, the people behind tiktok have created protenIx, a pytorch recreation of alphafold 3

    github.com/bytedance/Protenix

    🧪🧬🖥️

  34. So, Bytedance, the people behind tiktok have created protenIx, a pytorch recreation of alphafold 3

    github.com/bytedance/Protenix

    🧪🧬🖥️ #alphafold3 #ai #alphafold

  35. So, Bytedance, the people behind tiktok have created protenIx, a pytorch recreation of alphafold 3

    github.com/bytedance/Protenix

    🧪🧬🖥️ #alphafold3 #ai #alphafold

  36. Avec mon collègue @AntoineTaly, on a écrit un petit truc pour médecine/sciences pour présenter rapidement les améliorations et restrictions d'#alphafold3 par rapport à #alphafold2

    medecinesciences.org/en/articl

  37. Avec mon collègue @AntoineTaly, on a écrit un petit truc pour médecine/sciences pour présenter rapidement les améliorations et restrictions d'#alphafold3 par rapport à #alphafold2

    medecinesciences.org/en/articl

  38. Avec mon collègue @AntoineTaly, on a écrit un petit truc pour médecine/sciences pour présenter rapidement les améliorations et restrictions d'#alphafold3 par rapport à #alphafold2

    medecinesciences.org/en/articl

  39. Avec mon collègue @AntoineTaly, on a écrit un petit truc pour médecine/sciences pour présenter rapidement les améliorations et restrictions d'#alphafold3 par rapport à #alphafold2

    medecinesciences.org/en/articl

  40. Avec mon collègue @AntoineTaly, on a écrit un petit truc pour médecine/sciences pour présenter rapidement les améliorations et restrictions d'#alphafold3 par rapport à #alphafold2

    medecinesciences.org/en/articl

  41. Does anyone using #Alphafold3 with multiple copies of the same sequence ever get this problem? Basically laying chains exactly on top of each other…in this house we obey the Pauli exclusion principle!

  42. Does anyone using #Alphafold3 with multiple copies of the same sequence ever get this problem? Basically laying chains exactly on top of each other…in this house we obey the Pauli exclusion principle!

  43. Does anyone using #Alphafold3 with multiple copies of the same sequence ever get this problem? Basically laying chains exactly on top of each other…in this house we obey the Pauli exclusion principle!

  44. Does anyone using #Alphafold3 with multiple copies of the same sequence ever get this problem? Basically laying chains exactly on top of each other…in this house we obey the Pauli exclusion principle!

  45. Is anyone doing structure prediction with #AlphaFold3 figured out an easy way to do the relaxation step that Colabfold did? I'm looking into OpenMM and Amber, and making some progress, but it seems like it will be very difficult to make it work when phosphoresidues, ions, or anything else besides standard amino acid residues are included.

    #proteins #structuralbiology #moleculardynamics

  46. Is anyone doing structure prediction with #AlphaFold3 figured out an easy way to do the relaxation step that Colabfold did? I'm looking into OpenMM and Amber, and making some progress, but it seems like it will be very difficult to make it work when phosphoresidues, ions, or anything else besides standard amino acid residues are included.

    #proteins #structuralbiology #moleculardynamics

  47. Is anyone doing structure prediction with #AlphaFold3 figured out an easy way to do the relaxation step that Colabfold did? I'm looking into OpenMM and Amber, and making some progress, but it seems like it will be very difficult to make it work when phosphoresidues, ions, or anything else besides standard amino acid residues are included.

    #proteins #structuralbiology #moleculardynamics

  48. Is anyone doing structure prediction with #AlphaFold3 figured out an easy way to do the relaxation step that Colabfold did? I'm looking into OpenMM and Amber, and making some progress, but it seems like it will be very difficult to make it work when phosphoresidues, ions, or anything else besides standard amino acid residues are included.

    #proteins #structuralbiology #moleculardynamics

  49. Bringing this over from twitter: arxiv.org/abs/2408.16975 - A free and open source of #AlphaFold3 - If this stands true, that would be amazing. 🤞

  50. Bringing this over from twitter: arxiv.org/abs/2408.16975 - A free and open source of #AlphaFold3 - If this stands true, that would be amazing. 🤞