#proteinstructure — Public Fediverse posts

Brute force simulations.

"These proteins should form a pore through which RNA can pass."

Me: Manually places the RNA in the middle of the proteins on a membrane and hopes for a miracle (or a pore).

#compchem #simulation #moleculardynamics #proteinStructure #rna #protein #academicchatter #chemistry #pymol

Brute force simulations.

"These proteins should form a pore through which RNA can pass."

Me: Manually places the RNA in the middle of the proteins on a membrane and hopes for a miracle (or a pore).

#compchem #simulation #moleculardynamics #proteinStructure #rna #protein #academicchatter #chemistry #pymol

Brute force simulations.

"These proteins should form a pore through which RNA can pass."

Me: Manually places the RNA in the middle of the proteins on a membrane and hopes for a miracle (or a pore).

#compchem #simulation #moleculardynamics #proteinStructure #rna #protein #academicchatter #chemistry #pymol

Brute force simulations.

"These proteins should form a pore through which RNA can pass."

Me: Manually places the RNA in the middle of the proteins on a membrane and hopes for a miracle (or a pore).

#compchem #simulation #moleculardynamics #proteinStructure #rna #protein #academicchatter #chemistry #pymol

Brute force simulations.

"These proteins should form a pore through which RNA can pass."

Me: Manually places the RNA in the middle of the proteins on a membrane and hopes for a miracle (or a pore).

#compchem #simulation #moleculardynamics #proteinStructure #rna #protein #academicchatter #chemistry #pymol

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

AI Transforms Scientific Discovery: How AlphaFold and AI Co-Scientist Are Reshaping Research

https://techlife.blog/posts/ai-transforms-scientific-discovery-alphafold-ai-co-scientist/

#AlphaFold #Google #DeepMind #ScientificDiscovery #ProteinStructure #Gemini #NobelPrize #AIResearch #AlphaEvolve #BioNeMo #AI

💊 Can understanding receptor bias help us design safer, more selective GPCR drugs?

🔗 Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.039

📚 CSBJ: https://www.csbj.org/

#GPCR #StructuralBiology #MolecularDynamics #NMR #Pharmacology #ProteinStructure #DrugDiscovery #ComputationalBiology #CellSignaling

🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance?

🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #CryoEM #Thorase #MolecularBiology #mTORC1 #ProteinStructure #Biophysics #AAAplusATPase #SynapticPlasticity #Mitochondria

2024 Nobel in Chemistry for “Designing protein” and “Predicting protein structure”  
One half of the Nobel Prize in Chemistry 2024 has been awarded to David Baker “for computational protein design”............
#AImodel #AlphaFold2 #Aminoacids #DavidBaker #DemisHassabis #JohnJumper #NobelPrizeinChemistry #PROTEIN #Proteindesign #Proteinstructure
SC

https://www.scientificeuropean.co.uk/sciences/chemistry/2024-nobel-in-chemistry-for-designing-protein-and-predicting-protein-structure/

16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406

#science #humans #physiology #proteinstructure

I am excited to introduce our new @EvolLetters paper that has just come out:

https://academic.oup.com/evlett/advance-article/doi/10.1093/evlett/qraf026/8223096

🧵1/7

#temperature #adaptation #enzyme #microbes #ProteinStructure

My PhD research proposal is nearly done after over a month of working on it full tilt. Been an incredible (re)learning experience! Feel so much more comfortable with producing academic style writing again. Had some mega size cobwebs to dust off there. 🕸 Helps to have had to read so many journal articles to grok it all and connect the dots.

Excited to start reaching out to programs and lab heads! ​:neofox_glasses:​ If you happen know folks here on mastodon that are involved in Computational Biology or Biophysics program please drop names in replies or boost for reach. Looking to connect!

Now to treat myself to a much needed rest day and massage for my keyboard-warped back and tired eyed. ♨️
#research #compBio #proteinStructure #molecularDynamics #bioPhysics

Resolution of R-loops and transcription–replication conflicts by SETX–BRCA1–BARD1 complex

Niehrs, C. & Luke, B. Regulatory R-loops as facilitators of gene expression and genome stability. Nat. Rev. Mol.…
#Conflict #Conflicts #War #Biochemistry #BiologicalMicroscopy #cell(biology) #general #geopolitics #LifeSciences #MembraneBiology #ProteinStructure
https://www.europesays.com/2885667/

Pipeline release! nf-core/proteinfold v2.0.0 - Montseny Brook Newt!
Protein 3D structure prediction pipeline
Please see the changelog: https://github.com/nf-core/proteinfold/releases/tag/2.0.0

#alphafold2 #colabfold #esmfold #proteinfoldprediction #proteinfolding #proteinsequences #proteinstructure #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/proteinfold v2.0.0 - Montseny Brook Newt!
Protein 3D structure prediction pipeline
Please see the changelog: https://github.com/nf-core/proteinfold/releases/tag/2.0.0

#alphafold2 #colabfold #esmfold #proteinfoldprediction #proteinfolding #proteinsequences #proteinstructure #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/proteinfold v2.0.0 - Montseny Brook Newt!
Protein 3D structure prediction pipeline
Please see the changelog: https://github.com/nf-core/proteinfold/releases/tag/2.0.0

#alphafold2 #colabfold #esmfold #proteinfoldprediction #proteinfolding #proteinsequences #proteinstructure #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/proteinfold v2.0.0 - Montseny Brook Newt!
Protein 3D structure prediction pipeline
Please see the changelog: https://github.com/nf-core/proteinfold/releases/tag/2.0.0

#alphafold2 #colabfold #esmfold #proteinfoldprediction #proteinfolding #proteinsequences #proteinstructure #nfcore #openscience #nextflow #bioinformatics

Structural Changes in Blood Proteins Could Enable Early Detection of Alzheimer’s Disease

📰 Original title: A surprising blood protein pattern may reveal Alzheimer’s

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/structural-changes-in-blood-proteins-could-enable-early-detection-of-alzheimers-disease/?redirpost=49afce0e-391d-42a6-bd7a-829c3952b1e9

#health #alzheimers #bloodtest #proteinstructure

AI Transforms Scientific Discovery: How AlphaFold and AI Co-Scientist Are Reshaping Research

https://techlife.blog/posts/ai-transforms-scientific-discovery-alphafold-ai-co-scientist/

#AlphaFold #Google #DeepMind #ScientificDiscovery #ProteinStructure #Gemini #NobelPrize #AIResearch #AlphaEvolve #BioNeMo #AI

AI Transforms Scientific Discovery: How AlphaFold and AI Co-Scientist Are Reshaping Research

https://techlife.blog/posts/ai-transforms-scientific-discovery-alphafold-ai-co-scientist/

#AlphaFold #Google #DeepMind #ScientificDiscovery #ProteinStructure #Gemini #NobelPrize #AIResearch #AlphaEvolve #BioNeMo #AI

AI Transforms Scientific Discovery: How AlphaFold and AI Co-Scientist Are Reshaping Research

https://techlife.blog/posts/ai-transforms-scientific-discovery-alphafold-ai-co-scientist/

#AlphaFold #Google #DeepMind #ScientificDiscovery #ProteinStructure #Gemini #NobelPrize #AIResearch #AlphaEvolve #BioNeMo #AI

My PhD research proposal is nearly done after over a month of working on it full tilt. Been an incredible (re)learning experience! Feel so much more comfortable with producing academic style writing again. Had some mega size cobwebs to dust off there. 🕸 Helps to have had to read so many journal articles to grok it all and connect the dots.

Excited to start reaching out to programs and lab heads! ​:neofox_glasses:​ If you happen know folks here on mastodon that are involved in Computational Biology or Biophysics program please drop names in replies or boost for reach. Looking to connect!

Now to treat myself to a much needed rest day and massage for my keyboard-warped back and tired eyed. ♨️
#research #compBio #proteinStructure #molecularDynamics #bioPhysics

My PhD research proposal is nearly done after over a month of working on it full tilt. Been an incredible (re)learning experience! Feel so much more comfortable with producing academic style writing again. Had some mega size cobwebs to dust off there. 🕸 Helps to have had to read so many journal articles to grok it all and connect the dots.

Excited to start reaching out to programs and lab heads! ​:neofox_glasses:​ If you happen know folks here on mastodon that are involved in Computational Biology or Biophysics program please drop names in replies or boost for reach. Looking to connect!

Now to treat myself to a much needed rest day and massage for my keyboard-warped back and tired eyed. ♨️
#research #compBio #proteinStructure #molecularDynamics #bioPhysics

My PhD research proposal is nearly done after over a month of working on it full tilt. Been an incredible (re)learning experience! Feel so much more comfortable with producing academic style writing again. Had some mega size cobwebs to dust off there. 🕸 Helps to have had to read so many journal articles to grok it all and connect the dots.

Excited to start reaching out to programs and lab heads! ​:neofox_glasses:​ If you happen know folks here on mastodon that are involved in Computational Biology or Biophysics program please drop names in replies or boost for reach. Looking to connect!

Now to treat myself to a much needed rest day and massage for my keyboard-warped back and tired eyed. ♨️
#research #compBio #proteinStructure #molecularDynamics #bioPhysics

https://www.europesays.com/ie/198966/ AlphaFold Database Structure Extractor: a web server and API to download AlphaFold structures using common protein accessions | BMC Bioinformatics #algorithms #AlphaFoldDB #APIToolkit #Bioinformatics #ComputationalBiology #ComputationalBiology/Bioinformatics #ComputerAppl.InLifeSciences #Éire #IE #Ireland #Microarrays #NCBI #OpenAccess #ProteinStructure #Science #StructuralGenomics #UniProt

💊 Can understanding receptor bias help us design safer, more selective GPCR drugs?

🔗 Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.039

📚 CSBJ: https://www.csbj.org/

#GPCR #StructuralBiology #MolecularDynamics #NMR #Pharmacology #ProteinStructure #DrugDiscovery #ComputationalBiology #CellSignaling

🧫 What secret molecular choreograph helps bacteria stay resilient against antibiotics and detergents?

🔗 Coordinated subdomain movements of MlaC regulate ligand binding and transport. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.031

📚 CSBJ: https://www.csbj.org/

#Microbiology #AntibioticResistance #MembraneBiology #StructuralBiology #ComputationalChemistry #MolecularDynamics #ComputationalBiology #Biophysics #ProteinStructure #DrugDiscovery #MolecularDocking

🧫 What secret molecular choreograph helps bacteria stay resilient against antibiotics and detergents?

🔗 Coordinated subdomain movements of MlaC regulate ligand binding and transport. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.031

📚 CSBJ: https://www.csbj.org/

#Microbiology #AntibioticResistance #MembraneBiology #StructuralBiology #ComputationalChemistry #MolecularDynamics #ComputationalBiology #Biophysics #ProteinStructure #DrugDiscovery #MolecularDocking

🧫 What secret molecular choreograph helps bacteria stay resilient against antibiotics and detergents?

🔗 Coordinated subdomain movements of MlaC regulate ligand binding and transport. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.031

📚 CSBJ: https://www.csbj.org/

#Microbiology #AntibioticResistance #MembraneBiology #StructuralBiology #ComputationalChemistry #MolecularDynamics #ComputationalBiology #Biophysics #ProteinStructure #DrugDiscovery #MolecularDocking

16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406

#science #humans #physiology #proteinstructure

16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406

#science #humans #physiology #proteinstructure

16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406

#science #humans #physiology #proteinstructure

🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance?

🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #CryoEM #Thorase #MolecularBiology #mTORC1 #ProteinStructure #Biophysics #AAAplusATPase #SynapticPlasticity #Mitochondria

🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance?

🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #CryoEM #Thorase #MolecularBiology #mTORC1 #ProteinStructure #Biophysics #AAAplusATPase #SynapticPlasticity #Mitochondria

Sometimes while reading scientific articles I feel like they just slammed the keyboard randomly.

#AcademicChatter #proteinStructure

Sometimes while reading scientific articles I feel like they just slammed the keyboard randomly.

#AcademicChatter #proteinStructure

Sometimes while reading scientific articles I feel like they just slammed the keyboard randomly.

#AcademicChatter #proteinStructure

Sometimes while reading scientific articles I feel like they just slammed the keyboard randomly.

#AcademicChatter #proteinStructure

I am excited to introduce our new @EvolLetters paper that has just come out:

https://academic.oup.com/evlett/advance-article/doi/10.1093/evlett/qraf026/8223096

🧵1/7

#temperature #adaptation #enzyme #microbes #ProteinStructure

I am excited to introduce our new @EvolLetters paper that has just come out:

https://academic.oup.com/evlett/advance-article/doi/10.1093/evlett/qraf026/8223096

🧵1/7

#temperature #adaptation #enzyme #microbes #ProteinStructure