#thermogenesis — Public Fediverse posts

Snow flies now less mysterious but even more fascinating:

"Coordinated molecular and physiological adaptations enable activity at sub-freezing temperatures in the snow fly Chionea alexandriana", Capek et al. (Stensmyr and Gallio labs).
https://www.cell.com/current-biology/fulltext/S0960-9822(26)00247-2

How they stay alive, balancing resource expenditure and the need to remain not frozen:

"direct measurements reveal that snow flies produce brief bursts of endogenous heat in response to cooling at sub-freezing temperatures, indicating active thermogenic capacity."

And as always, lots to learn, in this case for medicine:

"our results demonstrate that Chionea has evolved mechanisms to cope with high levels of reactive oxygen species (ROS), a byproduct of mitochondrial activity and a hallmark of cold exposure."

#Snowflies #genetics #ColdAdaptations #thermogenesis #Chionea

🔥 Triggering self-combustion in fat cells for weight loss

https://medicalxpress.com/news/2026-02-triggering-combustion-fat-cells-weight.html

#medicine #biology #healthcare #molbio #fat #thermogenesis #metabolism #pharmacology #drugs

I've just gone down a fascinating rabbit hole (as one does)!

In The Vengeance of An, a character mentions that someone else habitually chews on bitter herbs, because people in the North do that to stay warm.

So I looked it up (of course!) and there’s growing evidence that some bitter compounds can stimulate thermogenesis, the process by which your body generates heat and burns calories. This is so cool! 1/n

#TCM #Bitter #BitterHerbs #Thermogenesis

🪤 Cutting key amino acids from mouse diets triggers weight loss through heat burning

https://medicalxpress.com/news/2025-11-key-amino-acids-mouse-diets.html

#diet #weightloss #thermogenesis #biology #mice #aminoacids #bat #brownfat

Through a series of experiments in mice, the team discovered that changing the amount of these amino acids in the animals’ diet produced effects comparable to continuous cold exposure at five degrees Celsius.

#WeightLoss
#thermogenesis
#methionine
#cysteine

Scientists Discover a Diet That Burns Fat Like Cold Exposure, Leading to Significant Weight Loss

By tweaking just two amino acids in the diet, researchers found a way to mimic the fat-burning effects of cold exposure.

Their work centered on two amino acids, methionine and cysteine.

https://scitechdaily.com/scientists-discover-a-diet-that-burns-fat-like-cold-exposure-leading-to-significant-weight-loss/

#WeightLoss
#thermogenesis
#methionine
#cysteine

Mouse studies confirm that diets low in the sulfur-containing amino acids methionine and cysteine increase thermogenesis in beige fat by as much as 20 percent, mimicking the effect of cold exposure.

Summary: https://scitechdaily.com/scientists-discover-a-diet-that-burns-fat-like-cold-exposure-leading-to-significant-weight-loss/

Original paper: https://elifesciences.org/reviewed-preprints/108825v1

#Science #Health #Diet #Thermogenesis #Metabolism

A New Obesity Pill May Burn Fat Without Suppressing Appetite https://www.wired.com/story/new-obesity-pill-may-burn-fat-without-suppressing-appetite/ #Science/Biotech #Science/Health #Thermogenesis #Science

Plant thermogenesis has played key role in attracting pollinating #insects for at least 200 million years https://phys.org/news/2024-09-thermogenesis-played-key-role-pollinating.html

The impact of #thermogenesis on the origin of #insect #pollination https://www.nature.com/articles/s41477-024-01775-z

"This metabolic process allows certain parts of the plant, such as flowers and inflorescences, to raise their temperature above that of the surrounding environment... The heat helps volatilize and disperse floral fragrances and other compounds that attract insects"

.@Moon_Synth_Bio &co show that cellular thermogenesis in #Ecoli is regulated by the #ProteinKinases ArcB, GlnL and YccC, and is related to cellular ATP concentrations; #thermogenesis can be engineered by overexpressing GlnL #PLOSBiology https://plos.io/3s7XdMc

@cellbionews

⬆️ #irisin #Iditarod #autophagy #thermogenesis

Subset of neurons in #hypothalamus increases appetite & decreases #thermogenesis. @JongSohn &co show that ion channel GIRK2 functions in hypothalamic NPY/AgRP neurons to increase energy expenditure in mice and may control body weight @kaistpr #PLOSBiology https://plos.io/3qGa8Ev

@petersuber

Very interesting.
I have been wondering about the body temp drop since the study by Prostiv et al. came out in 2020 [1]
(& also wondering why not more attention has been given to it since it is kind of a big deal).

Futile cycling by Na/K ATPase contributes to thermogenesis [2] & Na/K ATPase activity is lower in autistic ppl. Will have to look up Lachnospiraceae & autism.

1- https://doi.org/10.7554/eLife.49555

2- https://rhyobrain.blogspot.com/2020/06/nak-atpase-thermogenesis-energetic-cost.html

#thermogenesis #microbiome #physiology