#telomerase — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #telomerase, aggregated by home.social.
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https://www.europesays.com/ie/470630/ Human telomerase shows limited function across different animal species #Aging #Cell #DNA #Éire #Enzyme #Genome #IE #Ireland #Preclinical #Protein #Reproduction #Research #Science #Telomerase #Telomere
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Dysfunction in chromosome-stabilizing protein identified as a cause of deadly illnesses
New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in…
#NewsBeep #News #Science #AU #Australia #biochemistry #Bone #BoneMarrow #dna #Genetic #geneticinformation #protein #research #Telomerase #Telomere
https://www.newsbeep.com/au/254539/ -
https://www.europesays.com/ie/156377/ Dysfunction in chromosome-stabilizing protein identified as a cause of deadly illnesses #Biochemistry #Bone #BoneMarrow #DNA #Éire #Genetic #GeneticInformation #IE #Ireland #Protein #Research #Science #Telomerase #Telomere
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https://www.europesays.com/uk/486310/ Innovative system accurately detects genetic mutations in the brain tumor within 25 minutes #brain #BrainTumor #Diagnostic #DNA #Genetic #Genetics #Genotyping #Glioma #NeuroOncology #oncology #promoter #Research #ReverseTranscriptase #SangerSequencing #Science #Surgery #Technology #Telomerase #Tumor #UK #UnitedKingdom
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Vitamin D May Help Slow Aging, Study Finds
Could a simple vitamin help slow the ticking of our biological clocks? A new study suggests vitamin D…
#NewsBeep #News #Nutrition #Aging #AU #Australia #Health #longevity #Telomerase #TheConversation #Vitamins
https://www.newsbeep.com/au/142367/ -
Vitamin D May Help Slow Aging, Study Finds
Could a simple vitamin help slow the ticking of our biological clocks? A new study suggests vitamin D may protect the delicate chromosome caps linked to aging, potentially lowering the risk of age-related diseases. Credit: Stock A clinical trial suggests vitamin …
#dining #cooking #diet #food #Nutrition #aging #longevity #nutrition #Telomerase #TheConversation #Vitamins
https://www.diningandcooking.com/2283295/vitamin-d-may-help-slow-aging-study-finds/ -
Vitamin D May Help Slow Aging, Study Finds
Could a simple vitamin help slow the ticking of our biological clocks? A new study suggests vitamin D may protect the delicate chromosome caps linked to aging, potentially lowering the risk of age-related diseases. Credit: Stock A clinical trial suggests vitamin …
#dining #cooking #diet #food #Nutrition #aging #longevity #nutrition #Telomerase #TheConversation #Vitamins
https://www.diningandcooking.com/2283295/vitamin-d-may-help-slow-aging-study-finds/ -
Vitamin D May Help Slow Aging, Study Finds
Could a simple vitamin help slow the ticking of our biological clocks? A new study suggests vitamin D may protect the delicate chromosome caps linked to aging, potentially lowering the risk of age-related diseases. Credit: Stock A clinical trial suggests vitamin …
#dining #cooking #diet #food #Nutrition #aging #longevity #nutrition #Telomerase #TheConversation #Vitamins
https://www.diningandcooking.com/2283295/vitamin-d-may-help-slow-aging-study-finds/ -
Vitamin D May Help Slow Aging, Study Finds
Could a simple vitamin help slow the ticking of our biological clocks? A new study suggests vitamin D may protect the delicate chromosome caps linked to aging, potentially lowering the risk of age-related diseases. Credit: Stock A clinical trial suggests vitamin …
#dining #cooking #diet #food #Nutrition #aging #longevity #nutrition #Telomerase #TheConversation #Vitamins
https://www.diningandcooking.com/2283295/vitamin-d-may-help-slow-aging-study-finds/ -
Vitamin D May Help Slow Aging, Study Finds https://www.diningandcooking.com/2283295/vitamin-d-may-help-slow-aging-study-finds/ #aging #longevity #nutrition #Telomerase #TheConversation #Vitamins
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Vitamin D May Help Slow Aging, Study Finds https://www.diningandcooking.com/2283295/vitamin-d-may-help-slow-aging-study-finds/ #aging #longevity #nutrition #Telomerase #TheConversation #Vitamins
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Vitamin D May Help Slow Aging, Study Finds https://www.diningandcooking.com/2283295/vitamin-d-may-help-slow-aging-study-finds/ #aging #longevity #nutrition #Telomerase #TheConversation #Vitamins
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https://www.europesays.com/uk/423167/ Vitamin D May Help Slow Aging, Study Finds #Aging #Health #Longevity #Nutrition #Telomerase #TheConversation #UK #UnitedKingdom #Vitamins
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Vitamin D May Help Slow Aging, Study Finds
Could a simple vitamin help slow the ticking of our biological clocks? A new study suggests vitamin D…
#NewsBeep #News #Nutrition #aging #Health #longevity #Telomerase #TheConversation #UK #UnitedKingdom #Vitamins
https://www.newsbeep.com/uk/136230/ -
Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq.
#Telomerase #hTR #hTERT #DMS-MaPseq #RNA
https://www.nature.com/articles/s41467-025-56149-6 -
Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq.
#Telomerase #hTR #hTERT #DMS-MaPseq #RNA
https://www.nature.com/articles/s41467-025-56149-6 -
Study reveals how #cells keep #telomerase in check.
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Study reveals how #cells keep #telomerase in check.
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"Unexpectedly, approximately 15% of the steady state population of hTR has a CR4/5 conformation lacking features required for hTERT binding. Mutagenesis demonstrates that stabilization of the alternative CR4/5 conformation is detrimental to telomerase assembly and activity. We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded."
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"Unexpectedly, approximately 15% of the steady state population of hTR has a CR4/5 conformation lacking features required for hTERT binding. Mutagenesis demonstrates that stabilization of the alternative CR4/5 conformation is detrimental to telomerase assembly and activity. We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded."
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"Unexpectedly, approximately 15% of the steady state population of hTR has a CR4/5 conformation lacking features required for hTERT binding. Mutagenesis demonstrates that stabilization of the alternative CR4/5 conformation is detrimental to telomerase assembly and activity. We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded."
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"Unexpectedly, approximately 15% of the steady state population of hTR has a CR4/5 conformation lacking features required for hTERT binding. Mutagenesis demonstrates that stabilization of the alternative CR4/5 conformation is detrimental to telomerase assembly and activity. We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded."
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The Advances Neuroblastoma Research meeting #anr2023 has kicked off, Lisa Werr showing the role of #telomerase / #TERT in #neuroblastoma in mice and humans in the first talk.
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The Advances Neuroblastoma Research meeting #anr2023 has kicked off, Lisa Werr showing the role of #telomerase / #TERT in #neuroblastoma in mice and humans in the first talk.
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The Advances Neuroblastoma Research meeting #anr2023 has kicked off, Lisa Werr showing the role of #telomerase / #TERT in #neuroblastoma in mice and humans in the first talk.
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The Advances Neuroblastoma Research meeting #anr2023 has kicked off, Lisa Werr showing the role of #telomerase / #TERT in #neuroblastoma in mice and humans in the first talk.
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@WhatisBiotechnology More on #telomerase 🧬 ⬇️
“Chemical Eye 👁️ on Motherly 👵 Love 💕” 👉 http://www.sitnews.us/MacDougall/050705_macdougall.html
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@WhatisBiotechnology More on #telomerase 🧬 ⬇️
“Chemical Eye 👁️ on Motherly 👵 Love 💕” 👉 http://www.sitnews.us/MacDougall/050705_macdougall.html
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@WhatisBiotechnology More on #telomerase 🧬 ⬇️
“Chemical Eye 👁️ on Motherly 👵 Love 💕” 👉 http://www.sitnews.us/MacDougall/050705_macdougall.html
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@WhatisBiotechnology More on #telomerase 🧬 ⬇️
“Chemical Eye 👁️ on Motherly 👵 Love 💕” 👉 http://www.sitnews.us/MacDougall/050705_macdougall.html
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A new substrate for Telomerase?
By visualizing telomerase activity on telomeric replication forks we provide strong evidence in support of a hypothesis that has been lingering for a while in the field. #Telomere #Telomerase
@academicchatter @academicsunite
https://www.science.org/doi/10.1126/sciadv.adf2011 -
'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'
#Preprint #Telomeres #telomerase
https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas
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'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'
#Preprint #Telomeres #telomerase
https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas
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'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'
#Preprint #Telomeres #telomerase
https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas
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'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'
#Preprint #Telomeres #telomerase
https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas
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A paper that I was not aware of in @embojournal that scientific editor @HVodermaier mentioned in the #telomerase independent immortalisation discussion on the latest #EMBOPodcast episode is the finding from Lackner, Karlseder et al in #EMBOJournal 2012 of a very interesting ALT system in #Celegans
🎧 to the episode
https://www.embo.org/podcasts/alternative-immortality/Read the paper (#OpenAccess)
https://www.embopress.org/doi/full/10.1038/emboj.2012.61 -
A paper that I was not aware of in @embojournal that scientific editor @HVodermaier mentioned in the #telomerase independent immortalisation discussion on the latest #EMBOPodcast episode is the finding from Lackner, Karlseder et al in #EMBOJournal 2012 of a very interesting ALT system in #Celegans
🎧 to the episode
https://www.embo.org/podcasts/alternative-immortality/Read the paper (#OpenAccess)
https://www.embopress.org/doi/full/10.1038/emboj.2012.61 -
A paper that I was not aware of in @embojournal that scientific editor @HVodermaier mentioned in the #telomerase independent immortalisation discussion on the latest #EMBOPodcast episode is the finding from Lackner, Karlseder et al in #EMBOJournal 2012 of a very interesting ALT system in #Celegans
🎧 to the episode
https://www.embo.org/podcasts/alternative-immortality/Read the paper (#OpenAccess)
https://www.embopress.org/doi/full/10.1038/emboj.2012.61 -
A paper that I was not aware of in @embojournal that scientific editor @HVodermaier mentioned in the #telomerase independent immortalisation discussion on the latest #EMBOPodcast episode is the finding from Lackner, Karlseder et al in #EMBOJournal 2012 of a very interesting ALT system in #Celegans
🎧 to the episode
https://www.embo.org/podcasts/alternative-immortality/Read the paper (#OpenAccess)
https://www.embopress.org/doi/full/10.1038/emboj.2012.61 -
Just Published!
"Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity"
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Just Published!
"Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity"
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Just Published!
"Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity"
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Just Published!
"Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity"
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Just Published!
"Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity"
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The latest episode of the EMBO Podcast #EMBOPodcast is out 🎧
I spoke with Roger Reddel & Tracy Bryan at Sydney's Children's Medical Research Institute about their classic 1995 @embojournal paper describing #telomerase independent #telomere lengthening in immortalised cell lines. It challenged conventional wisdom at the time - and it was Bryan's PhD project, quite a way to get started in science.
@miguelgf provided some perspective on the work and its enduring significance and editor @HVodermaier explained #EMBOJournal's interest in studies with striking findings that may not provide a full mechanistic description.
You can listen to "ALTernative immortality" at the link below or on your preferred podcast app. Special thanks to Igor Jukic & audio producer extraordinaire @marcoantonio
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The latest episode of the EMBO Podcast #EMBOPodcast is out 🎧
I spoke with Roger Reddel & Tracy Bryan at Sydney's Children's Medical Research Institute about their classic 1995 @embojournal paper describing #telomerase independent #telomere lengthening in immortalised cell lines. It challenged conventional wisdom at the time - and it was Bryan's PhD project, quite a way to get started in science.
@miguelgf provided some perspective on the work and its enduring significance and editor @HVodermaier explained #EMBOJournal's interest in studies with striking findings that may not provide a full mechanistic description.
You can listen to "ALTernative immortality" at the link below or on your preferred podcast app. Special thanks to Igor Jukic & audio producer extraordinaire @marcoantonio
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The latest episode of the EMBO Podcast #EMBOPodcast is out 🎧
I spoke with Roger Reddel & Tracy Bryan at Sydney's Children's Medical Research Institute about their classic 1995 @embojournal paper describing #telomerase independent #telomere lengthening in immortalised cell lines. It challenged conventional wisdom at the time - and it was Bryan's PhD project, quite a way to get started in science.
@miguelgf provided some perspective on the work and its enduring significance and editor @HVodermaier explained #EMBOJournal's interest in studies with striking findings that may not provide a full mechanistic description.
You can listen to "ALTernative immortality" at the link below or on your preferred podcast app. Special thanks to Igor Jukic & audio producer extraordinaire @marcoantonio
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The latest episode of the EMBO Podcast #EMBOPodcast is out 🎧
I spoke with Roger Reddel & Tracy Bryan at Sydney's Children's Medical Research Institute about their classic 1995 @embojournal paper describing #telomerase independent #telomere lengthening in immortalised cell lines. It challenged conventional wisdom at the time - and it was Bryan's PhD project, quite a way to get started in science.
@miguelgf provided some perspective on the work and its enduring significance and editor @HVodermaier explained #EMBOJournal's interest in studies with striking findings that may not provide a full mechanistic description.
You can listen to "ALTernative immortality" at the link below or on your preferred podcast app. Special thanks to Igor Jukic & audio producer extraordinaire @marcoantonio
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Including comments from #telomerase researcher Miguel Godinho Ferreira at IRCAN Nice and @embojournal genome stability & dynamics editor @HVodermaier
Re-read the original article for free in our #anniversary collection:
https://www.embopress.org/page/journal/14602075/focus/40th-anniversary -
Including comments from #telomerase researcher Miguel Godinho Ferreira at IRCAN Nice and @embojournal genome stability & dynamics editor @HVodermaier
Re-read the original article for free in our #anniversary collection:
https://www.embopress.org/page/journal/14602075/focus/40th-anniversary