#telomeres — Public Fediverse posts

Noticed an excessively long label peeling off a flask today. This telomere analogy sprang to mind:

#Chromosomes #Telomeres #Humor #ScienceHumor #Biology

Noticed an excessively long label peeling off a flask today. This telomere analogy sprang to mind:

#Chromosomes #Telomeres #Humor #ScienceHumor #Biology

The Vitamin You Should Be Taking to Support Healthy Aging

This Vitamin Supports Healthy Aging insta_photos – Getty Images “Hearst Magazines and Yahoo may earn commission or revenue…
#NewsBeep #News #Nutrition #biologicalaging #CA #Canada #cellularaging #Health #healthyaging #Inflammation #shortening #telomeres #vitamind #Vitamind3
https://www.newsbeep.com/ca/393386/

https://www.europesays.com/ie/271765/ The Vitamin You Should Be Taking to Support Healthy Aging #BiologicalAging #CellularAging #Éire #Health #HealthyAging #IE #inflammation #Ireland #Nutrition #shortening #telomeres #VitaminD #VitaminD3

https://www.europesays.com/fr/520889/ Et si ce que vous buviez chaque jour faisait vieillir votre corps plus vite ? #AdditifsAlimentaires #Alimentation #BoissonSucrée #cellules #Chromosomes #CorpsHumain #FR #France #Fructose #Health #InflammationChronique #Infusion #LesTendances #longévité #LongueurDesTélomères #MétabolismeCellulaire #Mitochondries #PicGlycémique #Santé #sodas #StressOxydatif #Télomères #ThéVert #Tisane #vieillissement #VieillissementCellulaire

“Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.” #isogg #Harvard #geneadons #dna #VITAL #vitaminD #telomeres #epigenetics https://news.harvard.edu/gazette/story/2025/05/vitamin-d-supplements-may-slow-biological-aging/

How Tiny Molecular Machines Keep Our Cells Alive and Thriving

#CellBiology #AgingScience #Telomeres #OxidativeStress #Mitochondria #CircadianRhythms #StemCells #Genetics #CancerResearch #HealthAndWellness

https://youtube.com/shorts/B8zklp2WQsg?feature=share

How Tiny Molecular Machines Keep Our Cells Alive and Thriving

#CellBiology #AgingScience #Telomeres #OxidativeStress #Mitochondria #CircadianRhythms #StemCells #Genetics #CancerResearch #HealthAndWellness

https://youtube.com/shorts/B8zklp2WQsg?feature=share

How Tiny Molecular Machines Keep Our Cells Alive and Thriving

#CellBiology #AgingScience #Telomeres #OxidativeStress #Mitochondria #CircadianRhythms #StemCells #Genetics #CancerResearch #HealthAndWellness

https://youtube.com/shorts/B8zklp2WQsg?feature=share

I just learned that #NationalDNAday in the #UnitedStates was yesterday. I hope it's not too late to celebrate with some eye-candy depicting the hydrogen-bonding of a guanine quadruplex found in #DNA 🧬 #telomeres.

Explanation here: https://theacademic.com/unravelling-the-hydrogen-bonding-patterns-in-telomeric-g-quadruplexes-from-structure-to-function/

I just learned that #NationalDNAday in the #UnitedStates was yesterday. I hope it's not too late to celebrate with some eye-candy depicting the hydrogen-bonding of a guanine quadruplex found in #DNA 🧬 #telomeres.

Explanation here: https://theacademic.com/unravelling-the-hydrogen-bonding-patterns-in-telomeric-g-quadruplexes-from-structure-to-function/

I just learned that #NationalDNAday in the #UnitedStates was yesterday. I hope it's not too late to celebrate with some eye-candy depicting the hydrogen-bonding of a guanine quadruplex found in #DNA 🧬 #telomeres.

Explanation here: https://theacademic.com/unravelling-the-hydrogen-bonding-patterns-in-telomeric-g-quadruplexes-from-structure-to-function/

I just learned that #NationalDNAday in the #UnitedStates was yesterday. I hope it's not too late to celebrate with some eye-candy depicting the hydrogen-bonding of a guanine quadruplex found in #DNA 🧬 #telomeres.

Explanation here: https://theacademic.com/unravelling-the-hydrogen-bonding-patterns-in-telomeric-g-quadruplexes-from-structure-to-function/

I just learned that #NationalDNAday in the #UnitedStates was yesterday. I hope it's not too late to celebrate with some eye-candy depicting the hydrogen-bonding of a guanine quadruplex found in #DNA 🧬 #telomeres.

Explanation here: https://theacademic.com/unravelling-the-hydrogen-bonding-patterns-in-telomeric-g-quadruplexes-from-structure-to-function/

#Bacterial ' #jumping_genes' can target and control #chromosome ends.

#transposons #telomeres #Streptomyces #genomes

https://phys.org/news/2025-03-bacterial-genes-chromosome.html

#Bacterial ' #jumping_genes' can target and control #chromosome ends.

#transposons #telomeres #Streptomyces #genomes

https://phys.org/news/2025-03-bacterial-genes-chromosome.html

#Bacterial ' #jumping_genes' can target and control #chromosome ends.

#transposons #telomeres #Streptomyces #genomes

https://phys.org/news/2025-03-bacterial-genes-chromosome.html

#Bacterial ' #jumping_genes' can target and control #chromosome ends.

#transposons #telomeres #Streptomyces #genomes

https://phys.org/news/2025-03-bacterial-genes-chromosome.html

#Bacterial ' #jumping_genes' can target and control #chromosome ends.

#transposons #telomeres #Streptomyces #genomes

https://phys.org/news/2025-03-bacterial-genes-chromosome.html

#Data-driven techniques enhance understanding of #cell division.

#mitosis #transposons #Telomeres #chromatin

https://phys.org/news/2025-02-driven-techniques-cell-division.html

#Data-driven techniques enhance understanding of #cell division.

#mitosis #transposons #Telomeres #chromatin

https://phys.org/news/2025-02-driven-techniques-cell-division.html

Go Nuts for a longer life.

Greens, Green Tea, and Nuts Put to the Test for Telomeres
https://www.youtube.com/watch?v=SculWYzztSU

#NutritionFacts #DrMichaelGreger #Telomeres

Go Nuts for a longer life.

Greens, Green Tea, and Nuts Put to the Test for Telomeres
https://www.youtube.com/watch?v=SculWYzztSU

#NutritionFacts #DrMichaelGreger #Telomeres

Go Nuts for a longer life.

Greens, Green Tea, and Nuts Put to the Test for Telomeres
https://www.youtube.com/watch?v=SculWYzztSU

#NutritionFacts #DrMichaelGreger #Telomeres

Go Nuts for a longer life.

Greens, Green Tea, and Nuts Put to the Test for Telomeres
https://www.youtube.com/watch?v=SculWYzztSU

#NutritionFacts #DrMichaelGreger #Telomeres

Go Nuts for a longer life.

Greens, Green Tea, and Nuts Put to the Test for Telomeres
https://www.youtube.com/watch?v=SculWYzztSU

#NutritionFacts #DrMichaelGreger #Telomeres

"Unexpectedly, approximately 15% of the steady state population of hTR has a CR4/5 conformation lacking features required for hTERT binding. Mutagenesis demonstrates that stabilization of the alternative CR4/5 conformation is detrimental to telomerase assembly and activity. We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded."

#Preprint #Telomeres #Telomerase

https://www.biorxiv.org/content/10.1101/2023.10.04.560962v1

"Unexpectedly, approximately 15% of the steady state population of hTR has a CR4/5 conformation lacking features required for hTERT binding. Mutagenesis demonstrates that stabilization of the alternative CR4/5 conformation is detrimental to telomerase assembly and activity. We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded."

#Preprint #Telomeres #Telomerase

https://www.biorxiv.org/content/10.1101/2023.10.04.560962v1

"Unexpectedly, approximately 15% of the steady state population of hTR has a CR4/5 conformation lacking features required for hTERT binding. Mutagenesis demonstrates that stabilization of the alternative CR4/5 conformation is detrimental to telomerase assembly and activity. We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded."

#Preprint #Telomeres #Telomerase

https://www.biorxiv.org/content/10.1101/2023.10.04.560962v1

"Unexpectedly, approximately 15% of the steady state population of hTR has a CR4/5 conformation lacking features required for hTERT binding. Mutagenesis demonstrates that stabilization of the alternative CR4/5 conformation is detrimental to telomerase assembly and activity. We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded."

#Preprint #Telomeres #Telomerase

https://www.biorxiv.org/content/10.1101/2023.10.04.560962v1

'Pot1 is a subunit of telomere capping complex that binds to the G-rich overhang and inhibits the activation of DNA damage checkpoints. In this study, we explore new functions of fission yeast Pot1 by using a pot1-1 temperature sensitive mutant'
@miguelgf et al

#telomeres #telomere

https://www.biorxiv.org/content/10.1101/2023.01.23.525167v1

'Pot1 is a subunit of telomere capping complex that binds to the G-rich overhang and inhibits the activation of DNA damage checkpoints. In this study, we explore new functions of fission yeast Pot1 by using a pot1-1 temperature sensitive mutant'
@miguelgf et al

#telomeres #telomere

https://www.biorxiv.org/content/10.1101/2023.01.23.525167v1

'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'

#Preprint #Telomeres #telomerase

https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas

'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'

#Preprint #Telomeres #telomerase

https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas

'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'

#Preprint #Telomeres #telomerase

https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas

'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'

#Preprint #Telomeres #telomerase

https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas

#Telomeres #Telomerase #tumorigenesis #Preprint from Charles Kinzig, Titia de Lange et al

"Here, we aimed to determine whether telomerase can add telomeric DNA to DSBs in human cells and how this process is regulated. The data indicate that telomerase can create a functional neotelomere at a Cas9-induced DSB that bears the TS sequence at one 3′ end. The frequency of neotelomere formation is increased upon overexpression of telomerase, suggesting that the low level of telomerase in most human cells minimizes these deleterious events. In addition, neotelomere formation is inhibited by ATR signaling at resected DSBs. We discuss these findings in the context of genome instability during tumorigenesis, where neotelomere formation by telomerase might end BFB cycles as originally proposed by McClintock."

https://www.biorxiv.org/content/10.1101/2022.10.31.514589v1

#Telomeres #Telomerase #tumorigenesis #Preprint from Charles Kinzig, Titia de Lange et al

"Here, we aimed to determine whether telomerase can add telomeric DNA to DSBs in human cells and how this process is regulated. The data indicate that telomerase can create a functional neotelomere at a Cas9-induced DSB that bears the TS sequence at one 3′ end. The frequency of neotelomere formation is increased upon overexpression of telomerase, suggesting that the low level of telomerase in most human cells minimizes these deleterious events. In addition, neotelomere formation is inhibited by ATR signaling at resected DSBs. We discuss these findings in the context of genome instability during tumorigenesis, where neotelomere formation by telomerase might end BFB cycles as originally proposed by McClintock."

https://www.biorxiv.org/content/10.1101/2022.10.31.514589v1

#Telomeres #Telomerase #tumorigenesis #Preprint from Charles Kinzig, Titia de Lange et al

"Here, we aimed to determine whether telomerase can add telomeric DNA to DSBs in human cells and how this process is regulated. The data indicate that telomerase can create a functional neotelomere at a Cas9-induced DSB that bears the TS sequence at one 3′ end. The frequency of neotelomere formation is increased upon overexpression of telomerase, suggesting that the low level of telomerase in most human cells minimizes these deleterious events. In addition, neotelomere formation is inhibited by ATR signaling at resected DSBs. We discuss these findings in the context of genome instability during tumorigenesis, where neotelomere formation by telomerase might end BFB cycles as originally proposed by McClintock."

https://www.biorxiv.org/content/10.1101/2022.10.31.514589v1