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#spliceosome — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #spliceosome, aggregated by home.social.

  1. "Most importantly, by proving that the evolutionarily-conserved RNA core of splicing machines can recognize small molecules specifically, our work provides a solid basis for the rational design of splicing modulators not only against bacterial and organellar introns, but also against the human spliceosome, which is a validated drug target for the treatment of congenital diseases and cancers." #spliceosome #splicing #intron #introns #transcription #ribonucleicAcid #RNA

    nature.com/articles/s41467-024

  2. LncRNA FLAIL affects alternative #splicing and represses flowering in #Arabidopsis

    Sebastian Marquardt and coworkers identify #FLAIL as a trans-acting #lncRNA that targets the #spliceosome and regulates plant #flowering by promoting expression of the #laccase LAC8

    embopress.org/doi/10.15252/emb