#metabolic — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #metabolic, aggregated by home.social.
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How can #metabolic & #environmental cues modulate the #DNAdamage response? María Moriel-Carretero et al find master kinase #Tel1/ATM to bind #PI4P at the #Golgi, altering its availability in the nucleus and impacting kinetics, intensity and persistence of DNA DSB responses in yeast and human cells
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Keisuke Shigeta et al (Keio University School of Medicine) analyze #metabolic alterations leading to #chemoresistance in #urothelial cancer #bladdercancer: #IDH2 gain-of-function independent of #mutation is responsible for #HIF1α-dependent production of respective #gemcitabine and #CDDP competitors #dCTP and #NADPH