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  1. Tannier et al. simulated horizontal gene transfer (HGT) with ghost lineages, finding that, when only 1% of potential donors are sampled, ca. 50% of SPR-inferred HGTs misidentify donors.

    🔗 doi.org/10.1093/molbev/msaf128

    #evobio #HGT

  2. Tannier et al. simulated horizontal gene transfer (HGT) with ghost lineages, finding that, when only 1% of potential donors are sampled, ca. 50% of SPR-inferred HGTs misidentify donors.

    🔗 doi.org/10.1093/molbev/msaf128

    #evobio #HGT

  3. Tannier et al. simulated horizontal gene transfer (HGT) with ghost lineages, finding that, when only 1% of potential donors are sampled, ca. 50% of SPR-inferred HGTs misidentify donors.

    🔗 doi.org/10.1093/molbev/msaf128

    #evobio #HGT

  4. Tannier et al. simulated horizontal gene transfer (HGT) with ghost lineages, finding that, when only 1% of potential donors are sampled, ca. 50% of SPR-inferred HGTs misidentify donors.

    🔗 doi.org/10.1093/molbev/msaf128

    #evobio #HGT

  5. Tannier et al. simulated horizontal gene transfer (HGT) with ghost lineages, finding that, when only 1% of potential donors are sampled, ca. 50% of SPR-inferred HGTs misidentify donors.

    🔗 doi.org/10.1093/molbev/msaf128

    #evobio #HGT

  6. The #diatom genus Nitzschia lost photosynthesis to become free-living heterotrophs. This study shows how #HGT from marine bacteria, followed by #GeneDuplication & #neofunctionalization, allowed them to catabolize #alginate & live off brown algal polysaccharides @PLOSBiology plos.io/41WaW8e

  7. The #diatom genus Nitzschia lost photosynthesis to become free-living heterotrophs. This study shows how #HGT from marine bacteria, followed by #GeneDuplication & #neofunctionalization, allowed them to catabolize #alginate & live off brown algal polysaccharides @PLOSBiology plos.io/41WaW8e

  8. The #diatom genus Nitzschia lost photosynthesis to become free-living heterotrophs. This study shows how #HGT from marine bacteria, followed by #GeneDuplication & #neofunctionalization, allowed them to catabolize #alginate & live off brown algal polysaccharides @PLOSBiology plos.io/41WaW8e

  9. The #diatom genus Nitzschia lost photosynthesis to become free-living heterotrophs. This study shows how #HGT from marine bacteria, followed by #GeneDuplication & #neofunctionalization, allowed them to catabolize #alginate & live off brown algal polysaccharides @PLOSBiology plos.io/41WaW8e

  10. The #diatom genus Nitzschia lost photosynthesis to become free-living heterotrophs. This study shows how #HGT from marine bacteria, followed by #GeneDuplication & #neofunctionalization, allowed them to catabolize #alginate & live off brown algal polysaccharides @PLOSBiology plos.io/41WaW8e

  11. Historical outbreaks of #CoffeeWilt disease linked to gene transfer from another fungus phys.org/news/2024-12-historic

    Horizontal transfers between fungal #Fusarium species contributed to successive outbreaks of #coffee wilt disease: Lily Peck et al. journals.plos.org/plosbiology/

    "The #fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive outbreaks of the disease."

    #Fungi #PlantPathology #LGT #HGT #Evolution #Biology

  12. Historical outbreaks of #CoffeeWilt disease linked to gene transfer from another fungus phys.org/news/2024-12-historic

    Horizontal transfers between fungal #Fusarium species contributed to successive outbreaks of #coffee wilt disease: Lily Peck et al. journals.plos.org/plosbiology/

    "The #fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive outbreaks of the disease."

    #Fungi #PlantPathology #LGT #HGT #Evolution #Biology

  13. Historical outbreaks of #CoffeeWilt disease linked to gene transfer from another fungus phys.org/news/2024-12-historic

    Horizontal transfers between fungal #Fusarium species contributed to successive outbreaks of #coffee wilt disease: Lily Peck et al. journals.plos.org/plosbiology/

    "The #fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive outbreaks of the disease."

    #Fungi #PlantPathology #LGT #HGT #Evolution #Biology

  14. Historical outbreaks of #CoffeeWilt disease linked to gene transfer from another fungus phys.org/news/2024-12-historic

    Horizontal transfers between fungal #Fusarium species contributed to successive outbreaks of #coffee wilt disease: Lily Peck et al. journals.plos.org/plosbiology/

    "The #fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive outbreaks of the disease."

    #Fungi #PlantPathology #LGT #HGT #Evolution #Biology

  15. Historical outbreaks of #CoffeeWilt disease linked to gene transfer from another fungus phys.org/news/2024-12-historic

    Horizontal transfers between fungal #Fusarium species contributed to successive outbreaks of #coffee wilt disease: Lily Peck et al. journals.plos.org/plosbiology/

    "The #fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive outbreaks of the disease."

    #Fungi #PlantPathology #LGT #HGT #Evolution #Biology

  16. How do "ghost" lineages impact use of branch length methods to infer timing of #HGT events? @toni_gabaldon &co discuss key considerations regarding the potential effect of such missing lineages: plos.io/4crpJLl Response by @damdevienne &co: plos.io/49YqVEl

  17. How do "ghost" lineages impact use of branch length methods to infer timing of #HGT events? @toni_gabaldon &co discuss key considerations regarding the potential effect of such missing lineages: plos.io/4crpJLl Response by @damdevienne &co: plos.io/49YqVEl

  18. How do "ghost" lineages impact use of branch length methods to infer timing of #HGT events? @toni_gabaldon &co discuss key considerations regarding the potential effect of such missing lineages: plos.io/4crpJLl Response by @damdevienne &co: plos.io/49YqVEl

  19. How do "ghost" lineages impact use of branch length methods to infer timing of #HGT events? @toni_gabaldon &co discuss key considerations regarding the potential effect of such missing lineages: plos.io/4crpJLl Response by @damdevienne &co: plos.io/49YqVEl

  20. How do "ghost" lineages impact use of branch length methods to infer timing of #HGT events? @toni_gabaldon &co discuss key considerations regarding the potential effect of such missing lineages: plos.io/4crpJLl Response by @damdevienne &co: plos.io/49YqVEl

  21. It's official, the final version of our newest research is out in The ISME Journal: "Bacteria use a catabolic patchwork pathway of apparently recent origin for degradation of the synthetic buffer compound TRIS"

    Read all about how #Pseudomonas and other #bacteria have learned to eat our well-beloved #TRIS buffer.

    doi.org/10.1093/ismejo/wrad023

    #microbiology #catabolism #ISME #HGT #plasmid #OA #evolution

  22. It's official, the final version of our newest research is out in The ISME Journal: "Bacteria use a catabolic patchwork pathway of apparently recent origin for degradation of the synthetic buffer compound TRIS"

    Read all about how #Pseudomonas and other #bacteria have learned to eat our well-beloved #TRIS buffer.

    doi.org/10.1093/ismejo/wrad023

    #microbiology #catabolism #ISME #HGT #plasmid #OA #evolution

  23. It's official, the final version of our newest research is out in The ISME Journal: "Bacteria use a catabolic patchwork pathway of apparently recent origin for degradation of the synthetic buffer compound TRIS"

    Read all about how #Pseudomonas and other #bacteria have learned to eat our well-beloved #TRIS buffer.

    doi.org/10.1093/ismejo/wrad023

    #microbiology #catabolism #ISME #HGT #plasmid #OA #evolution

  24. It's official, the final version of our newest research is out in The ISME Journal: "Bacteria use a catabolic patchwork pathway of apparently recent origin for degradation of the synthetic buffer compound TRIS"

    Read all about how #Pseudomonas and other #bacteria have learned to eat our well-beloved #TRIS buffer.

    doi.org/10.1093/ismejo/wrad023

    #microbiology #catabolism #ISME #HGT #plasmid #OA #evolution

  25. Ich bin gerade in der RB 14322 von #HGT nach #HBS in der /NI:RB46 auf der $1920 und $1812 #travelynx travelynx.de/status/nortix/169

  26. Ich bin gerade in der RB 14322 von #HGT nach #HBS in der /NI:RB46 auf der $1920 und $1812 #travelynx travelynx.de/status/nortix/169

  27. Ich bin gerade in der RB 14322 von #HGT nach #HBS in der /NI:RB46 auf der $1920 und $1812 #travelynx travelynx.de/status/nortix/169

  28. Ever wondered why your #TRIS-buffered solutions turn turbid on the shelf so quickly? Look no further, it’s #pseudomonas. new study from our lab out as a preprint describing a complete TRIS degradation pathway in #bacteria biorxiv.org/content/10.1101/20 #microbiology #HGT #biorxiv

  29. Ever wondered why your #TRIS-buffered solutions turn turbid on the shelf so quickly? Look no further, it’s #pseudomonas. new study from our lab out as a preprint describing a complete TRIS degradation pathway in #bacteria biorxiv.org/content/10.1101/20 #microbiology #HGT #biorxiv

  30. Ever wondered why your #TRIS-buffered solutions turn turbid on the shelf so quickly? Look no further, it’s #pseudomonas. new study from our lab out as a preprint describing a complete TRIS degradation pathway in #bacteria biorxiv.org/content/10.1101/20 #microbiology #HGT #biorxiv

  31. Ever wondered why your #TRIS-buffered solutions turn turbid on the shelf so quickly? Look no further, it’s #pseudomonas. new study from our lab out as a preprint describing a complete TRIS degradation pathway in #bacteria biorxiv.org/content/10.1101/20 #microbiology #HGT #biorxiv

  32. Excellent opportunity for anyone wanting to undertake a postdoc in #phage research, with Professor Andrey Shkoporov twitter.com/AShkoporov at University College Cork. Contact Andrey directly about this position.

    #microbiome #virome #HGT

  33. Excellent opportunity for anyone wanting to undertake a postdoc in #phage research, with Professor Andrey Shkoporov twitter.com/AShkoporov at University College Cork. Contact Andrey directly about this position.

    #microbiome #virome #HGT

  34. Excellent opportunity for anyone wanting to undertake a postdoc in #phage research, with Professor Andrey Shkoporov twitter.com/AShkoporov at University College Cork. Contact Andrey directly about this position.

    #microbiome #virome #HGT

  35. Excellent opportunity for anyone wanting to undertake a postdoc in #phage research, with Professor Andrey Shkoporov twitter.com/AShkoporov at University College Cork. Contact Andrey directly about this position.

    #microbiome #virome #HGT

  36. This is super cool... and a great example of Horizontal Gene Transfer #HGT pnas.org/doi/10.1073/pnas.2305

  37. This is super cool... and a great example of Horizontal Gene Transfer #HGT pnas.org/doi/10.1073/pnas.2305

  38. This is super cool... and a great example of Horizontal Gene Transfer #HGT pnas.org/doi/10.1073/pnas.2305

  39. This is super cool... and a great example of Horizontal Gene Transfer #HGT pnas.org/doi/10.1073/pnas.2305

  40. .> Yet wrapped up in penicillin’s serendipitous beginnings were hints of challenges to come. “It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them,” Fleming warned in 1945 when he received the Nobel Prize in medicine or physiology, together with Florey and Chain, “and the same thing has occasionally happened in the body.”
    .> His remarks proved ominously prescient: penicillin-resistant strains of S. aureus began appearing in hospitals just years after the drug was introduced.
    ...
    .> But even Fleming did not anticipate the magnitude of the resistance problem to come. In the 1950s, amid postwar outbreaks of dysentery, Japanese researchers led by Tsutomu Watanabe began to encounter bacteria simultaneously resistant to multiple drugs—impossibly unlikely for pathogens acquiring random mutations. By 1955, researchers were reporting several strains of Shigella dysenteriae resistant to the same four antibiotics at once. Even worse, the resistance itself was contagious. Related species, when mixed with multidrug-resistant S. dysenteriae, also became resistant to multiple antibiotics.
    .> “Resistance works differently in the bacterium,” explains Stuart Levy
    - https://www.harvardmagazine.com/2014/05/superbug
    #AlexanderFleming #Penicillin #TsutomuWatanabe #WatanabeTsutomu #StuartLevy #Antibiotics #AntibioticResistnace #HGT #HorizontalGeneTransfer