#retrotransposons — Public Fediverse posts

A retroelement-derived mammalian ARC protein exhibits selective RNA recognition and nucleic acid chaperone functions.

#TEs #Transposons #Retrotransposons #ARC #ActivityRegulatedCytoskeletonAssociatedProtein #Ty3

https://academic.oup.com/nar/article/54/5/gkag207/8511734

A retroelement-derived mammalian ARC protein exhibits selective RNA recognition and nucleic acid chaperone functions.

#TEs #Transposons #Retrotransposons #ARC #ActivityRegulatedCytoskeletonAssociatedProtein #Ty3

https://academic.oup.com/nar/article/54/5/gkag207/8511734

Animal retrozymes are non-autonomous sequences of Penelope-like elements.

#TEs #Transposons #Retrotransposons #Retrozymes #PenelopeLikeElemens #PLEs #Preprint

https://www.biorxiv.org/content/10.64898/2026.07.22.740005v1

Animal retrozymes are non-autonomous sequences of Penelope-like elements.

#TEs #Transposons #Retrotransposons #Retrozymes #PenelopeLikeElemens #PLEs #Preprint

https://www.biorxiv.org/content/10.64898/2026.07.22.740005v1

Plants repress ROS1 expression to attenuate heat-induced transposon burst.

#Transposons #Retrotransposons #ROS1 #RepressorOfSilencing1 #HeatStress #ONSEN #Arabidopsis #PlantScience

https://www.nature.com/articles/s41477-025-02076-9

Plants repress ROS1 expression to attenuate heat-induced transposon burst.

#Transposons #Retrotransposons #ROS1 #RepressorOfSilencing1 #HeatStress #ONSEN #Arabidopsis #PlantScience

https://www.nature.com/articles/s41477-025-02076-9

Spatiotemporal Tracking of Three Novel Transposable Element Invasions in Drosophila melanogaster over the Last 30 Years.

#Transposons #Retrotransposons #TEinvasion #HorizontalTransposonTransfer #HGT #Drosophila

https://academic.oup.com/mbe/article/42/7/msaf143/8157961

Spatiotemporal Tracking of Three Novel Transposable Element Invasions in Drosophila melanogaster over the Last 30 Years.

#Transposons #Retrotransposons #TEinvasion #HorizontalTransposonTransfer #HGT #Drosophila

https://academic.oup.com/mbe/article/42/7/msaf143/8157961

A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration.

#Transposons #Retrotransposons #SVA #XLinkedDystoniaParkinsonism #XDP #Neurodegeneration #Organoids #ShortTandemRepeats #Rloops #AntisenseNucleotides

https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00583-2

A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration.

#Transposons #Retrotransposons #SVA #XLinkedDystoniaParkinsonism #XDP #Neurodegeneration #Organoids #ShortTandemRepeats #Rloops #AntisenseNucleotides

https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00583-2

A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration.

#Transposons #Retrotransposons #SVA #XLinkedDystoniaParkinsonism #XDP #Neurodegeneration #Organoids #ShortTandemRepeats #Rloops #AntisenseNucleotides

https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00583-2

A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration.

#Transposons #Retrotransposons #SVA #XLinkedDystoniaParkinsonism #XDP #Neurodegeneration #Organoids #ShortTandemRepeats #Rloops #AntisenseNucleotides

https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00583-2

Safeguarding spermatogenesis from retrotransposon insertions by forming ecDNA.

#Transposons #Retrotransposons #ExtrachromosomalCircularDNA #ecDNA #Spermatogenesis #Drosophila #Preprint

https://www.biorxiv.org/content/10.1101/2025.05.11.653319v1

Safeguarding spermatogenesis from retrotransposon insertions by forming ecDNA.

#Transposons #Retrotransposons #ExtrachromosomalCircularDNA #ecDNA #Spermatogenesis #Drosophila #Preprint

https://www.biorxiv.org/content/10.1101/2025.05.11.653319v1

Reactivation of retrotransposable elements is associated with environmental stress and ageing.

#Transposons #Retrotransposons #Ageing #EnvironmentalStress #Review

https://www.nature.com/articles/s41576-025-00829-y

Reactivation of retrotransposable elements is associated with environmental stress and ageing.

#Transposons #Retrotransposons #Ageing #EnvironmentalStress #Review

https://www.nature.com/articles/s41576-025-00829-y

Structural and biochemical studies of mobile retrotransposon proteins in action.

#Transposons #Retrotransposons #non-LTR #LINE1 #R2

https://www.sciencedirect.com/science/article/pii/S0959440X25000715

Structural and biochemical studies of mobile retrotransposon proteins in action.

#Transposons #Retrotransposons #non-LTR #LINE1 #R2

https://www.sciencedirect.com/science/article/pii/S0959440X25000715

Reprogramming site-specific retrotransposon activity to new DNA sites.

#Transposons #Retrotransposons #R2 #Cas9 #GenomeEditing

https://www.nature.com/articles/s41586-025-08877-4

Reprogramming site-specific retrotransposon activity to new DNA sites.

#Transposons #Retrotransposons #R2 #Cas9 #GenomeEditing

https://www.nature.com/articles/s41586-025-08877-4

Turnover of retroelements and satellite DNA drives centromere reorganization over short evolutionary timescales in Drosophila.

#Transposons #Retrotransposons #SatelliteDNA #Centromeres #Drosphila

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002911

Turnover of retroelements and satellite DNA drives centromere reorganization over short evolutionary timescales in Drosophila.

#Transposons #Retrotransposons #SatelliteDNA #Centromeres #Drosphila

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002911

Protein-free catalysis of DNA hydrolysis and self-integration by a ribozyme.

#Group2Introns #Transposons #Retrotransposons #Ribozymes #ReverseSplicing #RNAworld

https://academic.oup.com/nar/article/53/2/gkae1224/7928520

Protein-free catalysis of DNA hydrolysis and self-integration by a ribozyme.

#Group2Introns #Transposons #Retrotransposons #Ribozymes #ReverseSplicing #RNAworld

https://academic.oup.com/nar/article/53/2/gkae1224/7928520

Marine vs. terrestrial: links between the environment and the diversity of Copia retrotransposon in metazoans.
#Transposons #Retrotransposons #Ty1Copia #Metazoans
https://mobilednajournal.biomedcentral.com/articles/10.1186/s13100-025-00346-z

Marine vs. terrestrial: links between the environment and the diversity of Copia retrotransposon in metazoans.
#Transposons #Retrotransposons #Ty1Copia #Metazoans
https://mobilednajournal.biomedcentral.com/articles/10.1186/s13100-025-00346-z

Marine vs. terrestrial: links between the environment and the diversity of Copia retrotransposon in metazoans.
#Transposons #Retrotransposons #Ty1Copia #Metazoans
https://mobilednajournal.biomedcentral.com/articles/10.1186/s13100-025-00346-z

Direct cell-to-cell transmission of retrotransposons.
#Transposons #Retrotransposons #LRTs #Ty3Gypsy #Germline #Drosophila #Preprint
https://www.biorxiv.org/content/10.1101/2025.03.14.642691v2

Direct cell-to-cell transmission of retrotransposons.
#Transposons #Retrotransposons #LRTs #Ty3Gypsy #Germline #Drosophila #Preprint
https://www.biorxiv.org/content/10.1101/2025.03.14.642691v2

Structural mechanism of LINE-1 target-primed reverse transcription.
#Transposons #Retrotransposons #LINE1 #ReverseTranscription #CryoEM
https://www.science.org/doi/10.1126/science.ads8412

Structural mechanism of LINE-1 target-primed reverse transcription.
#Transposons #Retrotransposons #LINE1 #ReverseTranscription #CryoEM
https://www.science.org/doi/10.1126/science.ads8412

' #Jumping_gene' caught in the act: Advanced #imaging provides new insights into #retrotransposons.

#cryo-electron_tomography

https://phys.org/news/2025-03-gene-caught-advanced-imaging-insights.html

' #Jumping_gene' caught in the act: Advanced #imaging provides new insights into #retrotransposons.

#cryo-electron_tomography

https://phys.org/news/2025-03-gene-caught-advanced-imaging-insights.html

' #Jumping_gene' caught in the act: Advanced #imaging provides new insights into #retrotransposons.

#cryo-electron_tomography

https://phys.org/news/2025-03-gene-caught-advanced-imaging-insights.html

' #Jumping_gene' caught in the act: Advanced #imaging provides new insights into #retrotransposons.

#cryo-electron_tomography

https://phys.org/news/2025-03-gene-caught-advanced-imaging-insights.html

' #Jumping_gene' caught in the act: Advanced #imaging provides new insights into #retrotransposons.

#cryo-electron_tomography

https://phys.org/news/2025-03-gene-caught-advanced-imaging-insights.html

In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography
#Transposons #Retrotransposons #Ty1Copia #VLP #CryoET #Drosophila
https://www.cell.com/cell/fulltext/S0092-8674(25)00159-X

In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography
#Transposons #Retrotransposons #Ty1Copia #VLP #CryoET #Drosophila
https://www.cell.com/cell/fulltext/S0092-8674(25)00159-X

LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development.
#TransposableElements #Retrotransposons #LINE-1 #InducedPluripotentStemCells #BrainOrganoids #Preprint
https://www.biorxiv.org/content/10.1101/2025.01.17.633315v1

LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development.
#TransposableElements #Retrotransposons #LINE-1 #InducedPluripotentStemCells #BrainOrganoids #Preprint
https://www.biorxiv.org/content/10.1101/2025.01.17.633315v1

Interplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing

#TransposableElements #Retrotransposons #Silencing #HuSH #LINE-1

https://www.nature.com/articles/s41467-024-53761-w

Interplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing

#TransposableElements #Retrotransposons #Silencing #HuSH #LINE-1

https://www.nature.com/articles/s41467-024-53761-w

#DNA #parasite now plays key role in making critical #nerve #cell #protein

#RNA #myelin #retrotransposons #RNLTR12_int

https://arstechnica.com/science/2024/03/dna-that-was-once-a-virus-now-helps-make-a-key-protein-for-nerve-cells/

#DNA #parasite now plays key role in making critical #nerve #cell #protein

#RNA #myelin #retrotransposons #RNLTR12_int

https://arstechnica.com/science/2024/03/dna-that-was-once-a-virus-now-helps-make-a-key-protein-for-nerve-cells/

#DNA #parasite now plays key role in making critical #nerve #cell #protein

#RNA #myelin #retrotransposons #RNLTR12_int

https://arstechnica.com/science/2024/03/dna-that-was-once-a-virus-now-helps-make-a-key-protein-for-nerve-cells/

#DNA #parasite now plays key role in making critical #nerve #cell #protein

#RNA #myelin #retrotransposons #RNLTR12_int

https://arstechnica.com/science/2024/03/dna-that-was-once-a-virus-now-helps-make-a-key-protein-for-nerve-cells/

#DNA #parasite now plays key role in making critical #nerve #cell #protein

#RNA #myelin #retrotransposons #RNLTR12_int

https://arstechnica.com/science/2024/03/dna-that-was-once-a-virus-now-helps-make-a-key-protein-for-nerve-cells/

Vera Gorbunova at ARDD2023: Transcriptomic and proteomic signatures of longevity
https://youtu.be/DjYHihUfHq8?si=j73curN9IHGhuj35

I ❤️ Dr Gorbunova
I ❤️ fucoidan

I've been a fan of fucoidan for years, before I found out it is a SIRT6 activator. I started eating wakame as a source of iodine & noticed a reduction in 'aches & pains'. Then I started looking into its active constituents (besides iodine); here are my notes (now out of date) -
https://rhyobrain.blogspot.com/2020/11/wakame-and-fucoidan.html

#LINE1 #retrotransposons #SIRT6 #fucoidan #aging #inflammation #NaturalProducts #FunctionalFoods

Vera Gorbunova at ARDD2023: Transcriptomic and proteomic signatures of longevity
https://youtu.be/DjYHihUfHq8?si=j73curN9IHGhuj35

I ❤️ Dr Gorbunova
I ❤️ fucoidan

I've been a fan of fucoidan for years, before I found out it is a SIRT6 activator. I started eating wakame as a source of iodine & noticed a reduction in 'aches & pains'. Then I started looking into its active constituents (besides iodine); here are my notes (now out of date) -
https://rhyobrain.blogspot.com/2020/11/wakame-and-fucoidan.html

#LINE1 #retrotransposons #SIRT6 #fucoidan #aging #inflammation #NaturalProducts #FunctionalFoods

Vera Gorbunova at ARDD2023: Transcriptomic and proteomic signatures of longevity
https://youtu.be/DjYHihUfHq8?si=j73curN9IHGhuj35

I ❤️ Dr Gorbunova
I ❤️ fucoidan

I've been a fan of fucoidan for years, before I found out it is a SIRT6 activator. I started eating wakame as a source of iodine & noticed a reduction in 'aches & pains'. Then I started looking into its active constituents (besides iodine); here are my notes (now out of date) -
https://rhyobrain.blogspot.com/2020/11/wakame-and-fucoidan.html

#LINE1 #retrotransposons #SIRT6 #fucoidan #aging #inflammation #NaturalProducts #FunctionalFoods

Vera Gorbunova at ARDD2023: Transcriptomic and proteomic signatures of longevity
https://youtu.be/DjYHihUfHq8?si=j73curN9IHGhuj35

I ❤️ Dr Gorbunova
I ❤️ fucoidan

I've been a fan of fucoidan for years, before I found out it is a SIRT6 activator. I started eating wakame as a source of iodine & noticed a reduction in 'aches & pains'. Then I started looking into its active constituents (besides iodine); here are my notes (now out of date) -
https://rhyobrain.blogspot.com/2020/11/wakame-and-fucoidan.html

#LINE1 #retrotransposons #SIRT6 #fucoidan #aging #inflammation #NaturalProducts #FunctionalFoods

Vera Gorbunova at ARDD2023: Transcriptomic and proteomic signatures of longevity
https://youtu.be/DjYHihUfHq8?si=j73curN9IHGhuj35

I ❤️ Dr Gorbunova
I ❤️ fucoidan

I've been a fan of fucoidan for years, before I found out it is a SIRT6 activator. I started eating wakame as a source of iodine & noticed a reduction in 'aches & pains'. Then I started looking into its active constituents (besides iodine); here are my notes (now out of date) -
https://rhyobrain.blogspot.com/2020/11/wakame-and-fucoidan.html

#LINE1 #retrotransposons #SIRT6 #fucoidan #aging #inflammation #NaturalProducts #FunctionalFoods

12-Jul-2023
DNA element with a murky past is borrowing cell’s repair machinery

Circular DNA, thought to be an accidental byproduct, is borrowing the cell’s DNA repair mechanisms to copy itself

https://www.eurekalert.org/news-releases/995090

#science #CellBiology #DNA #RetroTransposons

12-Jul-2023
DNA element with a murky past is borrowing cell’s repair machinery

Circular DNA, thought to be an accidental byproduct, is borrowing the cell’s DNA repair mechanisms to copy itself

https://www.eurekalert.org/news-releases/995090

#science #CellBiology #DNA #RetroTransposons

12-Jul-2023
DNA element with a murky past is borrowing cell’s repair machinery

Circular DNA, thought to be an accidental byproduct, is borrowing the cell’s DNA repair mechanisms to copy itself

https://www.eurekalert.org/news-releases/995090

#science #CellBiology #DNA #RetroTransposons

Specific suppression of long terminal repeat retrotransposon mobilization in plants
#Retrotransposons #TransgenicPlants #GenomeInestability #Tenofovir
https://academic.oup.com/plphys/advance-article/doi/10.1093/plphys/kiac605/6965411

Then I went to @EPFL in #Lausanne #Switzerland to study the topic that got me interested in #MolecularGenetics and #EvoDevo, #HoxGenes with @DenisDuboule (#InHoxWeTrust).

Now I am a Senior Scientist at @TesseraTx in #Boston doing the #BioTech thing. I have a budding interest in #Retrotransposons and #Retroposition.

Then I went to @EPFL in #Lausanne #Switzerland to study the topic that got me interested in #MolecularGenetics and #EvoDevo, #HoxGenes with @DenisDuboule (#InHoxWeTrust).

Now I am a Senior Scientist at @TesseraTx in #Boston doing the #BioTech thing. I have a budding interest in #Retrotransposons and #Retroposition.

Then I went to @EPFL in #Lausanne #Switzerland to study the topic that got me interested in #MolecularGenetics and #EvoDevo, #HoxGenes with @DenisDuboule (#InHoxWeTrust).

Now I am a Senior Scientist at @TesseraTx in #Boston doing the #BioTech thing. I have a budding interest in #Retrotransposons and #Retroposition.

Then I went to @EPFL in #Lausanne #Switzerland to study the topic that got me interested in #MolecularGenetics and #EvoDevo, #HoxGenes with @DenisDuboule (#InHoxWeTrust).

Now I am a Senior Scientist at @TesseraTx in #Boston doing the #BioTech thing. I have a budding interest in #Retrotransposons and #Retroposition.