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#evobio — Public Fediverse posts

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  1. Rosalind Franklin was born OTD in 1920.

    Her X-ray crystallography was key to discovering DNA’s structure (her student Raymond Gosling took photo 51).

    She also studied viruses. After her untimely death, a colleague Aaron Klug continued her work and won a Nobel.

    🌱🐋🧪 #EvoBio #HistSTM #WomeninSTEM

  2. IAP proteins play central roles in regulating apoptosis - Lopes et al. show that IAP expansion in animals has repeatedly emerged through lineage-specific duplication events

    🔗 doi.org/10.1093/molbev/msag078

    #evobio #molbio

  3. Goff et al. measure collateral fitness landscapes of TEM-1 β-lactamase in conditions expected to alter protein aggregation or stability, proposing that mutational destabilization is associated with deleterious collateral fitness effects.

    🔗 doi.org/10.1093/molbev/msag106

    #evobio #molbio

  4. Li et al. present a genomic reassessment of the endangered black-and-white snub-nosed monkey, suggesting the species is divided into five genetically distinct clusters.

    🔗 doi.org/10.1093/molbev/msag104

    📷 Xinming He

    #evobio #molbio

  5. The May issue of MBE is here, featuring the work of Topaloudis et al., who evaluated genotype imputation accuracy in a large barn owl low-coverage WGS dataset.

    🔗 academic.oup.com/mbe/issue/43/5

    📷 Alex Labhardt

    #evobio #molbio

  6. Berruga-Fernández et al. show that bacterial hybrid chromosome formation driven by conjugative mobile genetic elements may be an important and widespread mechanism in the emergence and evolution of high-risk bacterial pathogens.

    🔗 doi.org/10.1093/molbev/msag085

    #evobio #molbio #bacteria

  7. Ceriotti et al. investigate the rewiring of organellar translation in the holoparasitic Balanophoraceae, revealing extreme changes in the anciently conserved machinery of plant organellar translation.

    🔗 doi.org/10.1093/molbev/msag077

    📷 Tuber and two inflorescences of the holoparasitic plant Lophophytum pyramidale collected from Parque Nacional Calilegua, Argentina

    #evobio #molbio

  8. Pinto et al. present SCINKD as a framework to identify unannotated sex chromosomes and curate diploid genome assemblies from a single individual.

    🔗 doi.org/10.1093/molbev/msag067

    #evobio #molbio #compbio

  9. Cui et al. investigate the evolutionary trajectory leading to dim-light vision in vertebrates, concluding that it evolved via three main stages of molecular adaptation, at the origins of ancestral rhodopsin pigments.

    🔗 doi.org/10.1093/molbev/msag096

    #evobio #molbio #opsin

  10. Cochetel & Cantu publish a new MBE Review on plant pangenomes, outlining major paradigms from gene-based catalogs to haplotype-resolved graphs, core and variable compartments, and how graph-based frameworks enable analyses that are difficult with single linear references.

    🔗 doi.org/10.1093/molbev/msag087

    #evobio #molbio #pangenome

  11. MBE's April issue Highlight features the article by Ewan Harney and Josefa González on transgenerational inheritance of heat shock responses in fruit flies, written by SMBE Fellow Shady Kuster.

    "A gift from a great-grand-fly—transgenerational epigenetic inheritance of heat shock response"

    🔗 doi.org/10.1093/molbev/msag083

    #evobio #molbio #epigenetics

  12. Didelot et al. present the R package DiagnoDating for diagnosing issues in a reconstructed dated phylogeny, including outlier detection, posterior predictive checking and residual analysis.

    🔗 doi.org/10.1093/molbev/msag093

    #evobio #molbio #compbio #phylogeny

  13. Bazzicalupo et al analyzed introgression in Iberian and Eurasian lynx with the application of a deep convolutional neural network, detecting specific regions of the genome with signals of gene flow in three populations of these species.

    🖌️Paula Martin Art

    🔗 doi.org/10.1093/molbev/msag086

    #evobio #molbio #introgression

  14. Böhm et al. resolve the structural basis of the NADP-malic enzyme divergence in C4 isoforms and propose that tetramerization mitigates aggregation at the high expression levels demanded by the C4 cycle.

    🔗 doi.org/10.1093/molbev/msag056

    #evobio #molbio

  15. Ewan Harney & Josefa González show evidence of transgenerational developmental plasticity as a result of heat shock in fruit flies, documenting gene expression and phenotype changes 3+ generations following heat shock.

    🔗 doi.org/10.1093/molbev/msag069

    This study is featured in our newest Highlight article, by SMBE Fellow Shady Kuster:

    Highlight: A gift from a great-grand-fly—transgenerational epigenetic inheritance of heat shock response
    🔗 doi.org/10.1093/molbev/msag083

    #evobio #molbio