#geneduplication — Public Fediverse posts

Starting #ESEB2025 a bit late, with an exciting symposium on whole genome duplication. They couldn’t fit all of the talks in, I’ll be talking on “Gene expression variability and evolutionary outcomes after whole-genome duplication in fishes” tomorrow in the Genetics symposium. #GeneDuplication #GenomeDuplication #MolecularEvolution

Starting #ESEB2025 a bit late, with an exciting symposium on whole genome duplication. They couldn’t fit all of the talks in, I’ll be talking on “Gene expression variability and evolutionary outcomes after whole-genome duplication in fishes” tomorrow in the Genetics symposium. #GeneDuplication #GenomeDuplication #MolecularEvolution

The #diatom genus Nitzschia lost photosynthesis to become free-living heterotrophs. This study shows how #HGT from marine bacteria, followed by #GeneDuplication & #neofunctionalization, allowed them to catabolize #alginate & live off brown algal polysaccharides @PLOSBiology https://plos.io/41WaW8e

The #diatom genus Nitzschia lost photosynthesis to become free-living heterotrophs. This study shows how #HGT from marine bacteria, followed by #GeneDuplication & #neofunctionalization, allowed them to catabolize #alginate & live off brown algal polysaccharides @PLOSBiology https://plos.io/41WaW8e

Nice work on functional evolution of proteins after duplication by @Landrychristian lab https://www.science.org/doi/10.1126/science.ado5719 #duplication #GeneDuplication #MolecularEvolution

Nice work on functional evolution of proteins after duplication by @Landrychristian lab https://www.science.org/doi/10.1126/science.ado5719 #duplication #GeneDuplication #MolecularEvolution

Nice work on functional evolution of proteins after duplication by @Landrychristian lab https://www.science.org/doi/10.1126/science.ado5719 #duplication #GeneDuplication #MolecularEvolution

Nice work on functional evolution of proteins after duplication by @Landrychristian lab https://www.science.org/doi/10.1126/science.ado5719 #duplication #GeneDuplication #MolecularEvolution

Nice work on functional evolution of proteins after duplication by @Landrychristian lab https://www.science.org/doi/10.1126/science.ado5719 #duplication #GeneDuplication #MolecularEvolution

We posted this cool preprint between Xmas and new year, now time for a thread about the results: Begum et al "Phylogenetic modeling provides evidence for sudden shifts in expression after small-scale duplication in vertebrates and strong support for the ortholog conjecture"
https://www.biorxiv.org/content/10.1101/2023.12.29.571877v1
#paralog #ortholog #GeneDuplication #GenomeDuplication #MolecularEvolution #phylogeny #ohnolog

We posted this cool preprint between Xmas and new year, now time for a thread about the results: Begum et al "Phylogenetic modeling provides evidence for sudden shifts in expression after small-scale duplication in vertebrates and strong support for the ortholog conjecture"
https://www.biorxiv.org/content/10.1101/2023.12.29.571877v1
#paralog #ortholog #GeneDuplication #GenomeDuplication #MolecularEvolution #phylogeny #ohnolog

Interesting preprint dating whole genome duplications in vertebrate evolution relative to hagfishes, which I had missed this Spring:
• 1 genome duplication before, 1 after hagfish divergence, +2 at the basis on cyclostomes
• nice investigation of relation between genome duplication and morphological diversification (not much).
https://www.biorxiv.org/content/10.1101/2023.04.08.536076v1.abstract
#GeneDuplication #GenomeDuplication #WGD #VertebrateEvolution #Hagfish

Interesting preprint dating whole genome duplications in vertebrate evolution relative to hagfishes, which I had missed this Spring:
• 1 genome duplication before, 1 after hagfish divergence, +2 at the basis on cyclostomes
• nice investigation of relation between genome duplication and morphological diversification (not much).
https://www.biorxiv.org/content/10.1101/2023.04.08.536076v1.abstract
#GeneDuplication #GenomeDuplication #WGD #VertebrateEvolution #Hagfish

Interesting preprint dating whole genome duplications in vertebrate evolution relative to hagfishes, which I had missed this Spring:
• 1 genome duplication before, 1 after hagfish divergence, +2 at the basis on cyclostomes
• nice investigation of relation between genome duplication and morphological diversification (not much).
https://www.biorxiv.org/content/10.1101/2023.04.08.536076v1.abstract
#GeneDuplication #GenomeDuplication #WGD #VertebrateEvolution #Hagfish

Interesting preprint dating whole genome duplications in vertebrate evolution relative to hagfishes, which I had missed this Spring:
• 1 genome duplication before, 1 after hagfish divergence, +2 at the basis on cyclostomes
• nice investigation of relation between genome duplication and morphological diversification (not much).
https://www.biorxiv.org/content/10.1101/2023.04.08.536076v1.abstract
#GeneDuplication #GenomeDuplication #WGD #VertebrateEvolution #Hagfish

Interesting preprint dating whole genome duplications in vertebrate evolution relative to hagfishes, which I had missed this Spring:
• 1 genome duplication before, 1 after hagfish divergence, +2 at the basis on cyclostomes
• nice investigation of relation between genome duplication and morphological diversification (not much).
https://www.biorxiv.org/content/10.1101/2023.04.08.536076v1.abstract
#GeneDuplication #GenomeDuplication #WGD #VertebrateEvolution #Hagfish

Marjorie Liénard: method to express invertebrate opsin proteins in vitro, allowing to show spectral shifts in opsins in butterflies, with notably 2 paralogs of LW providing differentiation in function between the dorsal and ventral parts of the eye https://www.pnas.org/doi/abs/10.1073/pnas.2008986118 #SMBE2023 #opsin #GeneDuplication #paralog

Marjorie Liénard: method to express invertebrate opsin proteins in vitro, allowing to show spectral shifts in opsins in butterflies, with notably 2 paralogs of LW providing differentiation in function between the dorsal and ventral parts of the eye https://www.pnas.org/doi/abs/10.1073/pnas.2008986118 #SMBE2023 #opsin #GeneDuplication #paralog

Rps27 and Rps27l proteins are functionally interchangeable...
have been evolutionarily retained because the divergence of their expression patterns has resulted in both genes becoming necessary for achieving adequate total expression of the RP across cell types.

#MolecularEvolution
#Subfunctionalization
#geneduplication
#evolution

https://elifesciences.org/articles/78695

Rps27 and Rps27l proteins are functionally interchangeable...
have been evolutionarily retained because the divergence of their expression patterns has resulted in both genes becoming necessary for achieving adequate total expression of the RP across cell types.

#MolecularEvolution
#Subfunctionalization
#geneduplication
#evolution

https://elifesciences.org/articles/78695

Now published in its final form: Parallel evolution of amphioxus and vertebrate small-scale gene duplications by Brasó-Vives et al
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02808-6
#EvoDevo #EvolutionaryBiology #Genomics #Amphioxus #Chordate #ortholog #paralog #GeneDuplication

Now published in its final form: Parallel evolution of amphioxus and vertebrate small-scale gene duplications by Brasó-Vives et al
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02808-6
#EvoDevo #EvolutionaryBiology #Genomics #Amphioxus #Chordate #ortholog #paralog #GeneDuplication

#introduction I'm Elise! #NSF postdoctoral fellow with David Enard (twitter @DavidEnard) #UofAEEB working on #bioinformatics methods and detecting ancient #epidemics in #bats using #popgen. I'm also interested in #statistics, #geneduplication, #toxin #adaptation, #lemurs, and #evolution (ary) #ecology in general. I mostly make bad #coding jokes, boost cool articles and interesting job/PhD/grant offers, talk about bats, and advocate for #mentalhealth care. Read below for life outside #academia: