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132 results for “spcanelon”
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Today in #Science (@sciencemagazine), Claudia Arevalo, Scott Hensley, & al develop an #mRNA–#LipidNanoparticle #vaccine encoding #hemagglutinin antigens from all 20 known #influenza A & B virus subtypes/lineages! #Vaccination protected animals challenged w/ matched & mismatched viral strains!
In the same issue, Alyson Kelvin & Darryl Falzarano write a wonderful Perspective on this important next step towards a #UniversalFluVaccine!
Article: bit.ly/Sci_abm0271
PS: bit.ly/Sci_adf0900 -
This week's special issue on #CellEngineering in #Science (@sciencemagazine) includes:
• a review on future of engineered #immunotherapies by Darrell Irvine, Marcela Maus, David Mooney, & Wilson Wong: https://bit.ly/Sci_abq6990
• a piece on engineering #bacteria for anti- #cancer therapies by
Candice Gurbati, Nick Arpaia, & Tal Danino: https://bit.ly/Sci_add9667Be sure to also check out the introduction written by my fantastic colleagues Bryan Ray & Priscilla Kelly: https://bit.ly/Sci_adf8627
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My Editor's Choice in #Science (@sciencemagazine) this week highlights work in the Journal of Clinical Investigation by Johanna Strobl, Georg Stary, & colleagues. The authors describe the effects of #tick bites on the #ImmuneSystem & develop an ex vivo #human #skin #explant model of #LymeDisease!
Editor's Choice : https://bit.ly/EC221118
Article: https://bit.ly/3USYkbR -
In #Science (@sciencemagazine) this week, the Hanahan lab shows that the #RNA-binding protein #FMRP enables #tumors to evade being attacked by #CD8TCells. It does so by both suppressing #CCL17 & promoting #Tregs via #IL33 & #M2 #macrophages via #PROS1 & #ExtracellularVesicles!
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In #Science (@sciencemagazine) this week, the Hanahan lab shows that the #RNA-binding protein #FMRP enables #tumors to evade being attacked by #CD8TCells. It does so by both suppressing #CCL17 & promoting #Tregs via #IL33 & #M2 #macrophages via #PROS1 & #ExtracellularVesicles!
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In #Science (@sciencemagazine) this week, the Hanahan lab shows that the #RNA-binding protein #FMRP enables #tumors to evade being attacked by #CD8TCells. It does so by both suppressing #CCL17 & promoting #Tregs via #IL33 & #M2 #macrophages via #PROS1 & #ExtracellularVesicles!
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Now in #Science magazine (@sciencemagazine)
Katherine Freitas, Julia Belk, Ansu Satpathy, Crystal Mackall, & colleagues use #CRISPR screen to identify MED12 & CCNC as key regulators of human #TCell activation & function. Inactivation in #CART cells leads to increased T cell expansion, #metabolic fitness, & #tumor control!
bit.ly/Sci_abn5647
Be sure to also check out the accompanying Perspective by Caitlin Zebley & Ben Youngblood:
