#cellengineering — Public Fediverse posts

Creating a GPCR family activated by an inert ligand

🧪 Evolved muscarinic GPCRs, responsive only to CNO
⚙️ Achieved cell signaling without native ligands
📊 Used mutant receptors to study signaling pathways for msd

#GPCR #MolecularEvolution #DREADD #Pharmacology #CellEngineering

https://dev.https://tnyp.me/CcS0q4hQ/m

🧬 Can cells “remember” their identity without changing their DNA?

🔗 Epigenetic memory: The role of the crosstalk between histone modifications and DNA methylation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.08.034

📚 CSBJ: https://www.csbj.org/

#Epigenetics #Chromatin #GeneRegulation #DNA #MolecularBiology #SyntheticBiology #CellEngineering #Genomics #SystemsBiology #DNAmethylation

🧬 Can cells “remember” their identity without changing their DNA?

🔗 Epigenetic memory: The role of the crosstalk between histone modifications and DNA methylation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.08.034

📚 CSBJ: https://www.csbj.org/

#Epigenetics #Chromatin #GeneRegulation #DNA #MolecularBiology #SyntheticBiology #CellEngineering #Genomics #SystemsBiology #DNAmethylation

🧬 Can cells “remember” their identity without changing their DNA?

🔗 Epigenetic memory: The role of the crosstalk between histone modifications and DNA methylation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.08.034

📚 CSBJ: https://www.csbj.org/

#Epigenetics #Chromatin #GeneRegulation #DNA #MolecularBiology #SyntheticBiology #CellEngineering #Genomics #SystemsBiology #DNAmethylation

🧬 Can cells “remember” their identity without changing their DNA?

🔗 Epigenetic memory: The role of the crosstalk between histone modifications and DNA methylation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.08.034

📚 CSBJ: https://www.csbj.org/

#Epigenetics #Chromatin #GeneRegulation #DNA #MolecularBiology #SyntheticBiology #CellEngineering #Genomics #SystemsBiology #DNAmethylation

🧬 Can cells “remember” their identity without changing their DNA?

🔗 Epigenetic memory: The role of the crosstalk between histone modifications and DNA methylation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.08.034

📚 CSBJ: https://www.csbj.org/

#Epigenetics #Chromatin #GeneRegulation #DNA #MolecularBiology #SyntheticBiology #CellEngineering #Genomics #SystemsBiology #DNAmethylation

PHC Announces Exclusive Distribution of MaxCyte® ExPERT™ Platform in Japan

Left : ExPERT ATx (For basic research)／Right : ExPERT STx (For basic research/ process development) Left : ExPERT GTx (For commercial manufacturing)／Right : ExPERT VLx …
#Japan #JP #JapanNews #basicresearch #BiomedicalDivision #CellEngineering #Chiyoda-ku #ExPERTplatform #MaxCyte #news #PHCHoldingsCorporation #Tokyo
https://www.alojapan.com/1310997/phc-announces-exclusive-distribution-of-maxcyte-expert-platform-in-japan/

PHC Announces Exclusive Distribution of MaxCyte® ExPERT™ Platform in Japan

Left : ExPERT ATx (For basic research)／Right : ExPERT STx (For basic research/ process development) Left : ExPERT GTx (For commercial manufacturing)／Right : ExPERT VLx …
#Japan #JP #JapanNews #basicresearch #BiomedicalDivision #CellEngineering #Chiyoda-ku #ExPERTplatform #MaxCyte #news #PHCHoldingsCorporation #Tokyo
https://www.alojapan.com/1310997/phc-announces-exclusive-distribution-of-maxcyte-expert-platform-in-japan/

Biotechs Partner to Boost mRNA Manufacturing

Two companies working in synthetic #biology are advancing a new process they say increases the scale and reduces costs of messenger #RNA #manufacturing.

https://sciencebusiness.technewslit.com/?p=44656

#News #Science #Business #mRNA #SyntheticBiology #Biotechnology #Chemistry #Engineering #Collaboration #Partnership #CellEngineering

This week's special issue on #CellEngineering in #Science (@sciencemagazine) includes:

• a review on future of engineered #immunotherapies by Darrell Irvine, Marcela Maus, David Mooney, & Wilson Wong: https://bit.ly/Sci_abq6990

• a piece on engineering #bacteria for anti- #cancer therapies by
Candice Gurbati, Nick Arpaia, & Tal Danino: https://bit.ly/Sci_add9667

Be sure to also check out the introduction written by my fantastic colleagues Bryan Ray & Priscilla Kelly: https://bit.ly/Sci_adf8627