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  1. BindBC-SDL has been updated to support SDL 2.28.0+!
    Go check it out: github.com/BindBC/bindbc-sdl/r

  2. In the name of transparency and organisation:
    I have started adding issues to various BindBC libraries, tagged as "enhancement", that state my future intentions for that library. I hope that this will help people understand what's in-store for each of the libraries, provide a place for discussion, and help keep me motivated, too.

  3. The latest and greatest: BindBC-bgfx 1.0 is coming out very soon! It features a new API based on bgfx’s C++ API with some slight tweaks to make it match the D style better, so it should be a lot nicer to use than before! :) and yes, it’s still auto-generated so it has full documentation!
    I’ve already converted one of my projects to using it and I’m excited to see everyone else getting to try it!

    #bindbc #dlang #foss #bgfx #programming #programminglanguages

  4. The latest and greatest: BindBC-bgfx 1.0 is coming out very soon! It features a new API based on bgfx’s C++ API with some slight tweaks to make it match the D style better, so it should be a lot nicer to use than before! :) and yes, it’s still auto-generated so it has full documentation!
    I’ve already converted one of my projects to using it and I’m excited to see everyone else getting to try it!

  5. SDL bindings v1.3.0 have been tested and the new readme is done. Release time!

  6. The -SDL 1.3 update is 99% complete, pending testing on macOS.

  7. Looking for a high-affinity #peptide binder for your favorite target?

    According to the newest paper by the group of Sebastian Pomplun, the software tool #BindCraft allows you to predict such binders with high success rates.

    pubs.acs.org/doi/10.1021/acsch
    #Chemistry #ChemBio #DrugDiscovery

  8. Die Datenverarbeitung im #Gesundheitswesen profitorientierten Unternehmen auszuliefern war, ist und bleibt eine fahrlässige Fehlentscheidung.

    Die Entwicklung quelloffener, modularer Lösungen durch NonProfit-Organisationen für nahezu identische Anwendungsfälle wäre logisch, sparsam und nachhaltig gewesen. Und hätte besonders verwundbare Menschen vor den Begehrlichkeiten der Kapitalist*innen, vor Verrat und Ausbeutung ihrer Verletzlichkeit schützen können.

    Und wir als Behandler*innen hätten uns auf's Behandeln konzentrieren können, anstatt wertvolle Zeit an individuelle Auswahlentscheidungen und Erstattungsspielchen zu verschwenden. Ohne die ewig begleitende Sorge, ob der jeweilige Anbieter seine Profitinteressen evtl. vor die vertrauenswürdige Verarbeitung sensibelster Personendaten stellt.

    Gutachter: IT-Dienstleister #BinDoc betreibt illegale Krankenhaus-Falldatenbank | #heiseOnline
    https://www.heise.de/news/Gutachter-IT-Dienstleister-BinDoc-betreibt-illegale-Krankenhaus-Falldatenbank-9785718.html?wt_mc=sm.red.ho.mastodon.mastodon.md_beitraege.md_beitraege&utm_source=mastodon

  9. Depuis sa sortie l’année dernière, BindCraft, la plateforme d'IA open source développée par le Laboratoire de conception de protéines et d’immuno-ingénierie, a déjà bouleversé le monde de la conception de protéines.

    go.epfl.ch/a6f094

    #EPFL #Protéines #IA

  10. Interesting article by the American Peptide Society about the recent publication by the group of Sebastian Pomplun of our @LED3hub on using BindCraft to predict #peptide binders to high value protein targets.
    americanpeptidesociety.org/aps

  11. Since its release last year, the open-source platform BindCraft, developed by the Laboratory of Protein Design and Immunoengineering, has already disrupted the world of protein design.

    Find out more: go.epfl.ch/b340be

    #EPFL #ProteinDesign #AI

  12. Crop protection’s next race is not biology vs chemistry. It’s a search for a broader toolbox. BASF’s AgBiTech deal, Bayer’s new herbicide push, and Bindbridge’s protein-degradation bet all point to the same shift. agtech.industryexaminer.com/cr #AgTech #CropProtection #TechNews

  13. #Optique 1.0.0 preview: runWithConfig() is gone—run() now accepts source contexts. Meta command config gets independent command/option sub-configs. bindConfig() gains config-file metadata for path resolution. #TypeScript #CLI

    dahlia/optique

  14. Interesting article by the American Peptide Society about the recent publication by the group of @[email protected] of our @[email protected] on using BindCraft to predict #peptide binders to high value protein targets. americanpeptidesociety.org/aps-news/bin...

  15. Are you interested in computationally predicting peptide binders to a protein-of interest?

    Check out this Science blog post by Derek Lowe on the work by Sebastian Pomplun of our @LED3hub on predicting peptide binders using BindCraft.

    science.org/content/blog-post/

    #Chemistry #ChemBio #Peptide #BindCraft #Prediction #DrugDiscovery

  16. #Optique 1.0.0 is shaping up, and three API changes are worth knowing about in advance.

    • Runner consolidation: run() from @optique/run now accepts source contexts directly, which makes runWith() and runWithConfig() redundant for most use cases. runWithConfig() is removed outright—no deprecation, since we have a major version to absorb the break. For the typical CLI, run() is now the single entry point.

    • Meta command config redesign: help, version, and completion in RunOptions no longer use mode: "command" | "option" | "both". Each now takes independent command and option sub-configs, which makes it possible to give --help a -h alias, hide a meta command from usage lines while keeping it in the help listing, or group the command and option forms differently. String shorthands (help: "both", version: "1.2.3", etc.) still work exactly as before.

    • Config-file-relative paths: bindConfig()'s key callback now receives config file metadata as a second argument—configDir and configPath—so you can resolve paths relative to the config file's location rather than the working directory. This matches how tools like the TypeScript compiler handle outDir and similar path options.

    More details on the 1.0.0 milestone.

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