#streptomyces — Public Fediverse posts

New publication: Inducible #CRISPRi enables efficient and high-fidelity #genome editing in #Streptomyces. #antibiotics
https://doi.org/10.1093/nar/gkag560

New publication: #Plant Coumarins #Modulate Natural Product #Biosynthesis in a #Streptomyces #Root #Endophyte.
https://doi.org/10.1021/acs.jnatprod.5c01626

More than a billion tons of #chitin are produced on Earth each year. This study shows that the soil #bacterium #Streptomyces venezuelae thrives on chitin from #insect #exoskeletons, using a potent mix of chitinases and a dedicated chitobiose importer @PLOSBiology https://plos.io/45sg4S5

Despite a century of use in #DrugDiscovery, specialized metabolism continues to amaze. Justin Nodwell explores a @PLOSBiology study that uses a novel computational approach to uncover unsuspected functions of a compound produced by #Streptomyces. Paper: https://plos.io/43UVUPB Primer: https://plos.io/4n25bOF

#Bacterial ' #jumping_genes' can target and control #chromosome ends.

#transposons #telomeres #Streptomyces #genomes

https://phys.org/news/2025-03-bacterial-genes-chromosome.html

During her work at Rutgers University microbiologist Elizabeth Bugie (1920-2001) was involved in the discovery of streptomycin, the first antibiotic effective against tuberculosis. While her boss received the Nobel Prize for this discovery, she wasn’t mentioned. Honouring her work on the discovery and evaluation of antibiotics, DSMZ researchers named the strain Streptomyces bugieae (DSM 41528) after her.

#herstory #HonoringWomenInSTEM #WomenInScience #streptomyces #microbiology #antibiotics

Fanny Hesse (1850-1934) worked unpaid for her husband Walter Hesse in Robert Koch's laboratory. Koch was desperate to find a suitable medium for growing bacterial cultures. Fanny Hesse came up with the idea of using agar, which proved to be an ideal gelling agent. To honour her for introducing agar and revolutionising microbiology, DSMZ researchers named the strain Streptomyces hesseae (DSM 40473) after her.

#herstory #HonoringWomenInSTEM #WomenInScience #RobertKoch #streptomyces #microbiology

How do #phages impact #Streptomyces physiology? @BuryMone &co show that induction of the #prophage 'Samy' enhances dispersal of #multicellular aggregates of S. ambofaciens #bacteria in response to stress, likely promoting lineage propagation #PLOSBiology https://plos.io/3LDRNib

New class of #antimicrobials discovered in #soil #bacteria.

#Streptomyces #umbrella_toxin

https://phys.org/news/2024-04-class-antimicrobials-soil-bacteria.html

How SARPs regulate #antibiotic #biosynthesis in Streptomyces. This study combines #cryoEM structures with biochemical assays to explain how the #Streptomyces coelicolor SARP AfsR activates transcription #PLOSBiology https://plos.io/3P5DWUe

Katherine Duncan from Strathclyde University:

Linking genes and metabolites for informed antibiotic discovery

#jgi2023 #actinomycetes #streptomyces #antibiotics #jgi

@LBNLBioSci

Researchers from the University of Tsukuba find that #Streptomyces phage tail-like particles are located intracellularly, unlike other contractile #injections systems, and protect the #bacterium against #osmotic #stress
#Microbiology #sflorg
https://www.sflorg.com/2023/04/mcb04142302.html

Contractile injection systems never cease to amaze 🤩
---
RT @PilhoferLab
Another Contractile Injection System? 💉🙄 BUT THIS is a special one 👈😱 Spearheaded by our postdoc @casub1 in a fantastic collab with @JWSallmenII & @SusanSchlimpert, they could demonstrate a cytoplasmic role (☠️) of CIS in #Streptomyces out now in @NatureMicrobiol 🧵1/2
https://twitter.com/PilhoferLab/status/1633863429256806401

A computational model of #Streptomyces reveals that if antibiotic production trades off with replication, genome architecture can evolve to support a mutation-driven division of labor ➡️ http://bit.ly/3XZv7gT
#evolution #multiscalemodelling #systemsbiology

we fully agree with this tweet by @ArianeBriegel :

°So proud of @VeroniqueO5
! Her paper on Reversible bacteriophage resistance by shedding the bacterial cell wall is among the top 5 cited articles in Open Biology in 2022!"

https://twitter.com/BriegelAriane/status/1620675201993437184

https://doi.org/10.1098/rsob.210379

#microbiology #Streptomyces

@laborjournal
also for ornamentation: a few #Streptomyces colonies, please 🙂

#Streptomyces fans and NAP addicts take note 👇

arrest of hyphal growth upon HU depletion + the explanation...
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1093/6845437?login=false
#microbiology

#Introduction

I'm an associate professor at #UniversityofNorthTexas in #Biology and Associate Dean for Undergraduate Studies in #UNTCollegeofScience. My professional interests are in #microbiology #bacteriophages #Streptomyces #DBER #STEMeducation #BiologyEducationResearch. Hobbies include #camping #hiking #kayaking #birdwatching #photography. All views are my own. He/Him/His.