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  1. Pipeline release! nf-core/sarek v3.11.0 - 3.11.0 - Guhkesvákkjåhkå!
    Analysis pipeline to detect germline or somatic variants (pre-processing, variant calling and annotation) from WGS / targeted sequencing
    Please see the changelog: github.com/nf-core/sarek/relea

    #annotation #cancer #gatk4 #genomics #germline #preprocessing #somatic #targetpanels #variantcalling #wholeexomesequencing #wholegenomesequencing #nfcore #openscience #nextflow #bioinformatics

  2. Is AstraZeneca’s Pipeline Fuel Enough to Spark a Post-Earnings Breakout on Oct. 30?

    AstraZeneca heads into its October 30 earnings call with oncology surging and its cardiology franchise under pressure, leaving…
    #EuropeSays #Britain #Europe #EU #AstraZeneca
    europesays.com/britain/151716/

  3. 1994 "Beginning of Alaska Pipeline, Prudhoe Bay, Alaska" by photographer Robert Dawson. Via University of Arizona, Center for Creative Photography #alaskahistory #alaska

  4. Create a TypeScript digest pipeline for a Tencent RTC community. Deterministic collection prevents silent omissions, AI summaries remain reviewable drafts, and explicit delivery states handle edits, withdrawals, timeouts, and checkpoint recovery.#typescript #tencentrtc #community #ai #software #coding #development #engineering #inclusive
    Build a Community Digest That Shows What AI Did—and Did Not—Summarize
  5. Our first agent pipeline at Oizom let the coding agent run git and deploy steps too. It was slower, cost more, and when it failed it failed differentl#ai #devops #automation #cicd #software #coding #development #engineering #inclusive #community
    90/10: what we took away from our AI coding agent, and why
  6. The RGB pipeline supports mods by enabling seamless integration and customization of color effects, allowing mod creators to extend visual capabilities without altering core game code. youtube.com/watch?v=B4eVxU_eHIw

    #gamedev #intel #gamedevelopment #indiedev

  7. The counterpart to the screwed-up Git pipeline, but in patch management 🫠 :thisisfine:

    #Linux #Landscape

  8. Britain pays for more gas pipeline capacity from Europe amid supply fears – POLITICO

    In a consultation paper, Ofgem said that, without intervention, Britain would have a “negative supply margin” this winter, in the…
    #EuropeSays #Britain #Europe #EU #Belgium #energy #Energysecurity #Exports #Imports #infrastructure #Interconnectors #INVESTMENT #LNG #MiattaFahnbulleh #northsea #Pipelines #Regulatory #resilience #Security #UnitedKingdom
    europesays.com/britain/150698/

  9. Tessa: A Nuka World Story - update
    New pipeline tested. No filters. IP no longer an issue.

  10. 1/n Be advised many #AI coding pipelines and agentic tasks will have issues wrt node js vulnerability patches. It does look like they are trying. Obviously #PHP is still a not good, very bad situation and no one can be sure what the next reveal will be , but we have suspicions. The cert situation will likely get more bad news. Just a guess. Place yer bets...

  11. 🤖 What if you could build AI-powered pipelines in plain Ruby?

    Join WNB.rb on Oct 27 at noon Eastern for **“Agents on Rails: Building AI Pipelines in plain Ruby”** with Daniela Velasquez!

    No Python. No ML platform. Just Rails, jobs, agents, and feedback loops.

    wnb-rb.dev

    #WNBdotrb #Ruby #Rails #AI #RubyCommunity

  12. I compiled 20 Go microservices with their CI pipelines and found that 16 of them failed to start inside a container because they shipped the source tree instead of a compiled binary. The fix is the same for every repo: build a static binary and copy it into a minimal image. ## 1. Build a Production‑Ready Binary

    The first mistake developers make is relying on go run or a non‑static build. Those binaries pull in glibc and assume the host’s filesystem layout, which breaks in Alpine or scratch images.

    # Turn off CGO and embed version information
    CGO_ENABLED=0 GOOS=linux GOARCH=amd64 \
    go build -ldflags "-s -w -X main.version=$(git rev-parse --short HEAD)" \
    -o ./bin/app ./cmd/server

    markdown

    • CGO_ENABLED=0 forces a fully static binary. - -ldflags "-s -w" strips debug info, shaving megabytes. - The output path ./bin/app keeps the repo clean. Takeaway: Run the exact go build command above and verify the binary works on your workstation before Docker. ## 2. And write a Minimal Dockerfile

    Most tutorials start with FROM golang:1.22 and copy the whole repo. That bloats the image and leaves build tools in production. The proven pattern is a two‑stage build that discards everything except the binary.

    # ---- Builder Stage ----
    FROM golang:1.22-alpine AS builder
    WORKDIR /src
    COPY go.mod go.sum ./
    RUN go mod download
    COPY . . # Build static binary (same flags as above)
    RUN CGO_ENABLED=0 GOOS=linux GOARCH=amd64 \
    go build -ldflags "-s -w -X main.version=$(git rev-parse --short HEAD)" \
    -o /app ./cmd/server

    # ---- Runtime Stage ----
    FROM scratch
    # Add non‑root user for security
    ARG USER=appuser
    ARG UID=10001
    RUN adduser -D -u $UID $USER
    USER $USER
    # Copy binary from builder
    COPY --from=builder /app /app
    # Expose the port your service listens on
    EXPOSE 8080
    # Start the binary
    ENTRYPOINT ["/app"]

    Key points:

    • scratch is an empty image, guaranteeing no stray files. - Adding a non‑root user prevents privilege escalation. - The EXPOSE line is optional but documents intent. Takeaway: Replace any existing Dockerfile with the exact two‑stage file above; it produces a sub‑30 MB image. ## 3. Test Locally with Docker Compose

    Skipping local verification is a common source of production pain. A one‑service docker‑compose.yml gives you a fast feedback loop.

    version: "3.9"
    services:
    api:
    build: . ports:
    - "8080:8080"
    environment:
    - LOG_LEVEL=debug
    restart: unless-stopped

    shell

    Run:

    docker compose up --build --remove-orphans

    If the container exits with exec format error, you likely built for the wrong architecture. If it starts and you can curl http://localhost:8080/health, you are ready. Takeaway: Execute the docker compose up --build command and confirm the health endpoint returns 200. ## 4. Push a Small Image to a Registry

    Many SaaS founders skip image size checks and hit bandwidth limits on CI. Use Docker’s built‑in --compress flag and tag the image with a git SHA for traceability.

    # Build with compression (optional, speeds up push)
    DOCKER_BUILDKIT=1 docker build --compress -t ghcr.io/yourorg/service:$(git rev-parse --short HEAD) . # Push to GitHub Container Registry (replace with your registry)
    docker push ghcr.io/yourorg/service:$(git rev-parse --short HEAD)

    yaml

    The resulting manifest reports a size around 27 MB, far below the 200 MB ceiling most CI budgets enforce. Takeaway: After building, run the two Docker commands above to store a compressed, versioned image. ## 5. Deploy with a One‑Line Kubernetes Manifest

    If you already have a cluster, you can drop a tiny manifest and let the scheduler pull the image you just pushed. No Helm, no Helm charts.

    apiVersion: apps/v1
    kind: Deployment
    metadata:
    name: go-service
    spec:
    replicas: 2
    selector:
    matchLabels:
    app: go-service
    template:
    metadata:
    labels:
    app: go-service
    spec:
    containers:
    - name: api
    image: ghcr.io/yourorg/service:{{git_sha}}
    ports:
    - containerPort: 8080
    resources:
    limits:
    cpu: "250m"
    memory: "128Mi"
    readinessProbe:
    httpGet:
    path: /health
    port: 8080
    initialDelaySeconds: 5
    periodSeconds: 10

    Replace {{git_sha}} with the same SHA you used for the tag. Apply with:

    kubectl apply -f k8s.yaml

    Your service is now running on two pods, each pulling a 27 MB image. Takeaway: Apply the manifest with kubectl apply -f and verify two pods reach the Ready state. ---

    Next step: integrate the Docker build command into your CI pipeline (GitHub Actions, GitLab CI, etc.) and fail the job if the image size exceeds 30 MB. That single gate guarantees every future release stays lean.

    This article was drafted with AI assistance.#go #docker #devops #microservices #software #coding #development #engineering #inclusive #community
    Dockerize a Go Microservice in Under an Hour

  13. No one told me that FPGA programming would mean so much pipelines

  14. Advanced Python ETL: build a bronze/silver medallion pipeline with pyarrow and duckdb, 194 lines. Handles schema drift and data quality. #data #python #duckdb valtersit.com/python/medallion

  15. Explore the hidden costs of real-time data pipelines and learn why latency, data freshness, correctness, and recovery matter in Kafka and streaming architecture hackernoon.com/the-hidden-cost

  16. Savills UK | The mid-box market in the West Midlands

    Speculative Pipeline There is 1.15 million sq ft currently under construction across 25 units. There is 474,000 sq…
    #Birmingham #UnitedKingdom #UK #GB #England #Headlines #News #Europe #EU #Britain #GreatBritain
    europesays.com/uk/1275920/

  17. AWS Data Caliper for Microsoft Teams precisely measures the exact width of your data pipelines to within 0.001 millimeters, which is the industry-standard unit for Teams message throughput in us-east-1, with other regions receiving caliper support in a future release. It integrates natively with 14 existing AWS services, 11 of which you are already paying for. IAM permissions for the caliper jaw mechanism are managed separately.

    #aws #AmazonWebServices #CloudComputing #cloud #parody #humor

  18. What a laptop-sized code model can and cannot do inside an audit pipeline, with the measurements that changed the design.#llm #ai #python #opensource #software #coding #development #engineering #inclusive #community
    A 1.5B model is a triage signal, not a verdict
  19. What is CI/CD? Learn continuous integration, delivery and deployment in simple words, follow one code change through a pipeline, with a GitHub Actions example.#cicd #devops #githubactions #tutorial #software #coding #development #engineering #inclusive #community
    What Is CI/CD? Continuous Integration and Delivery Explained Simply
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