#sublineages — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #sublineages, aggregated by home.social.
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Neutralizing #Activity and Viral #Escape of #Pemivibart by #SARS-CoV-2 #JN1 #sublineages
Source: BioRxIV, AbstractPemivibart (Pemgarda/VYD222) was granted Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration (FDA) on March 22, 2024, for COVID-19 pre-exposure prophylaxis in immunocompromised individuals. However, its efficacy and resistance against JN.1 sublineages have yet to be fully characterized. Here, we first assessed the neutralizing…
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#Pemivibart is less active against recent #SARS-CoV-2 #JN1 #sublineages http://biorxiv.org/cgi/content/short/2024.08.12.607496v1?rss=1
Pemivibart neutralized both JN.1 and #KP2 in vitro with comparable activity, whereas its potency was decreased slightly against #LB1, #KP23, and #KP3 but substantially against #KP311. Critically, the 50% inhibitory concentration of pemivibart against KP.3.1.1 was ~6 g/mL, or ~32.7 fold higher than that of JN.1.
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Bivalent booster is 4x better against BA.5 in older adults, Pfizer says - Enlarge (credit: Getty | Future Publishing)
The new bivalent C... - https://arstechnica.com/?p=1895502 #infectiousdisease #antibodylevels #publichealth #olderadults #sublineages #subvariants #vaccination #antibodies #sars-cov-2 #biontech #bivalent #covid-19 #medicine #vaccines #science #biology #booster #omicron #viruses #bq.1.1 #pfizer #ba.4 #ba.5 #bq.1