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#oxphos — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #oxphos, aggregated by home.social.

  1. Upregulating #mitochondrial Ca2+ uniporter (MCU) helps #ColorectalCancer cell growth, but what about its regulators? Study shows that MICU2 ensures metabolic flexibility between #glycolysis & #OxPhos and regulates #cancer cell proliferation #PLOSBiology plos.io/40pW69s

  2. What is the role of #DNAdamage #kinase #DNAPKcs in the cellular response to #oxidative stress?

    Benjamin Chen at UT Southwestern, Hsinyu Lee at National Taiwan University, and coworkers implicate it as part of a #checkpoint that modulates #ANT2-#VDAC2-mediated ADP-ATP exchange over #mitochondrial membranes to limit #OXPHOS-derived ROS

    embopress.org/doi/10.15252/emb

  3. What is the role of #DNAdamage #kinase #DNAPKcs in the cellular response to #oxidative stress?

    Benjamin Chen at UT Southwestern, Hsinyu Lee at National Taiwan University, and coworkers implicate it as part of a #checkpoint that modulates #ANT2-#VDAC2-mediated ADP-ATP exchange over #mitochondrial membranes to limit #OXPHOS-derived ROS

    embopress.org/doi/10.15252/emb

  4. What is the role of #DNAdamage #kinase #DNAPKcs in the cellular response to #oxidative stress?

    Benjamin Chen at UT Southwestern, Hsinyu Lee at National Taiwan University, and coworkers implicate it as part of a #checkpoint that modulates #ANT2-#VDAC2-mediated ADP-ATP exchange over #mitochondrial membranes to limit #OXPHOS-derived ROS

    embopress.org/doi/10.15252/emb

  5. What is the role of #DNAdamage #kinase #DNAPKcs in the cellular response to #oxidative stress?

    Benjamin Chen at UT Southwestern, Hsinyu Lee at National Taiwan University, and coworkers implicate it as part of a #checkpoint that modulates #ANT2-#VDAC2-mediated ADP-ATP exchange over #mitochondrial membranes to limit #OXPHOS-derived ROS

    embopress.org/doi/10.15252/emb

  6. Recent studies have shown that #AcuteMyeloidLeukemia favors #OxPhos metabolism. This #ASH22 abstract from my colleagues demonstrates with in vitro and in vivo models that the use of #ammocidin, an inhibitor of electron transport chain complex V, works synergistically with low-dose #venetoclax to kill #AML cells. Stop by poster 2652 or read more about it here: ashpublications.org/blood/arti #leukemia #cancer #oncology #hematology #hemonc #science #medicine